Third Assisi Workshop on Biomarkers in the early diagnosis ... · 16:45 – 17:00 Coffee break...
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Third Assisi Workshop on Biomarkers in the early diagnosis of neurodegenerative disorders Congress Centre Roseo Hotel Assisi Assisi, 21-23 May 2015 Organized by Paolo Calabresi and Lucilla Parnetti Clinica Neurologica, Università degli Studi di Perugia
Transcript of Third Assisi Workshop on Biomarkers in the early diagnosis ... · 16:45 – 17:00 Coffee break...
Third Assisi Workshop onBiomarkers in the early diagnosisof neurodegenerative disorders
Congress Centre Roseo Hotel AssisiAssisi, 21-23 May 2015
Organized by Paolo Calabresi and Lucilla Parnetti
Clinica Neurologica, Università degli Studi di Perugia
E’ STATO RICHIESTO IL PATROCINIO DI:
SIN Società Italiana di Neurologia
SINDEM Associazione Autonoma Aderente alla SIN per le Demenze
DISMOV-SIN Associazione Italiana Disturbi del Movimento e Malattia di Parkinson
LIMPE Lega Italiana per la lotta contro la Malattia di Parkinson, le Sindromi Extrapiramidali e le Demenze
SINS Società Italiana di Neuroscienze
UNIVERSITA’ DEGLI STUDI DI PERUGIA Scuola di Medicina REGIONE UMBRIA Assessorato alla Sanità
AZIENDA OSPEDALIERA SANTA MARIA DELLA MISERICORDIA DI PERUGIA
FACU
LTY ANDREASSON ULF GÖTEBORG SWEDEN
BARONE PAOLO SALERNO ITALYBECCARI TOMMASO PERUGIA ITALYBEZARD ERWAN BORDEAUX FRANCEBLENNOW KAJ GÖTEBORG SWEDENBROOKS DAVID AARHUS DENMARKBRUNI AMALIA LAMEZIA TERME ITALYBURATTI EMANUELE TRIESTE ITALYCALABRESI PAOLO PERUGIA ITALYCHIASSERINI DAVIDE PERUGIA ITALYCOART ELISABETH GENT BELGIUMDECRESSAC MICKAEL NAPOLI ITALYDI FILIPPO MASSIMILIANO PERUGIA ITALYEL AGNAF OMAR MUKHTAR DOHA QATAREMILIANI CARLA PERUGIA ITALYEUSEBI PAOLO PERUGIA ITALYFORLONI GIANLUIGI MILANO ITALYGALIMBERTI DANIELA MILANO ITALYGARDONI FABRIZIO MILANO ITALYJELLINGER KURT WIEN AUSTRIAKLUENEMANN HANS WENZENBACH GERMANYLEWCZUK PIOTR ERLANGEN GERMANYOBESO JOSE MADRID SPAINOTTO MARKUS ULM GERMANYOUTEIRO TIAGO FLEMING GÖTEBORG SWEDENPADOVANI ALESSANDRO BRESCIA ITALYPARNETTI LUCILLA PERUGIA ITALYPICCONI BARBARA ROMA ITALYPISANI ANTONIO ROMA ITALYSAFTIG PAUL KIEL GERMANYSCARPINI ELIO ANGELO MILANO ITALYSCHAPIRA ANTHONY LONDON UNITED KINGDOMSTANZIONE PAOLO ROMA ITALYSTOCCHI FABRIZIO ROMA ITALYTAGLIAVINI FABRIZIO MILANO ITALYTAMBASCO NICOLA PERUGIA ITALYTOZZI ALESSANDRO PERUGIA ITALYVAN DE BERG WILMA AMSTERDAM THE NETHERLANDS
14:30 - 15:00 Welcome addresses from Paolo Calabresi, Lucilla Parnetti and Local Authorities
15:00 – 19:30 SESSION 1: “Molecular mechanisms of oligomeropathies”
15:00 - 16:45 SESSION 1A
Chairpersons: Paolo Calabresi, Daniela Galimberti Gianluigi Forloni “The concept of oligomeropathy”
Omar El Agnaf “Alpha synuclein in PD and other neurodegenerative disorders”
Tiago Outeiro “Glycation: a bitter sweet modification in synucleinopathies”
16:45 – 17:00 Coffee break
17:00 – 17:45 Magistral Lecture Introduced by Markus Otto
Kaj Blennow “CSF biomarkers for AD - current status and future perspectives: novel biomarkers for mechanistic understanding”
17:45 - 19:30 SESSION 1B
Chairpersons: Omar El Agnaf, Gianluigi Forloni Emanuele Buratti “Use of TDP-43 for biomarker and disease-modeling analyses”
Fabrizio Tagliavini “CSF beta amyloid profiles in Alzheimer’s Disease”
Erwan Bézard “Targeting alpha-synuclein as a possible therapeutic option”
19:15 – 19:30 Discussion
20:30 Dinner
THURSDAY 21, AFTERNOON
8:30 – 9:10 Special topic Paolo Eusebi, Els Coart “Comparing and combining biomarkers in research setting and clinical practice: statistical issues”
9:10 – 13:30 SESSION 2: “Synaptopathies”
9:10 - 10:40 SESSION 2A
Chairpersons: Piotr Lewczuk, Lucilla Parnetti Markus Otto “CSF synaptic biomarkers in frontotemporal lobar degeneration”
Ulf Andreasson “CSF biomarkers for AD - from research biomarkers to validated biomarkers: the long road of standardisation.”
Barbara Picconi “Dyskinesia as model of synaptopathy”
10:40 – 11:00 Coffee break
11:00 – 11:45 Magistral Lecture Introduced by Lucilla Parnetti Kurt Jellinger “Candidate Biomarkers in Multiple System Atrophy”
11:45 - 13:15 SESSION 2B Chairpersons: Paolo Stanzione, Nicola Tambasco
David Brooks “Imaging synaptopathies”
Massimiliano Di Filippo, Alessandro Tozzi “Inflammation and synaptopathies”
Fabrizio Gardoni “Synaptopathies and NMDA receptors subunits”
13:15 – 13:30 Discussion
13:30 – 14:30 Lunch
FRIDAY 22, MORNING
FRIDAY 22, AFTERNOON
14:30 – 19:00 SESSION 3: “Autophagy-lysosomal pathways in neurodegenerative diseases”
14:30 – 16:15 SESSION 3A
Chairpersons: Amalia Bruni, Carla Emiliani Paul Saftig “ Lysosomes in neuronal cells: principles and pathological functions” Mickael Decressac “Cross-talk between alpha synuclein and lysosomal system in PD”
Hans Klunemann “New insights on Niemann-Pick disease”
16:15 – 16:30 Coffee break
16:30 – 17:15 Magistral Lecture Introduced by José Obeso
Anthony Schapira “Glucocerebrosidase and Parkinson disease”
17:15 – 19:00 SESSION 3B
Chairpersons: Paul Saftig, Anthony Schapira
Wilma van de Berg “Alpha-synuclein aggregation and degradation
in Parkinson’s disease”
Davide Chiasserini “Lysosomal enzymes as candidate biomarkers for neurodegenerative diseases”
Tommaso Beccari “Origin of CSF lysosomal enzymes”
19:00 - 19:15 Discussion
20:30 Dinner
08:30 - 13:00 SESSION 4: “An update on pharmacological approaches to Alzheimer’s disease and Parkinson’s disease”
08:30 – 10:15 SESSION 4A
Chairpersons: Paolo Barone, Fabrizio Tagliavini
Piotr Lewczuk “Diagnostic role of the CSF Aß42/40 ratio in AD”
Elio Scarpini “Disease modifying therapies for Alzheimer’s disease”
Alessandro Padovani “Role of neuroimaging as selection criterion for disease modifying therapies in Alzheimer’s disease”
10:15 – 11:00 Magistral Lecture Introduced by Paolo Calabresi
José Obeso ”Selective vulnerability and the onset and progression of Parkinson’s disease”
11:00 – 12:45 SESSION 4B
Chairpersons: Alessandro Padovani, Fabrizio Stocchi
Antonio Pisani “Impact of genetic animal models to develop new therapeutic strategies in PD”
Paolo Barone “Natural history of non-motor symptoms in Parkinson’s disease”
Fabrizio Stocchi “Early diagnosis for early treatment in Parkinson disease”
12:45 – 13:00 Discussion
13:00 Closing remarks Paolo Calabresi and Lucilla Parnetti
Farewell brunch
SATURDAY 23, MORNING
SEGRETERIA SCIENTIFICA
Dr. Davide Chiasserini, Dr. Paolo EusebiTel. 075.585.8213 - 585.3545Clinica Neurologica Ospedale Santa Maria della Misericordia - PerugiaE-mails: [email protected] ; [email protected]
SEGRETERIA ORGANIZZATIVA E PROVIDER ECM
CONSULTA UMBRIAVia R. Gallenga, 206127 PerugiaTel. 075 5000066Fax 075 5153466e-mail: [email protected]
SEDE DEL CONVEGNO
Roseo Hotel AssisiVia G. Renzi, 2 - Assisi PG
INFORMATION
MODALITA’ DI PARTECIPAZIONE
Per partecipare al convegno è necessario collegarsi al sito internet www. consultaumbria.com e compilare il form on-line
• Quota di iscrizione per partecipazione medici residenziali Euro 600,00 (+ iva 22%) comprende : partecipazione ai lavori, kit congressuale, attestato di partecipazione e crediti ECM, due pernottamenti, coffee/breaks e pranzi, come da programma, cene.
• Quota di iscrizione per partecipazione medici locali Euro 350,00 (+ iva 22%)comprende : partecipazione ai lavori, kit congressuale, attestato di partecipazione e crediti ECM coffee/breaks e pranzo come da programma, cena del 22 maggio.
• Quota di iscrizione per partecipazione giovani medici (under 40) Euro 50,00 (+ iva 22%)comprende : partecipazione ai lavori, kit congressuale, attestato di partecipazione e crediti ECM coffee/breaks e pranzo come da programma.
ECML’evento è stato accreditato ECM per le seguenti figure professionali :
• Biologo
• Psicologo • Medico Chirurgo con specializzazione in Neurologia; Neurofisiopatologia; Genetica Medica; Geriatria; Biochimica Clinica; Patologia Clinica (Laboratorio di analisi chimico- cliniche e microbiologia).
Rif. Nr. 124939Crediti Assegnati 17
NOTE
EVENTO REALIZZATO CON IL CONTRIBUTO EDUCAZIONALE NON CONDIZIONANTE DI:
