Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President,...

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Thimerosal and Aspartame Thimerosal and Aspartame as cofactors in the as cofactors in the Autism Epidemic Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director, Hyperbaric Medical Center, New Mexico Medical Director, Hyperbaric Oxygen Clinic Sacramento

Transcript of Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President,...

Page 1: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Thimerosal and Aspartame as Thimerosal and Aspartame as cofactors in the Autism Epidemiccofactors in the Autism Epidemic

Kenneth Stoller, MD, FAAPPresident, International Hyperbaric Medical Assoc.

Medical Director, Hyperbaric Medical Center, New Mexico

Medical Director, Hyperbaric Oxygen Clinic Sacramento

Page 2: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The chemicals we ingest may affect more than our own health. They affect the health and vitality of future generations. The danger is that many of these chemicals may not harm us but will do silent violence to our children. Senator Abraham S. Ribicoff (l971)

The chemicals we ingest may affect more than our own health. They affect the health and vitality of future generations. The danger is that many of these chemicals may not harm us but will do silent violence to our children. Senator Abraham S. Ribicoff (l971)

Page 3: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The US is in the midst of a The US is in the midst of a DEVASTATING EPIDEMICDEVASTATING EPIDEMIC

of neurodevelopmental disorders of neurodevelopmental disorders

Page 4: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Organic mercury starts getting dumped in Minamata Bay,

Japan 1938

Page 5: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Tested only once in the 1930’s on 22 adult patients suffering from meningitis. All of the patients in this "study" died. Eli Lilly said it was safe and flooded the medical literature with fabricated articles touting Thimerosal’s healing qualities.

The Home of Ethylmercurithiosalicate

Page 6: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19651965GD Searle Chemist accidentally

discovers a substance 180 sweeter than sugar with no

caloriesAspartame

Page 7: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 8: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Pentagon lists Aspartame as prospective biochemical warfare weapon

Page 9: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1967 1967

University of Wisconsin Monkey study

Seven monkeys fed Aspartame mixed with milk. One dies, 5 have Grand Mal seizures

Dr. Harry Waisman, director Joseph P Kennedy Jr memorial Lab of Mental Retardation Research

Page 10: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1971 1971

Washington UniversitySt Louis School of Medicine

Mice studyAspartic acid, one of the

main constituents of aspartame, causes hole in the brains of infant mice

Dr. John Olney, professor of neuropathology and psychiatry

Ann Reynolds of GD Searle confirms Olney’s findings

Page 11: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

In 1973, Searle applies for FDA approval and submits over 100 studies it claims support aspartame’s safety

Neither the dead monkeys nor the mice with holes in their brains are included in the submission.

In 1973, Searle applies for FDA approval and submits over 100 studies it claims support aspartame’s safety

Page 12: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1973, Dr Martha Freeman of the FDA Division of Metabolic and Endocrine Drug Products sends

Memo:

Neither the dead monkeys nor the mice with holes in their brains are included in the submission.Information submitted by Searle inadequate with regard to the toxic breakdown product diketopiperazine (DKP)

Page 13: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Neither the dead monkeys nor the mice with holes in their brains are included in the submission.

1974

Dr John Olney, James Turner & the group Legal Action for Buyer’s Education and Labeling

file formal objection to aspartame’s approval citing evidence it could cause brain damage, particularly in children

Dr John Olney, James Turner & the group Legal Action for Buyer’s Education and Labeling file formal objection to aspartame’s approval citing evidence it could cause brain damage, particularly in children

Page 14: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

In 1973, Searle applies for FDA approval and submits over 100 studies it claims support aspartame’s safety

HEW Secretary Caspar Weinberger appointed Schmidt Commissioner of Food and Drugs in July 1973

1974FDA commissioner Alexander Schmidt grants aspartame its first approval as a “food additive” in dry goods despite FDA scientists finding serious deficiencies in the data submitted by Searle

1974

Page 15: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

In 1973, Searle applies for FDA approval and submits over 100 studies it claims support aspartame’s safety

HEW Secretary Caspar Weinberger appointed Schmidt Commissioner of Food and Drugs in July 1973

1975Concerns about the accuracy of test data submitted to the FDA by Searle prompt Schmidt to appoint a special task force to examine irregularities in 25 key studies for aspartame.

1975

Page 16: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

In 1973, Searle applies for FDA approval and submits over 100 studies it claims support aspartame’s safety

1975Searle withdraws aspartame from the market pending results of an FDA inquiry. The inquiry board doesn’t convene for another four years

1975

Page 17: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

FDA Task Force 1976FDA Task Force 1976 500 page report of Searle’s testing procedures500 page report of Searle’s testing procedures

Schmidt: “[Searle’s studies were]

incredibly sloppy science. What we discovered was reprehensible.”

Page 18: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

FDA Task Force 1976FDA Task Force 1976 New Task force formed headed by Jerome BresslerNew Task force formed headed by Jerome Bressler

This task force would look into the

irregularities in Searle’s aspartame

studies uncovered by the original task force.

Page 19: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1977 Grand Jury1977 Grand JuryFDA chief counsel Richard Merrill requests US

Attorney‘s office to investigate whether indictments should be filed against Searle.

Page 20: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19771977While the grand jury investigation is underway, Searle‘s law firm recruits Samuel Skinner, the US attorney in charge of the investigation. Skinner takes job with Searle‘s law firm Sidley & Austin.

Page 21: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19771977The legal case is passed to William

Conlon, and despite complaints from the Justice Department, Conlon stalls the

grand jury until the statute of limitations

on the aspartame charges runs out and the investigation is

dropped.

Page 22: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19781978

Conlon leaves the Justice Depart. and joins Searle‘s law firm, Sidley & Austin

Conlon leaves the Justice

Depart. and joins Searle‘s

law firm, Sidley &

Austin

Page 23: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1977 1977 Rumsfeld CEORumsfeld CEO

Former Congressman

and Secretary of Defense under

Ford is hired to turn things around for

Searle

Page 24: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Bressler ReportBressler Report19771977

“The question you have to ask yourself is: why wasn’t greater care

taken? Why didn’t Searle, with their scientists, closely evaluate this,

knowing full well that the whole society, from the youngest to the elderly,

from the sick to the unsick…will have access

to this product.”

• Tumors were removed from live animals and then put back into the studies. • Various rats were reported alive, then dead, then alive again

Page 25: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Verrett ReportVerrett Report19771977

FDA is pressured to create another task force

to review the Bressler report. The new task force is headed by Jacqueline

Verrett.FDA publishes a report

exonerating Searle of any wrongdoing in its testing

procedures.

• Verrett will later testify to the US Senate (1987) that her team was forced into validating data from experiments that were clearly a

“disaster”

Page 26: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19791979

FDA finally holds a public board of inquiry (PBOI) - to review the objections of Olney & Turner

Page 27: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

John W. Olney, MDJohn W. Olney, MDProfessor of Psychiatry & Neuropathology, Departments of Psychiatry & Pathology, Washington University School of Medicine

Aspartame Board of Inquiry

“The FDA has a special obligation to protect children”

Page 28: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

John W. Olney, MDJohn W. Olney, MDProfessor of Psychiatry & Neuropathology, Departments of Psychiatry & Pathology, Washington University School of Medicine

Aspartame Board of Inquiry

“There is no margin of safety for the use of aspartame in the child’s diet”

Page 29: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

John W. Olney, MDJohn W. Olney, MDProfessor of Psychiatry & Neuropathology, Departments of Psychiatry & Pathology, Washington University School of Medicine

Aspartame Board of Inquiry

“Aspartame will contribute to the incidence and severity of mental retardation in fetuses and children”

Page 30: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1980 The FDA’s PBOI votes unanimously against aspartame’s approval

Neither the dead monkeys nor the mice with holes in their brains are included in the submission.

“it has not been presented with proof of reasonable certainty that aspartame is safe for use as a food additive”

Page 31: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1981 1981

Rumsfeld vows touse political rather than

scientific means to get the FDA to approve aspartame

Searle sales meeting?

Brags he will “call in his markers”

Page 32: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1981 1981

Arthur Hull Hayes, Jrpharmacologist and Defense Department contract researcher

Becomes FDA Commissioner

Page 33: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1981 1981

Arthur Hull Hayes, JrHe ignores the

recommendations of the FDA’s commission to review

the PBOI’s decision and approves aspartame to be

used in dry goods, tabletop sweetener, for breakfast

cereals, chewing gum, instant coffee, tea, and in dairy-

products

Page 34: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1981 1981 Rumsfeld CEORumsfeld CEO

Gets $12 million Bonus

Page 35: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19821982

(1982 Vol 47, No. 2 Federal Register)

ThimerosalFDA expert panel reported that THIMEROSAL was:

“toxic, caused cell damage, was not effective in killing bacteria or halting their replication”

& It’s

“not generally recognized as being safe or effective”

Page 36: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19831983Secret human studies were done in Mexico

City by Searle, an unpublished study that reportedly showed that aspartame destroyed the brain and central nervous system, and hardened the synovial fluids. Some people got brain tumors and others had seizures. A pregnant woman lost her baby.

Page 37: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1983 First carbonated beverages 1983 First carbonated beverages containing aspartame go on sale containing aspartame go on sale

in USAin USA

Secret human studies were done in Mexico City by Searle, in l983 unpublished studies that showed that aspartame destroyed the brain and central nervous system, and hardened the synovial fluids. Some people got brain tumors and others had seizures. A pregnant woman lost her baby.

1983 – First carbonated beverages containing aspartame go on sale in the USA

Page 38: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 39: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 40: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1983 1983

Arthur Hull Hayes, JrResigns as FDA

commissioner for using the General foods corporate jet multiple times (GF was and

is a major purchaser of aspartame)

Page 41: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19781978

Conlon leaves the Justice Depart. and joins Searle‘s law firm, Sidley & Austin

Hayes takes $1000/day job

at Burston-Marsteller, the

PR firm for both Searle

and Monsanto

Page 42: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19841984 FDA denies Turner & Monte’s requests for a

hearing. The FDA states it reviewed all data and

concluded that “the studies demonstrated the safety of

these (aspartame’s) components.”

But then asks the CDC to investigate a number of cases of adverse reactions to

aspartame coming into the FDA

Woodrow Monte is the Director of ASU’s Food Science & Nutrition Lab

Page 43: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 44: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1984 – CDC’s review of public 1984 – CDC’s review of public complaints complaints ““Evaluation of Evaluation of

Consumer Complaints Related to Consumer Complaints Related to Aspartame UseAspartame Use””

Notes re-challenge tests show that sensitive individuals consistently produce the same adverse symptoms each time they ingested aspartame

Page 45: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Aggressive behaviorDisorientationHyperactivityMemory lossSeizuresMood swingsCardiac arrestLiver impairmentSuicidal tendenciesDeath

REPORTED SYMPTOMS INCLUDEREPORTED SYMPTOMS INCLUDE

Page 46: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

A summary was added to this investigation that contradicted the report saying that the findings were "mild".   By virtue of this short one-paragraph summary (to a 146 page report) the term "mild death" is now a defacto part of CDC jargon

CDC coverup of the reportCDC coverup of the report

Page 47: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1984 – study at ASU in Journal of Applied Nutrition determines that soft drinks stored at elevated temperatures promote deterioration of aspartame into methanol (and DKP)

Page 48: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 49: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19851985

Monsanto, the producer of bovine growth hormone, genetically engineered soy, and the pesticide Roundup, purchases Searle for $2.7 billion

Page 50: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19851985

National Soft Drink Association objects to aspartame’s approval for carbonated beverages

Congressional Record of May 7, l985, Page S 5509, Senate

"Searle has not demonstrated to a reasonable certainty that aspartame and its degradation products are safe for use in soft drinks. ... Aspartame isinherently markedly and uniquely unstable in aqueous media. In a liquid, such as a soft drink, aspartame will degrade as a function of temperature and pH."

Section 402 of the FDC Act 21 provides a food is adulterated if itcontains, in whole or in part "...a decomposed substance or if it isotherwise unfit for food.”

Page 51: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19851985

Howard M. Metzenbaum (D-Ohio) servedfor 19 years in the U.S. Senate, where hewas a champion for working families andan active member of the Senate Labor and Judiciary Committees

Metzenbaum introduced a Bill entitled, “The Aspartame Safety Act of 1985.” He considered this the absolute minimum that Congress needed to do in order to protect the health and safety of the public.

Page 52: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19861986

US Supreme Court, lead by Justice Clarence Thomas, a former Monsanto attorney, refuses to consider arguments from consumer groups that the FDA did not follow proper procedures in approving aspartame.

Page 53: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

US Senate Hearing 1987US Senate Hearing 1987held to address the issue of aspartame safety and labelingheld to address the issue of aspartame safety and labeling

This is where it was revealed that

aspartame was once on a Pentagon list of prospective

biochemical-warfare weapons

Page 54: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Verrett reveals that while compiling its 1977 report, her team was instructed not to comment or be concerned with the validity of the studies. She states the questions of birth defects have not been answered and notes that increasing the temperature of aspartame increase DKP

US Senate Hearing 1987US Senate Hearing 1987

“It was pretty obvious that somewhere along the line, the bureau officials were working up to a whitewash.” Jacqueline Verrett

Page 55: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19891989Dr. HJ Roberts, director of the Palm Beach Institute of Medical

Research, claims that several recent aircraft

accidents involving confusion and aberrant

pilot behavior were caused by aspartame

1989

Page 56: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The The Guardian Guardian (UK)(UK)

1990 – The Guardian publishes a major investigation of aspartame and delivers to UK government officials “a dossier of evidence” (excerpts of the Bressler Report) and demands a review. Instead the The Guardian is taken to court by Monsanto and forced to apologize for printing the story.

Page 57: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1991 1991 Merck MemoMerck Memo

Los Angeles Times

“6-month old children who received shots on schedule would get a

mercury dose 87 times higher than maximum

daily consumption guideline of mercury

from fish.”

Page 58: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1991 1991 Merck MemoMerck Memo

“the mercury load appears rather large”

Maurice R. Hilleman, Internationally renowned vaccinologist (now

deceased)

Page 59: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1992

What corporations have known for some time is discussed, albeit it briefly, in the press - the “Science Mob” is for sale and most of them will keep secrets if it means keeping their jobs.

Page 60: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

HHS compiles a report listing all CDC and FDA complaints against aspartame which now accounts for 75% of all the complaints in the US adverse-reaction monitoring system.

1994

Page 61: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Betty Martini uses the Freedom of Information Act to force the FDA to release an official list of adverse effects associated with aspartame. Complaints now exceed 10,000 – the FDA states < 1% of those who have problems report it to the FDA which means over a 1 million people have been experiencing adverse effects from aspartame. 1995

Betty Martini

Page 62: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The FDA promptly announces it will not continue to collect adverse reaction reports or monitor research on aspartame. 1995

Page 63: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19961996Dr. David Kessler, FDA Commissioner, granted aspartame blanket approval to be used the same as sugar... in everything! He did so without public notification, and shortly after being requested by retired Senator Metzenbaum to initiate additional safety testing.

Now Dean of Yale Med School

Page 64: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Olney publishes peer-reviewed research showing that brain tumor rates have risen in line with aspartame consumption.

1996

Page 65: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

1998

Independent scientists from the University of Barcelona publish landmark study showing aspartame is transformed into formaldehyde in the living animals and transported to all organs throughout the animal.

Page 66: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

“thimerosal-containing vaccines should be removed as soon as

possible”

Thimerosal in Vaccines: A Joint Statement of the American Academy of Pediatrics and the

Public Health Service, July 09, 1999

1999 Joint Statement1999 Joint Statement Public Health Service Public Health Service / / American Academy of PediatricsAmerican Academy of Pediatrics

Page 67: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

In 1999, the FDA stated that mercury exposure from vaccines exceeded Federal Safety Guidelines.

All federal guidelines are based upon studies of exposure tolerances to ingested methylmercury, not injected ethyl mercury, which bypasses the protecting effects of the mercury-binding protein metallothionine of the intestine. Both are organic forms of mercury that readily enter cell membrane lipid bilayers. Burbacher, et. al., demonstrated that ethylmercury rapidly leaves the blood and enters the brain where it is converted to inorganic mercury in quantities more than twice that seen with methylmercury[1] and in a form whose half-life was too long to accurately estimate. [1] TM Burbacher, et. al., Comparison of blood and brain mercury levels in infant monkeys exposed to

methylmercury or vaccines containing thimerosal. Environ Health Perspect. 2005 Aug;113(8):1015-21.

Page 68: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19991999

An investigation by The Independent on Sunday reveals that aspartame is made using a genetic engineering process.

Page 69: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

19991999

Monsanto, under pressure – not least from the worldwide resistance to genetically engineered food and ongoing lawsuits – sells Nutrasweet to JW Childs Associates, a leading private equity firm specializing in leveraged buyouts and recapitalizations.

2000

Page 70: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Simpsonwood 2000Simpsonwood 2000 Scientific Review of Vaccine Safety Datalink InformationScientific Review of Vaccine Safety Datalink Information

This top secret meeting was held to discuss a study done by

Dr. Thomas Verstraeten and his co-workers using Vaccine

Safety Datalink data as a project collaboration between

the CDC's National Immunization Program (NIP)

and four HMOs. The study examined the records of

110,000 children

Page 71: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Simpsonwood Simpsonwood 20002000

“There are just a host of neurodevelopmental data that would suggest that

we’ve got a serious problem.”

“To think there isn’t some possible problem

here is unreal.”

Bill Weil, M.D., pediatrician/nephrologist,representing

American Academy of Pediatrics’ (AAP)

The potential systemic and neurotoxic effects of thimerosal can easily be found in the Manufacturer’s Safety Data Sheets (MSDS). For example, the Eli Lilly MSDS states:

• exposure in-utero can cause mild to severe mental retardation and motor coordination impairment. • is known to cause birth defects and other reproductive harm.

Page 72: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Simpsonwood 2000Simpsonwood 2000 “…we have found

statistically significant relationships between the (mercury) exposure and (neurodevelopmental)

outcomes

for speech delays (alone) …overall test for trend is highly

statistically significant”

Tom Verstraeten, M.D., CDC’s National Immunization Program presently employed by

Glaxo-Welcome, vaccine company

Page 73: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

 Tom Verstraeten, M.D., CDC’s National Immunization Program presently employed by Glaxo-Welcome, vaccine company

Simpsonwood 2000Simpsonwood 2000

“Personally …It's true, it's

THIMEROSAL.”

Page 74: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Simpsonwood Simpsonwood 20002000

Dick Johnston, M.D., University of Colorado School of Medicine and National Jewish Center & meeting Chair

“I do not want my grandson to get a Thimerosal containing vaccine until we know better what is going on.”

Page 75: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Simpsonwood 2000Simpsonwood 2000“How on earth you are going to

handle it from here”

John Clements, World Health Organization (WHO)

“Just consider this

EMBARGOED INFORMATION,

if I can use that term, and very highly protected

information”

Roger Bernier, Ph.D., CDC’s associate director for science

Page 76: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Simpsonwood SummarySimpsonwood Summary

3) With exposure at 3 months, they found statistically significant increasing risk of neurodevelopmental disorders (including speech disorders)

1) Thimerosal-containing vaccines were associated significantly with the neurobehavioral disorder (dose related)

2) Increased risk of ADD with 12.5ug exposure

Page 77: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

What was the Public told?What was the Public told?

No consistent associations were found

between thimerosal-containing vaccine

exposure and neurodevelopmental

problems

Verstraeten, T, et al Vaccine Safety Datalink Team.: Safety of thimerosal containing vaccines: a two phased study of computerized health maintenance organization databases. Pediatrics 112, 1039-1048 (2003).

Page 78: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Iatrogenic exposure to mercury after hepatitis B vaccination in preterm infants.

(Stajiich, G. et al. J Pediatr 2000;136;679-81)

showed post-vaccination

mercury levels were

significantly higher in

preterm infants as compared with

term infants in regard to the Hepatitis B

injections at birth.

Page 79: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Using national blood mercury prevalence data from the Centers for Disease Control and Prevention, we found that between 316,588 and

637,233 children each year have cord blood mercury levels > 5.8 microg/L, a level associated with loss of IQ. The resulting loss of intelligence causes diminished economic productivity that persists

over the entire lifetime of these children .

TM Burbacher, et. al., Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal. Environ Health Perspect. 2005 Aug;113(8):1015-21.

Page 80: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2001 Institute of Medicine Report2001 Institute of Medicine Report“(The CDC) wants us to declare, well, these

things are pretty safe on a population basis,” announced Dr. Marie McCormick, Chairman of the

Immunization Safety Review .

Page 81: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2001 Institute of Medicine Report2001 Institute of Medicine Report

“... the point of no return, the line we will not cross in

public policy is to pull the vaccine,

change the schedule.”

Stated Kathleen Stratton, Ph.D, IOM staff and Study Director ISRC.

Page 82: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2001 Institute of Medicine Report2001 Institute of Medicine Report

“The committee recommends that full consideration be given

by appropriate professional societies and governmental

agencies to REMOVING THIMEROSAL

FROM VACCINESadministered to infants, children, or pregnant women in the United

States.”

Page 83: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2003 Autistic Children Poor 2003 Autistic Children Poor Mercury ExcretorsMercury Excretors

2003, Holmes et al (Reduced Levels of Mercury in First Baby Haircuts of Autistic Children, International Journal

of Toxicology,22:277–285, 2003)

Autistic children have an inability to

secrete mercury through their hair as proven by their first

haircut

Page 84: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 85: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2001- 2004 Institute of Medicine 2001- 2004 Institute of Medicine ReportsReports

Damage Control Was Required...

It was predetermined that the IOM would not find

causality between vaccines and autism or any other

neurological injury and so state same in the most unequivical manner.

Page 86: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Danish Study Buried EvidenceDanish Study Buried Evidence

emerging evidence connecting thimerosal to autism by a single network of authors

almost all beholden to a single employer.

The four published articles that are collectively known as the Danish Study compromise a deliberate and coordinated attack to bury the

Page 87: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The authors all had ties to a for-profit Danish vaccine manufacturer, the Statens Serum Instit (SSI).

This significant conflict of interest was not disclosed or reported in any of the journals that published the Danish study.

Danish Study ConflictedDanish Study Conflicted

Page 88: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Garbage In = Garbage OutGarbage In = Garbage Out ??Rise in autism rates after

removal of thimerosal??

???Concluded that thimerosal plays no role in the aetiology of autism???

Autism rates used after 1994 included children from the entire population while

Prior to 1994 only included hospitalised autistic children

Hence, the reported increase in the number of autistic

children.Madsen et al. Denmark Study(2003)

Page 89: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2004 Committee on Appropriations2004 Committee on AppropriationsUS House of Representatives: US House of Representatives:

Mercury in the Influenza VaccineMercury in the Influenza Vaccine

The news media didn’t run stories of the insanity of putting mercury in the flu vaccine that was going to be given to infants as young as 6 months old, no, they ran a scamy story about a flu vaccine shortage which resulted in a national panic.

Page 90: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

20042004The documentary that examines how inadequate food safety requirements gave birth to toxins being accepted into our food supply.

Includes interviews with Dr. Russell Blaylock, Dr. Joseph Mercola, Jim Turner, ESQ, Dr. Michael Ruff, Dr. Candace Pert, Noam Chomsky, Sheldon Rampart, Jeffrey Smith, Jack Samuels, Dr. Janet Starr Hull, Mary Nash Stoddard, Spice Williams Crosby, Bob Wall, Larry Hagman, David Getoff, Howard Glasser, Sally Fallon, Robert Scott Bell, Arthur Evangelista, Betty Martini, and many more.

Page 91: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The Ramizzini Institute in Bologna, Italy - a non-profit, private institution set up to research the causes of cancer.

Dr. Morando Soffritti who led tests at Ramizzini

A dose-related statistically significant increase of lymphomas and leukemias in female rats. This statistically significant increase was also observed at a dose level of 20 mg/Kg of body weight, a dose inferior to the accepted daily intake permitted by current regulations (50-40 mg/Kg of body weight).

2005

Page 92: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

So something had to be done and fast. Denying any link to aspartame manufacturers, the EFSA group lead by Dr Herman Koéter dismissed the Ramizzini cancer study and pronounced aspartame safe for all to consume.

But “all” have outside careers with financial ties to aspartame producers.

The 3-year Ramizzini study condemned aspartame as a "multipotential carcinogen." In the USA Merisant's sales dropped 22% and Holland Sweetener, Europe's largest aspartame producer said they were out of the aspartame business.

2006

Page 93: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 94: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The New Mexico Food Act (25-2-1 to 25-2-19 and 25-2-20 NMSA l978) on adulterated and poisonous foods is a strong, clear law with its criminal prosecution provisions for violators.

The Statute provides that: A food shall be deemed to be adulterated, (1) if it contains any poisonous or deleterious substance which may render it injurious; (2) if it contains any added poisonous or added deleterious substance which is unsafe, and (3) if it consists in whole or in part of ... decomposed substance, or if it is otherwise unfit.

Ajinomoto Corp of Japan (the world's largest aspartame and MSG manufacturer)

Just keep postponing the hearing

Page 95: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

New Mexico Senator Ortiz y Pino, February 10, sent a letter signed with 10 other state legislatures asking that Governor Richardson declare a state of Public Health Emergency on or before February 13, 2006 regarding the effects of aspartame/methanol/formaldehyde poisoning. 

Ajinomoto hired the Governor’s best friend, Walter “Butch” Maki and his affiliates, former Governor Jerry Apodaca, and former Governor David Cargo, Former House Majority Leader Richard MINZNER to make sure nothing was done to interfere with the sale of aspartame products.

Page 96: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Senator Ortiz y Pino's SB 654, the Bill to Ban the neurotoxic carcinogenic poison Aspartame from human consumption in New Mexico SB 654 was tabled in the Senate Public Affairs Committee.

The committee voted 5-2 after being heavily lobbied by COCA COLA, PEPSI COLA, "CALORIE CONTROL COUNCIL," AND AJINOMOTO.

Page 97: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

NIH, NCI halt spin on bogus aspartame study

The Calorie Control Council (CCC) has been boasting about a 1996 AARP and NIH "Diet & Health Study" they say proves aspartame doesn't cause cancer.

On April 18, 2006, Don Harkins, editor of the Idaho Observer, called the press secretary for NIH and NCI, Jennifer Thompson, to see what they think of CCC's use of AARP's "study" to exonerate aspartame. Ms. Thompson said the conclusion is "premature" and is "an interesting piece of evidence" but not scientific proof. Harkins reports:

"Thompson didn't disagree when I indicated it was irresponsible for the CCC, which has a special interest about claims aspartame is safe for human consumption, to have used the abstract from an UNPUBLISHED study to claim aspartame safety. Further, AARP isn't qualified as a scientific research entity to make any claims one way or another. That means CCC, as a special conflicted interest, has no backing for these claims. Likewise, the American Dietetic Assn. And the American Beverage Assn. are conflicted interests unsupported in their claims."

Page 98: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

WHO Strategic Group of Experts (SAGE)WHO Strategic Group of Experts (SAGE)

“WHO was extremely anxious

to preserve the production of

vaccines.

Industry is expecting clear

signals from WHO on the thimerosal

issue”

Page 99: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

WHO objectives concerning removal of thimerosal from vaccines:

1) complex activities that are costly and time consuming

2) upgrading the infrastructure would result in huge increase in vaccine cost

SAGE-Removal Costs Too MuchSAGE-Removal Costs Too Much

Page 100: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Lastly, the memo stated, “The actions required from WHO

in order to ensure continued availability of these vaccines

include the following: …Develop a strong

advocacy campaign to support ongoing use of

thimerosal.”

WHO-Support Use of ThimerosalWHO-Support Use of Thimerosal

Page 101: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

2004 Biochemical Link Revealed2004 Biochemical Link Revealed

April 2004 issue of Molecular Psychiatry, neuropharmacologist Richard Deth of Northeastern University in Boston and colleagues

described a biochemical pathway that may be the avenue by which

Thimerosal and other Mercury

contaminants cause neurodevelopmental

disorders such as autism.

Page 102: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,
Page 103: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Autism

“It's true, IT’S THIMEROSAL.” from the Simpsonwood meeting (Tom Verstraeten, M.D., CDC’s National Immunization Program presently employed by Glaxo-Welcome, vaccine company)

It is very likely that the mercury from thimerosal has contributed to the dramatic increase in both ADHD and autism as increases closely parallel increases in the mercury content of mandated childhood

vaccines greatly exceeding Federal safety guidelines

Genetic Risks

Autism incidence 1/10,000 in 1970

Autism incidence 1/160 in 2002

Thimerosal

Genetic

Risks

ThimerosalAutism

Aspartame

Page 104: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Autism

Autism incidence 1/10,000 in 1970

Autism incidence 1/160 in 2002

Genetic Risks

34 tons of mercury are used in 34 tons of mercury are used in dentistry annuallydentistry annually

Dental offices are the #1 contributors of mercury to wastewater

Page 105: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Each of us are obligated to vote with our feet, our wallets and our voices to claim the rights and powers that were taken from us while we slept - to end the unholy alliance between corporation & state that demonstrates over and over that it will poison all of us to make a buck.

Page 106: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

Corruption, Deception and DepravityMany within our government are loyal public servants dedicated to their mission of protecting the United States and serving its people no matter in what agency they serve. Those in lower ranking positions don't know what happens in the higher levels of authority, much less that some of their colleagues are rogue agents carrying out the biding of their nefarious handlers.

Corruption, Deception and DepravityCorruption, Deception and Depravity

Page 107: Thimerosal and Aspartame as cofactors in the Autism Epidemic Kenneth Stoller, MD, FAAP President, International Hyperbaric Medical Assoc. Medical Director,

The chemicals we ingest may affect more than our own health. They affect the health and vitality of future generations. The danger is that many of these chemicals may not harm us but will do silent violence to our children. Senator Abraham S. Ribicoff (l971)

The chemicals we ingest may affect more than our own health. They affect the health and vitality of future generations. The danger is that many of these chemicals may not harm us but will do silent violence to our children. Senator Abraham S. Ribicoff (l971)