Thermo Scientific CEDIA Cyclosporine Plus Immunoassay.pdfThermo Scientific CEDIA Cyclosporine Plus...
Transcript of Thermo Scientific CEDIA Cyclosporine Plus Immunoassay.pdfThermo Scientific CEDIA Cyclosporine Plus...
Thermo ScientificCEDIA Cyclosporine Plus Immunoassay
Accurate, efficient, and workflow convenience are synonymous with the Thermo Scientific CEDIA Cyclosporine Plus
Immunosuppressant assay. Using the CEDIA® technology, this Immunoassays offers optimal low end sensitivity and excellent
correlation with the “Gold Standard” HPLC/LCMS.
The CEDIA Cyclosporine Plus assay offers 2 point linear calibration and has applications for a variety of chemistry analyzers. No sample extraction and liquid, ready-to-use
calibrator provide time-saving convenience.
Part of Thermo Fisher Scientific
Thermo ScientificCEDIA Cyclosporine Plus Immunoassay
© 2011 Thermo Fisher Scientific Inc. All rights reserved. CEDIA is a registered trademark of Roche Diagnostics. All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries.
Dual Range ProtocolTwo assay ranges allow the best combination of low-end precision, quantitation of high samples and convenience.
Low-Range Protocol (Trough level)• Measures samples 25 to 450 ng/mL• Minimum detectable concentration is 25 ng/mL
High-Range Protocol (C2 level)• Measures samples from 450 to 2000 ng/mL• High range assay uses same reagents as low range assay
Low Range Assay Within Run Total
Sample N Mean SD %CV SD %CV
Low Pool 63 54.0 4.7 8.8 6.6 12.2
High Pool 63 434.7 6.7 1.6 19.4 4.5
High Range Assay Within Run Total
Sample N Mean SD %CV SD %CV
Low Pool 63 472 22.8 4.8 35.1 7.5
High Pool 63 1695 39.2 2.3 87.3 5.2
Assay Precision
Ordering Information: 1-800-232-3342
Low Assay Range Method ComparisonCEDIA® Cyclosporine Plus. All transplant types.
500
300
200
100
00 100 200 300 400
CsA
Plus
(ng/
mL)
HPLC-MS (ng/mL)
400
500
Slope: 0.99
Intercept: 7
r: 0.93
n: 359
High Assay Range Method ComparisonCEDIA® Cyclosporine Plus. All transplant types.
2000
1000
800
600
400
CsA
Plus
(ng/
mL)
HPLC-MS (ng/mL)
1200
Slope: 0.97
Intercept: 98.07
r: 0.97
n: 93
1800
1600
1400
20001000800600400 1200 180016001400
Sample Preparation = 1 minute
Add 100 μL sample Add 400 μL lysing reagent Vortex
Catalog # Product Description Kit Size (mL)
100147 Cyclosporine Plus Reagent Kit* 41, 19
100012 CsAPlus High Range Cal 2 x 4 ea
280-1 More Diagnostics Rap/Tac/CsA Control Level 1 4 x 4
280-2 More Diagnostics Rap/Tac/CsA Control Level 2 4 x 4
280-3 More Diagnostics Rap/Tac/CsA Control Level 3 4 x 4
100207 CsA Control High Level 4 6 x 2 ea, 2 x 8 diluent
100208 CsA Control High Level 5 6 x 2 ea, 2 x 8 diluent
* Low range calibrator included in the reagent kit.
Office Contact DetailsU.S.A.Phone: 800-232-3342Fax: 510-979-5002E-mail: [email protected]
Germany and European HeadquartersPhone: (+49) 0851 / 886 89 0E-mail: [email protected]
UK and IrelandPhone: (+44) 01727 / 82 10 99E-mail: [email protected]
Spain and PortugalPhone: (+34) 93 / 589 83 38E-mail: [email protected]
Belgium, Netherlands and LuxembourgPhone: (+31) 34 156 07 44E-mail: [email protected]
FrancePhone: (+33) 04 / 72 89 44 00E-mail: [email protected]
Nordic RegionPhone: (+46) 571 32140E-Mail: [email protected]
SwitzerlandPhone: (+41) 26 663 86 62E-mail: [email protected]
Australia and Asia PacificPhone: (+61) (2) 9649 9599E-mail: [email protected]
CanadaPhone: (+1) 905 286 4290E-mail: [email protected]
www.thermoscientific.com/diagnostics
2011 01-1