THE UNITED STATES The Economic Burden of Chronic Disease on

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The Economic Burden of Chronic Disease on THE UNITED STATES 2006 Population 298,816,954 Current Toll on The United States TODAY Over 162 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mental disorders, and pulmonary conditions — were reported in The United States in 2003. These conditions shorten lives, reduce quality of life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalence of the seven common chronic diseases. Lost Productivity 79% Treatment Expenditures 21% Treatment Expenditures: $277 Lost Productivity: $1,047 Total Costs: $1,324 Economic Impact in The United States 2003 (Annual Costs in Billions) From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007. Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org. Figures may not sum due to rounding. Cancers: 10,555,000 (3.7%) Diabetes: 13,729,000 (4.9%) Heart Disease: 19,145,000 (6.8%) Hypertension: 36,761,000 (13.0%) Stroke: 2,425,000 (0.9%) Mental Disorders: 30,338,000 (10.7%) Pulmonary Conditions: 49,206,000 (17.4%) * As % of non-institutionalized population. Number of treated cases based on patient self-reported data from 2003 MEPS. Excludes untreated and undiagnosed cases. Reported Cases in The United States, 2003 (and as % of population*) Top Quartile Second Third Bottom Quartile Milken Institute State Chronic Disease Index States in the top quartile have the lowest rates of seven common chronic diseases. And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — without even taking into consideration the many secondary health problems they cause — totaled $277 billion in 2003. These conditions also reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days (absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivity resulted in an annual economic loss in The United States of over $1 trillion in 2003.

Transcript of THE UNITED STATES The Economic Burden of Chronic Disease on

Page 1: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on THE UNITED STATES

2006 Population298,816,954

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Current Toll on The United States TODAYOver 162 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in The United States in 2003. These conditions shorten lives, reducequality of life, and create considerable burden for caregivers. The following map shows how states compare based on theprevalence of the seven common chronic diseases.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $277

Lost Productivity: $1,047

Total Costs: $1,324

Economic Impact in The United States2003 (Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 10,555,000 (3.7%)

Diabetes: 13,729,000 (4.9%)

HeartDisease: 19,145,000 (6.8%)

Hypertension: 36,761,000 (13.0%)

Stroke: 2,425,000 (0.9%)

MentalDisorders: 30,338,000 (10.7%)

PulmonaryConditions: 49,206,000 (17.4%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in The United States, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $277 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in The United States of over $1 trillion in 2003.

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The Economic Burden of Chronic Disease on The United States (continued)

0 10,000 20,000 30,000 40,000 50,000 60,000 70,000 80,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

40,910

17,662

41,577

18,201

55,517

14,122

5,763

9,354

9,561

9,078

2,538 / 589

2,791

3,060

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices— Chronic Disease in The United States TOMORROWOn our current path, The United States will experience a dramatic increase in chronic disease in the next 20 years. But thereis an alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid40.2 million cases of chronic conditions in 2023.

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$1,324

$2,192

$297

$3,030

$1,123

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in the United States sharply, by 27% ($1.1 trillion) in 2023. $905 billion of this would come from gains in productivity,and $218 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $5.7 trillion to the nation’s economic output, aboost of 18%.

GDP in 2050, Current Path: $32,229

GDP in 2050, Alternative Path: $37,898

Potential Gain in GDP: $5,668 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$790 $3,363 $4,153

AlternativePath

$572 $2,458 $3,030

CostsAvoided

$218(28%)

$905(27%)

$1,123(27%)

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The Economic Burden of Chronic Disease on ALABAMA

2006 Population4,599,030

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Current Toll on Alabama TODAYOver 2.9 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Alabama in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $4.7

Lost Productivity: $18.6

Total Costs: $23.3

Economic Impact in Alabama 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 167,000 (3.8%)

Diabetes: 245,000 (5.6%)

HeartDisease: 378,000 (8.6%)

Hypertension: 737,000 (16.8%)

Stroke: 46,000 (1.0%)

MentalDisorders: 485,000 (11.1%)

PulmonaryConditions: 854,000 (19.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Alabama, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $4.7 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Alabama of $18.6 billion in 2003.

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The Economic Burden of Chronic Disease on Alabama (continued)

0 200 400 600 800 1,000 1,200

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

589

327

762

292

913

209

82

173

176

149

44 10

45

45

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Alabama TOMORROWOn our current path, Alabama will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 681,000cases of chronic conditions in 2023.

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$23.3

$37.2

$5.0

$48.8

$18.0Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Alabama sharply, by 27% ($18 billion) in 2023. $14.7 billion of this would come from gains in productivity, and$3.4 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $55 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $311

GDP in 2050, Alternative Path: $365

Potential Gain in GDP: $55 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$12.1 $54.7 $66.8

AlternativePath

$8.7 $40.0 $48.8

CostsAvoided

$3.4(28%)

$14.7(27%)

$18.0(27%)

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The Economic Burden of Chronic Disease on ALASKA

2006 Population670,053

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Current Toll on Alaska TODAYNearly 300,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Alaska in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 20,000 (3.2%)

Diabetes: 20,000 (3.2%)

HeartDisease: 17,000 (2.7%)

Hypertension: 60,000 (9.5%)

Stroke: 3,000 (0.5%)

MentalDisorders: 74,000 (11.7%)

PulmonaryConditions: 105,000 (16.7%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Alaska, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

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And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Alaska of $1.9 billion in 2003.

Lost Productivity74%

Treatment Expenditures26%

Treatment Expenditures: $0.6

Lost Productivity: $1.9

Total Costs: $2.5

Economic Impact in Alaska 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

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The Economic Burden of Chronic Disease on Alaska (continued)

0 30 60 90 120 150

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

116

25

70

28

126

33

17

14

16

20

4 1

5

7

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Alaska TOMORROWOn our current path, Alaska will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid79,000 cases of chronic conditions in 2023.

0

2

4

6

8

10

Billi

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$2.5

$4.7

$0.6

$7.0

$2.6Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Alaska sharply, by 27% ($2.6 billion) in 2023. $1.9 billion of this would come from gains in productivity, and$0.7 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $21 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $120

GDP in 2050, Alternative Path: $141

Potential Gain in GDP: $21 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$2.6 $7.0 $9.6

AlternativePath

$1.9 $5.1 $7.0

CostsAvoided

$0.7(28%)

$1.9(27%)

$2.6(27%)

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The Economic Burden of Chronic Disease on ARIZONA

2006 Population6,166,318

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Current Toll on Arizona TODAYNearly 2.8 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Arizona in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalence ofthe seven common chronic diseases.

Cancers: 161,000 (2.9%)

Diabetes: 217,000 (4.0%)

HeartDisease: 294,000 (5.4%)

Hypertension: 559,000 (10.2%)

Stroke: 33,000 (0.6%)

MentalDisorders: 683,000 (12.5%)

PulmonaryConditions: 824,000 (15.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Arizona, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

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And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $4.2 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Arizona of $17.4 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $4.2

Lost Productivity: $17.4

Total Costs: $21.5

Economic Impact in Arizona 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

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The Economic Burden of Chronic Disease on Arizona (continued)

0 300 600 900 1,200 1,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,290

401

910

440

1,214

292

181

212

210

198

51 12

68

63

0

Reported Cases (Thousands)

BCases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Arizona TOMORROWOn our current path, Arizona will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 944,000cases of chronic conditions in 2023.

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$21.5

$43.0

$5.6

$71.8

$25.6

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Arizona sharply, by 26% ($25.6 billion) in 2023. $20.4 billion of this would come from gains in productivity,and $5.2 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $183 billion to the state’s economic output, a boostof 17%.

GDP in 2050, Current Path: $1,063

GDP in 2050, Alternative Path: $1,247

Potential Gain in GDP: $183 (17%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$18.6 $78.8 $97.4

AlternativePath

$13.4 $58.4 $71.8

CostsAvoided

$5.2(28%)

$20.4(26%)

$25.6(26%)

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The Economic Burden of Chronic Disease on ARKANSAS

2006 Population2,810,872

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Current Toll on Arkansas TODAYOver 1.7 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Arkansas in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 125,000 (4.7%)

Diabetes: 126,000 (4.8%)

HeartDisease: 224,000 (8.5%)

Hypertension: 411,000 (15.5%)

Stroke: 32,000 (1.2%)

MentalDisorders: 278,000 (10.5%)

PulmonaryConditions: 503,000 (19.0%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Arkansas, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $2.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Arkansas of $11.3 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $2.6

Lost Productivity: $11.3

Total Costs: $13.9

Economic Impact in Arkansas 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

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The Economic Burden of Chronic Disease on Arkansas (continued)

0 100 200 300 400 500 600 700 800

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

356

188

445

156

563

161

50

99

103

92

31 7

24

36

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Arkansas TOMORROWOn our current path, Arkansas will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 410,000cases of chronic conditions in 2023.

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$13.9

$22.8

$3.2

$30.3

$11.7Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Arkansas sharply, by 28% ($11.7 billion) in 2023. $9.6 billion of this would come from gains in productivity, and$2.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $33 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $186

GDP in 2050, Alternative Path: $219

Potential Gain in GDP: $33 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$7.3 $34.7 $42.1

AlternativePath

$5.2 $25.1 $30.3

CostsAvoided

$2.1(29%)

$9.6(28%)

$11.7(28%)

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The Economic Burden of Chronic Disease on CALIFORNIA

2006 Population36,457,549

Current Toll on California TODAYOver 16.3 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in California in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 1,155,000 (3.3%)

Diabetes: 1,573,000 (4.5%)

HeartDisease: 1,860,000 (5.4%)

Hypertension: 3,660,000 (10.6%)

Stroke: 241,000 (0.7%)

MentalDisorders: 2,534,000 (7.3%)

PulmonaryConditions: 5,301,000 (15.3%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in California, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $26.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in California of $106.2 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $26.9

Lost Productivity: $106.2

Total Costs: $133.0

Economic Impact in California 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

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The Economic Burden of Chronic Disease on California (continued)

0 1,000 2,000 3,000 4,000 5,000 6,000 7,000 8,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

3,579

1,909

4,397

2,242

6,001

1,584

505

1,011

1,011

981

275 64

344

343

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in California TOMORROWOn our current path, California will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 4.3 millioncases of chronic conditions in 2023.

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$133

$224

$30

$314

$117

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in California sharply, by 27% ($117 billion) in 2023. $98 billion of this would come from gains in productivity,and $19 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $908 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $5,188

GDP in 2050, Alternative Path: $6,096

Potential Gain in GDP: $908 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$72 $359 $431

AlternativePath

$53 $261 $314

CostsAvoided

$19(26%)

$98(27%)

$117(27%)

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The Economic Burden of Chronic Disease on COLORADO

2006 Population4,753,377

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Current Toll on Colorado TODAYOver 2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Colorado in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $3.4

Lost Productivity: $13.1

Total Costs: $16.5

Economic Impact in Colorado 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 148,000 (3.3%)

Diabetes: 132,000 (3.0%)

HeartDisease: 176,000 (4.0%)

Hypertension: 397,000 (8.9%)

Stroke: 25,000 (0.6%)

MentalDisorders: 500,000 (11.2%)

PulmonaryConditions: 672,000 (15.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Colorado, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $3.4 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Colorado of $13.1 billion in 2003.

Page 14: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Colorado (continued)

0 200 400 600 800 1,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

696

177

445

178

750

202

99

94

102

123

29 6

27

44

0

Reported Cases (Thousands)

BCases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Colorado TOMORROWOn our current path, Colorado will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 495,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

Billi

ons

ofD

olla

rs

2003 2013 2023

$16.5

$28.2

$3.8

$39.9

$14.7Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Colorado sharply, by 27% ($14.7 billion) in 2023. $11.6 billion of this would come from gains in productivity,and $3.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $91 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $516

GDP in 2050, Alternative Path: $607

Potential Gain in GDP: $91 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$11.3 $43.3 $54.6

AlternativePath

$8.2 $31.7 $39.9

CostsAvoided

$3.1(28%)

$11.6(27%)

$14.7(27%)

Page 15: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on CONNECTICUT

2006 Population3,504,809

L

Current Toll on Connecticut TODAYNearly 2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Connecticut in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 136,000 (4.0%)

Diabetes: 147,000 (4.4%)

HeartDisease: 224,000 (6.6%)

Hypertension: 434,000 (12.9%)

Stroke: 30,000 (0.9%)

MentalDisorders: 408,000 (12.1%)

PulmonaryConditions: 611,000 (18.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Connecticut, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $3.3 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Connecticut of $12.9 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $3.3

Lost Productivity: $12.9

Total Costs: $16.2

Economic Impact in Connecticut 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 16: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Connecticut (continued)

0 100 200 300 400 500 600 700 800

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

489

186

437

172

620

162

69

98

101

102

28 6

26

35

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices — Chronic Disease in Connecticut TOMORROWOn our current path, Connecticut will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 437,000cases of chronic conditions in 2023.

0

10

20

30

40

50

Billi

ons

ofD

olla

rs

2003 2013 2023

$16.2

$25.3

$3.4

$32.6

$11.9Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Connecticut sharply, by 27% ($11.9 billion) in 2023. $9.9 billion of this would come from gains in productivity,and $1.9 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $63 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $356

GDP in 2050, Alternative Path: $418

Potential Gain in GDP: $63 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$7.6 $36.9 $44.5

AlternativePath

$5.7 $26.9 $32.6

CostsAvoided

$1.9(25%)

$9.9(27%)

$11.9(27%)

Page 17: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on DELAWARE

2006 Population853,476

L

Current Toll on Delaware TODAYNearly 480,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Delaware in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 34,000 (4.3%)

Diabetes: 39,000 (4.9%)

HeartDisease: 58,000 (7.3%)

Hypertension: 112,000 (14.1%)

Stroke: 6,000 (0.8%)

MentalDisorders: 74,000 (9.3%)

PulmonaryConditions: 155,000 (19.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Delaware, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom QuartileMilken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Delaware of $3.1 billion in 2003.

Lost Productivity77%

Treatment Expenditures23%

Treatment Expenditures: $0.9

Lost Productivity: $3.1

Total Costs: $4.0

Economic Impact in Delaware 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 18: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Delaware (continued)

0 50 100 150 200 250

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

103

61

136

57

177

47

14

32

31

29

7 2

8

10

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices — Chronic Disease in Delaware TOMORROWOn our current path, Delaware will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 127,000cases of chronic conditions in 2023.

0

3

6

9

12

15

Billi

ons

ofD

olla

rs

2003 2013 2023

$4.0

$7.1

$1.0

$9.9

$3.9Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Delaware sharply, by 28% ($3.9 billion) in 2023. $2.9 billion of this would come from gains in productivity,and $1.0 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $25 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $142

GDP in 2050, Alternative Path: $167

Potential Gain in GDP: $25 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$3.2 $10.6 $13.8

AlternativePath

$2.3 $7.7 $9.9

CostsAvoided

$1.0(30%)

$2.9(28%)

$3.9(28%)

Page 19: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on FLORIDA

2006 Population18,089,888

L

Current Toll on Florida TODAYOver 10 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Florida in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 657,000 (4.0%)

Diabetes: 905,000 (5.4%)

HeartDisease: 1,384,000 (8.3%)

Hypertension: 2,463,000 (14.8%)

Stroke: 151,000 (0.9%)

MentalDisorders: 2,182,000 (13.1%)

PulmonaryConditions: 2,622,000 (15.8%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Florida, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $17.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Florida of $68.7 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $17.6

Lost Productivity: $68.7

Total Costs: $86.3

Economic Impact in Florida 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 20: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Florida (continued)

0 1,000 2,000 3,000 4,000 5,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

3,615

1,561

3,577

1,540

3,530

1,055

509

827

823

577

198 46

236

229

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Florida TOMORROWOn our current path, Florida will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 3.2 millioncases of chronic conditions in 2023.

0

50

100

150

200

250

300

350

Billi

ons

ofD

olla

rs

2003 2013 2023

$86

$158

$21

$246

$91

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Florida sharply, by 27% ($91 billion) in 2023. $73 billion of this would come from gains in productivity, and$18 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $531 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $3,009

GDP in 2050, Alternative Path: $3,540

Potential Gain in GDP: $531 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$64 $274 $337

AlternativePath

$46 $201 $246

CostsAvoided

$18(28%)

$73(27%)

$91(27%)

Page 21: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on GEORGIA

2006 Population9,363,941

L

Current Toll on Georgia TODAYOver 5 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Georgia in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 345,000 (4.1%)

Diabetes: 427,000 (5.1%)

HeartDisease: 494,000 (5.9%)

Hypertension: 1,212,000 (14.4%)

Stroke: 66,000 (0.8%)

MentalDisorders: 930,000 (11.0%)

PulmonaryConditions: 1,549,000 (18.4%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Georgia, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $7.1 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Georgia of $32.8 billion in 2003.

Lost Productivity82%

Treatment Expenditures18%

Treatment Expenditures: $7.1

Lost Productivity: $32.8

Total Costs: $39.9

Economic Impact in Georgia 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 22: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Georgia (continued)

0 500 1,000 1,500 2,000 2,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,377

503

1,478

600

1,913

512

194

266

340

312

75 17

92

111

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Georgia TOMORROWOn our current path, Georgia will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 1.3 millioncases of chronic conditions in 2023.

0

30

60

90

120

150

Billi

ons

ofD

olla

rs

2003 2013 2023

$40

$70

$9

$101

$37Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Georgia sharply, by 27% ($37 billion) in 2023. $31 billion of this would come from gains in productivity, and$6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $177 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $1,007

GDP in 2050, Alternative Path: $1,183

Potential Gain in GDP: $177 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$22 $115 $138

AlternativePath

$16 $84 $101

CostsAvoided

$6(27%)

$31(27%)

$37(27%)

Page 23: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on HAWAII

2006 Population1,285,498

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Current Toll on Hawaii TODAYOver 560,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Hawaii in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $1.1

Lost Productivity: $3.9

Total Costs: $4.9

Economic Impact in Hawaii 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 38,000 (3.1%)

Diabetes: 58,000 (4.7%)

HeartDisease: 66,000 (5.4%)

Hypertension: 128,000 (10.5%)

Stroke: 10,000 (0.8%)

MentalDisorders: 139,000 (11.4%)

PulmonaryConditions: 124,000 (10.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Hawaii, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.1 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Hawaii of $3.9 billion in 2003.

Page 24: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Hawaii (continued)

0 50 100 150 200 250

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

183

62

134

75

136

49

26

33

31

22

11 3

11

10

0

Reported Cases (Thousands)

BCases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Hawaii TOMORROWOn our current path, Hawaii will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 136,000cases of chronic conditions in 2023.

0

3

6

9

12

15

Billi

ons

ofD

olla

rs

2003 2013 2023

$4.9

$8.1

$1.1

$10.8

$3.9

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Hawaii sharply, by 26% ($3.9 billion) in 2023. $3.2 billion of this would come from gains in productivity, and $0.7billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $27 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $156

GDP in 2050, Alternative Path: $184

Potential Gain in GDP: $27 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$2.7 $12 $14.7

AlternativePath

$2.0 $8.8 $10.8

CostsAvoided

$0.7(26%)

$3.2(27%)

$3.9(26%)

Page 25: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on IDAHO

2006 Population1,466,465

L

Current Toll on Idaho TODAYNearly 650,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Idaho in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalence ofthe seven common chronic diseases.

Cancers: 46,000 (3.5%)

Diabetes: 53,000 (4.0%)

HeartDisease: 69,000 (5.2%)

Hypertension: 139,000 (10.4%)

Stroke: 10,000 (0.8%)

MentalDisorders: 136,000 (10.2%)

PulmonaryConditions: 192,000 (14.4%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Idaho, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Idaho of $4.3 billion in 2003.

Lost Productivity82%

Treatment Expenditures18%

Treatment Expenditures: $0.9

Lost Productivity: $4.3

Total Costs: $5.2

Economic Impact in Idaho 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 26: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Idaho (continued)

0 50 100 150 200 250 300

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

206

77

183

93

241

67

29

41

42

39

13 3

14

15

0

Reported Cases (Thousands)

BCases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Idaho TOMORROWOn our current path, Idaho will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 183,000cases of chronic conditions in 2023.

0

5

10

15

20

Billi

ons

ofD

olla

rs

2003 2013 2023

$5.2

$9.5

$1.3

$14.2

$5.3

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Idaho sharply, by 27% ($5.3 billion) in 2023. $4.2 billion of this would come from gains in productivity, and$1.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $27 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $151

GDP in 2050, Alternative Path: $177

Potential Gain in GDP: $27 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$3.7 $15.8 $19.5

AlternativePath

$2.6 $11.5 $14.2

CostsAvoided

$1.1(29%)

$4.2(27%)

$5.3(27%)

Page 27: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on ILLINOIS

2006 Population12,831,970

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Current Toll on Illinois TODAYOver 6.7 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Illinois in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 445,000 (3.6%)

Diabetes: 540,000 (4.4%)

HeartDisease: 851,000 (6.9%)

Hypertension: 1,570,000 (12.7%)

Stroke: 113,000 (0.9%)

MentalDisorders: 1,143,000 (9.3%)

PulmonaryConditions: 2,116,000 (17.2%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Illinois, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $12.5 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Illinois of $43.6 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $12.5

Lost Productivity: $43.6

Total Costs: $56.1

Economic Impact in Illinois 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 28: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Illinois (continued)

0 500 1,000 1,500 2,000 2,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,351

668

1,558

611

2,123

518

190

353

358

347

101 23

93

112

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Illinois TOMORROWOn our current path, Illinois will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid nearly1.5 million cases of chronic conditions in 2023.

0

50

100

150

200

Billi

ons

ofD

olla

rs

2003 2013 2023

$56

$86

$12

$110

$41

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Illinois sharply, by 27% ($41 billion) in 2023. $33 billion of this would come from gains in productivity,and $8 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $188 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $1,072

GDP in 2050, Alternative Path: $1,261

Potential Gain in GDP: $188 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$29 $122 $150

AlternativePath

$21 $89 $110

CostsAvoided

$8(27%)

$33(27%)

$41(27%)

Page 29: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on INDIANA

2006 Population6,313,520

L

Current Toll on Indiana TODAYOver 3.6 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Indiana in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 208,000 (3.5%)

Diabetes: 283,000 (4.7%)

HeartDisease: 441,000 (7.3%)

Hypertension: 862,000 (14.3%)

Stroke: 59,000 (1.0%)

MentalDisorders: 624,000 (10.4%)

PulmonaryConditions: 1,135,000 (18.9%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Indiana, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $6.7 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Indiana of $22.7 billion in 2003.

Lost Productivity77%

Treatment Expenditures23%

Treatment Expenditures: $6.7

Lost Productivity: $22.7

Total Costs: $29.4

Economic Impact in Indiana 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 30: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Indiana (continued)

0 300 600 900 1,200 1,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

755

352

873

329

1,205

253

106

186

200

197

54 13

50

55

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Indiana TOMORROWOn our current path, Indiana will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 808,000cases of chronic conditions in 2023.

0

20

40

60

80

100

Billi

ons

ofD

olla

rs

2003 2013 2023

$29.4

$46.1

$6.2

$59.9

$21.9Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Indiana sharply, by 27% ($21.9 billion) in 2023. $17.3 billion of this would come from gains in productivity,and $4.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $82 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $469

GDP in 2050, Alternative Path: $552

Potential Gain in GDP: $82 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$16.7 $65.0 $81.7

AlternativePath

$12.1 $47.7 $59.9

CostsAvoided

$4.6(27%)

$17.3(27%)

$21.9(27%)

Page 31: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on IOWA

2006 Population2,982,085

L

Current Toll on Iowa TODAYNearly 1.6 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Iowa in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalence of theseven common chronic diseases.

Cancers: 101,000 (3.6%)

Diabetes: 115,000 (4.0%)

HeartDisease: 224,000 (7.9%)

Hypertension: 380,000 (13.4%)

Stroke: 34,000 (1.2%)

MentalDisorders: 319,000 (11.2%)

PulmonaryConditions: 412,000 (14.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Iowa, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $2.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Iowa of $10.5 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $2.9

Lost Productivity: $10.5

Total Costs: $13.4

Economic Impact in Iowa 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 32: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Iowa (continued)

0 100 200 300 400 500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

366

175

371

137

420

116

52

92

86

68

31 7

22

25

0

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Iowa TOMORROWOn our current path, Iowa will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 351,000cases of chronic conditions in 2023.

0

5

10

15

20

25

30

35

40

Billi

ons

ofD

olla

rs

2003 2013 2023

$13.4

$20.8

$2.8

$26.5

$9.9Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Iowa sharply, by 27% ($9.9 billion) in 2023. $7.8 billion of this would come from gains in productivity, and$2.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $35 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $200

GDP in 2050, Alternative Path: $236

Potential Gain in GDP: $35 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$7.4 $29.0 $36.4

AlternativePath

$5.3 $21.2 $26.5

CostsAvoided

$2.1(28%)

$7.8(27%)

$9.9(27%)

Page 33: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on KANSAS

2006 Population2,764,075

L

Current Toll on Kansas TODAYAlmost 1.5 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Kansas in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $2.6

Lost Productivity: $9.3

Total Costs: $12.0

Economic Impact in Kansas 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 87,000 (3.3%)

Diabetes: 96,000 (3.6%)

HeartDisease: 185,000 (7.0%)

Hypertension: 327,000 (12.4%)

Stroke: 29,000 (1.1%)

MentalDisorders: 308,000 (11.7%)

PulmonaryConditions: 462,000 (17.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Kansas, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $2.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Kansas of $9.3 billion in 2003.

Page 34: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Kansas (continued)

0 100 200 300 400 500 600

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

372

153

334

115

477

105

52

81

77

78

27 7

17

23

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Kansas TOMORROWOn our current path, Kansas will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 335,000cases of chronic conditions in 2023.

0

5

10

15

20

25

30

35

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$12.0$18.9

$2.5

$24.7

$9.1

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Kansas sharply, by 27% ($9.1 billion) in 2023. $7.2 billion of this would come from gains in productivity,and $1.9 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $39 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $224

GDP in 2050, Alternative Path: $263

Potential Gain in GDP: $39 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$6.8 $26.9 $33.8

AlternativePath

$4.9 $19.8 $24.7

CostsAvoided

$1.9(28%)

$7.2(27%)

$9.1(27%)

Page 35: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on KENTUCKY

2006 Population4,206,074

L

Current Toll on Kentucky TODAYOver 2.7 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Kentucky in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 173,000 (4.3%)

Diabetes: 219,000 (5.5%)

HeartDisease: 325,000 (8.1%)

Hypertension: 607,000 (15.2%)

Stroke: 37,000 (0.9%)

MentalDisorders: 378,000 (9.4%)

PulmonaryConditions: 1,020,000 (25.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Kentucky, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $4.7 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Kentucky of $16.9 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $4.7

Lost Productivity: $16.9

Total Costs: $21.6

Economic Impact in Kentucky 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 36: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Kentucky (continued)

0 300 600 900 1,200 1,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

466

277

630

267

1,119

220

66

147

145

184

36 8

41

48

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Kentucky TOMORROWOn our current path, Kentucky will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 638,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

70

80

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$21.6

$35.1

$4.9

$46.6

$17.8

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Kentucky sharply, by 28% ($17.8 billion) in 2023. $13.8 billion of this would come from gains in productivity, and$4.0 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $53 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $301

GDP in 2050, Alternative Path: $353

Potential Gain in GDP: $53 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$13.9 $50.5 $64.4

AlternativePath

$9.9 $36.7 $46.6

CostsAvoided

$4.0(29%)

$13.8(27%)

$17.8(28%)

Page 37: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on LOUISIANA

2006 Population4,287,768

L

Current Toll on Louisiana TODAYOver 2.5 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Louisiana in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 183,000 (4.2%)

Diabetes: 239,000 (5.5%)

HeartDisease: 332,000 (7.6%)

Hypertension: 644,000 (14.8%)

Stroke: 39,000 (0.9%)

MentalDisorders: 445,000 (10.2%)

PulmonaryConditions: 704,000 (16.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Louisiana, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $4.5 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Louisiana of $17.4 billion in 2003.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $4.5

Lost Productivity: $17.4

Total Costs: $22.0

Economic Impact in Louisiana 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 38: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Louisiana (continued)

0 200 400 600 800 1,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

543

297

669

284

744

230

77

157

154

121

38 8

44

50

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Louisiana TOMORROWOn our current path, Louisiana will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 612,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

70

80

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$22.0

$35.3

$4.9

$45.6

$17.3

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Louisiana sharply, by 28% ($17.3 billion) in 2023. $14.3 billion of this would come from gains in productivity,and $3.0 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $62 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $356

GDP in 2050, Alternative Path: $418

Potential Gain in GDP: $62 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$11.0 $52.0 $63.0

AlternativePath

$8.0 $37.7 $45.6

CostsAvoided

$3.0(27%)

$14.3(28%)

$17.3(28%)

Page 39: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MAINE

2006 Population1,321,574

L

Current Toll on Maine TODAYOver 844,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Maine in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 53,000 (4.2%)

Diabetes: 69,000 (5.4%)

HeartDisease: 83,000 (6.5%)

Hypertension: 175,000 (13.8%)

Stroke: 13,000 (1.0%)

MentalDisorders: 177,000 (13.9%)

PulmonaryConditions: 274,000 (21.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Maine, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.4 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Maine of $5.3 billion in 2003.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $1.4

Lost Productivity: $5.3

Total Costs: $6.7

Economic Impact in Maine 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 40: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Maine (continued)

0 50 100 150 200 250 300 350 400

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

224

83

193

104

306

69

32

44

45

50

14 3

15

15

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Maine TOMORROWOn our current path, Maine will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 204,000cases of chronic conditions in 2023.

0

5

10

15

20

25

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$6.7

$11.5

$1.5

$15.8

$5.8

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Maine sharply, by 27% ($5.8 billion) in 2023. $4.5 billion of this would come from gains in productivity, and $1.3 bil-lion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $19 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $111

GDP in 2050, Alternative Path: $130

Potential Gain in GDP: $19 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$4.6 $17.0 $21.6

AlternativePath

$3.3 $12.5 $15.8

CostsAvoided

$1.3(28%)

$4.5(26%)

$5.8(27%)

Page 41: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MARYLAND

2006 Population5,615,727

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Current Toll on Maryland TODAYOver 3.2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Maryland in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 227,000 (4.2%)

Diabetes: 242,000 (4.5%)

HeartDisease: 350,000 (6.5%)

Hypertension: 682,000 (12.7%)

Stroke: 42,000 (0.8%)

MentalDisorders: 582,000 (10.8%)

PulmonaryConditions: 1,088,000 (20.3%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Maryland, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $5.2 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Maryland of $20.5 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $5.2

Lost Productivity: $20.5

Total Costs: $25.7

Economic Impact in Maryland 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 42: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Maryland (continued)

0 300 600 900 1,200 1,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

796

321

754

297

1,272

313

112

170

174

209

43 10

46

68

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Maryland TOMORROWOn our current path, Maryland will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 787,000cases of chronic conditions in 2023.

0

20

40

60

80

100

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$25.7

$43.1

$6.0

$58.9

$22.2Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Maryland sharply, by 27% ($22.2 billion) in 2023. $18.1 billion of this would come from gains in productivity, and$4.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $112 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $637

GDP in 2050, Alternative Path: $749

Potential Gain in GDP: $112 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$14.9 $66.2 $81.1

AlternativePath

$10.8 $48.1 $58.9

CostsAvoided

$4.1(27%)

$18.1(27%)

$22.2(27%)

Page 43: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MASSACHUSETTS

2006 Population6,437,193

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Current Toll on Massachusetts TODAYNearly 4.2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Massachusetts in 2003. These conditions shorten lives, reducequality of life, and create considerable burden for caregivers. The following map shows how states compare based on theprevalence of the seven common chronic diseases.

Lost Productivity76%

Treatment Expenditures24%

Treatment Expenditures: $8.1

Lost Productivity: $25.9

Total Costs: $34.0

Economic Impact in Massachusetts 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 257,000 (4.1%)

Diabetes: 285,000 (4.6%)

HeartDisease: 391,000 (6.3%)

Hypertension: 762,000 (12.3%)

Stroke: 56,000 (0.9%)

MentalDisorders: 1,089,000 (17.5%)

PulmonaryConditions: 1,342,000 (21.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Massachusetts, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $8.1 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Massachusetts of $25.9 billion in 2003.

Page 44: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Massachusetts (continued)

0 500 1,000 1,500 2,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,322

319

777

343

1,395

309

187

168

179

229

53 13

53

66

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Massachusetts TOMORROWOn our current path, Massachusetts will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 893,000cases of chronic conditions in 2023.

0

20

40

60

80

100

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$34.0

$53.2

$6.8

$70.7

$24.7

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs of diseasein Massachusetts sharply, by 26% ($24.7 billion) in 2023. $19.5 billion of this would come from gains in productivity, and$5.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $109 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $619

GDP in 2050, Alternative Path: $728

Potential Gain in GDP: $109 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$20.1 $75.3 $95.4

AlternativePath

$15.0 $55.8 $70.7

CostsAvoided

$5.1(26%)

$19.5(26%)

$24.7(26%)

Page 45: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MICHIGAN

2006 Population10,095,643

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Current Toll on Michigan TODAYNearly 6.2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Michigan in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 359,000 (3.7%)

Diabetes: 465,000 (4.7%)

HeartDisease: 742,000 (7.6%)

Hypertension: 1,391,000 (14.2%)

Stroke: 90,000 (0.9%)

MentalDisorders: 998,000 (10.2%)

PulmonaryConditions: 2,119,000 (21.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Michigan, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $10.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Michigan of $37.9 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $10.6

Lost Productivity: $37.9

Total Costs: $48.4

Economic Impact in Michigan 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 46: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Michigan (continued)

0 500 1,000 1,500 2,000 2,500 3,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,206

631

1,439

553

2,229

441

169

304

330

364

86 20

85

93

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Michigan TOMORROWOn our current path, Michigan will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 1.4 millioncases of chronic conditions in 2023.

0

30

60

90

120

150

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$48

$77

$10

$99

$36

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Michigan sharply, by 27% ($36 billion) in 2023. $30 billion of this would come from gains in productivity, and$7 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $146 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $828

GDP in 2050, Alternative Path: $973

Potential Gain in GDP: $146 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$25 $111 $135

AlternativePath

$18 $81 $99

CostsAvoided

$7(27%)

$30(27%)

$36(27%)

Page 47: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MINNESOTA

2006 Population5,167,101

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Current Toll on Minnesota TODAYOver 2.7 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Minnesota in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 175,000 (3.6%)

Diabetes: 163,000 (3.3%)

HeartDisease: 232,000 (4.7%)

Hypertension: 579,000 (11.8%)

Stroke: 42,000 (0.9%)

MentalDisorders: 750,000 (15.2%)

PulmonaryConditions: 778,000 (15.8%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Minnesota, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $5.3 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Minnesota of $17.5 billion in 2003.

Lost Productivity77%

Treatment Expenditures23%

Treatment Expenditures: $5.3

Lost Productivity: $17.5

Total Costs: $22.8

Economic Impact in Minnesota 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 48: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Minnesota (continued)

0 200 400 600 800 1,000 1,200

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,011

214

656

220

910

238

142

113

151

149

45 10

34

52

Reported Cases (Thousands)

BCases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Minnesota TOMORROWOn our current path, Minnesota will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 651,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

70

80

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$22.8

$38.6

$5.0

$54.5

$19.3

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Minnesota sharply, by 26% ($19.3 billion) in 2023. $14.8 billion of this would come from gains in productivity,and $4.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $101 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $575

GDP in 2050, Alternative Path: $676

Potential Gain in GDP: $101 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$16.8 $57.0 $73.8

AlternativePath

$12.2 $42.2 $54.5

CostsAvoided

$4.6(27%)

$14.8(26%)

$19.3(26%)

Page 49: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MISSISSIPPI

2006 Population2,910,540

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Current Toll on Mississippi TODAYOver 1.8 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Mississippi in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 127,000 (4.6%)

Diabetes: 199,000 (7.1%)

HeartDisease: 250,000 (9.0%)

Hypertension: 476,000 (17.1%)

Stroke: 27,000 (1.0%)

MentalDisorders: 240,000 (8.6%)

PulmonaryConditions: 503,000 (18.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Mississippi, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $2.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Mississippi of $12.3 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $2.9

Lost Productivity: $12.3

Total Costs: $15.2

Economic Impact in Mississippi 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 50: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Mississippi (continued)

0 100 200 300 400 500 600 700 800

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

293

223

515

250

543

162

41

118

119

89

26 6

39

35

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Mississippi TOMORROWOn our current path, Mississippi will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 446,000cases of chronic conditions in 2023.

0

10

20

30

40

50

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$15.2

$25.0

$3.5

$33.3

$13.0

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Mississippi sharply, by 28% ($13.0 billion) in 2023. $10.4 billion of this would come from gains in productivity,and $2.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $29 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $167

GDP in 2050, Alternative Path: $197

Potential Gain in GDP: $29 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$8.7 $37.5 $46.3

AlternativePath

$6.1 $27.1 $33.3

CostsAvoided

$2.6(30%)

$10.4(28%)

$13.0(28%)

Page 51: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MISSOURI

2006 Population5,842,713

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Current Toll on Missouri TODAYNearly 3.4 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Missouri in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 186,000 (3.4%)

Diabetes: 231,000 (4.2%)

HeartDisease: 468,000 (8.5%)

Hypertension: 810,000 (14.6%)

Stroke: 59,000 (1.1%)

MentalDisorders: 597,000 (10.8%)

PulmonaryConditions: 1,034,000 (18.7%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Missouri, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $7.1 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Missouri of $21.1 billion in 2003.

Lost Productivity75%

Treatment Expenditures25%

Treatment Expenditures: $7.1

Lost Productivity: $21.1

Total Costs: $28.2

Economic Impact in Missouri 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 52: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Missouri (continued)

0 300 600 900 1,200 1,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

738

388

842

275

1,134

235

104

206

194

185

55 13

42

51

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Missouri TOMORROWOn our current path, Missouri will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 794,000cases of chronic conditions in 2023.

0

20

40

60

80

100

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$28.2

$44.9

$6.1

$59.1

$22.1

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Missouri sharply, by 27% ($22.1 billion) in 2023. $16.7 billion of this would come from gains in productivity, and$5.5 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $85 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $486

GDP in 2050, Alternative Path: $571

Potential Gain in GDP: $85 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$19.0 $62.2 $81.2

AlternativePath

$13.5 $45.6 $59.1

CostsAvoided

$5.5(29%)

$16.7(27%)

$22.1(27%)

Page 53: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on MONTANA

2006 Population944,632

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Current Toll on Montana TODAYOver 480,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Montana in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $0.9

Lost Productivity: $3.1

Total Costs: $4.0

Economic Impact in Montana 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 31,000 (3.5%)

Diabetes: 31,000 (3.5%)

HeartDisease: 54,000 (6.1%)

Hypertension: 86,000 (9.6%)

Stroke: 8,000 (0.9%)

MentalDisorders: 141,000 (15.8%)

PulmonaryConditions: 129,000 (14.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Montana, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Montana of $3.1 billion in 2003.

Page 54: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Montana (continued)

0 50 100 150 200 250

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

189

58

99

50

145

42

26

31

23

24

9 2

7

9

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Montana TOMORROWOn our current path, Montana will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 123,000cases of chronic conditions in 2023.

0

3

6

9

12

15

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$4.0

$6.9

$0.9

$9.7

$3.6

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Montana sharply, by 27% ($3.6 billion) in 2023. $2.8 billion of this would come from gains in productivity, and$0.8 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $14 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $77

GDP in 2050, Alternative Path: $91

Potential Gain in GDP: $14 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$2.9 $10.4 $13.3

AlternativePath

$2.1 $7.7 $9.7

CostsAvoided

$0.8(28%)

$2.8(26%)

$3.6(27%)

Page 55: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NEBRASKA

2006 Population1,768,331

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Current Toll on Nebraska TODAYOver 950,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Nebraska in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 58,000 (3.4%)

Diabetes: 65,000 (3.9%)

HeartDisease: 113,000 (6.7%)

Hypertension: 210,000 (12.4%)

Stroke: 18,000 (1.1%)

MentalDisorders: 208,000 (12.3%)

PulmonaryConditions: 279,000 (16.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Nebraska, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Nebraska of $6.1 billion in 2003.

Lost Productivity76%

Treatment Expenditures24%

Treatment Expenditures: $1.9

Lost Productivity: $6.1

Total Costs: $8.0

Economic Impact in Nebraska 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 56: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Nebraska (continued)

0 50 100 150 200 250 300 350

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

245

90

206

76

283

68

34

47

48

46

17 4

12

15

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Nebraska TOMORROWOn our current path, Nebraska will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 206,000cases of chronic conditions in 2023.

0

5

10

15

20

25

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$8.0

$12.4

$1.7

$16.2

$6.0

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Nebraska sharply, by 27% ($6.0 billion) in 2023. $4.5 billion of this would come from gains in productivity, and$1.5 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $24 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $139

GDP in 2050, Alternative Path: $163

Potential Gain in GDP: $24 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$5.2 $17.0 $22.3

AlternativePath

$3.7 $12.5 $16.2

CostsAvoided

$1.5(29%)

$4.5(26%)

$6.0(27%)

Page 57: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NEVADA

2006 Population2,495,529

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Current Toll on Nevada TODAYOver 1.1 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Nevada in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 80,000 (3.6%)

Diabetes: 87,000 (3.9%)

HeartDisease: 124,000 (5.6%)

Hypertension: 233,000 (10.6%)

Stroke: 14,000 (0.6%)

MentalDisorders: 301,000 (13.6%)

PulmonaryConditions: 263,000 (11.9%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Nevada, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Nevada of $7.5 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $1.9

Lost Productivity: $7.5

Total Costs: $9.4

Economic Impact in Nevada 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 58: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Nevada (continued)

0 100 200 300 400 500 600 700 800

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

570

165

376

170

394

146

80

87

87

65

20 5

26

32

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices — Chronic Disease in Nevada TOMORROWOn our current path, Nevada will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 381,000cases of chronic conditions in 2023.

0

10

20

30

40

50

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$9.4

$19.2

$2.7

$32.3

$12.2

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Nevada sharply, by 27% ($12.2 billion) in 2023. $9.1 billion of this would come from gains in productivity,and $3.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $96 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $545

GDP in 2050, Alternative Path: $641

Potential Gain in GDP: $96 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$10.4 $34.1 $44.4

AlternativePath

$7.3 $25.0 $32.3

CostsAvoided

$3.1(30%)

$9.1(27%)

$12.2(27%)

Page 59: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NEW HAMPSHIRE

2006 Population1,314,895

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Current Toll on New Hampshire TODAYOver 680,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in New Hampshire in 2003. These conditions shorten lives, reducequality of life, and create considerable burden for caregivers.The following map shows how states compare based on theprevalence of the seven common chronic diseases.

Cancers: 50,000 (4.0%)

Diabetes: 52,000 (4.2%)

HeartDisease: 73,000 (5.8%)

Hypertension: 149,000 (11.9%)

Stroke: 9,000 (0.7%)

MentalDisorders: 117,000 (9.3%)

PulmonaryConditions: 231,000 (18.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in New Hampshire, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.0 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in New Hampshire of $4.4 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $1.0

Lost Productivity: $4.4

Total Costs: $5.4

Economic Impact in New Hampshire 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 60: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on New Hampshire (continued)

0 50 100 150 200 250 300 350

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

166

79

180

82

280

73

23

42

41

45

11 2

12

16

Reported Cases (Thousands)

B

Cases Avoided ifAlternative Path is Taken

C

Two Paths, Two Choices— Chronic Disease in New Hampshire TOMORROWOn our current path, New hampshire will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 183,000cases of chronic conditions in 2023.

0

5

10

15

20

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$5.4

$9.6

$1.3

$13.6

$5.2

C

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in New Hampshire sharply, by 27% ($5.2 billion) in 2023. $4.3 billion of this would come from gains in productivity,and $0.9 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $26 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $146

GDP in 2050, Alternative Path: $171

Potential Gain in GDP: $26 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$3.4 $15.5 $18.8

AlternativePath

$2.4 $11.2 $13.6

CostsAvoided

$0.9(27%)

$4.3(28%)

$5.2(27%)

Page 61: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NEW JERSEY

2006 Population8,724,560

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Current Toll on New Jersey TODAYOver 4.6 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in New Jersey in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 353,000 (4.2%)

Diabetes: 440,000 (5.2%)

HeartDisease: 589,000 (7.0%)

Hypertension: 1,137,000 (13.5%)

Stroke: 65,000 (0.8%)

MentalDisorders: 742,000 (8.8%)

PulmonaryConditions: 1,295,000 (15.3%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in New Jersey, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $7.5 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in New Jersey of $31.5 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $7.5

Lost Productivity: $31.5

Total Costs: $39.0

Economic Impact in New Jersey 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 62: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on New Jersey (continued)

0 500 1,000 1,500 2,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

925

499

1,214

541

1,360

432

130

264

280

222

61 14

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

82

94

Two Paths, Two Choices — Chronic Disease in New Jersey TOMORROWOn our current path, New Jersey will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid1.1 million cases of chronic conditions in 2023.

0

20

40

60

80

100

120

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$39

$63

$9

$82

$31Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in New Jersey sharply, by 27% ($31 billion) in 2023. $26 billion of this would come from gains in productivity, and$5 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $167 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $952

GDP in 2050, Alternative Path: $1,119

Potential Gain in GDP: $167 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$19 $94 $113

AlternativePath

$14 $68 $82

CostsAvoided

$5(26%)

$26(28%)

$31(27%)

Page 63: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NEW MEXICO

2006 Population1,954,599

L

Current Toll on New Mexico TODAYNearly 890,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in New Mexico in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity82%

Treatment Expenditures18%

Treatment Expenditures: $1.2

Lost Productivity: $5.8

Total Costs: $7.0

Economic Impact in New Mexico 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 56,000 (3.0%)

Diabetes: 66,000 (3.6%)

HeartDisease: 92,000 (5.0%)

Hypertension: 175,000 (9.5%)

Stroke: 11,000 (0.6%)

MentalDisorders: 264,000 (14.4%)

PulmonaryConditions: 224,000 (12.2%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in New Mexico, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.2 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in New Mexico of $5.8 billion in 2003.

Page 64: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on New Mexico (continued)

0 100 200 300 400 500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

359

112

211

104

232

75

130

59

48

38

13 3

16

16

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

51

Two Paths, Two Choices — Chronic Disease in New Mexico TOMORROWOn our current path, New Mexico will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 232,000cases of chronic conditions in 2023.

0

5

10

15

20

25

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$7.0

$12.4

$1.6

$17.5

$6.3

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in New Mexico sharply, by 26% ($6.3 billion) in 2023. $5.2 billion of this would come from gains in productivity, and$1.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $26 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $149

GDP in 2050, Alternative Path: $175

Potential Gain in GDP: $26 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$3.9 $19.8 $23.7

AlternativePath

$2.9 $14.6 $17.5

CostsAvoided

$1.1(27%)

$5.2(26%)

$6.3(26%)

Page 65: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NEW YORK

2006 Population19,306,183

L

Current Toll on New York TODAYNearly 10.5 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, men-tal disorders, and pulmonary conditions — were reported in New York in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 714,000 (3.8%)

Diabetes: 1,020,000 (5.5%)

HeartDisease: 1,477,000 (7.9%)

Hypertension: 2,501,000 (13.4%)

Stroke: 119,000 (0.6%)

MentalDisorders: 1,572,000 (8.5%)

PulmonaryConditions: 3,086,000 (16.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in New York, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $19.1 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in New York of $69.0 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $19.1

Lost Productivity: $69.0

Total Costs: $88.0

Economic Impact in New York 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 66: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on New York (continued)

0 500 1,000 1,500 2,000 2,500 3,000 3,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,808

1,155

2,422

1,126

2,993

808

254

612

103 24

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

556

173

489

174

Two Paths, Two Choices — Chronic Disease in New York TOMORROWOn our current path, New York will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 2.3 millioncases of chronic conditions in 2023.

0

50

100

150

200

250

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$88

$134

$18

$169

$64Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in New York sharply, by 27% ($64 billion) in 2023. $52 billion of this would come from gains in productivity, and$12 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $295 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $1,650

GDP in 2050, Alternative Path: $1,946

Potential Gain in GDP: $295 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$44 $188 $232

AlternativePath

$32 $136 $169

CostsAvoided

$12(27%)

$52(28%)

$64(27%)

Page 67: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NORTH CAROLINA

2006 Population8,856,505

Current Toll on North Carolina TODAYOver 5 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in North Carolina in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 297,000 (3.6%)

Diabetes: 427,000 (5.2%)

HeartDisease: 537,000 (6.6%)

Hypertension: 1,192,000 (14.6%)

Stroke: 80,000 (1.0%)

MentalDisorders: 993,000 (12.2%)

PulmonaryConditions: 1,513,000 (18.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in North Carolina, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $7.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in North Carolina of $32.1 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $7.9

Lost Productivity: $32.1

Total Costs: $40.0

Economic Impact in North Carolina2003 (Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 68: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on North Carolina (continued)

0 500 1,000 1,500 2,000 2,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,475

506

1,447

589

1,917

437

207

268

87 20

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

333

91

314

95

Two Paths, Two Choices — Chronic Disease in North Carolina TOMORROWOn our current path, North Carolina will experience a dramatic increase in chronic disease in the next 20 years. But thereis an alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid1.4 million cases of chronic conditions in 2023.

0

30

60

90

120

150

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$40

$70

$9

$103

$38Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in North Carolina sharply, by 27% ($38 billion) in 2023. $29 billion of this would come from gains in productivity, and$8 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $170 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $967

GDP in 2050, Alternative Path: $1,137

Potential Gain in GDP: $170 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$29 $111 $140

AlternativePath

$21 $82 $103

CostsAvoided

$8(29%)

$29(26%)

$38(27%)

Page 69: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on NORTH DAKOTA

2006 Population635,867

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Current Toll on North Dakota TODAYNearly 318,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in North Dakota in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 20,000 (3.3%)

Diabetes: 23,000 (3.8%)

HeartDisease: 47,000 (7.7%)

Hypertension: 78,000 (12.8%)

Stroke: 8,000 (1.3%)

MentalDisorders: 42,000 (6.9%)

PulmonaryConditions: 100,000 (16.4%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in North Dakota, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.8 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in North Dakota of $2.1 billion in 2003.

Lost Productivity73%

Treatment Expenditures27%

Treatment Expenditures: $0.8

Lost Productivity: $2.1

Total Costs: $2.8

Economic Impact in North Dakota 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 70: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on North Dakota (continued)

0 20 40 60 80 100 120

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

48

39

76

30

102

24

6

20

8 1

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

18

4

16

5

Two Paths, Two Choices— Chronic Disease in North Dakota TOMORROWOn our current path, North Dakota will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 73,000cases of chronic conditions in 2023.

0

1

2

3

4

5

6

7

8

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$2.8

$4.3

$0.6

$5.5

$2.1

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs of diseasein North Dakota sharply, by 28% ($2.1 billion) in 2023. $1.6 billion of this would come from gains in productivity, and $0.5 billionwould come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $7 billion to the state’s economic output, a boost of18%.

GDP in 2050, Current Path: $41

GDP in 2050, Alternative Path: $48

Potential Gain in GDP: $7 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$1.8 $5.8 $7.6

AlternativePath

$1.3 $4.2 $5.5

CostsAvoided

$0.5(29%)

$1.6(28%)

$2.1(28%)

Page 71: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on OHIO

2006 Population11,478,006

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Current Toll on Ohio TODAYOver 6.7 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Ohio in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalence ofthe seven common chronic diseases.

Cancers: 377,000 (3.4%)

Diabetes: 595,000 (5.3%)

HeartDisease: 875,000 (7.9%)

Hypertension: 1,549,000 (13.9%)

Stroke: 113,000 (1.0%)

MentalDisorders: 1,432,000 (12.9%)

PulmonaryConditions: 1,835,000 (16.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Ohio, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $13.5 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Ohio of $43.4 billion in 2003.

Lost Productivity76%

Treatment Expenditures24%

Treatment Expenditures: $13.5

Lost Productivity: $43.4

Total Costs: $56.8

Economic Impact in Ohio 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 72: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Ohio (continued)

0 500 1,000 1,500 2,000 2,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,646

689

1,503

663

1,886

445

232

365

102 24

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

346

101

308

97

Two Paths, Two Choices — Chronic Disease in Ohio TOMORROWOn our current path, Ohio will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 1.5 millioncases of chronic conditions in 2023.

0

50

100

150

200

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$57

$87

$12

$111

$40

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Ohio sharply, by 27% ($40 billion) in 2023. $32 billion of this would come from gains in productivity, and$9 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $151 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $854

GDP in 2050, Alternative Path: $1,005

Potential Gain in GDP: $151 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$32 $120 $152

AlternativePath

$23 $88 $111

CostsAvoided

$9(27%)

$32(26%)

$40(27%)

Page 73: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on OKLAHOMA

2006 Population3,579,212

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Current Toll on Oklahoma TODAYNearly 2.2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Oklahoma in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $ 3.3

Lost Productivity: $13.8

Total Costs: $17.0

Economic Impact in Oklahoma 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 135,000 (4.0%)

Diabetes: 158,000 (4.7%)

HeartDisease: 318,000 (9.4%)

Hypertension: 485,000 (14.3%)

Stroke: 38,000 (1.1%)

MentalDisorders: 360,000 (10.6%)

PulmonaryConditions: 674,000 (19.8%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Oklahoma, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $3.3 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Oklahoma of $13.8 billion in 2003.

Page 74: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Oklahoma (continued)

0 200 400 600 800 1,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

437

255

487

183

708

164

62

135

34 8

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

112

28

116

35

Two Paths, Two Choices — Chronic Disease in Oklahoma TOMORROWOn our current path, Oklahoma will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 496,000cases of chronic conditions in 2023.

0

10

20

30

40

50

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$17.0

$26.7

$3.7

$34.6

$13.2

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Oklahoma sharply, by 28% ($13.2 billion) in 2023. $10.8 billion of this would come from gains in productivity, and$2.4 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $44 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $248

GDP in 2050, Alternative Path: $292

Potential Gain in GDP: $44 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$8.5 $39.3 $47.8

AlternativePath

$6.0 $28.6 $34.6

CostsAvoided

$2.4(29%)

$10.8(27%)

$13.2(28%)

Page 75: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on OREGON

2006 Population3,700,758

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Current Toll on Oregon TODAYOver 2 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Oregon in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 123,000 (3.5%)

Diabetes: 138,000 (4.0%)

HeartDisease: 190,000 (5.5%)

Hypertension: 377,000 (10.8%)

Stroke: 35,000 (1.0%)

MentalDisorders: 627,000 (18.0%)

PulmonaryConditions: 590,000 (16.9%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Oregon, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $3.4 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Oregon of $13.1 billion in 2003.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $ 3.4

Lost Productivity: $13.1

Total Costs: $16.5

Economic Impact in Oregon 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 76: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Oregon (continued)

0 200 400 600 800 1,000 1,200

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

878

179

434

192

695

167

123

95

39 9

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

99

30

114

36

Two Paths, Two Choices — Chronic Disease in Oregon TOMORROWOn our current path, Oregon will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 506,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$16.5

$27.8

$3.6

$40.5

$14.0Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Oregon sharply, by 26% ($14.0 billion) in 2023. $11.1 billion of this would come from gains in productivity,and $3.0 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $63 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $357

GDP in 2050, Alternative Path: $419

Potential Gain in GDP: $ 63 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$11.1 $43.5 $54.5

AlternativePath

$ 8.1 $32.4 $40.5

CostsAvoided

$ 3.0(27%)

$11.1(25%)

$14.0(26%)

Page 77: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on PENNSYLVANIA

2006 Population12,440,621

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Current Toll on Pennsylvania TODAYNearly 7.8 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Pennsylvania in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 485,000 (4.1%)

Diabetes: 709,000 (5.9%)

HeartDisease: 1,017,000 (8.5%)

Hypertension: 1,684,000 (14.1%)

Stroke: 135,000 (1.1%)

MentalDisorders: 1,582,000 (13.3%)

PulmonaryConditions: 2,167,000 (18.2%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Pennsylvania, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $13.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Pennsylvania of $50.5 billion in 2003.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $13.6

Lost Productivity: $50.5

Total Costs: $64.1

Economic Impact in Pennsylvania 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 78: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Pennsylvania (continued)

0 500 1,000 1,500 2,000 2,500 3,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,830

783

1,655

798

2,224

564

258

415

122 28

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

381

122

364

122

Two Paths, Two Choices — Chronic Disease in Pennsylvania TOMORROWOn our current path, Pennsylvania will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid over1.7 million cases of chronic conditions in 2023.

0

50

100

150

200

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$64

$98

$13

$125

$45Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Pennsylvania sharply, by 27% ($45 billion) in 2023. $38 billion of this would come from gains in productivity,and $8 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $158 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $ 894

GDP in 2050, Alternative Path: $1,052

Potential Gain in GDP: $ 158 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$30 $140 $170

AlternativePath

$22 $103 $125

CostsAvoided

$ 8(26%)

$38(27%)

$45(27%)

Page 79: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on RHODE ISLAND

2006 Population1,067,610

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Current Toll on Rhode Island TODAYNearly 713,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Rhode Island in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 44,000 (4.2%)

Diabetes: 52,000 (5.0%)

HeartDisease: 80,000 (7.7%)

Hypertension: 160,000 (15.4%)

Stroke: 9,000 (0.9%)

MentalDisorders: 149,000 (14.4%)

PulmonaryConditions: 218,000 (21.0%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Rhode Island, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.2 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Rhode Island of $4.5 billion in 2003.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $1.2

Lost Productivity: $4.5

Total Costs: $5.7

Economic Impact in Rhode Island 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 80: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Rhode Island (continued)

0 50 100 150 200 250 300

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

180

65

163

63

225

52

26

35

9 2

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

38

9

37

11

Two Paths, Two Choices— Chronic Disease in Rhode Island TOMORROWOn our current path, Rhode Island will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 157,000cases of chronic conditions in 2023.

0

5

10

15

20

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$5.7

$9.0

$1.2

$11.9

$4.3Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs of diseasein Rhode Island sharply, by 26% ($4.3 billion) in 2023. $3.4 billion of this would come from gains in productivity, and$0.8 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $19 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $111

GDP in 2050, Alternative Path: $130

Potential Gain in GDP: $ 19 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$3.1 $13.0 $16.1

AlternativePath

$2.3 $ 9.6 $11.9

CostsAvoided

$0.8(27%)

$ 3.4(26%)

$ 4.3(26%)

Page 81: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on SOUTH CAROLINA

2006 Population4,321,249

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Current Toll on South Carolina TODAYOver 2.5 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in South Carolina in 2003. These conditions shorten lives, reducequality of life, and create considerable burden for caregivers. The following map shows how states compare based on theprevalence of the seven common chronic diseases.

Cancers: 164,000 (4.1%)

Diabetes: 242,000 (6.0%)

HeartDisease: 273,000 (6.8%)

Hypertension: 591,000 (14.7%)

Stroke: 42,000 (1.0%)

MentalDisorders: 564,000 (14.1%)

PulmonaryConditions: 640,000 (16.0%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in South Carolina, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $4.0 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in South Carolina of $16.8 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $ 4.0

Lost Productivity: $16.8

Total Costs: $20.8

Economic Impact in South Carolina 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 82: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on South Carolina (continued)

0 200 400 600 800 1,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

783

289

700

333

750

234

111

153

48 11

Reported Cases (Thousands)

Cases Avoided ifAlternative Pathis Taken

161

51

122

51

Two Paths, Two Choices — Chronic Disease in South Carolina TOMORROWOn our current path, South Carolina will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 660,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

70

80

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$20.8

$36.7

$5.0

$52.0

$19.3Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in South Carolina sharply, by 27% ($19.3 billion) in 2023. $15.3 billion of this would come from gains in productivity, and$4.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $66 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $376

GDP in 2050, Alternative Path: $443

Potential Gain in GDP: $ 66 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$14.0 $57.3 $71.3

AlternativePath

$ 9.9 $42.0 $52.0

CostsAvoided

$ 4.1(29%)

$15.3(27%)

$19.3(27%)

Page 83: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on SOUTH DAKOTA

2006 Population781,919

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Current Toll on South Dakota TODAYNearly 436,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in South Dakota in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity75%

Treatment Expenditures25%

Treatment Expenditures: $0.9

Lost Productivity: $2.8

Total Costs: $3.8

Economic Impact in South Dakota 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 29,000 (3.9%)

Diabetes: 32,000 (4.4%)

HeartDisease: 55,000 (7.5%)

Hypertension: 98,000 (13.3%)

Stroke: 8,000 (1.1%)

MentalDisorders: 89,000 (12.1%)

PulmonaryConditions: 126,000 (17.1%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in South Dakota, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in South Dakota of $2.8 billion in 2003.

Page 84: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on South Dakota (continued)

0 50 100 150 200

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

106

47

101

43

134

35

15

25

8 1

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

23

7

22

8

Two Paths, Two Choices — Chronic Disease in South Dakota TOMORROWOn our current path, South Dakota will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 101,000cases of chronic conditions in 2023.

0

2

4

6

8

10

12

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$3.8

$6.1

$0.8

$8.0

$3.1Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in South Dakota sharply, by 28% ($3.1 billion) in 2023. $2.3 billion of this would come from gains in productivity,and $0.8 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $10 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $56

GDP in 2050, Alternative Path: $66

Potential Gain in GDP: $10 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$2.7 $8.4 $11.1

AlternativePath

$1.9 $6.1 $8.0

CostsAvoided

$0.8(30%)

$2.3(27%)

$3.1(28%)

Page 85: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on TENNESSEE

2006 Population6,038,803

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Current Toll on Tennessee TODAYNearly 3.8 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Tennessee in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 260,000 (4.6%)

Diabetes: 344,000 (6.0%)

HeartDisease: 458,000 (8.1%)

Hypertension: 876,000 (15.4%)

Stroke: 59,000 (1.0%)

MentalDisorders: 624,000 (11.0%)

PulmonaryConditions: 1,167,000 (20.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Tennessee, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $6.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Tennessee of $24.7 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $6.9

Lost Productivity: $24.7

Total Costs: $31.6

Economic Impact in Tennessee 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 86: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Tennessee (continued)

0 500 1,000 1,500 2,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

845

416

964

431

1,375

358

119

220

61 14

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

221

67

225

78

Two Paths, Two Choices — Chronic Disease in Tennessee TOMORROWOn our current path, Tennessee will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 944,000cases of chronic conditions in 2023.

0

20

40

60

80

100

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$31.6

$52.7

$7.3

$72.1

$27.3

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Tennessee sharply, by 27% ($27.3 billion) in 2023. $21.8 billion of this would come from gains in productivity,and $5.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $93 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $528

GDP in 2050, Alternative Path: $621

Potential Gain in GDP: $93 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$20.0 $79.4 $99.4

AlternativePath

$14.4 $57.6 $72.1

CostsAvoided

$5.6(28%)

$21.8(27%)

$27.3(27%)

Page 87: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on TEXAS

2006 Population23,507,783

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Current Toll on Texas TODAYNearly 11.7 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Texas in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 797,000 (3.7%)

Diabetes: 1,122,000 (5.2%)

HeartDisease: 1,201,000 (5.6%)

Hypertension: 2,689,000 (12.5%)

Stroke: 158,000 (0.7%)

MentalDisorders: 1,866,000 (8.7%)

PulmonaryConditions: 3,857,000 (17.9%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Texas, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $17.2 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Texas of $75.3 billion in 2003.

Lost Productivity81%

Treatment Expenditures19%

Treatment Expenditures: $17.2

Lost Productivity: $75.3

Total Costs: $92.5

Economic Impact in Texas 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 88: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Texas (continued)

0 1,000 2,000 3,000 4,000 5,000 6,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

2,885

1,267

3,450

1,666

4,784

1,192

406

671

188 43

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

794

255

782

258

Two Paths, Two Choices — Chronic Disease in Texas TOMORROWOn our current path, Texas will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid over 3.2million cases of chronic conditions in 2023.

0

50

100

150

200

250

300

350

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$92

$165

$22

$242

$90

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Texas sharply, by 27% ($90 billion) in 2023. $74 billion of this would come from gains in productivity, and $17 billionwould come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $520 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $2,947

GDP in 2050, Alternative Path: $3,467

Potential Gain in GDP: $520 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$59 $273 $332

AlternativePath

$43 $199 $242

CostsAvoided

$17(28%)

$74(27%)

$90(27%)

Page 89: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on UTAH

2006 Population2,550,063

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Current Toll on Utah TODAYOver 1 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Utah in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalence of theseven common chronic diseases.

Cancers: 71,000 (3.1%)

Diabetes: 81,000 (3.5%)

HeartDisease: 82,000 (3.6%)

Hypertension: 197,000 (8.5%)

Stroke: 12,000 (0.5%)

MentalDisorders: 305,000 (13.2%)

PulmonaryConditions: 313,000 (13.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Utah, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $1.5 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Utah of $6.8 billion in 2003.

Lost Productivity82%

Treatment Expenditures18%

Treatment Expenditures: $1.5

Lost Productivity: $6.8

Total Costs: $8.3

Economic Impact in Utah 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 90: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Utah (continued)

0 100 200 300 400 500 600

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

461

85

253

134

392

105

64

45

14 3

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

58

21

64

23

Two Paths, Two Choices— Chronic Disease in Utah TOMORROWOn our current path, Utah will experience a dramatic increase in chronic disease in the next 20 years. But there is an alternativepath. By making reasonable improvements in preventing and managing chronic disease, we can avoid 279,000 cases of chronicconditions in 2023.

0

5

10

15

20

25

30

35

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$8.3

$14.8

$1.9

$22.5

$7.9Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs of diseasein Utah sharply, by 26% ($7.9 billion) in 2023. $6.4 billion of this would come from gains in productivity, and $1.5 billion wouldcome from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $54 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $306

GDP in 2050, Alternative Path: $360

Potential Gain in GDP: $54 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$5.4 $25 $30.4

AlternativePath

$3.9 $18.5 $22.5

CostsAvoided

$1.5(27%)

$6.4(26%)

$7.9(26%)

Page 91: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on VERMONT

2006 Population623,908

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Current Toll on Vermont TODAYNearly 362,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Vermont in 2003. These conditions shorten lives, reduce quality of life,and create considerable burden for caregivers. The following map shows how states compare based on the prevalence of theseven common chronic diseases.

Cancers: 23,000 (3.8%)

Diabetes: 26,000 (4.3%)

HeartDisease: 36,000 (6.0%)

Hypertension: 74,000 (12.4%)

Stroke: 5,000 (0.8%)

MentalDisorders: 89,000 (14.9%)

PulmonaryConditions: 110,000 (18.4%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Vermont, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.6 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Vermont of $2.3 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $0.6

Lost Productivity: $2.3

Total Costs: $2.9

Economic Impact in Vermont 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 92: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Vermont (continued)

0 30 60 90 120 150

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

120

39

83

39

127

32

17

21

6 1

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

19

6

21

7

Two Paths, Two Choices — Chronic Disease in Vermont TOMORROWOn our current path, Vermont will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 92,000cases of chronic conditions in 2023.

0

2

4

6

8

10

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$2.9

$5.1

$0.7

$7.2

$2.6

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Vermont sharply, by 27% ($2.6 billion) in 2023. $2 billion of this would come from gains in productivity, and$0.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $10 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $56

GDP in 2050, Alternative Path: $66

Potential Gain in GDP: $10 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$2.1 $7.7 $9.8

AlternativePath

$1.5 $5.7 $7.2

CostsAvoided

$0.6(28%)

$2.0(26%)

$2.6(27%)

Page 93: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on VIRGINIA

2006 Population7,642,884

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Current Toll on Virginia TODAYOver 4 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Virginia in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Lost Productivity82%

Treatment Expenditures18%

Treatment Expenditures: $ 5.9

Lost Productivity: $26.2

Total Costs: $32.2

Economic Impact in Virginia 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Cancers: 279,000 (3.9%)

Diabetes: 333,000 (4.7%)

HeartDisease: 424,000 (5.9%)

Hypertension: 891,000 (12.5%)

Stroke: 60,000 (0.8%)

MentalDisorders: 739,000 (10.3%)

PulmonaryConditions: 1,419,000 (19.8%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Virginia, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $5.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Virginia of $26.2 billion in 2003.

Page 94: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Virginia (continued)

0 500 1,000 1,500 2,000

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,062

432

1,041

443

1,706

405

150

228

239

279

68 16

68

88

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices — Chronic Disease in Virginia TOMORROWOn our current path, Virginia will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid over1 million cases of chronic conditions in 2023.

0

20

40

60

80

100

120

Billi

ons

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rs(N

omin

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2003 2013 2023

$32

$56

$8

$79

$30Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Virginia sharply, by 27% ($30 billion) in 2023. $24 billion of this would come from gains in productivity, and$5 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $171 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $ 971

GDP in 2050, Alternative Path: $1,142

Potential Gain in GDP: $ 171 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$19 $89 $109

AlternativePath

$14 $65 $ 79

CostsAvoided

$ 5(28%)

$24(27%)

$ 30(27%)

Page 95: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on WASHINGTON

2006 Population6,395,798

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Current Toll on Washington TODAYNearly 3 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Washington in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 222,000 (3.7%)

Diabetes: 249,000 (4.2%)

HeartDisease: 302,000 (5.0%)

Hypertension: 644,000 (10.8%)

Stroke: 49,000 (0.8%)

MentalDisorders: 307,000 (5.1%)

PulmonaryConditions: 993,000 (16.6%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Washington, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $4.9 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Washington of $18.2 billion in 2003.

Lost Productivity79%

Treatment Expenditures21%

Treatment Expenditures: $ 4.9

Lost Productivity: $18.2

Total Costs: $23.1

Economic Impact in Washington 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 96: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Washington (continued)

0 300 600 900 1,200 1,500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

448

319

782

362

1,195

321

63

168

180

195

59 14

56

69

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices — Chronic Disease in Washington TOMORROWOn our current path, Washington will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 746,000cases of chronic conditions in 2023.

0

10

20

30

40

50

60

70

80

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$23.1

$39.7

$5.7

$57.4

$22.6

Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Washington sharply, by 28% ($22.6 billion) in 2023. $17.9 billion of this would come from gains in productivity,and $4.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $173 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $ 983

GDP in 2050, Alternative Path: $1,156

Potential Gain in GDP: $ 173 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$16.3 $63.6 $80.0

AlternativePath

$11.7 $45.7 $57.4

CostsAvoided

$ 4.6(28%)

$17.9(28%)

$22.6(28%)

Page 97: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on WEST VIRGINIA

2006 Population1,818,470

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Current Toll on West Virginia TODAYNearly 1.3 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in West Virginia in 2003. These conditions shorten lives, reduce qualityof life, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 72,000 (4.1%)

Diabetes: 111,000 (6.3%)

HeartDisease: 178,000 (10.1%)

Hypertension: 301,000 (17.0%)

Stroke: 20,000 (1.1%)

MentalDisorders: 225,000 (12.7%)

PulmonaryConditions: 371,000 (21.0%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in West Virginia, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $2.3 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in West Virginia of $8.1 billion in 2003.

Lost Productivity78%

Treatment Expenditures22%

Treatment Expenditures: $ 2.3

Lost Productivity: $ 8.1

Total Costs: $10.5

Economic Impact in West Virginia 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 98: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on West Virginia (continued)

0 100 200 300 400 500

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

254

145

290

130

383

85

36

77

67

63

18 4

20

19

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices — Chronic Disease in West Virginia TOMORROWOn our current path, West Virginia will experience a dramatic increase in chronic disease in the next 20 years. But there isan alternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 285,000cases of chronic conditions in 2023.

0

5

10

15

20

25

30

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$10.5

$16.4

$2.2

$20.6

$7.7Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in West Virginia sharply, by 27% ($7.7 billion) in 2023. $6.1 billion of this would come from gains in productivity,and $1.6 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $16 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $ 92

GDP in 2050, Alternative Path: $108

Potential Gain in GDP: $ 16 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$5.6 $22.6 $28.2

AlternativePath

$4.1 $16.5 $20.6

CostsAvoided

$1.6(28%)

$ 6.1(27%)

$ 7.7(27%)

Page 99: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on WISCONSIN

2006 Population5,556,506

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Current Toll on Wisconsin TODAYOver 3 million cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mentaldisorders, and pulmonary conditions — were reported in Wisconsin in 2003. These conditions shorten lives, reduce quality oflife, and create considerable burden for caregivers. The following map shows how states compare based on the prevalenceof the seven common chronic diseases.

Cancers: 185,000 (3.5%)

Diabetes: 192,000 (3.6%)

HeartDisease: 356,000 (6.7%)

Hypertension: 685,000 (12.9%)

Stroke: 53,000 (1.0%)

MentalDisorders: 812,000 (15.3%)

PulmonaryConditions: 928,000 (17.5%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Wisconsin, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $6.2 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Wisconsin of $20.2 billion in 2003.

Lost Productivity76%

Treatment Expenditures24%

Treatment Expenditures: $ 6.2

Lost Productivity: $20.2

Total Costs: $26.4

Economic Impact in Wisconsin 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 100: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Wisconsin (continued)

0 200 400 600 800 1,000 1,200

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

1,025

320

745

248

1,009

236

145

169

172

164

54 13

38

51

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices— Chronic Disease in Wisconsin TOMORROWOn our current path, Wisconsin will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 752,000cases of chronic conditions in 2023.

0

20

40

60

80

100

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$26.4

$43.3

$5.7

$59.0

$21.3Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Wisconsin sharply, by 27% ($21.3 billion) in 2023. $16.2 billion of this would come from gains in productivity,and $5.1 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $85 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $483

GDP in 2050, Alternative Path: $568

Potential Gain in GDP: $ 85 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$18.2 $62 $80.2

AlternativePath

$13.1 $45.8 $59.0

CostsAvoided

$ 5.1(28%)

$16.2(26%)

$21.3(27%)

Page 101: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on WYOMING

2006 Population515,004

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Current Toll on Wyoming TODAY235,000 cases of seven common chronic diseases — cancers, diabetes, heart disease, hypertension, stroke, mental disorders,and pulmonary conditions — were reported in Wyoming in 2003. These conditions shorten lives, reduce quality of life, and cre-ate considerable burden for caregivers. The following map shows how states compare based on the prevalence of the sevencommon chronic diseases.

Cancers: 17,000 (3.5%)

Diabetes: 18,000 (3.7%)

HeartDisease: 26,000 (5.3%)

Hypertension: 53,000 (10.9%)

Stroke: 3,000 (0.6%)

MentalDisorders: 51,000 (10.5%)

PulmonaryConditions: 67,000 (13.7%)

* As % of non-institutionalized population. Number oftreated cases based on patient self-reported data from2003 MEPS. Excludes untreated and undiagnosed cases.

Reported Cases in Wyoming, 2003(and as % of population*)

Top Quartile

Second

Third

Bottom Quartile

2

Milken Institute State Chronic Disease IndexStates in the top quartile have the lowest rates of seven common chronic diseases.

T

And while the human cost is enormous, the economic cost also is great. The cost of treating these conditions — withouteven taking into consideration the many secondary health problems they cause — totaled $0.4 billion in 2003. These conditionsalso reduce productivity at the workplace, as ill employees and their caregivers are often forced either to miss work days(absenteeism) or to show up but not perform well (presenteeism). The impact of lost workdays and lower employee productivityresulted in an annual economic loss in Wyoming of $1.6 billion in 2003.

Lost Productivity80%

Treatment Expenditures20%

Treatment Expenditures: $0.4

Lost Productivity: $1.6

Total Costs: $2.0

Economic Impact in Wyoming 2003(Annual Costs in Billions)

From: DeVol, Ross, and Armen Bedroussian, An Unhealthy America: The Economic Burden of Chronic Disease, Milken Institute, October 2007.Report prepared with support from the Pharmaceutical Research and Manufacturers of America. Report available at www.milkeninstitute.org.

Figures may not sum due to rounding.

Page 102: THE UNITED STATES The Economic Burden of Chronic Disease on

The Economic Burden of Chronic Disease on Wyoming (continued)

0 10 20 30 40 50 60 70 80

Mental Disorders

Stroke

Hypertension

Heart Disease

Diabetes

Pulmonary Conditions

Cancers

66

32

60

28

69

22

9

17

13

11

4 1

4

5

Reported Cases (Thousands)

Cases Avoided ifAlternative Path is Taken

Two Paths, Two Choices — Chronic Disease in Wyoming TOMORROWOn our current path, Wyoming will experience a dramatic increase in chronic disease in the next 20 years. But there is analternative path. By making reasonable improvements in preventing and managing chronic disease, we can avoid 61,000cases of chronic conditions in 2023.

0

1

2

3

4

5

6

7

8

Billi

ons

ofD

olla

rs(N

omin

al)

2003 2013 2023

$2.0

$3.4

$0.5

$4.7

$1.8Costs Avoided ifAlternative Pathis Taken

Reasonable improvements in preventing and managing chronic disease could reduce future economic costs ofdisease in Wyoming sharply, by 28% ($1.8 billion) in 2023. $1.4 billion of this would come from gains in productivity,and $0.4 billion would come from reduced treatment spending.

Avoidable Costs in 2023 (Billions)

And the impact on economic output compounds over time.These improvements in health will increase investments in humanand physical capital, driving additional economic growth a generationfrom now. By 2050, reasonable disease prevention and managementefforts could add $9 billion to the state’s economic output, a boostof 18%.

GDP in 2050, Current Path: $52

GDP in 2050, Alternative Path: $61

Potential Gain in GDP: $ 9 (18%)

Real GDP in 2050(In billions 2003 dollars)

Number of Cases in 2023 (Thousands)

Projected Annual Economic Costs 2003-2023 (Billions)

Figures may not sum due to rounding.

TreatmentExpenditures

LostProductivity

Total

CurrentPath

$1.4 $5.2 $6.5

AlternativePath

$1.0 $3.8 $4.7

CostsAvoided

$0.4(29%)

$1.4(27%)

$1.8(28%)