The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter...
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![Page 1: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/1.jpg)
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet, Jian-Guo Zhang, Silvia Alvarez-Diaz, Rowena Lewis, Najoua Lalaoui, Donald Metcalf, Andrew I. Webb, Samuel N. Young, Leila N. Varghese, Gillian M. Tannahill, Esme C. Hatchell, Ian J. Majewski, Toru Okamoto, Renwick C.J. Dobson, Douglas J. Hilton, Jeffrey J. Babon, Nicos A. Nicola, Andreas Strasser, John Silke,
Warren S. Alexander
Immunity Volume 39, Issue 3, Pages 443-453 (September 2013)
DOI: 10.1016/j.immuni.2013.06.018
Copyright © 2013 Elsevier Inc. Terms and Conditions
![Page 2: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/2.jpg)
Figure 1
Immunity 2013 39, 443-453DOI: (10.1016/j.immuni.2013.06.018) Copyright © 2013 Elsevier Inc. Terms and Conditions
![Page 3: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/3.jpg)
Figure 2
Immunity 2013 39, 443-453DOI: (10.1016/j.immuni.2013.06.018) Copyright © 2013 Elsevier Inc. Terms and Conditions
![Page 4: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/4.jpg)
Figure 3
Immunity 2013 39, 443-453DOI: (10.1016/j.immuni.2013.06.018) Copyright © 2013 Elsevier Inc. Terms and Conditions
![Page 5: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/5.jpg)
Figure 4
Immunity 2013 39, 443-453DOI: (10.1016/j.immuni.2013.06.018) Copyright © 2013 Elsevier Inc. Terms and Conditions
![Page 6: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/6.jpg)
Figure 5
Immunity 2013 39, 443-453DOI: (10.1016/j.immuni.2013.06.018) Copyright © 2013 Elsevier Inc. Terms and Conditions
![Page 7: The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet,](https://reader034.fdocuments.in/reader034/viewer/2022042608/5697bf811a28abf838c85360/html5/thumbnails/7.jpg)
Figure 6
Immunity 2013 39, 443-453DOI: (10.1016/j.immuni.2013.06.018) Copyright © 2013 Elsevier Inc. Terms and Conditions