The predominant pathway for early vision · Chen-Bee, Zhou, Jacobs, Lim, Frostig (Frontiers of...
Transcript of The predominant pathway for early vision · Chen-Bee, Zhou, Jacobs, Lim, Frostig (Frontiers of...
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The predominant pathway for "early" vision
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Vision starts in the eye - and is largely mapped 1:1 across space (retinotopy)
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Many output cells from the retina, i.e., retinal ganglion cells, have a ∇2 receptive field
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Visual information travels from retina to thalamus to cortex
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Wandell, Dumoulin, Brewer (Neuron 2007)
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Larsson and Heeger (J Neuroscience 2006)
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Cortex synthesizes orientation preference from ∇2 receptive fields
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Continuous coding variables, like orientation, in primate vision, are mapped
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The representation of continuous coding variables can be imaged across cortex
These features are mapped across visual cortex in primates and cats, as seen by intrinsic optical imaging
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Nearby neurons have similar receptive field (but note discontinuities at spirals)
Grinvald, Lieke, Frostig, Gilbert, Wiesel (Nature 1986)
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Clarification of maps
Bonhoeffer and Grinvald (J Neuroscience 1993)
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Nearby neurons with similar receptive field have significant "noise" correlations
T'so, Gilbert, Wiesel (J Neuroscience 1986)
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Just a reminder - A mouse is not a monkey, and vice versa
Ohki, Chung, Ch’ng, Kara, Reid (Nature 2005)
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A conundrum is that the width of tuning is independent of the contrast (input strength)
Sclar and Freeman (Experimental Brain Research 1962) Ferster, Sooyoung, Wheat (Nature 1996)
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Cortical interactions, as opposed to solely feedforward features, define the tuning width
Crook, Kisvarday, Eysel (Visual Neuroscience 1997)
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Beyond vision, normalization of input signals is seen in other systems, e.g., the coding of touch by the vibrissa system of rodents
Chen-Bee, Zhou, Jacobs, Lim, Frostig (Frontiers of Neural Circuits 2012)
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Chen-Bee, Zhou, Jacobs, Lim, Frostig (Frontiers of Neural Circuits 2012)
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W0 = -0.4 and W2 = 4.0 ε = 0.09
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Bumps of activity in the heading direction system in rodent thalamus
Internally organized mechanisms of the head direction senseNature Neuroscience 2015Adrien Peyrache, Marie M Lacroix, Peter C Petersen & György Buzsáki
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Bumps of activity in the landmark heading system in the fly ellipsoid body of the central complex thalamus
Neural dynamics for landmark orientation and angular path integrationNatureJohannes D. Seelig & Vivek Jayaraman
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Neural dynamics for landmark orientation and angular path integrationNatureJohannes D. Seelig & Vivek Jayaraman