The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for...
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Transcript of The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for...
![Page 1: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/1.jpg)
The Pleura
![Page 2: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/2.jpg)
The Pleura
A mesothelial surface lining the lungs and mediastinum
Mesothelial cells designed for fluid absorption
Hallmark of disease is the effusion
![Page 3: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/3.jpg)
Pleural Effusion
Transudate (low protein) cardiac failure hypoproteinaemia
Exudate (high protein) pneumonia TB connective tissue
disease malignancy (primary
or metastatic)
![Page 4: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/4.jpg)
Purulent Effusion
Full of acute inflammatory cells Empyema Can become chronic
![Page 5: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/5.jpg)
Pneumothorax
Air in pleural space Trauma Rupture of bulla
![Page 6: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/6.jpg)
Large bullae
![Page 7: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/7.jpg)
Pleural Neoplasia
Primary benign (rare) malignant mesothelioma
Secondary common (adenocarcinomas - lung, GIT,
ovary)
![Page 8: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/8.jpg)
Mesothelioma
![Page 9: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/9.jpg)
Pleural biopsy - mesothelioma
Mixed spindle cell (mesenchymal) and epithelial differentiation
![Page 10: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/10.jpg)
Metastases in Pleura
![Page 11: The Pleura. A mesothelial surface lining the lungs and mediastinum Mesothelial cells designed for fluid absorption Hallmark of disease is the effusion.](https://reader036.fdocuments.in/reader036/viewer/2022081700/56649f415503460f94c60e05/html5/thumbnails/11.jpg)
Differential diagnosis of malignant effusions…..
Cytology, biopsy Difficult Immunohistochemistry for lineage
specific antigens may help Medicolegal importance