The Pancreas- By Chibesa Mumba
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Transcript of The Pancreas- By Chibesa Mumba
THE PANCREASBy Chibesa Mumba
Contents
What it is? What its made up of? Exocrine and endocrine cells? Pancreatic diseases Thought-provoking question
What is it?
A gland that secretes digestive enzymes into the gut
What is it made of
99% acini Pancreatic duct Islet of Langerhans
Islet of Langerhans
Discovered by Paul Langerhans in 1869 Group of cells that stand out from
surrounding cells Cells inside islet include A,B,D,F & Epsilon
cells
Islet cells
Alpha cells produce glucagon Beta cells produce insulin & amylin Delta cells produce somatostatin F/PP cells produce pancreatic polypeptide Epsilon cells produce ghrelin
Endocrine or Exocrine?
Type of Gland Location Cell Function Comments/Key points
Endocrine Islet periphery Alpha Glucagon production Glucagon is a hormone that increases the sugar in the blood
Endocrine Islet center Beta Insulin & amylin production Insulin decreases the sugar level in the blood & amylin gives humans a full feelingEndocrine Inside islet or islet periphery Delta Somatostatin production Somatostatin is a growth inhibiting hormoneEndocrine Islet periphery PP (F) Pancreatic Polypeptide production Pancreatic polypeptide controls the activities of the pancreasEndocrine Inside islet Epsilon Gherin production Gherin is a hormone that stimulates hungarExocrine Around exterior of pancreas Acini Digetive enzyme production and secretion Acini makes 99% of the pancreas
Diseases
Pancreatitis Pancreatic cancer Diabetes Mellitus
Pancreatitis
Severe abdominal pain occurs suddenly Can cause internal bleeding or shock Excess alcohol ingestion & gallstones are
causes Can give pancreas trauma
ACUTE
Pancreatic cancer
Also called pancreatic carcinoma Common type are exocrine tumors Endocrine tumors are usually malignant
Thought-provoking Questions
Impact of amylin on weight control Impact of somatostatin on ageing
THE END