The Mitochondria!
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Transcript of The Mitochondria!
The Mitochondria!
Review of Membranes…
A
BC
D
E
F
G
AB C
F
E
D
G
Outer membrane with porins
Outer compartment (cytosol)
Inner membrane with Cristae
MatrixEnzymes! Hexokinase (adds P to ADP) and Dehydrogenases (catalyze redox reactions)
Which of the following can get into the outer membrane?
MITOCHONDRIA
Mitochondria • Double membrane
– outer membrane– inner membrane
• highly folded cristae• enzymes & transport
proteins– intermembrane space
• fluid-filled space between membranes
intermembranespace inner
membrane
outermembrane
matrixcristae
Mitochondria — Structure• Double membrane energy harvesting organelle
– smooth outer membrane– highly folded inner membrane
• cristae– intermembrane space
• fluid-filled space between membranes– matrix
• inner fluid-filled space– DNA, ribosomes– enzymes
• free in matrix & membrane-bound
mitochondrialDNA
What cells would have a lot of mitochondria?
Mitochondria – Function
What does this tell us about the evolution of eukaryotes?
Endosymbiosis!
Dividing mitochondriaWho else divides like that?
Advantage of highly folded inner membrane?More surface area for membrane-bound enzymes & permeases
Membrane-bound proteinsEnzymes & permeases
bacteria!
The Real Deal
The Real Deal
Enzymes on the Outside
• Hexokinases- adds P onto ADP
• Dehydrogenases- catalyze REDOX– Transfers electrons (H) to an acceptor NAD or FAD
• FAD and NAD are electron carriers