Vol. 265, No. 26 The Journal of September 15, 1990

Biological Chemistry Copyright 0 1990 by the American Society for Biochemistry and Molecular Biology, Inc.

428 East Preston St., Baltimore, MD 21202 U.S.A.

CONTENTS*

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15365

15368

15371

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15379

15383

15387

15392

MINIREVIEW

Mutations that alter the primary structure of type I collagen. The perils of a system for generating large structures by the principle of nucleated growth.

Darwin J. Prockop

COMMUNICATIONS

Cyclic AMP induces insulin-like growth factor I synthesis in osteoblast-enriched cultures.

Thomas L. McCarthy, Michael Centrella, and Ernest0 Canalis

A novel metabolic form of the 32kDa-Dl protein in the grana-localized reaction center of photosystem II.

Franklin E. Callahan, Maria L. Ghirardi, Sudhir K. Sopory, Arkesh M. Mehta, Marvin Edelman, and Autar K. Mattoo

Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity.

William W. Wells, Dian Peng Xu, Yanfeng Yang, and Pamela A. Rocque

Antimicrobial peptide, tachyplesin I, isolated from hemocytes of the horseshoe crab (Tachypleus tri- dentutus). NMR determination of the &sheet struc- ture.

Keiichi Kawano, Takashi Yoneya, Toshiyuki Miyata, Katsuhiro Yoshikawa, Fuminori Tokunaga, Yoshihiro Terada, and Sadaaki Iwanaga

Inhibition by substrate of fructose l,B-bisphospha- tase purified from rat kidney cortex. Calculation of the kinetic constants of the enzyme.

Albert0 M. Vargas, Maria M. Sola, and Michel Bounias

Vasoactive intestinal peptide, a singlet oxygen - .- quencher.

Bibhu R. Misra and Hara P. Misra

Expression of mRNA coding for kidney and red cell water channels in Xenopus oocytes.

Rubin Zhang, Katherine A. Logee, and A. S. Verkman

Derivatives of somatic cell hybrids which carry the human gene locus for nephrogenic diabetes insipi- dus (NDI) express functional vasopressin renal VZ- type receptors.

David A. Jans, Bernard A. van Oost, Hilger H. Ropers, and Falk Fahrenholz

Characterization of a carbon monoxide complex of reduced dopamine &hydroxylase. Evidence for in- equivalence of the Cu(1) centers.

Ninian J. Blackburn, Trudie M. Pettingill, Karen S. Seagraves, and Ronald T. Shigeta

ARTICLES

Rapid induction of thymosin ,& in concanavalin A- stimulated thymocytes by translational control.

Bernd Schobitz, Roland Netzker, Ewald Hannappel, and Karl Brand

Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat.

William L. Rumsey, Cindy Schlosser, E. Matti Nuutinen, Michael Robiolio, and David F. Wilson

15400 Appendix. Oxygen transport to respiring myocytes. Keith E. Dionne

15403 Biosynthesis of heparin. G-Sulfation of D-ghcu- ronic acid units.

Marion Kusche and Ulf Lindahl

15410 Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate.

Kathryn A. Brozek and Christian R. H. Raetz

15418 A diacylglycerol kinase inhibitor, R 59 022, poten- tiates superoxide anion production and 46-kDa pro- tein phosphorylation in guinea pig polymorphonu- clear leukocytes.

Toshiaki Ohtsuka, Masanori Hiura, Kiyomi Yoshida, Naoki Okamura, and Sadahiko Ishibashi

15424 Isolation and characterization of the glycosamino- glycan component of rabbit thrombomodulin pro- teoglycan.

Marie-Claude Bourin, Evy Lundgren-Akerlund, and Ulf Lindahl

15432 Gene sequence and analysis of hsp30, a small heat shock protein of Neurospora crossa which associ- ates with mitochondria.

Nora Plesofsky- Vig and Robert Brambl

15441 Sodium fluoride prevents receptor- and protein ki- nase C-mediated activation of the human platelet Na+/H+ exchanger without inhibiting its basic pHI- regulating activity.

Winfried Siffert, Karl H. Jakobs, and Jan Willem N. Akkerman

15449 An ATP-modulated specific association of glycer- aldehyde-3-phosphate dehydrogenase with human erythrocyte glucose transporter.

Mohsen Lachaal, Charles J. Berenski, John Kim, and Chan Y. Jung

15455 A transcriptional enhancer essential for the expres- sion of the rat cholecystokinin gene contains a se- quence identical to the -296 element of the human c-fos gene.

Randy S. Haun and Jack E. Dixon

15464 The effects of NADPH and 3-hydroxy-3-methylglu- taryl-CoA on the thiobdisulfide redox behavior of rat liver microsomal 3-hydroxy-3-methylglutaryl- CoA reductase.

Roseann E. Cappel and Hiram F. Gilbert

15471 Nerve growth factor and fibroblast growth factor selectively activate a protein kinase that phospho- rylates high molecular weight microtubule-associ- ated proteins. Detection, partial purification, and characterization in PC12 cells.

Hensin Tsao, John M. Aletta, and Lloyd A. Greene

15481 Use of amber suppressors to investigate the ther- mostability of Bacillus Zicheniformis a-amylase. Amino acid replacements at 6 histidine residues reveal a critical position at His-133.

Nathalie Declerck, Philippe Joyet, Claude Gaillardin, and Jean-Michel Masson

* The CONTENTS arranged by Subject Categories will be found immediately following these CONTENTS. Full Instructions to Authors will be found in (1990) J. Biol. Chem. 265,595-605, and reprints may be obtained from the editorial office.

ii

15489 Adipose conversion of 3T3-Ll cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP.

Wilfried Schmidt, Gisela Poll-Jordan, and Georg Loffler

15496 Molecular cloning of cDNA encoding a 55-kDa mul- tifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum.

Larry Fliegel, Elizabeth Newton, Kimberly Burns, and Marek-Michalak

15503 Effects of phosphate and hydrophobic molecules on two mutations in the b-strand sector of the H+- ATPase from the yeast plasma membrane.

Andre Goffeau and Leopoldo de Meis

15506 Evaluation of the double-quantum filter for the measurement of intracellular sodium concentration.

Robert B. Hutchison, Deepak Malhotra, R. Edward Hendrick, Laurence Chan, and Joseph I. Shapiro

15511 Post-translational addition of an arginine moiety to acidic NH, termini of proteins is required for their recognition by ubiquitin-protein ligase.

Sarah Elias and Aaron Ciechanover

15518 Gene-enzyme relationship in the sulfate assimila- tion pathway of Saccharomyces cerevisiae. Study of the 3’-phosphoadenylylsulfate reductase struc- tural gene.

Dominique Thomas, Regine Barbey, and Yolande Surdin-Kerjan

15525 Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon, TnlO. The role of the conserved dipeptide, Serea-Asp“‘, in tetracycline transport.

Akihito Yamaguchi, Nobukazu Ono, Takaaki Akasaka, Takato Noumi, and Tetsuo Sawai

15531 A structural change in the Neurospora plasma membrane [H+]ATPase induced by N-ethylmaleim- ide.

Amy Chang and Carolyn W. Slayman

15537 Cloning and expression of the human SlOOj3 gene. Robert J. Allore, William C. Friend, David O’Hanlon,

Karen M. Neilson, Reuben Baumal, Robert J. Dunn, and Alexander Marks

15544 Pulmonary fibroblasts: an in vitro model of emphy- sema. Regulation of elastin gene expression.

Judith Ann Foster, Celeste B. Rich, and Mary F. Miller

15550 Synthesis of platelet-activating factor by endothe- lial cells. The role of G oroteins.

Ralph E. Whatley, Dan-F. Fennell, Jeffery A. Kurrus, Guy A. Zimmerman, Thomas M. McIntyre, and Stephen M. Prescott

15560 Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissues in vivo.

Paul H. A. Quax, C. Maria van den Hoogen, Jan H. Verheijen, Teresa Padro, Ron Zeheb, Thomas D. Gelehrter, Theo J. C. van Berkel, Johan Kuiper, and Jef J. Emeis

15564 Characterization of high affinity binding sites for charybdotoxin in synaptic plasma membranes from rat brain. Evidence for a direct association with an inactivating, voltage-dependent, potassium chan- nel.

Jesus Vazquez, Pamela Feigenbaum, V. Frank King, Gregory J. Kaczorowski, and Maria L. Garcia

15572 Carboxyl methylation and COOH-terminal process- ing of the brain G-protein y-subunit.

Peter S. Backlund, Jr., William F. Simonds, and Allen M. Spiegel

15577 The phagocyte 47-kilodalton cytosolic oxidase pro- tein is an early reactant in activation of the respi- ratory burst.

Michael E. Kleinberg, Harry L. Malech, and Daniel Rotrosen

15584 Localization of functional domains of the CAMP che- motactic receptor of Dictyostelium discoideum.

Yonping Tao and Claudette Klein

111

15590 Calcium binding to the H+,K+-ATPase. Evidence for a divalent cation site that is occupied during the catalytic cycle.

John Mendlein, Michael L. Ditmars, and George Sachs

15599 Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.

Alan D. Elbein, Joseph E. Tropea, Mike Mitchell, and GUF P. Kaushal

15606 Molecular cloning and heterologous expression of N-glycosidase F from Flavobacterium meningosep- ticum.

Daniela Lemp, Anton Haselbeck, and Franz Klebl

15611 Structure of the human laminin Bl chain gene. Reetta Vuolteenaho, Louise T. Chow, and Karl

Tryggvason

15617 Hepatic 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase. Use of site-directed mutagenesis to evaluate the roles of His-258 and His-392 in catal- ysis.

Albert Tauler, Kai Lin, and Simon J. Pilkis

15623 Transmembrane movement of heme. W. Richard Light III and John S. Olson

15632 The effects of linid comnosition on the rate and extent of heme binding to-membranes.

W. Richard Light III and John S. Olson

15638 Mutations in the aspartate receptor of Escherichia coli which affect aspartate binding.

Sherry L. Mowbray and Daniel E. Koshland, Jr.

15644 The neuroendocrine polypeptide 7B2 is a precursor protein.

Torik A. Y. Ayoubi, Hans L. P. van Duijnhoven, Wim J. M. van de Ven, Bruce G. Jenks, Eric W. Roubos, and Gerard J. M. Martens

15648 The roles of tyrosines 24, 31, and 60 in the high affinity binding of insulin-like growth factor-I to the type 1 insulin-like growth factor receptor.

Marvin L. Bayne, Joy Applebaum, Gary G. Chicchi, Rob- ert E. Miller, and Margaret A. Cascieri

15653 Class F Thy-l-negative murine lymphoma cells are deficient in ether lipid biosynthesis.

Victoria L. Stevens and Christian R. H. Raetz

15659 Gene cloning of chitinase A 1 from Bacillus circulans WL-12 revealed its evolutionary relationship to Serratia chitinase and to the type III homology units of fibronectin.

Takeshi Watanabe, Kazushi Suzuki, Wataru Oyanagi, Koji Ohnishi, and Hirosato Tanaka

15666 The R-state proinsulin and insulin hexamers mimic the carbonic anhydrase active site.

Mark L. Brader, Niels C. Kaarsholm. and Michael F. Dunn

15671 Mechanism of dioxygen formation catalyzed by va- nadium bromoperoxidase. Steady state kinetic analysis and comparison to the mechanism of brom- ination.

Richard R. Everett, Helena S. Soedjak, and Alison Butler

15680 Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides.

Joaquim Trias and Hiroshi Nikaido

15685 Surface expression of mutated subunits of the high affinity mast cell receptor for IgE.

Nadine Varin-Blank and Henry Metzger

15695 Des-Met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor an- tagonists, partial agonists, or agonists.

Lu-Hua Wang, David H. Coy, John E. Taylor, Ning-Yi Jiang, Jacques-Pierre Moreau, Shih Che Huang, Harold Frucht, Bassam M. Haffar, and Robert T. Jensen

15704 Protein kinase C heterogeneity in GH,C1 rat pitui- tary cells. Characterization of a Ca’+-independent phorbol ester receptor.

Susan Kiley, Dick Schaap, Peter Parker, Ling-Ling Hsieh, and Susan Jaken

iv

15713 Quantitative analysis of the endocytic system in- volved in hormone-induced receptor internaliza- tion.

Kirk A. Lund, Lee K. Opresko, Cindy Starbuck, Brenda J. Walsh, and H. Steven Wiley

15823

15832

Role of ceramide as a lipid mediator of la,26-dihy- droxyvitamin Da-induced HL-60 cell differentia- tion.-

Toshiro Okazaki, Alicia Bielawska, Robert M. Bell, and Yusuf A. Hannun

15724

15731

15738

15744

15750

Mechanisms of the stimulation of insulin release by arginine-vasopressin in normal mouse islets.

Zhi-Yong Gao, Gisela Drews, Myriam Nenquin, Tim D. Plant, and Jean-Claude Henquin

Two distinct cystatin species in rice seeds with dif- ferent specificities against cysteine proteinases. Molecular cloning, expression, and biochemical studies on oryzacy&atin-II.

Hiroto Kondo, Keiko Abe, Ikuko Nishimura, Hirohito Watanabe, Yasufumi Emori, and Soichi Arai Divalent cation activation of galactosyltransferase

in native mammary Golgi vesicles. David L. Witsell, Clare E. Casey, and Margaret C. Neville

Selective adenosine release from human B but not T lymphoid cell line.

Jerzy Barankiewicz, Greg Ronlov, Roland Jimenez, and Harry E. Gruber

Isolation and characterization of a cDNA clone en- coding rat nucleoside diphosphate kinase.

Narimichi Kimura, Nobuko Shimada, Kohji Nomura, and Kazutada Watanabe

15838

15845

15850

Protein synthesis in yeast. Structural and func- tional analysis of the gene encoding elongation fac- tor 3.

Mark G. Sandbaken, John A. Lupisella, Beth Di- Domenico, and Kalpana Chakraburtty

Induction and superinduction of auxin-responsive mRNAs with auxin and protein synthesis inhibitors.

Antonio R. France, Melissa A. Gee, and Tom J. Guilfoyle

A fraction of CD3c subunits exists as disulfide- linked dimers in both human and murine T lympho- cytes.

Intragenic suppressors reveal long distance inter- actions between inactivating and reactivating amino acid replacements generating three-dimen- sional constraints in the structure of mitochondrial cytochrome b.

Jean-Paul di Rago, Pierre Netter, and Piotr P. Slonimski

Yong-Jiu Jin, Shigeo Koyasu, Philippe Moingeon, Ruth Steinbrich, George E. Tarr, and Ellis L. Reinherz

15854 Expression of human parathyroid hormone-(l-84) in Escherichia coli as a factor X-cleavable fusion protein. Tyrosyl free radical formation in the small subunit

of mouse ribonucleotide reductase. Ei-Zchiro Ochiai, Graham J. Mann, Astrid Grcislund, and

Lars Thelander

Orientation of retinal in bovine rhodopsin deter- mined by cross-linking using a photoactivatable an- alog of 11-cis-retinal.

Tomoko A. Nakayama and H. Gobind Khorana

Purification and complete amino acid sequence of a new type of sweet protein with taste-modifying ac- tivitv. curculin.

~~ -~” I ~~

Haruyuki Yamashita, Sarroch Theerasilp, Toshihiro Aiuchi, Kazuyasu Nakaya, Yasuharu Nakamura, and Yoshie Kurihara

Thomas J. Garde& David Rubin, Abdul-Badi Abou- Samra, Henry T. Keutmann, John T. Potts, Jr., Henry M. Kronenberg, and Samuel R. Nussbaum

15758

15762

15770

15860

15867

Protein kinase A phosphorylates retinal phosducin on serine 73 in situ.

Rehwa Ho Lee, Bruce M. Brown, and Richard N. Lolley

Amino acid and cDNA sequence of bovine phosdu- tin, a soluble phosphoprotein from photoreceptor cells.

Rehwa Ho Lee, Audree Fowler, James F. McGinnis, Richard N. Lolley, and Cheryl M. Craft

Characterization of novel sequences containing 3- O-sulfated glucosamine in glomerular basement membrane heparan sulfate and localization of sul- fated disaccharides to a peripheral domain.

Albert S. B. Edge and Robert G. Spiro

Intestinal lactase. Shift in intracellular processing to altered, inactive species in the adult rat.

Richard Quan, Nilda A. Santiago, Kenneth K. Tsuboi. and Gary M. Gray

Intestinal lactase in the neonatal rat. Maturational changes in intracellular processing and brush-bor- der degradation.

15874

15776

15782

Direct effects of radiation on the avidin-biotin sys- tem. Absence of energy transfer.

Ellis S. Kempner and Jay H. Miller

The activity of one soluble component of the cell- free NADPH:Oa oxidoreductase of human neutro- phils depends on guanosine 5’-0-(3-thio)triphos- phate.

Ben G. J. M. Bolscher, Simone W. Denis, Arthur J. Verhoeven, and Dirk Roos

15882

15889

15788 Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) tran- scriptional activity determined by a new method using transgenic mice to assay transcriptional activ- ity of an individual nuclear factor.

Cornelis L. Verweij, Cynthia Guidos, and Gerald R. Crab- tree

Ricardo 0. Castillo. Ann M. Reisenauer. Linda K. Kwong, Kenneth K. Tsuboi, Richard Quan, and Gary M. Gray -.

Modulation of Ca2+ release channel activity from sarcoplasmic reticulum by annexin VI (67-kDa cal- cimedin).

Mauricio Diaz-Mu&x, Susan L. Hamilton, Marcia A. Kaetzel, Parul Hazarika, and John R. Dedman

Mitochondrial creatine kinase from chicken brain. Purification, biophysical characterization, and gen- eration of heterodimeric and heterooctameric mol- ecules with subunits of other creatine kinase isoen- zymes.

15894

15796

15804

Formation and enzymatic properties of the UvrB- DNA complex.

David K. Orren and Aziz Sancar

Tertiary structure of oxidized flavodoxin from a eukaryotic red alga Chondrus crispus at 2.35- w resolution. Localization of charged residues and im- plication for interaction with electron transfer part- ners.

Keiichi Fukuyama, Sadao Wakabayashi, Hiroshi Mat- subara, and Lyndon J. Rogers

Markus Wyss, Jorg Schlegel, Peter James, Hans M. Eppenberger, and Theo Wallimann

15909

15920

Genes required for formation of the apoMoFe pro- tein of Klebsiella pneumoniae nitrogenase in Esch- erichia coli.

15813

15818

Cloning of ubiquitin activating enzyme from wheat and expression of a functional protein in Esche- richia coli.

Peggy M. Hatfield, Judy Callis, and Richard D. Vierstra

A retinoic acid-inducible mRNA from F9 teratocar- cinema cells encodes a novel protease inhibitor hom- ologue.

Sho- Ya Wang and Lorraine J. Gudos

Georgianna S. Harris, Theresa C. White, Janice E. Flory, and William H. Orme-Johnson

Species-specific substrate interaction of picornavi- rus 3C proteinase suballelic exchange mutants.

Mark A. Lawson, Bimalendu Dasmahapatra, and Bert L. Semler

v

15932 Complete and partial glycophospholipid anchors are found on a fusion protein consisting of luteinizing hormone B subunit followed by a carboxyl-terminal domain of Thy- 1.

David M. Kaetzel, Neena Singh, Giulia C. Kennedy, Jeffrey B. Virgin, George Farr, Yasuo Kitagawa, John H. Nilson, and Alan M. Tartakoff

15938 Distinct chromatographic forms of human hemi-my- eloperoxidase obtained by reductive cleavage of the dimeric enzyme. Evidence for subunit heterogene- ity.

Kathryn L. Taylor, Georgianna S. Guzman, Jan Pohl, and Joseph M. Kinkade, Jr.

15947 Proteoglycan biosynthesis by human corneas from patients with types 1 and 2 macular cornea1 dystro- phy.

Ronald J. Midura, Vincent C. Hascall, Donald K. MacCallum, Roger F. Meyer, Eugene J-M. A. Thonar, John R. Hassell, Clayton F. Smith, and Gordon K. Klintworth

I .5956 Isolation of two isoforms of a novel 15-kDa protein from rabbit polymorphonuclear leukocytes that modulate the antibacterial actions of other leuko- cyte proteins.

Chean Eng Ooi, Jerrold Weiss, Ofer Levy, and Peter Elsbach

15963 Enhanced phosphorylation of a coated vesicle poly- peptide in response to insulin stimulation of rat adipocytes.

Silvia Corvera and Renold J. Capocasale

15970 The structure and regulation of expression of the murine fast skeletal troponin C gene. Identification of a developmentally regulated, muscle-specific transcriptional enhancer.

Michael S. Parmacek, A. Resai Bengur, Anuradha J. Vora, and Jeffrey M. Letden

15977 The amyloid precursor protein of Alzheimer’s dis- ease is released by human platelets.

Ashley I. Bush, Ralph N. Martins, Baden Rumble, Robert Moir, Stephanie Fuller, Elizabeth Milward, Jon Currie, Davtd Ames, Andreas Weidemann, Peter Fischer, Gerd Multhaup, Konrad Beyreuther, and Colin L. Masters

15984

15991

15996

16004

16007

16012

16020

16025

Protein disulfide-isomerase in rat exocrine pan- creatic cells is exported from the endoplasmic retic- ulum despite possessing the retention signal.

Tamotsu Yoshimori, Toshihiko Semba, Hiroto Takemoto, Shigeo Akagi, Akitsugu Yamamoto, and Yutaka Tashiro

A possible role of the &subunit of (Na,K)-ATPase in facilitating correct assembly of the a-subunit into the membrane.

Shunsuke Noguchi, Ken Higashi, and Mosaru Kawa- mura

Primary structure of the yeast choline transport gene and regulation of its expression.

Jun-ichi Nikawa, Kohei Hosaka, Yuko Tsukagoshi, and Satoshi Yamashita

Extensive interference of DNA packaging processes affected by chemotherapeutic drugs.

Ziv Reich, Rodolfo Ghirlando, Talmon Arad, Sarah Wein- berger, and Abraham Minsky

Structural and functional characterization of a splicing mutation in the pro-a2(1) collagen gene of an Ehlers-Danlos type VII patient.

Domini i?

ue Weil, Marina D’Alessio, Francesco Ramirez, and Davt R. Eyre

Partial purification and characterization of the Ca2+-pumping ATPase of the liver plasma mem- brane.

Felix Kessler, Federico Bennardini, Oriol Baths, Joan Serratosa, Peter James, Ariel J. Caride, Paolo Gazzotti, John T. Penn&on, and Ernest0 Carafoli

Carotenoid desaturases from Rhodobacter capeula- tus and Neurospora crossa are structurally and functionally conserved and contain domains homol- ogous to flavoprotein disulfide oxidoreductases.

Glenn E. Bartle Thomas J. Schmidhauser, Charles Yanofsky, and Pab o A. Scolnik ?

ADDITIONS AND CORRECTIONS

Thrombospondin forms complexes with single- chain and two-chain forms of urokinase. Vol. 265 (1990) 11289-11294.

Roy L. Silverstein, Ralph L. Nachman, Ralph Pannell, Victor Gurewich, and Peter C. Ha@

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The Journal of Biological Chemistry (ISSN 0021-9258) is published three times per month by the American Society for Biochemistry and Molecular Biology, Inc., 428 East Preston Street, Baltimore, MD 21202, U.S.A. Volume 265 for 1990: United States, $510; other coun- tries, $635. Single copy: United States, $19.00; other countries, $22.00. Special subscription rates are available to members, graduate stu- dents, and postdoctoral fellows for personal use only. Qualifying forms are available from the ASBMB Office, 9650 Rockville Pike, Bethesda, MD 20814. Second class postage paid at Baltimore, MD 21202, U.S.A. and at additional mailing offices. Send address changes to The Jour- nal of Biological Chemistry at 428 East Preston Street, Baltimore, MD 21202, U.S.A.

Vol. 265, No. 26 The Journal of Biological Chemistry September 15, 1990

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CONTENTS Arranged by Subject Categories

MINIREVIEW 15418

Mutations that alter the primary structure of type I collagen. The perils of a system for generating large structures by the principle of nucleated growth.

Darwin J. Prockop

CARBOHYDRATES, LIPIDS, AND OTHER NATURAL PRODUCTS

Biosynthesis of heparin. 0-Sulfation of D-glucu- ronic acid units.

Marion Kusche and Vlj Lindahl

Isolation and characterization of the glycosamino- glycan component of rabbit thrombomodulin pro- teoglycan.

Marie-Claude Bourin, Evy Lundgren-Akerlund, and Ulf Lindahl

Synthesis of platelet-activating factor by endothe- lial cells. The role of G proteins.

Ralph E. Whatley, Dan F. Fennell, Jeffery A. Kurrus, Guy A. Zimmerman, Thomas M. McIntyre, and Stephen M. Prescott

Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.

Alan D. Elbein, Joseph E. Tropea, Mike Mitchell, and Gur P. Kaushal

Molecular cloning and heterologous expression of N-glycosidase F from Flavobacterium meningosep- ticum.

Daniela Lemp, Anton Haselbeck, and Franz Klebl

Characterization of novel sequences containing 3- O-sulfated glucosamine in glomerular basement membrane heparan sulfate and localization of sul- fated disaccharides to a peripheral domain.

Albert S. B. Edge and Robert G. Spiro

Proteoglycan biosynthesis by human corneas from patients with types 1 and 2 macular cornea1 dystro- ihy.

Ronald J. Midura, Vincent C. Hascall, Donald K. MacCallum, Roger F. Meyer, Eugene J.-M. A. Thonar, John R. Hassell, Clayton F. Smith, and Gordon K. Klintworth

CELL BIOLOGY AND METABOLISM 15653

Cyclic AMP induces insulin-like growth factor I synthesis in osteoblast-enriched cultures.

Thomas L. McCarthy, Michael Centrella, and Ernest0 Canalis

15685

A novel metabolic form of the 32kDa-Dl protein in the grana-localized reaction center of photosystem II.

Franklin E. Callahan, Maria L. Ghirardi, Sudhir K. Sopory, Arkesh M. Mehta, Marvin Edelman, and Autar K. Mattoo

15695

Expression of mRNA coding for kidney and red cell water channels in Xenopus oocytes.

Rubin Zhang, Katherine A. Logee, and A. S. Verkman 15713

Derivatives of somatic cell hybrids which carry the human gene locus for nephrogenic diabetes insipi- dus (NDI) express functional vasopressin renal Vz- type receptors.

David A. Jans, Bernard A. van Oost, Hilger H. Ropers, and Falk Fahrenholz

15724

Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate.

Kathryn A. Brozek and Christian R. H. Raetz

15441

15471

15489

15506

15511

15544

15577

15584

15738

A diacylglycerol kinase inhibitor, R 59 022, poten- tiates superoxide anion production and 46-kDa pro- tein phosphorylation in guinea pig polymorphonu- clear leukocytes.

Toshiaki Ohtsuka, Masanori Hiura, Kiyomi Yoshida, Naoki Okamura, and Sadahiko Zshibashi

Sodium fluoride prevents receptor- and protein ki- nase C-mediated activation of the human platelet Na+/H+ exchanger without inhibiting its basic pH,- regulating activity.

Winfried Siffert, Karl H. Jakobs, and Jan Willem N. Akkerman

Nerve growth factor and fibroblast growth factor selectively activate a protein kinase that phospho- rylates high molecular weight microtubule-associ- ated proteins. Detection, partial purification, and characterization in PC12 cells.

Hensin Tsao, John M. Aletta, and Lloyd A. Greene

Adipose conversion of 3T3-Ll cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP.

Wilfried Schmidt, Gisela Pbll-Jordan, and Georg L$fler

Evaluation of the double-auantum filter for the measurement of intracellular sodium concentration.

Robert B. Hutchison, Deepak Malhotra, R. Edward Hendrick, Laurence Ghan, and Joseph I. Shapiro

Post-translational addition of an arginine moiety to acidic NH2 termini of proteins is required for their recognition by ubiquitin-protein ligase.

Sarah Eliaa and Aaron Ciechanover

Pulmonary fibroblasts: an in vitro model of emphy- sema. Regulation of elastin gene expression.

Judith Ann Foster, Celeste B. Rich, and Mary F. Miller

The phagocyte 47-kilodalton cytosolic oxidase pro- tein is an early reactant in activation of the respi- ratory burst.

Michael E. Kleinberg, Harry L. Malech, and Daniel Rotrosen

Localization of functional domains of the CAMP che- motactic receptor of Dictyostelium discoideum.

Yonping Tao and Claudette Klein

Class F Thy-l-negative murine lymphoma cells are deficient in ether lipid biosynthesis.

Victoria L. Stevens and Christian R. H. Raetz

Surface expression of mutated subunits of the high affinity mast cell receptor for IgE.

Nadine Varin-Blank and Henry Metzger

Des-Met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor an- tagonists, partial agonists, or agonists.

Lu-Hua Wang, David H. Coy, John E. Taylor, Ning-Yi Jiang, Jacques-Pierre Moreau, Shih Che Huang, Harold Frucht, Bassam M. Haffar, and Robert T. Jensen

Quantitative analysis of the endocytic system in- volved in hormone-induced receptor internaliza- tion.

Kirk A. Lund, Lee K. Opresko, Cindy Starbuck, Brenda J. Walsh, and H. Steven Wiley

Mechanisms of the stimulation of insulin release by arginine-vasopressin in normal mouse islets.

Zhi-Yong Gao, Gisela Drews, Myriam Nenquin, Tim D. Plant, and Jean-Claude Henquin

Selective adenosine release from human B but not T lymphoid cell line.

Jerzy Barankiewicz, Greg Ronlov, Roland Jimenez, and Harry E. Gruber

l Indicates a Communication

vi

15823

15932

15956

15963

15977

15984

015361

015368

15464

15617

15671

15704

15731

15758

Role of ceramide as a lipid mediator of la,25-dihy- droxyvitamin Ds-induced HL-60 cell differentia- tion.

Toshiro Okazaki, Alicja Bielawska, Robert M. Bell, and Yusuf A. Hannun

Complete and partial glycophospholipid anchors are found on a fusion urotein consisting of luteinizing hormone fl subunit hollowed by a ca;boxyl-termina domain of Thv- 1.

David M. Kaetzel, Neena Singh, Giulia C. Kennedy, Jeffrey B. Virgin, George Farr, Yasuo Kitagawa, John H. Nilson, and Alan M. Tartakoff

Isolation of two isoforms of a novel 15-kDa protein from rabbit polymorphonuclear leukocytes that modulate the antibacterial actions of other leuko- cyte proteins,

Chean Eng Ooi, Jerrold Weiss, Ofer Levy, and Peter ELsbach

Enhanced phosphorylation of a coated vesicle poly- peptide in response to insulin stimulation of rat adipocytes.

Silvia Corvera and Renold J. Capocasale

The amyloid precursor protein of Alzheimer’s dis- ease is released by hum& platelets.

Ashley I. Bush, Ralph N. Martins, Baden Rumble, Robert Moir, Stephanie Fuller, Elizabeth Milward, Jon Currie, David Ames, Andreas Weidemann, Peter Fischer, Gerd Multhaup, Konrad Beyreuther, and Colin L. Masters

Protein disulfide-isomerase in rat exocrine pan- creatic cells is exported from the endoplasmic retic- ulum despite possessing the retention signal.

Tamotsu Yoshimori, Toshihiko Semba, Hiroto Takemoto, Shigeo Akagi, Akitsugu Yamamoto, and Yutaka Tashiro

ENZYMOLOGY

Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity.

William W. WelLs, Dian Peng Xu, Yanfeng Yang, and Pamela A. Rocque

Inhibition by substrate of fructose 1,6-bisphospha- tase purified from rat kidney cortex. Calculation of the kinetic constants of the enzyme.

Albert0 M. Vargas, Maria M. Sola, and Michel Bounias

The effects of NADPH and 3-hydroxy-3-methylglu- taryl-CoA on the thiol/disulfide redox behavior of rat liver microsomal 3-hydroxy-3-methylglutaryl- CoA reductase.

Roseann E. Cappel and Hiram F. Gilbert

Hepatic 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase. Use of site-directed mutagenesis to evaluate the roles of His-258 and His-392 in catal- ysis.

Albert Tauler, Kai Lin, and Simon J. Pilkis

Mechanism of dioxygen formation catalyzed by va- nadium bromoperoxidase. Steady state kinetic analysis and comparison to the mechanism of brom- ination.

Richard R. Everett, Helena S. Soedjak, and Alison Butler

Protein kinase C heterogeneity in GH& rat pitui- tary cells. Characterization of a Ca’+-independent phorbol ester receptor.

Susan Kiley, Dick Schaap, Peter Parker, Ling-Ling Hsieh, and Susan Jaken

Divalent cation activation of galactosyltransferase in native mammary Golgi vesicles.

David L. Witself, Glare E. Casey, and Margaret C. Neville

Tyrosyl free radical formation in the small subunit of mouse ribonucleotide reductase.

Ei-lchiro Ochiai, Graham J. Mann, Astrid Griislund, and

15782

15796

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15860

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15889

15900

16025

l 15371

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vii

The activity of one soluble component of the cell- free NADPH:O? oxidoreductase of human neutro- phils depends on guanosine 5’-0-(3-thio)triphos- phate.

Ben G. J. M. Bolscher, Simone W. Denis, Arthur J. Verhoeven, and Dirk Roos

Formation and enzymatic properties of the UvrB* DNA complex.

David K. Orren and Aziz Sancar

Two distinct cystatin species in rice seeds with dif- ferent specificities against cysteine proteinases. Molecular cloning, expression, and biochemical studies on oryzacystatin-II.

Hiroto Kondo, Keiko Abe, Ikuko Nishimura, Hirohito Watanabe, Yasufumi Emori, and Soichi Arai

Protein kinase A phosphorylates retinal phosducin on serine 73 in situ.

Rehwa Ho Lee, Bruce M. Brown, and Richard N. Lolley

Intestinal lactase. Shift in intracellular processing to altered, inactive species in the adult rat.

Richard Quan, Nilda A. Santiago, Kenneth K. Tsuboi, and Gary M. Gray

Intestinal lactase in the neonatal rat. Maturational changes in intracellular processing and brush-bor- der degradation.

Ricardo 0. Castillo, Ann M. Reisenauer, Linda K. Kwong, Kenneth K. Tsuboi, Richard Quan, and Gary M. Gray

Mitochondrial creatine kinase from chicken brain. Purification. biouhvsical characterization. and een- eration of heterodimeric and heterooctameric mol- ecules with subunits of other creatine kinase isoen- zymes.

Markus Wyss, J6rg Schlegel, Peter James, Hans M. Eppenberger, and Theo Wallimann

Thrombospondin forms complexes with single- chain and two-chain forms of urokinase. Vol. 265 (1990) 11289-11294.

Roy L. Silverstein, Ralph L. Nachman, Ralph Pannell, Victor Gurewich, and Peter C. Harpel

MEMBRANES AND BIOENERGETICS

Vasoactive intestinal peptide, a singlet oxygen quencher.

Bibhu R. Misra and Hara P. Misra

Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat.

William L. Rumsey, Cindy Schlosser, E. Matti Nuutinen, Michael Robiolio, and David F. Wilson

Appendix. Oxygen transport to respiring myocytes. Keith E. Dionne

An ATP-modulated specific association of glycer- aldehyde-3-phosphate dehydrogenase with human erythrocyte glucose transporter.

Mohsen Lachaal, Charles J. Berenski, John Kim, and Chan Y. Jung

Molecular cloning of cDNA encoding a 55-kDa mul- tifunctional thvroid hormone bindine urotein of skeletal musclesarcoplasmic reticul&. -

Larry Fliegel, Elizabeth Newton, Kimberly Burns, and Marek Michalak

Effects of phosphate and hydrophobic molecules on two mutations in the .&strand sector of the H+- ATPase from the yeast plasma membrane.

Andre! Goffeau and Leopold0 de Meis

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon, TnlO. The role of the conserved dipeptide, Sersa-Asp”, in tetracycline transport.

Akihito Yamaguchi, Nobukazu Ono, Takaaki Akasaka, Takato Noumi, and Tetsuo Sawai Lars Thelander

l Indicates a Communication

. . . VU1

15531

15564

15590

15623

15632

15680

15894

15991

16012

A structural change in the Neurospora plasma membrane [H+JATPase induced by ~-ethylmaleim- ide.

Amy Chang and Carolyn W. Slayman

Characterization of high affinity binding sites for charybdotoxin in synaptic plasma membranes from rat brain. Evidence for a direct association with an inactivating, voltage-dependent, potassium chan- nel.

Jeslis Vdzquez, Pamela Feigenbaum, V. Frank King, Gregory J. Kaczorowski, and Maria L. Garcia

Calcium binding to the H+,K’-ATPase. Evidence for a divalent cation site that is occupied during the catalytic cycle.

John Mendlein, Michael L. Ditmars, and George Sachs

Transmembrane movement of heme. W. Richard Light III and John S. Olson

The effects of lipid composition on the rate and extent of heme binding to membranes.

W. Richard Light III and John S. Olson

Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides.

Joaquim Trias and Hiroshi Nikaido

Modulation of Caz+ release channel activity from sarcoplasmic reticulum by annexin VI (67-kDa cal- cimedin) .

Mauricio Diaz-Mu&x, Susan L. Hamilton, Marcia A. Kaetzel, Parul Hazarika, and John R. Dedman

A possible role of the b-subunit of (Na,K)-ATPase in facilitating correct assembly of the a-subunit into the membrane.

Shunsuke Noguchi, Ken Higashi, and Masaru Kawa- mura

Partial purification and characterization of the Ca’+-pumping ATPase of the liver plasma mem- brane.

Felix Kessler, Federico 3ennardini, Oriol Baths, Joan Serratosa, Peter James, Ariel J. Caride, Paolo Gazzotti, John T. Pen&ton, and Ernest0 Carafoli

NUCLEIC ACIDS, PROTEIN SYNTHESIS, AND MOLECULAR GENETICS

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15611

Rapid induction of thymosin p4 in concanavalin A- stimulated thymocytes by translational control.

Bernd Schobitz, Roland Netzker, Ewald Hannappel, and Karl Brand

Gene sequence and analysis of hsp30, a small heat shock orotein of Neurosnora crassa which associ- ates with mitochondria. *

Nora Plesofsky- Vig and Robert Brambl

A transcriptional enhancer essential for the expres- sion of the rat cholecystokinin gene contains a se- quence identical to the -286 element of the human c-fos gene.

Randy S. Haun and Jack E. Dixon

Gene-enzyme refationship in the sulfate assimila- tion pathway of SaccFLaromyces cerevisiae. Study of the 3‘-phosphoadenylylsulfate reduetase strue- tural gene.

Dominique Thomas, Regine Barbey, and Yolande Surdin-Kerjan

Cloning and expression of the human SlOOfi gene. Robert J. Allore, William C. Friend, David O’Hanlon,

Karen M. Neilson, Reuben Baumal, Robert J. Dunn, and Alexander Marks

Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissues in vivo.

Paul H. A. Quan, C. Maria van den Hoogen, Jan H. Verheijen, Teresa Pa&o, Ron Zeheb, Thomas D. Gelehrter, Theo J. C. van Berkel, Johan Kuiper, and Jef J. Emeis

Structure of the human laminin Bl chain gene. Reetta Vuolteenaho, Louise T. Chow, and Karl

T~ggv~~on

15659

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15750

15788

15813

15818

15838

15845

15854

15909

15920

15970

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16004

The neuroendoerine polypeptide 7B2 is a precursor protein.

Torik A. Y. Ayo~i, Hans L. P, van ~u~nhoven, Wim J. M. van de Ven, Bruce G. Jenks, Eric W. Roubos, and Gerard J. M. Martens

Gene clonins of chitinase Al from Bacillus circulans WL-12 revealed its evolutionary relationship to Serratia chitinase and to the type III homology units of fibronectin.

Takeshi Watanabe, Kazushi Suzuki, Wataru Oyanagi, Koji Ohnishi, and Hirosato Tanaka

Isolation and characterization of a cDNA clone en- coding rat nucleoside diphosphate kinase.

Narimichi Kimura, Nobuko Shimada, Kohji Nomura, and Kazutada Watanabe

Intragenic suppressors reveal long distance inter- actions between inactivating and reactivating amino acid replacements generating three-dimen- sional constraints in the structure of mitochondrial eytochrome b.

Jean-Paul di Rago, Pierre Netter, and Pi&r P. S~nimski

Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) tran- scriptional activity determined by a new method using transgenic mice to assay transcriptional activ- ity of an individual nuclear factor.

Cornelis L. Verweij, Cynthia Guidos, and Gerald R. Crab- tree

Cloning of ubiquitin activating enzyme from wheat and expression of a functional protein in Esche- richia coli.

Peggy M. Hatfield, Judy Callis, and Richard D. Vierstra

A retinoic acid-inducible mRNA from FQ teratocar- cinema cells encodes a novel protease inhibitor hom- ologue.

Sho- Ya Wang and Lorraine J. Gudas

Protein synthesis in yeast. Structural and fune- tional analysis of the gene encoding elongation fac- tor 3.

Mark G. Sandbaken, John A. Lupisella, Beth Di- Domenico, and Kalpana C~kraburt~

Induction and superinduction of auxin-responsive mRNAs with auxin and protein synthesis inhibitors.

Antonio R. France, Melissa A. Gee, and Tom J. Guilfoyle

Expression of human parathyroid hormone-(l-84) in Escherichia coli as a factor X-cleavable fusion protein.

Thomas J. Gardella. David Rubin. Abdul-Badi Abou- Samra, Henry T. Keutmann, John T. ‘Potts, Jr., Henry M. Kronenberg, and Samuel R. Nussbaum

Genes required for formation of the apoMoFe pro- tein of Klebsiella pneumoniae nitrogenase in Esch- eriehia coti.

Georgianna S. Harris, Theresa C. White, Janice E. Flory, and William H. Orme-Joh~on

Species-specific. substrate interaction of picornavi- rus 3C proteinase suballelie exchange mutants.

Mark A. Lawson, Bima~ndu Dasmahapatra, and Bert L. Semler

The structure and regulation of expression of the murine fast skeletal trouonin C gene. Identification of a developmentally -regulated, muscle-specific transcriptional enhancer.

Michael S. Parmacek, A. Resai Bengur, Anuradha J. Vora, and Jeffrey M. Leiden

Primary structure of the yeast choline transport gene and regulation of its expression.

Jun-ichi Nikawa, Kohei Hosaka, Yuko Tsukagoshi, and Satoshi Yamashita

Extensive interference of DNA uackaaing processes affected by chemotherapeutic drugs. - - -

Ziv Reich, Rodolfo Ghirlando, Talmon Arad, Sarah Wein- berger, and Abraham Murky

ix

16007 Structural and functional characterization of a splicing mutation in the pro-cy2(1) collagen gene of an Ehlers-Danlos type VII patient.

Dominique Weil, Marina D’Alessio, Francesco Ramirez, and David R. Eyre

16020 Carotenoid desaturases from Rhodobacter capsula- tus and Neurospora crassa are structurally and functionally conserved and contain domains homol- ogous to flavoprotein disulfide oxidoreductases.

Glenn E. Bartley, Thomas J. Schmidhauser, Charles Yanofsky, and Pablo A. Scolnik

PROTEIN CHEMISTRY AND STRUCTURE

015365 Antimicrobial peptide, tachyplesin I, isolated from hemocytes of the horseshoe crab (Tachypleus tri- dentatus). NMR determination of the &sheet struc- ture.

Keiichi Kawano, Takashi Yoneya, Toshiyuki Miyata, Katsuhiro Yoshikawa, Fuminori Tokunaga, Yoshihiro Terada, and Sadaaki Iwanaga

*I5383 Characterization of a carbon monoxide complex of reduced dopamine /3-hydroxylase. Evidence for in- equivalence of the Cu(1) centers.

Ninian J. Blackburn, Trudie M. Pettingill, Karen S. Seagraves, and Ronald T. Shigeta

15481 Use of amber suppressors to investigate the ther- mostability of Bacillus licheniformis a-amylase. Amino acid replacements at 6 histidine residues reveal a critical position at His-133.

Nathalie Declerck, Philippe Joyet, Claude Gaillardin, and Jean-Michel Masson

15572 Carboxyl methylation and COOH-terminal process- ing of the brain G-protein y-subunit.

Peter S. Backlund, Jr., William F. Simonds, and Allen M. Spiegel

15638 Mutations in the aspartate receptor of Escherichia coli which affect aspartate binding.

Sherry L. Mowbray and Daniel E. Koshland, Jr.

15648

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15762

15770

15776

15804

15850

15867

15938

The roles of tyrosines 24, 3.1, and 60 in the high affinity binding of insulin-hke growth factor-I to the type 1 insulin-like growth factor rece tor.

Marvin L. Bayne, Joy Applebaum, Gary G. C !? Lccht, Rob- ert E. Miller, and Margaret A. CascLeri

The R-state proinsulin and insulin hexamers mimic the carbonic anhydrase active site.

Mark L. Brader, Niels C. Kaarsholm, and Michael F. Dunn

Orientation of retinal in bovine rhodopsin deter- mined by cross-linking using a photoactivatable an- alog of 1 I-cis-retinal.

Tomoko A. Nakayama and H. Gobind Khorana

Purification and complete amino acid se uence of a new type of sweet protein with taste-mo lfying ac- 8. tivity, curculin.

Haruyuki Yamashita, Sarroch Theerasil R

Toshihiro A&hi, Kazuyasu Nakaya, Yasuharu Na amura, and Yoshie Kurihara Direct effects of radiation on the avidin-biotin sys- tem. Absence of energy transfer.

Ellis S. Kempner and Jay H. Miller

Tertiary structure of oxidized flavodoxin from a eukaryotic red alga Chondrus crispus at 2.35- w resolution. Localization of charged residues and im- plication for interaction with electron transfer part- ners.

Keiichi Fukuyama, Sadao Wakabayashi, Hiroshi Mat- subara, and Lyndon J. Rogers

A fraction of CD3c subunits exists as disulfide- linked dimers in both human and murine T lympho- cytes.

Yong-Jiu Jin, Shigeo Koyasu, Steinbrich, George E. Tarr, and

Amino acid and cDNA sequence of bovine phosdu- tin, a soluble phosphoprotein from photoreceptor cells.

Rehwa Ho Lee, Audree Fowler, James F. McGinnis, Richard N. Lo&y, and Cheryl M. Craft

Distinct chromatographic forms of human hemi-m - eloperoxidase obtained by reductive cleavage oft x e dimeric enzyme. Evidence for subunit heterogene- ity.

Kathryn L. Taylor, Georgianna S. Guzman, Jan Pohl, and Joseph M. Kmkade, Jr.

l Indicates a Communication