The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT...

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The iGEM Jamboree at MIT

Transcript of The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT...

Page 1: The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley.

The iGEM Jamboree at MIT

Page 2: The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley.

iGEM 20045 teams

Page 3: The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley.

iGEM 200513 teams

Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley Davidson Harvard UCSF

Page 4: The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley.

Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley Davidson Harvard UCSF

iGEM 200513 teams

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iGEM 200632 teams

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Putting the “i” in iGEM

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200754 teams

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200884 teams

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2009112 teams

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Chemistry

Mathematics Computer Science

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How is synthetic biology well-suited for interdisciplinary research?

Environment Energy Medicine Technology

Creativity Flexibility

If you have a common interest, you can find a synthetic biology way to approach it!

Adaptability

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Synthetic Biology Project Exampleshttp://2010.igem.org/Main_Page

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highGEM

Greenfield Central High School, Greenfield, INRebecca Schinii [email protected]

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Ethics/ Human Practice

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Construct Version

Synthetic biology uses molecular methods to construct DNA-based devices to perform novel functions. Synthetic biologists design, model, and construct biological parts, devices and systems by engineering and modifying existing biological systems. For instance, synthetic biologists can produce microbes that make useful chemicals. Synthetic biology gives scientists the tools to build biological devices from smaller biological units in much the same way as an engineer constructs a building from smaller construction materials. Synthetic biology has the potential to develop technologies that could lead the way in the 21st century.

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Create Version

Synthetic biology uses molecular methods to create modified living organisms that have never existed before. These DNA-based devices perform new functions not found in nature. Synthetic biologists redesign and modify existing, natural biological systems. For instance, synthetic biologists can create new versions of microbes that make chemicals not naturally found in microbes. In many ways, synthetic biology allows scientists to redesign biological processes and create organisms not found in nature. Synthetic biology has the potential to develop technologies that could lead the way in the 21st century.

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Ethics and Word Choice

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Ethics and Word Choice

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Energy

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2008 Project by Harvard iGEM Team

http://2008.igem.org/Team:Harvard

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Shewanella oneidensis MR-1

Page 23: The iGEM Jamboree at MIT. iGEM 2004 5 teams iGEM 2005 13 teams Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley.
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Four 2009 iGEM Projects

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http://2009.igem.org/Team:HKU-HKBU

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http://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controller

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http://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controller

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Environment

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Edinburgh iGEM 2006

Awards: Best Real World Application, Best Poster

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Poison Water

• Arsenic poisoning affects 100 million people

• Serious in Bangladesh

• Wells tap sedimentary layer with Arsenic• 1 in 4 wells contaminated

• Testing methods expensive, require instruments and expertise

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Range of Outputs

If no arsenic is present: Urease raises the pH to 9-10

If 5 ppb arsenic is present: Repressor shuts down Urease, pH remains neutral, pH 7

If 20 ppb arsenic is present: LacZ produced, pH 4.5

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Technology

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http://parts.mit.edu/igem07/index.php/Peking

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Toggle Switch

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Toggle Switch

A B Output

0 0 1

0 1 0

1 0 0

1 1 0

NOR Logic Gate

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Toggle Switch

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Explore the 2010 iGEM Wiki

Google search iGEM 2010 (first hit)

http://2010.igem.org/Main_Page

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Go explore!!