The great tragedy of science—the The great tragedy of science—the slaying of a beautiful hypothesis by an slaying of a beautiful hypothesis by an

ugly fact.ugly fact.

Thomas Huxley (1825-1895)Thomas Huxley (1825-1895)

Cholesterol QuizCholesterol QuizTrue or FalseTrue or False

1. The lower your cholesterol, the healthier you 1. The lower your cholesterol, the healthier you will be.will be.

2. A healthy range of cholesterol is 0 -200.2. A healthy range of cholesterol is 0 -200.

3. Cholesterol helps protect against environ-3. Cholesterol helps protect against environ-mental toxins.mental toxins.

4. Cholesterol less than 150 significantly reduces 4. Cholesterol less than 150 significantly reduces your risk of heart disease.your risk of heart disease.

5. The use of Statin drugs has lowered the 5. The use of Statin drugs has lowered the incidence of heart disease.incidence of heart disease.

6. Oxidative stress and inflammation are the root 6. Oxidative stress and inflammation are the root cause of elevated LDL.cause of elevated LDL.

7. Your risk of death is two times higher with low 7. Your risk of death is two times higher with low cholesterol than it is with high cholesterol.cholesterol than it is with high cholesterol.

8. High insulin levels are a greater risk factor for 8. High insulin levels are a greater risk factor for CVD than high cholesterol.CVD than high cholesterol.

9. The optimal cholesterol level is 225.9. The optimal cholesterol level is 225.

10. Cholesterol is a stand-alone test that can be10. Cholesterol is a stand-alone test that can be

used to determine health and disease.used to determine health and disease.

Cholesterol QuizCholesterol Quiz (cont.)(cont.)

What Is CholesterolWhat Is Cholesterol??

Formed in the liver and synthesized in other Formed in the liver and synthesized in other cells.cells.

Byproduct of protein metabolism.Byproduct of protein metabolism.

Bonding oily fat (fat-soluble vitamins) to Bonding oily fat (fat-soluble vitamins) to nitrogen via oxidation forms cholesterol.nitrogen via oxidation forms cholesterol.

Cholesterol then transposes it into a Cholesterol then transposes it into a lubricator, a hormone, antibody or enzyme.lubricator, a hormone, antibody or enzyme.

Serum CholesterolSerum Cholesterol

Total amount of cholesterol that is being Total amount of cholesterol that is being transported aboard the various lipoproteins.transported aboard the various lipoproteins.

Serves as a rendezvous point for antioxidants Serves as a rendezvous point for antioxidants and oxysterols.and oxysterols.

Serves as a colloidal stabilizer.Serves as a colloidal stabilizer.

What Is Cholesterol Used ForWhat Is Cholesterol Used For?? Bile production - 80% of cholesterol forms Bile production - 80% of cholesterol forms

cholic acid.cholic acid.

Hormone production and transportation.Hormone production and transportation.

Source of energy along with glucose.Source of energy along with glucose.

Production of cell membranes.Production of cell membranes.

Makes corneum of the skin to prevent water Makes corneum of the skin to prevent water loss.loss.

Plays a role in the immune defense system.Plays a role in the immune defense system.

LipoproteinsLipoproteins

Low Density Low Density Lipoproteins (LDL)Lipoproteins (LDL)

Rich in cholesterol Rich in cholesterol and carry someand carry some triglyceridestriglycerides Repair in the bodyRepair in the body Engulf toxins and then Engulf toxins and then

store in tissue cellsstore in tissue cells

High Density High Density Lipoproteins (HDL)Lipoproteins (HDL)

Rich in triglycerides Rich in triglycerides and carry some fatand carry some fat

Hormone productionHormone production Engulf toxins and Engulf toxins and

then store in tissue then store in tissue cellscells

At any one time the body can dictate the percentage of LDL vs. HDL

Saturated Fat Has No Impact Saturated Fat Has No Impact on LDL Levelson LDL Levels

Fact one: The liver does not use fats, Fact one: The liver does not use fats, saturated, or otherwise to make cholesterol.saturated, or otherwise to make cholesterol.

Fact two: The liver does not make LDL, it Fact two: The liver does not make LDL, it makes VLDL.makes VLDL.

Fact three: VLDL is converted to LDL through Fact three: VLDL is converted to LDL through triglyceride loss.triglyceride loss.

Fact four: VLDL levels and LDL levels are Fact four: VLDL levels and LDL levels are totally unrelated.totally unrelated.

www.redflagsweekly.com/kendrick/2002_dec12.htmlwww.redflagsweekly.com/kendrick/2002_dec12.html

The AnswersThe Answers

1. 1. The lower your cholesterol, the The lower your cholesterol, the healthier you will behealthier you will be..

European Heart JournalEuropean Heart JournalPublished 3 year study 11,500 patientsPublished 3 year study 11,500 patients

– Increase in lung cancer.Increase in lung cancer.– Increase in other cancers.Increase in other cancers.– Higher risk of cardiac death.Higher risk of cardiac death.– Erectile dysfunction and infertility.Erectile dysfunction and infertility.– Loss of memory and mental focus.Loss of memory and mental focus.

European Heart Journal 1997, 18, 52-59European Heart Journal 1997, 18, 52-59

1. 1. The lower your cholesterol, the The lower your cholesterol, the healthier you will behealthier you will be..

Swedish ResearcherSwedish Researcher

– Individuals with low cholesterol suffer from Individuals with low cholesterol suffer from frequent and severe infections.frequent and severe infections.

– Individuals with high cholesterol had a lower Individuals with high cholesterol had a lower mortality than the average population.mortality than the average population.

Uffe Ravnskov, MD, PhD, independent researcherUffe Ravnskov, MD, PhD, independent researcher

Magle Stora Kyrkogata 9, S-223250 Lund, SwedenMagle Stora Kyrkogata 9, S-223250 Lund, Sweden

2. 2. A healthy range of cholesterol A healthy range of cholesterol is 0-200is 0-200..

If your cholesterol was 0 you would be If your cholesterol was 0 you would be dead.dead.

Cancer risk for cholesterol levels:Cancer risk for cholesterol levels:

– Lowest risk >240 Lowest risk >240 – Average risk 195-210Average risk 195-210– Increased risk <190Increased risk <190– High < 160High < 160– Highest < 140Highest < 140

3. 3. Cholesterol helps protect Cholesterol helps protect against environmental toxinsagainst environmental toxins..

University San Diego School of Medicine Study University San Diego School of Medicine Study showed:showed:

– High cholesterol can be protective against High cholesterol can be protective against environmental toxins rather than harmful.environmental toxins rather than harmful.

– Low cholesterol is a risk factor for heart Low cholesterol is a risk factor for heart arrhythmias.arrhythmias.

High cholesterol readings are associated with High cholesterol readings are associated with protection from neurotoxins as well as cancer protection from neurotoxins as well as cancer protection.protection.

4.4. Cholesterol less than 150 Cholesterol less than 150 significantly reduces your risk significantly reduces your risk

of heart diseaseof heart disease..

Journal of American Medical Association 30 years Journal of American Medical Association 30 years of follow-up from the Framingham Study:of follow-up from the Framingham Study:

– No correlation between high cholesterol and No correlation between high cholesterol and mortality, but correlation between low cholesterol mortality, but correlation between low cholesterol and mortality.and mortality.

– CVD death rates increased 14% for every 1 mg/dl CVD death rates increased 14% for every 1 mg/dl drop in total cholesterol per year.drop in total cholesterol per year.

Anderson KM. Cholesterol and Mortality, 30 years of Follow-up from the Anderson KM. Cholesterol and Mortality, 30 years of Follow-up from the Framingham study. JAMA 1987 Apr 24;257(16):2176-80 Framingham study. JAMA 1987 Apr 24;257(16):2176-80

4. 4. Cholesterol less than 150 Cholesterol less than 150 significantly reduces your risk of significantly reduces your risk of

heart diseaseheart disease..Journal of Cardiac Failure Paper on Low CholesterolJournal of Cardiac Failure Paper on Low Cholesterol

– Analysis of 1,134 patients with heart disease Analysis of 1,134 patients with heart disease – Low cholesterol was associated with worse Low cholesterol was associated with worse

outcomes in heart failure patients and impaired outcomes in heart failure patients and impaired survival ratessurvival rates

– Elevated cholesterol was not associated with Elevated cholesterol was not associated with hypertension, diabetes or coronary heart disease.hypertension, diabetes or coronary heart disease.

– Horwich TB. Et.al. Low Serum Total Cholesterol is Horwich TB. Et.al. Low Serum Total Cholesterol is Associated with Marked Increase in Mortality in Associated with Marked Increase in Mortality in Advanced Heart Failure.Advanced Heart Failure.

Journal of Cardiac Failure 2002 Aug;8(4):216-214Journal of Cardiac Failure 2002 Aug;8(4):216-214

4. 4. Cholesterol less than 150 Cholesterol less than 150 significantly reduces your risk of significantly reduces your risk of

heart diseaseheart disease..

Japanese StudyJapanese Study

– Found as cholesterol levels went up Found as cholesterol levels went up death rates from CHD went downdeath rates from CHD went down

Okayama A., Marmot MG Int. J Epidemiol Dec 1993Okayama A., Marmot MG Int. J Epidemiol Dec 1993

4. 4. Cholesterol less than 150 Cholesterol less than 150 significantly reduces your risk of significantly reduces your risk of

heart diseaseheart disease..

Low cholesterol readings are associated with:Low cholesterol readings are associated with:

– Increased risk for cancerIncreased risk for cancer– Increased risk for strokeIncreased risk for stroke– Increased risk for suicideIncreased risk for suicide– Increased risk for symptoms from exposure to:Increased risk for symptoms from exposure to:

NeurotoxinsNeurotoxins Mercury and other heavy metalsMercury and other heavy metals Cyclosporin Cyclosporin

5. 5. The use of statin drugs The use of statin drugs lowers your risk of heart lowers your risk of heart

diseasedisease..

Despite successful attempts to lower Despite successful attempts to lower cholesterol with statin drugs, the death rate cholesterol with statin drugs, the death rate from heart disease has not changed in 75 from heart disease has not changed in 75 years.years.

And mortality from heart disease is more than And mortality from heart disease is more than double what is was in 1996.double what is was in 1996.

Uri Goldbourt. Arteriosclerosis Vol 10. No 4. July/August Uri Goldbourt. Arteriosclerosis Vol 10. No 4. July/August 19901990

Adverse Effects of StatinsAdverse Effects of Statins– Known carcinogens in experimental animals in Known carcinogens in experimental animals in

doses approximate to those given to patients. doses approximate to those given to patients. – Increase risk of polyneuropathy 14 times.Increase risk of polyneuropathy 14 times.– Deplete CoQ10, lower antioxidant levels.Deplete CoQ10, lower antioxidant levels.– Liver dysfunction. Liver dysfunction. – Muscle pain. Muscle pain. – Memory loss, lack of concentration and global Memory loss, lack of concentration and global

amnesia.amnesia.– Insomnia, weakness and fatigue.Insomnia, weakness and fatigue.– Erectile dysfunction.Erectile dysfunction.– Difficulty in managing diabetes, raises insulin levels.Difficulty in managing diabetes, raises insulin levels.

Total annual sales of statins = $14 billionTotal annual sales of statins = $14 billion

CoQ10 and Statin DrugsCoQ10 and Statin Drugs Statin drugs block the body’s ability to create Statin drugs block the body’s ability to create

CoQ10, and can lead to myopathy. Without CoQ10, and can lead to myopathy. Without CoQ10 your heartbeat would come to a CoQ10 your heartbeat would come to a screeching halt.screeching halt.

Drug companies knew about this danger 13 Drug companies knew about this danger 13 years ago when they introduced the first statin years ago when they introduced the first statin drugs.drugs.

The manufacturer of the second largest selling The manufacturer of the second largest selling statin received two patents from the U.S. statin received two patents from the U.S. government for a Statin-CoQ10 combination. government for a Statin-CoQ10 combination. These patent numbers are 4,929,437 and These patent numbers are 4,929,437 and 4,933,165.4,933,165.

In its patent applications this drug company In its patent applications this drug company pointed out that statin drugs can lower the pointed out that statin drugs can lower the body’s levels of CoQ10, that this can cause body’s levels of CoQ10, that this can cause myopathy, and that taking CoQ10 with the myopathy, and that taking CoQ10 with the statin drugs can counteract this effect.statin drugs can counteract this effect.

For some reason, the company never For some reason, the company never marketed or publicized this statin/CoQ10 marketed or publicized this statin/CoQ10 combination.combination.

If your taking statin drugs, you should take at If your taking statin drugs, you should take at least 50mg a day of CoQ10. Then, you should least 50mg a day of CoQ10. Then, you should consider weaning yourself off these drugs, consider weaning yourself off these drugs, under a doctor’s supervision.under a doctor’s supervision.

6.6. Oxidative stress and Oxidative stress and inflammation are the root inflammation are the root

cause of elevated LDLcause of elevated LDL.. Artery walls must be damaged before arterial Artery walls must be damaged before arterial

plaque is formed.plaque is formed.

LDL does not damage the endothelium (artery LDL does not damage the endothelium (artery lining), oxidation does.lining), oxidation does.

LDL tries to repair the damage.LDL tries to repair the damage. Cholesterol raises as a response to Cholesterol raises as a response to

inflammation to protect the nerves and brain inflammation to protect the nerves and brain against exposure to fat soluble toxins and against exposure to fat soluble toxins and heavy metalsheavy metals

6. 6. Oxidative stress and Oxidative stress and inflammation are the root cause inflammation are the root cause

of elevated LDLof elevated LDL..

If you douse yourself in gasoline, will you burst If you douse yourself in gasoline, will you burst into flames?into flames?

A group consuming American diet had lower A group consuming American diet had lower antioxidant levels versus the Mediterranean antioxidant levels versus the Mediterranean diet which had increased antioxidant levels.diet which had increased antioxidant levels.

Mediterranean's had one-third the rate of heart Mediterranean's had one-third the rate of heart attacks that Americans did. attacks that Americans did.

Leon Study, Circulation, 1999, 99. Pg 779.Leon Study, Circulation, 1999, 99. Pg 779.

7. 7. Your risk of death is two times Your risk of death is two times higher with low cholesterol than it higher with low cholesterol than it

is with high cholesterolis with high cholesterol.. Study with 11,500 patients showed that the risk Study with 11,500 patients showed that the risk

of death in the low cholesterol group (160mg/dl of death in the low cholesterol group (160mg/dl and below) was 2.27 times higher than those and below) was 2.27 times higher than those with high cholesterol.with high cholesterol.

Most common cause of death in low cholesterol Most common cause of death in low cholesterol patients was cancer.patients was cancer.

European Heart Journal (1997) 18,52-59.European Heart Journal (1997) 18,52-59.

8. 8. High insulin levels are a greater High insulin levels are a greater risk factor for CVD than high risk factor for CVD than high

cholesterolcholesterol..

High levels of the stress hormone cortisol High levels of the stress hormone cortisol along with high insulin levels creates the along with high insulin levels creates the metabolic state that causes atherosclerotic metabolic state that causes atherosclerotic plaque development.plaque development.

The French Paradox by Hugh Tunstall-Pedoe 1978The French Paradox by Hugh Tunstall-Pedoe 1978

Triglycerides/HDL = >3 is an indicator of Triglycerides/HDL = >3 is an indicator of hyperinsulinemiahyperinsulinemia

9.9. The optimal cholesterol The optimal cholesterol level is 225level is 225..

According to the latest lab values, the new According to the latest lab values, the new range is 0 – 169.range is 0 – 169.

If your cholesterol was 0 you would be If your cholesterol was 0 you would be dead.dead.

Normal suggestion is 175 – 275.Normal suggestion is 175 – 275.

10. 10. Cholesterol is a stand-alone Cholesterol is a stand-alone test that can be used to determine test that can be used to determine

health and diseasehealth and disease..

Cholesterol is affected by many organs and Cholesterol is affected by many organs and glands and in itself is not a reliable indicator glands and in itself is not a reliable indicator as to what is going on in the body as a whole.as to what is going on in the body as a whole.

High CholesterolHigh Cholesterol

Inflammatory Response.Inflammatory Response.

Protects the nerves and brain against Protects the nerves and brain against exposure to fat-soluble toxins and heavy exposure to fat-soluble toxins and heavy metals.metals.

Oxidative stress.Oxidative stress.

Excessive hydrogenation of fats in the Excessive hydrogenation of fats in the stomach altering the pepsin/HCl balance.stomach altering the pepsin/HCl balance.

Hypothyroid condition.Hypothyroid condition.

High CholesterolHigh Cholesterol

Lubricator proteins are not being broken Lubricator proteins are not being broken down properly or combustion is not down properly or combustion is not available at the following levels:available at the following levels:

Proper digestion and the preparation of proteins to be Proper digestion and the preparation of proteins to be assimilated into the bloodstream.assimilated into the bloodstream.

• Preparation and formation of cholesterol in the liver.Preparation and formation of cholesterol in the liver.

• Cellular level for hormone production/penetration/ Cellular level for hormone production/penetration/ impact on body metabolism.impact on body metabolism.

• Hypofunctioning ant. pituitary/hypothalamus gland.Hypofunctioning ant. pituitary/hypothalamus gland.

Bile emulsification condition.Bile emulsification condition.

Low CholesterolLow Cholesterol Oxidative Stress.Oxidative Stress.

Heavy Metal Poisoning.Heavy Metal Poisoning.

Free Radical Damage.Free Radical Damage.

Cancer.Cancer.

Fat is congested in the liver and is not able to be Fat is congested in the liver and is not able to be metabolized due to congestion and swelling in the metabolized due to congestion and swelling in the sinusoids.sinusoids.

The iodine is failing to release the nitrogen bond.The iodine is failing to release the nitrogen bond.

Imbalance of the Pepsin/HCl ratio.Imbalance of the Pepsin/HCl ratio.

Congestion in the digestive tract due to bile salt Congestion in the digestive tract due to bile salt inadequacy.inadequacy.

Hyper-functioning pituitary or hypothalamus.Hyper-functioning pituitary or hypothalamus.

High HDLHigh HDL Low HDLLow HDL

Exposure to Exposure to pesticides (>90).pesticides (>90).

Increased Toxicity Risk.Increased Toxicity Risk. Constipation.Constipation. Not enough exercise.Not enough exercise. High sugar/high High sugar/high

carb/low fat intake.carb/low fat intake.

CHOLESTEROL PROTOCOLSCHOLESTEROL PROTOCOLSGeneral SupportGeneral Support:: Cholaplex – 3 capsules 3 times daily with meals.Cholaplex – 3 capsules 3 times daily with meals. Soy Bean Lecithin – 2 perles 3 times daily with Soy Bean Lecithin – 2 perles 3 times daily with

meals.meals. Linum B6 – 5 perles 3 times daily with meals.Linum B6 – 5 perles 3 times daily with meals. Cyruta – 2 tablets 3 times daily with meals.Cyruta – 2 tablets 3 times daily with meals. Garlic – 1 capsule 3 times daily with meals.Garlic – 1 capsule 3 times daily with meals. Vitanox - 1 tablet 3 times daily with meals.Vitanox - 1 tablet 3 times daily with meals.

Liver/Gall Bladder SupportLiver/Gall Bladder Support:: Livaplex – 2 capsules 3 times daily with meals.Livaplex – 2 capsules 3 times daily with meals. AF Betafood – 2 tablets 3 times daily with meals.AF Betafood – 2 tablets 3 times daily with meals.

Thyroid SupportThyroid Support:: Thytrophin – 1 tablet 3 times daily with meals.Thytrophin – 1 tablet 3 times daily with meals. Allorganic Trace Minerals - 1 tablet 3 times daily Allorganic Trace Minerals - 1 tablet 3 times daily

with meals.with meals. Bladderwrack - 5mL 3 times daily.Bladderwrack - 5mL 3 times daily.