Draft of 20.04.2015

The fifth EBMT training course for paediatricians and

paediatric nurses on HSCT in children and adolescents

Morocco, Marrakech 14-17 May 2015

Developing hematopoietic stem cell transplantation in Africa

With the support of

Venue: Hotel Atlas Asni – Marrakech, Avenue Mohammed VI Marrakech, 40000, Morocco

web site www.smhop.org.ma

Organization

Directors Mhamed Harif, Giorgio Dini, Francesco Frassoni and Peter Bader

Local organizing agency

Sigma-Co; director Dr Azeddine Tanji ; e-mail is sigmacotravel@gmail.com, Local Organizers

Asmaa Quessar (quessar.a@gmail.com) Abdellah Madani (madani.hemato@gmail.com) Laila Hessissen (lailahsn@gmail.com) Mohammed Khattab (khattabmoh@yahoo.fr) Lahoucine Mahmal (mahmall@yahoo.fr) Jamila El Houdzi (ejamila11@yahoo.fr) Ilias Tazi (tazi_illias@hotmail.com)

Local Nurses Organizers:

Siham Moutassaddiq (moutassaddiqs@gmail.com) Scientific Secretariat Roberta Cancedda, Carivaldo Vasconcelos Local organizing Secretariat

Jamila El Houdzi ebmt2015marrakech@gmail.com Course Structure: Lectures on basic and “hot” topics given by experts for HSCT in children and adolescents are followed by case discussions. Welcome in Marrakech

Welcome in Marrakech, the red city, the capital of the south of Morocco. A mixture of Berber,

Arab and African culture, definitely modern but without losing its identity. Marrakech, a mythical

city, cultural capital, inspiring artists, modes and events. Marrakech is also a good place to meet,

to share knowledge and build friendship. The organizers are preparing a good scientific program

and hoping to make it also an inspiring opportunity for development of paediatric Hematopoietic

Stem Cell transplantation in the continent.

Aim of the Course

This course is unique opportunity for young physicians and nurses to get the latest developments in hematopoietic stem cell transplantation (HSCT) in children and adolescents and also an opportunity of addressing adapted approaches in developing countries. Very few centers of HSCT are in place in Africa and Arab countries. Keeping with the mission of European Group for Blood and Marrow Transplantation (EBMT) to promote and facilitate access to state-of-the-art and 7877cutting-edge knowledge in blood and marrow transplantation the course will explore the major issues impacting on HSCT in children and adolescents. Targeted audience

Many leading paediatric haematologists/oncologists are included among the speakers; the course is addressed specifically to postgraduate/resident level young physicians and paediatric nurses. Participation will be limited to 100. Submitted abstracts will be scored and best abstracts will be prized. Participants presenting selected abstracts will be awarded with grants covering registration and housing. Course Structure

Lectures on basic and “hot” topics given by experts for HSCT in children and adolescents are followed by case discussions. Social activity: City tour

FACULTY

MEMBER COUNTRY MEMBER COUNTRY

Abdellati Sniba Morocco Hbabou Halima Morocco

Admou Brahim Morocco Hadir Salsabil

Morocco

Anbari R. Morocco Harif Mhamed Morocco

Ayad Ahmed Jordany Hawaj Ghufran Saudia Arabia

Ayas Mouhab

Saudia Arabia Hshmati Farhad France

Babic Aleksandra Italy Hessissen Laila Morocco

Bader Peter Germany Hutt Daphna Israel

Balduzzi Adriana Italy Hvidt Lise Denmark

Bekkali Rachid Morocco Khattab Mohamed Morocco

Belkheim Reggie Saudia Arabia Lanino Edoardo Italy

Benchekroun Said Morocco Lawitschka Anita Austria

Benihya Mohamed Morocco Mank Arno The nederland

Dalle Jean-Hughes France Meskini Malika Morocco

Deiana Marco Italy Moutassaddiq Siham Morocco

Dini Giorgio Italy Peters Christina Austria

Duhaim Aolah Saudia Arabia Quessar Asmaa Morocco

El Faiz Meryem Morocco Reddahi Mohamed Morocco

Elhoudzi Jamila Morocco Stenvall Merja Finland

Elmadani Abdellah Morocco Tazi Ilias Morocco

Faulkner Lawrence Italy Trigoso Eugenia Spain

Forni G. Luca Italy Vernant Paul France

Frassoni Francesco Italy Viprakasit Vip Thailand

Garmouh Brahim Morocco Willasch Andre Germany

Gardino Paolo Italy

Scientific program

THURSDAY 14 MAY 2015

14.00-18.00: Registration

Sa: 16.00-17.00 Symposium of Macopharma Extracorporeal Photochemotherapy Farhad Hshmati Sb: 17.00-18.00 Symposium of TerumoBCT

18.00-20.00 : Opening Session 18.00 Marrakech, the red city between an African town and Europe tbd 18.10 The PDs WP and the pediatric nurses committee P. Bader, E.Trigoso 18.20 EBMT NG introduction and overview A. Babic 18.30 The history of HSCT in Morocco S.Benchekroun 18.45 The PDWP and Training Courses for pediatricians and pediatric nurses on HSCT in Children and adolescents G.Dini 19.00 The Rotary, Gaslini and Morocco alliance. P. Gardino 19.10 Activity of Lalla Salma Foundation R. Bekkali 19.20 History of HSCT Transplantation and future developments F. Frassoni 19.50 Stem cell transplantation in developing countries. Challenges and special needs M. Harif

20.15 Cocktail reception

FRIDAY 15 MAY 2015

07.30-08.30: Breakfast meet-the expert sessions

Specific characteristics of a pediatric transplant unit C. Peters

Organisation of a Transplant Unit P. Bader

The central role of international nursing cooperation A. Babic

Organization of a Transplant Unit in developing countries L. Faulkner

S2: 08.30-10.00 HLA typing and donor selection (Pediatricians) Discussants: A. Balduzzi, B.Admou HLA typing and the challenge of building “An African Registry ?” B. Admou How to select a donor and a stem cell source A. Balduzzi S3: 08.30-10.00 Nursing aspects of care (Pediatric nurses) Discussants: S. Moutassaddiq, M. Deiana

Chemotherapy safe preparation and administration M. Stenvall Nurses and chemotherapy M.Reddahi

Isolation rules B. Garmouh & S.Abdellati

10.00-10.30: Coffee break

10.30 - 12.00 Round table and case discussion how to choose a donor and stem cell source

Discussants: A. Balduzzi, E. Lanino

Examples of difficult unrelated donor searches

10.30 - 12.00 Nurses workshop Discussants: A. Mank , R. Belkheim , E. Trigoso

0 - 12.00 Round table How could we prepare a protocol? Evidence based nursing. Research in nursing care.c

12-12.30 Case presentation and discussion Discussants: tbd

S4: 12.30-13.00: Conditioning regimens (Pediatricians) Discussants: M.Harif Conditioning regimens L. Faulkner S5: 12.00-13.00: Patient education (Pediatric nurses) Discussants: A Mohamed, M.Meskini

Patient and family education: from theory to practice M. Deiana Patient and family education: between barriers and strategy A. Mohamed

13.00-14.00: Lunch S6: 14.00-16.00: Cancer and red cell disorders (Pediatricians) Discussants: M. Ayas, A. Ayad

Models for improving access to BMT in emerging countries L. Faulkner Cancer Epidemiology in Morocco and Africa: J.ELhoudzi Thalassemia/Sickle cell disease M. Ayas HSCT in childhood solid tumors A. Ayad

S7 : 14.00-16.00: Nursing aspects of care II: (Pediatric nurses) Discussants: M. Stenvall, H. Hbabou

GvHD G. Hawaj Pain management A. Duhaim

Early complications: fever and neutropenia E. Trigoso

The critical patient L. Hvidt

16.00-16.30: Coffee break S8 : 16.30-17.30: GvHD. Prevention-treatment (Pediatricians and Pediatric nurses) Discussants: A.Quessar- JP Vernant

Acute GVHD P. Vernant Chronic GvHD A.Lawitschka

S9 : 16.30-17.30: Early complication (Pediatric nurses) Discussants: D. Hutt, M.Reddahi

Endocrine late effect in survivers of paediatric SCT D. Hutt Donors aspect R. Belkhein

17.30 City tour

20.00 Dinner - Meet the Expert

Table 1 : Early Complications of HSCT A.Lawitschka

Table 2 : Alternative HSCT P Bader, E. Lanino

Table 3 : Nurse issues M. Deiana, S. Moutassaddiq

Table 4: Nurse issues E. Trigoso, M.Reddahi

Table 5 : Acute leukaemia C Peters, F. Frassoni, A. Quessar

Table 6 : GvHD A. Balduzzi, P. Vernant

Table 7: Late Complications of HSCT, QOL G. Dini

Table 8 : Non malignant diseases J. H. Dalle, M. Ayas

Table 9 : Supportive care A. Madani , I.Tazi , G.L.Forni

Table 10 : Transplant in developing Countries M. Harif, P. Gardino, L. Faulkner

SATURDAY 16 MAY 2015 07.30-08.30: Breakfast meet-the expert sessions

The narrative medicine G. Dini

Pain control following HSCT , and palliative Care L. Hessissen

Cell therapy F. Frassoni

Aplastic anemia J.H.Dalle

S10 8.30-10.30: Supportive Care (Pediatricians and Pediatric nurses) Discussant: M.Khattab, JH Dalle

How to communicate J.H. Dalle Transfusion: good practice I. Tazi Chelation therapy for iron overload G.L Forni

The role of deferasirox on the management of IOL Vip Viprakasit

S11 : 08.30-10.30 Vascular access (Pediatric nurses) Discussants: G. Hawaj , R. Anbari

CVC E. Trigoso Venous acces for apheresis and photoapheresis. A. Babic Enteral nutrition/TPN S.Hadir

Cell infusion (cryopreserved vs fresh) G. Hawaj

10.30-11.00: Case presentation and discussion

Discussant: M. Harif, G.Dini 11.00-11.30: Coffee break and poster session S12: 11.30-12.30: Alternative donors (Pediatricians)

Discussants: C. Peters, M.Khattab

Cord Blood transplantation M. Ayas Haplo-Transplantation using T-cell depletion P. Bader

12.30-13.00: Case presentation and discussion Discussants:, M.Khattab

S13: 11.30-13.00: Nursing (Pediatric nurses) Discussants L. Hvidt ,Local Nurse

The role of the nurse coordinator in the approach of the donor S.Moutassaddiq & M. El Faiz EMBMT activities. R. Belkheim EBMT . Activities and opportunity for nurses. A. Babic

13.00-14.00: Lunch S14 : 14.00-15.00 late effects (Pediatricians and Pediatric nurses) Discussants: A. Lawitschka, S. Bencharkroune

Post SCT follow up and Passaport G. Dini Be strong and brave. I did it, now it is your turn! M. Benihya

15.00-17.00: Case presentation and discussion Discussants: A.Elmadani, C. Peters Negativity of Minimal residual disease in bone marrow after immunosuppression withdrawal in a child

with T-ALL submitted to Unrelated Cord Blood transplantation Mafra, Abb; Gomes, Brazil

S15 : 15.00-17.00 Open discussion (Pediatric nurses) Discussants: A. Lawitschka, tbd Mucositis M.Deiana Transfer of patients from the BMT unit to the ICU D.Hutt and E.Trigoso.

17.00-17.30: Coffee break S16 : 17.30-19.30: Leukemia (Pediatricians) Discussants: P. Bader, F. Frassoni

Strategies of the donor search for children with CR2 ALL lacking a MSD E. Lanino Indications for Hematopoietic Transplantation in Leukemia A. Balduzzi Conditioning for children with ALL: TBI or Chemotherapy? C. Peters Monitoring of Chimerism and MRD after SCT A. Willasch

20.00 Dinner

General information

Grants Grants covering registration fees and maybe local accommodations will be awarded on a competitive basis. Depending on demand and financial availability, the organizers foresee awarding 30 grants.

Candidates must meet eligibility and age/qualification criteria (e.g., < 36 years of age) and must present an abstract of no more than 400 words on either a particularly interesting clinical case or ongoing research activity in subject matter covered by the course syllabus. A Selection Panel will evaluate submitted abstracts, with awards being made according to scientific excellence and pertinence;

In addition, some abstracts will be selected for oral presentation.

To apply, candidates should send their abstract to the course Organizing Secretariat together with - a completed and signed registration form - curriculum vitae - a letter of motivation clearly stating the interests and reasons for applying to the course (one page maximum); - A letter of reference, preferably from the applicant’s current employer or director.

Candidates should note that the organizers regret that in no case can travel expenses be covered or refunded

Key dates

April 30th, 2015 : Deadline for early registration April 30th, 2015 : Deadline for abstract submission May 1, 2015 : Publication of final Course program

Registration fees

Until April 30, 2015 From May 1, 2015

Physicians 350 EUR 400 EUR

Nurses 150 EUR 150 EUR

Medical students 200 EUR 350 EUR

Accompanying person 100 EUR 150 EUR

Registration includes - Course tuition; - Course materials and proceedings (hard copy handouts of presentations and CD); - Meals, refreshments, social events: (6 Coffee breaks, 2 Working lunches, 2 Breakfast Meet the Expert Sessions, 1 Dinner Meet the Expert, 1 Cocktail reception/Buffet dinner, 1 Dinner)

REGISTRATION FORM

Please fill in this form in all its part and send it by fax or by e-mail with the appropriate payment

to the Organising Secretariat :

Sigmaco Business Travel Agency

Tel. : +212 522 20 90 96/92

Fax : +212 522 20 90 78

sigmacotravel@gmail.com

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PAYMENT

- By bank transfer (Transfer Fees not included)

Bank : ATTIJARIWAFA BANK Beneficiary : Sigamco

Business Travel Agency : Casa Tontonville

Adress : Angle Bd Abdelmoumen et Rue Med El Hayani

RIB Number: 007 780 0003647000462500 52

IBAN (swift code) : BCM AM AMC

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THE FIFTH EBMT TRAINING COURSE FOR PAEDIATRICIANS

AND PAEDIATRIC NURSES ON HSCT IN CHILDREN AND

ADOLESCENTS

Marrakech 14-17 May

2015

Venue : Hotel Atlas Asni – Marrakech, Avenue Mohammed VI Marrakech, 40000, Morocco

REGISTRATION ACCOMODATION

Name ............................................... First name ................................. Title ..............................................

Indicative prices for one night with breakfast, taxes

included Single Room Twin Room

Dirhams Dirhams

Atlas Asni 4* 79 € 98 €

Atlas Medina 5* 100 € 135 €

Taxes 30 Dhs/personne 30 Dhs/personne

- Arrival : ...... / ...... / ....... Departure : ...... / ...... / .......

number of nights : ......... ........ Type : Single Twin

- No booking will be confirmed without full prepayment of stay

Total Amount

PAYMENT

- By bank transfer (Transfer Fees not included)

Bank : ATTIJARIWAFA BANK

Beneficiary : Sigamco Business Travel

Agency : Casa Tontonville

Adress : Angle Bd Abdelmoumen et Rue Med El Hayani

RIB Number: 007 780 0003647000462500 52

IBAN (swift code) : BCM AM AMC

- By Credit Card (Visa .................. Mastercard ................ ). (Transfer Fees not included) Credit

card payment accepted until

Credit Card n. ..................................................... Expiration date . ............................................................ Code with 3 number

on the second side of your credit card ..................................................... Credit Card

Owner ............................................................................................................................................. Amount of ............................................................

Thank you for sending the copy of the transfer and Registration fees and

accomodation to : Fax : +(212) 5 22 20 90 78

Main sponsors