The Effect of BMP on the Expression of Cytoskeletal Proteins and Its Potential Relevance by Ruth L....

The Effect of BMP on the Expression of Cytoskeletal Proteins and Its Potential Relevance

by Ruth L. Vinall, and A. Hari Reddi

J Bone Joint Surg AmVolume 83(1 suppl 1):S63-S69

March 1, 2001

©2001 by The Journal of Bone and Joint Surgery, Inc.

Chondrocytes are exposed to a number of physical and biochemical external stimuli that can affect their phenotype, such as matrix components, mechanical forces, and growth factors and

cytokines.

Ruth L. Vinall, and A. Hari Reddi J Bone Joint Surg Am 2001;83:S63-S69


Chondrocytes grown in monolayer culture (left vertical panel) and suspension culture (right vertical panel) displayed different patterns of labeling for tensin, talin, paxillin, and focal

adhesion kinase (FAK).



Chondrocytes grown in suspension culture (confocal section series from the upper (A) to the lower (I) surface of the chondrocytes, scale μ5 m).



Chondrocytes grown in monolayer culture (confocal section series from the upper (A) to the lower (D) surface of the chondrocyte, scale bar = 5 μm).



The Effect of BMP on the Expression of Cytoskeletal Proteins and Its Potential Relevance by Ruth L....

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