THE CELL CYCLE AND CANCER. Control of the Cell cycle Control of the cell cycle.
The Cell Cycle Mitosis. The Cell Cycle The regular sequence of growth and division that cells...
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Transcript of The Cell Cycle Mitosis. The Cell Cycle The regular sequence of growth and division that cells...
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The Cell Cycle
Mitosis
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The Cell Cycle
The regular sequence of growth and division that cells undergo.
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The Cell Cycle
6 Parts Interphase Prophase* Metaphase Anaphase Telophase Cytokinesis
• *When mitosis begins.
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Stage 1: Interphase
During interphase the cell grows, makes a copy of its DNA, and prepares to divide into 2 cells. Cell grows - The cell grows to full size and
produces structures it needs. Copies DNA -Cell makes a full copy of the
DNA. This process is known as replication.• DNA is found in the chromatin.
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Stage 1: Interphase
Preparing for Division - After replication has occurred, the cell copies its centrioles.
• Centrioles - Cylindrical structures that produce microtubules used in mitosis.
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Stage 2: Mitosis
Mitosis - The stage during which the cell’s nucleus divides into two new nuclei.
During mitosis, one copy of the DNA is distributed into each of the two daughter cells. Daughter cells - The cells that are produced following
cell division.
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Stage 2: Mitosis Part 1
Prophase - Chromatin condenses in the nucleus to form chromosomes.
• Chromosomes are made of chromatin. The two chromatids that make up a chromosome is held together in the center by a centromere. (make a diagram.)
The centrioles move to opposite sides of the nucleus. The nuclear envelope breaks down.
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Stage 2: Mitosis
Part2
Metaphase -• Chromosomes line up across the center of the
cell.• Each chromosome attaches to a spindle fiber at
its centromere.• The spindle fibers are connected to the centrioles.
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Stage 2: Mitosis Part 3
Anaphase - • The centromeres split, and the chromatids
separate.• Each chromatid becomes a new chromosome.• New chromosomes move to opposite ends of the
cell.• Cell begins to stretch out as the opposite ends are
pushed apart.
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Stage 2: Mitosis
Part 4 Telophase -
• Chromosomes lose their rod-like appearance• New nuclear envelope forms around the bundle of
chromosomes.• Two halves separate even farther.
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Stage 3: Cytokinesis
Cytokinesis is the division of cytoplasm and organelles into each of the 2 new cells.
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Stage 3: Cytokinesis
During cytokinesis: Cell membrane pinches in around the middle of the
cell. Cell splits in two and divides the cytoplasm. Each daughter cell has an identical set of
chromosomes and about 1/2 the organelles. Cytokinesis leads back into interphase.
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Stage 3: Cytokinesis
Cytokinesis in PLANTS is different. A cell plate forms across the middle of the
cell, which gradually develops into the new cell membranes.
The new cell walls form around the cell membranes.
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DNA Structure
Double helix - Twisted ladder shape The sides of the ladder are made up of sugar
molecules called deoxyribose, and alternate with a phosphate molecule.
The rungs are made up of a pair of nitrogen bases. 4 nitrogen bases: adenine (A), thymine (T), guanine
(G), and cytosine (C).
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DNA Replication Process
The DNA “ladder” unwinds and unzips, leaving 1 of the 2 nitrogen bases on either side of the “ladder”.
Bases that are floating in the nucleus pair up with its appropriate partner. Adenine pairs with Thymine Guanine pairs with Cytosine