th Seminar on Exercise in Medicine
Transcript of th Seminar on Exercise in Medicine
The 6th Seminar on Exercise in Medicine
Trondheim 17-18th December 2015
ntnu.edu/cerg @CERG_ntnu cerg_ntnu CERG_NTNU facebook.com/CERG
The 6th
Seminar on Exercise in Medicine, Trondheim, 17-18th
December 2015
Dear Colleagues and Friends:
It is a pleasure to invite you to “The 6th
Seminar on Exercise in Medicine” in Trondheim the 17-18th
of December
2015. The seminar is hosted by the K.G. Jebsen Center of Exercise in Medicine/Cardiac Exercise Research Group
(ntnu.edu/cerg) at the Department of Circulation and Medical Imaging, at Norwegian University of Science and
Technology (NTNU), Trondheim, Norway.
This seminar brings together young and experienced researchers in the field of epidemiology, clinical cardiology,
exercise in medicine and basic mechanism of cardiovascular function. The main purpose is to discuss recent
progress in using exercise as medicine.
In contrast to the large international conferences, an intension by organizing this small seminar is to create an
informal and intimate setting, which we know set the stage for open discussions and brainstorming to create
new ideas for good research.
Thursday will be a very busy day from early morning to late night. The final program closes at 1630. You will have
some time to relax before departure for an outdoor dinner in the forest of Trondheim. Although this seem to be
stressful we promise that we will be taken good care of in a relaxing environment as soon as you have put on
your warmest clothes. We are hoping for nice cold weather with plenty of snow.
Friday we start up with program from the morning of and end the scientific session at 1515. For those of you that
are interested you will be invited to join a seminar called “Man in extreme environment” at 1900 on Friday night,
where you can relax and listen to some of the most experienced “nature explorers” in the world.
As organizers for this seminar we provide “the playing ground”, but it’s the players that make the game fun. We
are therefore deeply grateful if you would like to participate and share your time with us these days. We
welcome you to participate in this multidisciplinary setting.
Pictures from earlier seminars on Exercise in Medicine in Trondheim
Program 17th December 2015 Seminar on Exercise in Medicine, Trondheim
KA 11 – Knowledge Center, St. Olavs University Hospital
0830-0845 WELCOME AND REGISTRATION
Ulrik Wisløff
0845-0900
THE CARDIAC EXERCISE RESEARCH GROUP: PAST-PRESENT-FUTURE
PHYSICAL ACTIVITY AND CARDIOVASCULAR DISEASE: PAST – PRESENT - FUTURE Chair: Professor Martin Halle, Techniche Universität München, Germany.
Carl “Chip” Lavie
0900-0930
John Ochsner Heart and Vascular Institute, Ochsner Clinical School, New Orleans, USA
Physical activity and cardiovascular disease: Past and Present
Steven Blair
0930-1000
Prevention Research Center Public Health Research, University of South Carolina, USA
Physical activity and cardiovascular disease: The future
Ben Levine
1000-1030
Institute for Exercise and Environmental Medicine, Dallas, Texas, USA
Impact of lifelong exercise "dose" on left ventricular compliance and distensibility
1030-1100 COFFEE & FRUIT
EXERCISE TRAINING IN HEART FAILURE
Chair: Professor Volker Adams, University of Leipzig, Germany
Øyvind Ellingsen
1100-1130
K.G. Jebsen Center of Exercise in Medicine, NTNU
Moderate versus high intensity exercise training in heart failure with reduced ejection fraction
Mark Haykowsky
1130-1200
University of Texas at Arlington, Texas, USA
Heart failure with preserved ejection fraction—what do we know and what do we need to know?
Anthony Rosenzweig
1200-1230
Harvard Medical School and Massachusetts General Hospital, Boston, USA
Molecular mediators of exercise: Can we deliver the benefits effects of exercise in a pill?
1230-1330 LUNCH
BRAIN HEALTH
Chair: Linda Ernstsen, K.G. Jebsen Center of Exercise in Medicine, NTNU
Lene J. Rasmussen
1330-1400
Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen
Denmark
Role of mitochondrial dysfunction and genomic instability in Alzheimer`s disease: a search for
therapeutic strategies
Linda H. Bergersen
1400-1430
Brain and Muscle Energy Group and Healthy Brain Aging Centre at University of Oslo.
Lactate transport and signaling in the brain: potential therapeutic targets via exercise training?
Jorge Ruas
1430-1500
Molecular and Cellular Exercise Physiology, Karolinska Institutet, Sweden.
Therapeutic avenues for treating depression by targeting skeletal muscle
1500-1530 REFRESHMENT AND SNACKS (1903 BUILDING)
1530-1630
POSTER-UPDATE FROM K.G. JEBSEN CENTER OF EXERCISE IN MEDICINE Chair: Øivind Rognmo, K.G. Jebsen Center of Exercise in Medicine, NTNU
1830-2300 OUTDOOR DINNER FOR SPEAKERS AND INVITED – BUS PICK UP AT 1830
Program 18th
December 2015
Seminar on Exercise in Medicine, Trondheim
ENERGY METABOLISM IN HEALTH AND DISEASE Chair: Professor Bård Kulseng, St. Olavs University Hospital, Trondheim, Norway.
Juleen Zierath
0900-0930
Department of Molecular Medicine and Surgery, Karolinska Institutet, Sweden.
Exercise training as treatment of diabetes: Past – Present – Future
Johan Auwerx
0930-1000
The Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale in Lausanne,
Switzerland
Molecular physiology and systems genetics to understand metabolism in health, aging and disease
1000-1030 COFFEE & FRUIT
ACTIVE & SUCCESSFUL AGING
Chair: Professor Jorun Helbostad, Department of Neuroscience, NTNU
Dorthe Stensvold
1030-1100
K.G. Jebsen Center of Exercise in Medicine, NTNU
A randomized controlled study of the long-term effects of exercise training on mortality in elderly
people: The Generation 100 study
Maria A.F. Singh
1100-1130
University of Sydney, Sydney, Australia
Novel applications of progressive resistance training in older adults
Bjarne M. Nes
1130-1200
K.G. Jebsen Center of Exercise in Medicine, NTNU
HUNT 4 Fitness
1200-1300 LUNCH
TELEMEDICINE
Chair: Christian Gutvik, Technology Transfer Office, NTNU
Pinar Øztruk
1300-1330
Department of Computer and Information Science, NTNU
Telemedicine in chronic disease management: Past – Present – Future
Lasse Berre
1330-1400
Berre, Trondheim, Norway
Innovation: Listen to your heart
1400-1430 COFFEE & FRUIT
CARDIOVASCULAR IMAGING Chair: Professor Toril N. Hernes, Department of Circulation and Medical Imaging, NTNU
Lasse Løvstakken
1430-1500
Centre for Innovative Ultrasound Solutions at Department of Circulation and Medical Imaging, NTNU
Ultrasound imaging and quantification of cardiovascular disease: present and future directions
1500-1515 CONCLUDING REMARKS
1900-2200
MAN IN EXTREME ENVIRONMENT Chair: Svein Erik Gaustad
Emil Eide Eriksen
Rowing the Atlantic
Justin Jones Tasman expedition: Crossing the Ditch - Daring to dream then riding out the storm
James Castrission
Antarctic expedition: Extreme South - A journey to hell and back
The speakers
Steven Blair
Professor in the Departments of Exercise Science and Epidemiology and
Biostatistics at the Arnold School of Public Health, University of South
Carolina. His research focuses on the associations between lifestyle and
health, with a specific emphasis on exercise, physical fitness, body
composition, and chronic disease.
Lene Juel Rasmussen
Professor at the University of Copenhagen and Managing Director of the
interdisciplinary aging center, Center for Healthy Aging, residing within the
faculty of Health and Medical Sciences. Her research aims to unravel the
complex molecular basics of aging and the development of aging
associated diseases.
Maria Fiatarone Singh
Professor and a geriatrician, board certified in both Internal Medicine and
Geriatric Medicine in the USA and Australia, who has held the inaugural
John Sutton Chair of Exercise and Sport Science in the Faculty of Health
Sciences, and Professorship, Sydney Medical School, at the University of
Sydney since 1999. Her research, clinical, and teaching career has focused
on the integration of medicine, exercise physiology, and nutrition as a
means to improve health status and quality of life in older adults.
Jorge Ruas
Assistant Professor at the Department of Physiology and Pharmacology,
Karolinska Institutet, and group leader for the Molecular and Cellular
Exercise Physiology research group. He received his Pharm.D. degree from
the University of Lisbon, his Ph.D. from Karolinska Institutet, and returned
to Sweden after pursuing postdoctoral studies at Harvard Medical School.
Benjamin D. Levine
Founder and Director of the Institute for Exercise and Environmental
Medicine at Texas Health Presbyterian Hospital Dallas where he also holds
the S. Finley Ewing Chair for Wellness and the Harry S. Moss Heart Chair
for Cardiovascular Research. He is Professor of Internal
Medicine/Cardiology and Distinguished Professor of Exercise Sciences at
the University of Texas Southwestern Medical Center. His global research
interests center on the adaptive capacity of the circulation in response to
exercise training, decondition, aging, and environmental stimuli such as
spaceflight and high altitude.
Juleen R. Zierath
Professor of Clinical Integrative Physiology and head of the Section of
Integrative Physiology at the Dept. of Molecular Medicine and Surgery and
the Dept. of Physiology and Pharmacology at Karolinska Institutet. She is
also appointed Professor of Integrative Physiology at University of
Copenhagen, where she is a Scientific Director at the Novo Nordisk
Foundation Center for Metabolic Research. Her research has provided
evidence for the physiological regulation of insulin signaling pathways in
skeletal muscle, revealing key steps are impaired in diabetic patients.
Mark Haykowsky
Professor and Moritz Chair in Geriatrics in the College of Nursing and
Health Innovation at The University of Texas at Arlington. His Research
program examines (1) the biologic mechanisms responsible for the decline
in health related fitness across the heart failure continuum, and the role of
exercise training to improve cardiovascular and skeletal muscle function;
(2) the efficacy of exercise training to reverse chemotherapy mediated
cardio-toxicity in women with breast cancer, and; (3) cardiac mechanics
and left ventricular remodeling in athletes.
Anthony Rosenzweig
Chief of cardiology and co-director of the Corrigan Minehan Heart Center.
He specializes in general noninvasive cardiology, with a particular interest
in cardiovascular genetics and cardiovascular disease prevention. Dr.
Rosenzweig's research is focused on heart failure and understanding the
clinical implications of fundamental biological processes regulating cell
growth, death and regeneration in the heart.
Linda Hildegard Bergersen
Professor in Neurobiology and work as a group leader at the Department
of Anatomy University of Oslo, Brain and Muscle energy group which is
part of Nansen Neuroscience Network. She is also a guest Professor at the
Center for Healthy Aging at the Panum Institute in Copenhagen. The main
goal in her group is to understand enegy failure in the brain and how we
both can rescue and cure enegy failure in the brain.
Johan Auwerx
Professor at the École Polytechnique Fédérale in Lausanne, Switzerland,
where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has
been using molecular physiology and systems genetics to understand
metabolism in health, aging and disease. Much of his work is focused on
understanding how diet, exercise and hormones control metabolism
through changing the expression of genes by altering the activity of
transcription factors and their associated cofactors.
Carl “Chip” Lavie
Dr. Lavie is Professor of Medicine and Medical Director, Cardiac
Rehabilitation and Preventive Cardiology; Director, Exercise Testing
Laboratory; and Staff Cardiologist, Echocardiographic Laboratory at the
John Ochsner Heart and Vascular Institute in New Orleans, Ochsner
Clinical School-The University of Queensland School of Medicine and he
previously served for 10 years as Associate Director of the Internal
Medicine Training program.
Øyvind Ellingsen
Øyvind Ellingsen is a Professor of Cellular Cardiology at the Norwegian
University of Science and Technology (NTNU) and a Consultant Physician
at the Department of Cardiology, St. Olavs Hospital, Trondheim, Norway.
Dr. Ellingsen founded the Laboratory of Cellular Cardiology at NTNU in
1996. The focus of the lab is Exercise in Medicine. Its long-term goals are
to understand the mechanisms of the beneficial effects of exercise in
cardiovascular disease, to translate them into better programs for
prevention and rehabilitation, and to identify new targets for medical
therapy.
Dorthe Stensvold
Dorthe Stensvold, Post Doctor at K.G. Jebsen Center of Exercise in
Medicine, NTNU, Trondheim, is project leader of Generation 100, a large
randomized clinical study that evaluates the effect of regular exercise
training on morbidity and mortality in elderly people.
Bjarne M. Nes
Post Doctor at K.G. Jebsen Center of Exercise in Medicine, NTNU,
Trondheim. His research focuses on exercise and cardiorespiratory fitness
in cardiovascular disease prevention by using population based studies
from the large HUNT-cohort.
Lasse Løvstakken
Lasse Løvstakken is Professor at the Dept. of Circulation and Medical
Imaging, NTNU, Trondheim. His research interests is targeted towards
medical ultrasound imaging, a method where echoes from high-frequency
sound waves emitted into the body can be used to make images and
measure properties of tissue and blood flow.
Pinar Øzturk
Pinar Øzturk is Associate Professor at Dept. of Computer and Information
Science at NTNU, Trondheim. Pinar’s main research area is artificial
intelligence but she does multidisciplinary research linking AI with other
parts of cognitive science. Her research activities lie in knowledge
representation and modellling, case-based reasoning, multiagent systems,
and recently text mining/information extraction areas.
Lasse Berre Lasse Started BERRE in 1996 after returning from more than 6 years in
California, where he studied photography and later worked as a
photographer within fashion and advertising. He has since worked with
photography, visual concepts, communication and brand building for both
well known national and international brands. Lasse is educated from
Brooks Institute of Photography, Santa Barbara, CA.