Team 19 Kaitlyn Clarke Brittany DePoi Andrew Reynolds Adarsha Selvachandran Client: Dr. Wei Sun.
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Transcript of Team 19 Kaitlyn Clarke Brittany DePoi Andrew Reynolds Adarsha Selvachandran Client: Dr. Wei Sun.
Fabrication of Percutaneous
Transvenous Mitral Annuloplasty Testing
Device
Team 19Kaitlyn ClarkeBrittany DePoi
Andrew ReynoldsAdarsha Selvachandran
Client: Dr. Wei Sun
Project Overview
Dr. Sun has requested a testing device that will allow his research team to obtain physical evidence regarding the response of cardiac tissue to implantation of the Percutaneous Mitral Annuloplasty System for the Treatment of Mitral Regurgitation ( aka. “stent bridge constriction device”)
Required project components:o Biological environment regulatoro Marker Tracking Systemo Force Determination Systemo Ultrasonic Detection
Distal Anchor
Nitinol Bridge
Proximal Anchor
Biological Environment Regulator
Purpose: support heart and simulate naturally occurring environmental conditions such as temperature, pressure, and blood flow
3 main components:o Water batho Camera mount and frameo Heart mount
Biological Environment Regulator Water Bath and Camera Mount
Water Batho Clear cast acrylic
sheetso Two separate baths
(inner and outer) Camera Mount
o Aluminumo Adjustable
Biological Environment Regulator Heart Mount
Secure enough to hold heart stable, loose enough to allow heart to move naturally in response to the stent bridge constriction device
Aluminum base Small hooks to securely hold
heart in place Rigid tube inserted into the
ascending aorta, down into the left ventricleo Structural supporto Pathway for saline that will
control pressure in the mitral valve
Base
Aorta Tube
Marker Tracking System
Purpose: Understand mechanical changes experienced by heart during stent deployment
15-20 small graphite markers on mitral annulus plane
2 cameras 30-45 degrees apart to capture image Calibration Cube in field of view of each camera
Marker Tracking SystemAlgorithm
Direct linear transformation (DLT) MATLAB codeo Recreate image with reference to the three-dimensional
planeo Determine the 3-D position of each marker o Keep track of each marker and it’s movements from
frame to frameo Recognize if a marker leaves the frame of view of one of
both cameraso Calculate stress, strain, and deformation
Force Determination System
Purpose: Determine relationship between force applied on the mitral annulus by stent and the decrease in mitral valve prolapse
FlexiForce Sensorso Force measured at specific point as opposed to continuouso Use 6 sensors in an attempt to get more thorough data
Ultrasonic Detection Purpose: Capture Image of the coronary sinus before and after
stent deployment Ultrasound Machine has 2 probes one probe port Probe attached to machine will be changed between deployment
of stents
Distal Stent
Proximal Stent
Aortic Root
Mitral Valve (open)
Coronary Sinus
Mitral Valve (closed)
Coronary Sinus
Distance between coronary sinus and
valve
What’s Next?(We’ve ordered and received Plexiglas/FlexiForce)
Begin to build water bath Obtain computer from Kewei and begin
downloading Vision Software Build FlexiForce circuit and experiment
with sensors to determine the best way to adhere/use them
Test ultrasound to become comfortable with use and to determine the best settings to use