Taylor D. Smith, B.S. 100 Lakeshore Dr, Apt 117

Lexington, KY 40502 Telephone: (859) 229-6994 / e-mail: taylor@taylorsmith.tech

EDUCATION University of Kentucky, Lexington, KY 2013 B.S. Chemistry (Biochemistry Option) Summa Cum Laude Departmental Honors University of Kentucky, Lexington, KY 2013 B.S. Mathematics Summa Cum Laude Departmental Honors Cumulative GPA: 3.93 GRE Verbal: 160 GRE Quantitative: 158 GRE Analytical: 4.5 PCAT Composite Score: 430 (94th percentile) Awards/Honors Merck Index Award ($250) 2013 Arts and Sciences, Department of Chemistry University of Kentucky Kash Senior Pre-Med Scholarship ($750) 2012 College of Arts and Sciences University of Kentucky Commonwealth Scholarship ($10,000) 2009 University of Kentucky POST BACCALAUREATE WORK Spinal Cord and Brain Injury Research Center Sept 2013 – Dec 2015 University of Kentucky, Lexington, KY Laboratory Technician Biochemistry and Magnetic Resonance Imaging MEMBERSHIPS AND SCIENTIFIC SOCIETIES American Chemical Society 2013 Phi Beta Kappa National Academic Honor Society 2013 Golden Key International Honour Society 2011

PUBLICATIONS Patel S.P., Sullivan P.G., Pandya J.D., Goldstein G.A., VanRooyen J.L., Yonutas H.M.,

Eldahan K.C., Morehouse J., Magnuson D.S., Rabchevsky A.G. N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma. 2014. Experimental Neurology 257: 95-105. Acknowledged.

Patel S.P., Smith T.S., VanRooyen J.L., Powell D., Cox D.H., Sullivan P.G., Rabchevsky A.G.

Serial Diffusion Tensor Imaging In Vivo Predicts Long-Term Functional Recovery and Histopathology in Rats Following Different Severities of Spinal Cord Injury. Dec 2015. Journal of Neurotrauma. Co-First Author.

Visavadiya N.P., Patel S.P., VanRooyen J.L., Sullivan P.G., Rabchevsky A.G. Cellular and

subcellular oxidative stress parameters following severe spinal cord injury. 2016. Redox Biology 8(2016): 59-67. Acknowledged.

Posters/Abstracts: Smith T.D., Patel S.P., Rabchevsky A.G. Analysis of Markers of Oxidative Damage in Rat

Spinal Cord Following Spinal Cord Injury. University of Kentucky Department of Chemistry Undergraduate Poster Competition, Lexington, KY. April 2013.

Patel S.P., VanRooyen J.L., Visavadiya N.P., Smith T.D., Sullivan P.G. and Rabchevsky A.G.

2014. Treatment with ketone bodies preserves mitochondrial function and reduces oxidative stress following contusion spinal cord injury. Society for Neuroscience Annual Meeting, Washington, DC. November 2014.

Rabchevsky A.G., Eldahan K.C., VanRooyen J.L., Wang C.Y., Smith T.D., Cox D.H., Patel

S.P. Gabapentin management of autonomic dysreflexia: effects on system inflammation. Society for Neuroscience Annual Meeting, Washington, DC. November 2014.

VanRooyen J.L., Patel S.P., Eldahan K.C., Smith T.D., Cox D.H., Rabchevsky A.G.

Mitochondrial Supplementation after Spinal Cord Injury Maintains Cellular Bioenergetics. Bluegrass Society for Neuroscience Day, Lexington, KY. March 2015.

VanRooyen J.L., Patel S.P., Eldahan K.C., Smith T.D., Cox D.H., Rabchevsky A.G.

Mitochondrial Transplantation to Restore Cellular Bioenergetics after Spinal Cord Injury. UK Healthcare Clinical Neuroscience Expo, Lexington, KY. March 2015

RESEARCH PROJECTS In-vivo quantitative assessment of spinal cord injury using diffusion tensor imaging PI: Alexander G. Rabchevsky | 2013 – 2015 • Magnetic resonance (MR) and diffusion tensor (DT) imaging sequence development and

optimization for in-vivo assessment of rat spinal cord

• Independent operation of MRI scanner including animal handling and image acquisition • Software development and scripting for assessment of acquired MR and DT images • Development and testing of specific metrics to quantify and prognosticate spinal cord

injury severity from MR and DT images Pharmacological interventions for neuroprotection following traumatic spinal cord injury PI: Alexander G. Rabchevsky | 2013 – 2015 • Biochemical assays including western blot and ELISA of markers of oxidative stress and

inflammation • Rodent behavioral assessments including locomotor and kinematic gait assessments • Tissue staining, microscopy, and histological analysis of injured spinal cord tissue

Gabapentin Management of Autonomic Dysreflexia PI: Alexander G. Rabchevsky | 2013 – 2015 • Development of algorithms to analyze recorded telemetric data (i.e. blood pressure and

heart rate) to detect and quantify numbers of spontaneous events of autonomic dysreflexia

• Development of algorithms and software to quantitatively assess hemodynamics and severity of recorded, induced events of autonomic dysreflexia

Contributions of the mTOR signaling pathway to the development and extent of autonomic dysreflexia PI: Alexander G. Rabchevsky | 2015 • Western blot analysis for members of mTOR pathway and markers of neuronal activity • Incorporation of novel electric field sensors into existing telemetric recording apparatus with

subsequent analysis and validation Skills Magnetic Resonance Imaging

• Sequence development/optimization • Image acquisition and data processing • Discreet quantitative and morphological assessments of MR images

Software development and application scripting • Operating system shell scripting (strength: linux) • Visual Basic for Applications (VBA) • Limited experience in signal processing • Developed full ‘software suite’ for MRI analysis of rat spinal cord including installer,

manual, and individual analysis modules Biochemistry

• Western Blot • ELISA • Fluorospectrometry

Surgical/Behavioral • Rodent anesthesia administration

• Pre/Post-surgical rodent care • BBB and BMS locomotor rating scales • Quantitative kinematic gait analysis

Administrative

• Laboratory supply ordering and inventory management • Reconciliation and accounts payable • Maintaining legal/ethical/environmental compliance in a scientific laboratory setting

References Alexander G. Rabchevsky, PhD Professor of Physiology Department of Physiology Spinal Cord and Brain Injury Research Center University of Kentucky College of Medicine B471 BBSRB, 741 S. Limestone St., Lexington KY 40536 Phone: (859) 323-0267 E-mail: agrab@uky.edu Patrick G. Sullivan Associate Professor Department of Anatomy and Neurobiology Spinal Cord and Brain Injury Research Center University of Kentucky College of Medicine B461 BBSRB, 741 S. Limestone St., Lexington KY 40536 Phone: (859) 323-4684 E-mail: patsullivan@uky.edu Samir Patel Research Assistant Professor Department of Physiology Spinal Cord and Brain Injury Research Center University of Kentucky College of Medicine B461 BBSRB, 741 S. Limestone St., Lexington KY 40536 Phone: (859) 323-6477 E-mail: skpate2@uky.edu