Table of Contents -...
Transcript of Table of Contents -...
Table of Contents
Preface ......................................... xvii
................................. AbouttheEditor .xix
1 . Hemolytic Transfusion Reactions .................... 1 Robertson D . Davenport. MD
Incidence ......................................... 2 Clinical Presentation ................................. 3 Complications ...................................... 6 Causes of Hemolytic Transfusion Reactions ................ 8 Differential Diagnosis ............................... 10 Pathophysiology ................................... 21 Treatment ........................................ 28
....................................... Prevention 32 Summary ........................................ 40 References ....................................... 40
2 . Febrile Nonhemolytic Transfusion Reactions .......... 53
Nancy M . Heddle. MSc. FCSMLS(D)), and Kathryn E . Webert. M D
Clinical Presentation ................................ 54 Differential Diagnosis ............................... 55 Frequency ....................................... 58 Mechanisms ...................................... 64 Prevention ....................................... 72 Treatment and Management .......................... 83 Further Research ................................... 90 References ....................................... 91
3 . Allergic and Anaphylactic Reactions ................. 99
Elefherios C . Vamvakm. A-D. PN)
Clinical Presentation and Complications ................ 101 Differential Diagnosis .............................. 103
Transfusion Reactions
....................................... Frequency 105 ..................................... Mechanism -108
Diagnosis ....................................... 121 ....................................... Treatment 124
Prevention ...................................... 125 Summary ....................................... 137
...................................... References 138
................. 4 . Acute Pain Transfusion Reactions 149
Robertson Davenport. MD
....................................... Incidence 149 ............................... Clinical Presentation 150
..................................... Mechanism -151 .............................. Differential Diagnosis 152
Prevention ...................................... 152 ...................................... References 152
......................... 5 . Bacterial Contamination 153
Sandra Ramlrez-Arcos MSc. PhD. and Mindy Goldman. MD. ERCP(C)
................................ Historical Overview 153 ....................... Presentation and Complications 154
.......................... Microorganisms Implicated 157 .............................. Differential Diagnosis 161
....................................... Frequency 161 ....................... Mechanisms of Contamination 163
............................ Diagnosis and Strategies 166 Treatment ....................................... 168
............................... Prevention Strategies 168 ...................................... Conclusion 180 ...................................... References 181
.............. 6 . Transfusion-Related Acute Lung Injury 191
Patricia M . Kopko. MD. and Mark A . Popovsky. MD ...................................... Definitions 192
................ Clinical Presentation and Complications 192 ....................................... Incidence 195
................................ Patient Risk Factors 196
Table of Contents
.............................. Differential Diagnosis 197 ........................ Implicated Blood Components 198
Mechanism ...................................... 199 Diagnosis ....................................... 205
....................................... Treatment 206 Prevention ...................................... 207
...................................... TheFuture 209 References ...................................... 209
......... 7 . Transfusion-Associated Graftaft-. Host Disease 217
Caron A . Jacobson. MD; Kenneth C . Anderson. MD; and Edwin P . Alyea. MD
................ Clinical Presentation and Complications 218 Diagnosis ....................................... 219 Pathogenesis .................................... 220
....................................... Incidence 223 .............................. Patient Groups at Risk 223
....................................... Treatment 227 ....................... Prevention: Gamma Irradiation 227
................................... NewDirections 229 References ...................................... 231
................ 8 . Hypotensive Transfusion Reactions 239
Heather A . Hume. MD. FRCPC, and Pierre Robillard. MD. FRCPC
............................... Clinical Presentation 240 .................... Incidence-Hemovigilance Reports 244
.................................. Pathophysiology 246 ......................... Management and Prevention 255
...................................... Conclusion 257 References ...................................... 257
......................... 9 . Posttransfusion Purpura 263
Janice G . McFarland. MD ............................ Platelet-Specific Antigens 263
....................................... Frequency 264 ............................... Clinical Presentation 264
Transfusion Reactions
.............................. Differential Diagnosis 271 ..................................... Mechanism -272
Diagnosis ....................................... 278 ....................................... Treatment 278
Prognosis ....................................... 280 ..................................... Special Cases 281
Summary ....................................... 281 ...................................... References 282
1 0 . Transfusion Reactions Associated with Hematopoietic ..................... Progenitor Cell Reinfusion 289
Laura Cooling. MD. MS. and Jed B . Gorlin. MD. MBA .................... General Overview of HPC Products 290
........................ Etiology of Infusion Reactions 291 .......................... Specific Infusion Toxicities 296
............. Strategies to Prevent or Ameliorate Reactions 309 ............................ Reporting Requirements 315
Summary ....................................... 316 ...................................... References 316
......... 1 1 . Transfusion-Associated Circulatory Overload 327
Mark A . Popovsky. MD
.................... Clinical Presentation and Diagnosis 327 ............................ Demographics of TACO 329
....................... Role of the Clinical Laboratory 329 .......................... Incidence and Risk Factors 330
............................ Morbidity and Mortality 332 Mechanism ..................................... 332
....................................... Flow Rate 333 .............................. Differential Diagnosis 333
.................................... Management 334 Prevention ...................................... 334 Summary ....................................... 335
...................................... References 335
xii
Table of Contents
1 2 . Adverse Consequences of Autologous Transfusion Practice ................................... 339
Zoe K . McQuilten. MD; Erica M . Wood. MD; and Roslyn A . Yomtovian. MD
Rationale for Autologous Transfusion Practice ............ 340 Clinical Governance of Autologous Transfusion ........... 344 Types of Autologous Transfusion ...................... 346 Patient Selection for Autologous Transfusion Procedures .... 359 Adverse Reactions in Donors for PAD .................. 360 Autologous Transfusion Reactions and Complications ...... 368 Conclusion ...................................... 391 References ...................................... 392
13 . Complications of Therapeutic Apheresis ............ 407
Ronald G . Strauss. MD. and Kendall P . Crookston. MD. PhD
Generaloverview ................................ 409 Citrate Reactions ................................. 412 Hypovolemia and Vasovagal Reactions .................. 422 Plasma Protein Depletion ........................... 424 Unusual and Controversial Complications ............... 428 Conclusions ..................................... 432 References ...................................... 433
14 . Complications of Massive Transfusion .............. 439
Erin Meyer, DO. and Lynne Uhl, MD
Hypothermia .................................... 440 Hemostatic Abnormalities ........................... 441 Metabolic Abnormalities ............................ 455 Summary ....................................... 463 References ...................................... 463
15 . Complications of Neonatal Transfusion ............. 471
Ross M . Fasano. MD; Wendy M . Paul. MD; and Patricia T. Pisciotto. MD
Metabolic Complications ........................... 472 Immunologic Complications ......................... 498 Summary ....................................... 509 References ...................................... 509
Transfusion Reactions
16 . Adverse Effects of Human-Derived Plasma Derivatives . . 5 1 9
Jeannie Callum, MD. FRCP(C), and Susan Nahirniak, MD, FRCP(C)
....................... Intravenous Immune Globulin 520 .............................. Intravenous Albumin 524 .............................. RhImmuneGlobulin 525
................... Plasma-Derived Coagulation Factors 529 .................... Solvent/Detergent-Treated Plasma 536
...................................... Conclusion 538 References ...................................... 538
17 . Nursing Hemotherapy Bedside Biovigilance in the Recognition and Management of Suspected ........................ Transfusion Reactions 551
Chester Andrzejewski Jr. PhD. MD. and Joan McGirr. RN. BSN. ONC
Important Concepts about Blood Transfusion for the ................. Evaluation and Management of STRs 552
Care Map for Uncomplicated Transfusion Therapy ........ 553 Care Map for Transfusions Associated
........................... with Adverse Sequelae 558 Hemotherapy Documentation in the Electronic
Medical Record: A Potential Avenue for STR ............................ Occurence Mitigation 567
Commonly Encountered Issues and Questions ........... 571 Summary ....................................... 575
...................................... References 576
18 . Detecting and Monitoring Reactions in the Developing World ........................... 579
Cees Th . Smit Sibinga. MD. PhD, FRCP(Ed). FRCPath. and Isaac Ka.aa, M.MED, PhD. FCS(ECSA)
A Baseline Approach to Transfusion Reactions ............ 580 ........................... Global Situation Analysis 580
................ Systems for Detection and Monitoring -582 Obstacles to Effective Detection and Monitoring Systems ... 590
......................... Directions for Improvement 594 References ...................................... 595
xiv
Table of Contents
1 9 . Preventing Transfusion Reactions ................. 597
James R . Stubbs. MD; Kevin L . Bundy. MT(RSCp)SBB; and Camille M . van Buskirk, MD
Transfusion Safety ................................ 598 Transfusion Practices .............................. 624 Now and the Future ............................... 638 Conclusion ...................................... 641 References ...................................... 641
Index .......................................... 649