Dear Colleagues and friends,

We are pleased to announce you this year EUMSand ISMCS societies will hold a joint scientificconference with the common goal to discuss andshare knowledge on mechanical circulatorysupport.

The conference will take place in Hannover(Germany) from December 1 to 4, 2021.

We look forward to welcoming you in Hannover.

Yours faithfully,

The scientific committee

EUMS-ISMCS Joint Meeting P. Leprince, Paris – FRA, A. Loforte, Bologna - ITA

Discussions on directions EUMS-ISMCS group ISMCS President key lecture A. El Banayosy, Oklahoma City - USAEUMS President key lecture J. Schmitto, Hannover - GERWelcome address President of Hannover Medical School M. Manns, Hannover - GERWelcome address Chief of Cardiac Surgery A. Haverich, Hannover - GER

The Development from Heart valves to TAH A. Carpentier, Paris - FRAHistory of MCS in Europe G. Wiesenthaler, Vienna - AUT

WEDNESDAY, DECEMBER 1, 2021

16.00 – 16.30 CETJOINT EUMS-ISMCS OPENING CEREMONY

Chairs: A. El Banayosy, Oklahoma City – USA, A. Loforte, Bologna – ITA, P. Leprince, Paris – FRA, J.Schmitto, Hannover – GER

M. Slepian, Tucson - USA

16.30 – 18.30 CETHELMUT REUL YOUNG INVESTIGATORS SESSION AND GIANT OF MCS

Chairs: P. Leprince, Paris – FRA, U. Steinseifer, Aachen – GER, V. Tchantchaleishvili, Rochester – FRA

18.30 – 21.30 CETWELCOME COCKTAIL IN THE EXHIBITION AREA

MAIN PROGRAMME

Hemocompatility in MCS - The Platelet Perspective 2021 and Beyond M. Slepian, Tucson - USA Proteins, Biomarkers and New Devices C. Bartoli, Philadelphia - USANon-invasive monitoring of HeartMate 3 LVAD patients T. Schlöglhofer, Vienna - AUTHFpEF devices M. Granegger, Vienna - AUTDiscussion

Debate 1

Debate 2

Debate 3

Update recovery: actual status, knowledge and future outlook S. Drakos, Salt Lake City - USAWeaning protocol J. Mulzer, Berlin - GERSport medicine/ Medication to support weaning U. Tegtbur, Hannover - GERBiomechanics of recovery D. Burkhoff, New York - USAFuture outlook: relevance of bio-markers in recovery F. Al Rashid, Essen - GERDiscussion

Transition from ECLS to durable MCS: when and how? A. Loforte, Bologna - ITAAssessing the right ventricle on VA-ECMO D. Donker, Utrecht - NLDDe-escalate and ambulate: from ECMO to Impella C. Napp, Hannover - GERSwitch off the electricity: toward a pneumatic ECMO O. Marseille, Aachen - GEREmergency and ambulatory ECMO C. Schmid, Regensburg - GERDiscussion

THURSDAY, DECEMBER 2, 2021

08:30 – 10:00 CETMCS UNDER THE HOOD

Chairs: L Fresiello, Leuven – BEL, I. Netuka, Prague – CZE, D. Zimpfer, Vienna – AUT

10:30 - 12:30 CETPRO/CONS DEBATES - EUMS - ISMCS

Chairs: A. Haverich, Hannover – GER, F. Moscato, Vienna – AUT, G Wieselthaler, San Francisco - FRA

- Early VAD in chronic heart failure – PRO D. Horstmanshof, Oklahoma City - USA - Early VAD in chronic heart failure – CON J. Bauersachs, Hannover - GER

- Impella and/or ECMO? G. Lebreton, Paris - FRA - Impella and/or ECMO? N. Kapur, Boston - USA

- TAH I. Knesevicz, Ljubljana - SVN - HM6 or Centrifugal TAH M. Strueber, Memphis - USA

13:30 - 15:00 CETRECOVERY

Chairs: E. Birks, Louisville – USA, G. Laufer, Vienna – AUT, M. Morshuis, Bad Oeynhausen - GER

15:30 - 17:00 CETSHORT-TERM SUPPORT

Chairs: A. El Banayosy, Oklahoma City – USA, J. Karimov, Cleveland - USA, S. Mariani, Hannover – GER

Impella 5.5 and BTR: update session T. Siess, Aachen, Abiomed - GERIntelligent systems for long term cardiac monitoring S. Dual, Stanford - USACardiobridge T. Walker, Hechingen - GERProcyrion J. Heuring, Houston - USANuPulse V. Jeevernandam, Chicago - USASyntachK. Solem, Lund - SWEEMKA Medical R. Glocker, Aschaffenburg - GERCorolla Y. Feld, Tel Aviv - ISRBerlin Health J. Muller, Berlin - GERPulsecath O. Malchin, Arnhem - NED

THURSDAY, DECEMBER 2, 2021

17:00 - 18:30 CETFUTURE TECHNOLOGIES I

Chairs: J. Bauersachs, Hannover – GER, G. Lebreton, Paris – FRA, U. Steinseifer, Aachen – GER

Engineering challenges C. Nix, Aachen, Abiomed - GERWhat device for which patients? A. El Banayosy, Oklahoma City - USARefractory CS: from last 3CT meeting A. Mebazza, Paris - FRACovid and short term support: what did we learn? A. Combes, Paris - FRAOther etiologies than AMI and post cardiotomy G. Lebreton, Paris - FRADiscussion

Key note lecture: the use of isolated RVADs E. Rame, Philadelphia - USAThe failing RV in the setting of LVAD O. Soliman, Galway - IRLClinical experiences with (oxy) RVADs R. Lorusso, Maastricht - NLDRotary pump for RVAD J. Lavee, Tel Aviv - ISRPulsatile RVAD trial sponsor B. Schmack, Essen - GERUniversal ventricular assist device J. Karimov, Cleveland - USA

Carmat P. Leprince, Paris - FRASyncardia G. Tenderich, Hawaii - USAReal heart I.-L. Perkins, Västerås, Real Heart - SWEBivacor D. Timms, Sydney, Bivacor - AUSCleveland heart J. Karimov, Cleveland - USABiological TAH: padua project G. Gerosa, Padua - ITA

FRIDAY, DECEMBER 3, 2021

09:00 - 10:30 CETACUTE SESSION: SHORT TERM

Chairs: P. Leprince, Paris – FRA, R. Lorusso, Maastricht – NLD, A. Loforte, Bologna – ITA, B. Kuban,Cleveland – USA

10:30 - 12:30 CETRVAD and BVAD

Chairs: A. Loforte, Bologna – ITA, E. Potapov, Berlin – GER, J. Riebandt, Vienna – AUT

10:30 - 12:30 CETTAH UPDATE

Chairs: G. Dogan, Hannover - GER, M. Slepian - USA, D. Wiedemann, Vienna - AUS

GALA DINNER

Impact of device withdrawal - the bad, the ygly and the good ? M. Slepian, Tucson - USAMarket development J. Long, Oklahoma City - USAOutcome variation through centers N. Uriel, New York - USADiscussion

FRIDAY, DECEMBER 3, 2021

15:30 - 17:00 CETMARKET DEVELOPMENT AND FUTURE OF MCS

Chairs: P. Leprince, Paris – FRA, J. Long, Oklahoma City – USA, J. Schmitto, Hannover – GER, U.Steinseifer, Aachen – GER, N. Uriel, New York – USA

17:00 - 19:00 CETVAD UPDATES

Is antiplatellet necessary for HMIII patients?

HEMO compatibility the Big Picture : now and in the future M. Slepian, Tucson - USADiscussion

Key note lecture: on control strategies H. Schima, Vienna - AUSHemodynamic limitations and challenges in LVAD technology L. Fresiello, Leuven - BELESAO communicationESAO communication

Keynote lecture: what we expect from the future? J. Schmitto, Hannover - GERXenotransplantation: Where we are today? B. Reichart, Hannover - GERTotal bioartificial heart: science or fiction? G. Luraghi, Milan - ITARobotics Z. Khalpey Tucson - USAHow far can we go with miniaturization? U. Steinseifer, Aachen - GER Mechanical circulatory support for HFpEF B. Kuban, Cleveland - USA

Awards Presentation of EUMS 2022 (Paris, France) P. Leprince, Paris - FRAPresentation of ISMCS 2022 (USA) A. El Banayosy, Oklahoma City - USAClosing ceremony J. Schmitto, Hannover - GER

SATURDAY, DECEMBER 4, 2021

09:00 - 10:30 CETEUMS-ISMCS-ESAO

Chairs: U. Steinseifer, Aachen – GER, Jacobs - BEL, M. Slepian, Tucson – USA

- Con I. Netuka, Prague - CZE - Pro C. Bartoli, Philadelphia - USA

11:00 – 12:30 CETWHAT IS THE NEXT STEP?

Chairs: E. Rame, Philadelphia – USA, M. Slepian, Tucson – USA, G. Laufer, Vienna – AUT

12:30 – 13:30 CETEUMS-ISMCS CLOSING CEREMONY

Chairs: A. El Banayosy, Oklahoma City – USA, A. Loforte, Bologna – ITA, J. Schmitto, Hannover – GER, M. Slepian, Tucson – USA

The Role of the VAD Coordinator: US Perspective E. Davis, Utah - USAThe Role of the VAD Coordinator: EU Perspective S. Boschi, Bologna - ITAAnticoagulation Practices in LVAD Patients F. Müller, Homburg - GERSpecial patients - special databases S. Fischer, Hannover - GER

Enhanced technical patient management: logfiles, acoustic analysis and more

Telemonitoring VAD patients COVID-19

VAD STAT App – Algorithm based assessment tool for low frequency MCS providers

Driveline Infections: Surgical remediation and alternatives A. Schöde - K.Homann, Hannover - GERDriveline management with cold plasma therapy R. Bach, Bad Rothenfelde - GERNon-durable MCS strategies – impact of the new US allocation J. Hajj, Charleston - USACardiac Rehabilitation of LVAD patients K. Vandersmissen, Leuven - BELStaying Active on an LVAD S. Kore, Manchester - GBRPalliative Care in LVAD patients A.-M. Oppelaar, Utrecht - NLDAlternative ways of carrying backpacks for VAD patients F. Fatteicher -GER

Welcome and overview J. Schmitto, Hannover - GERMy >5 years with the MVAD R. Laukart, Hannover - GER·>7 years with Heartmate 3 - report of the worldwide first HM3-patient K. Müller, Hannover - GERAlmost 10 years support with HVAD J. Böckelmann, Hannover - GEROutpatient management H. Niehaus, Hannover - GERStaying Active on an LVAD U. Tegtbur, Hannover - GERCardiac Rehabilitation of LVAD patients S. Brunner, Bad Fallingbostel - GERAlternative ways of carrying backpacks for VAD patients F. Fatteicher - GER

WEDNESDAY, DECEMBER 1, 2021

13:00 – 14:30 CETVAD Coordinator meetingRole of the VAD Coordinator and management

Chairs: S. Mariani, Maastricht – BEL, A. Schöde, Hannover – GER

14:45 – 15:45 CETVAD Coordinator meetingTechnical supervision in times of COVID-19

Chairs: E. Davis, Utah – USA, T. Schlöglhofer, Vienna - AUT

F. Kaufmann, Berlin - GER

V. Lauenroth, Bad Oeynhausen - GER

T. Robbins, Philadelphia - USA

THURSDAY, DECEMBER 2, 2021

10:00 – 12:30 CETVAD Coordinator meetingDriveline Infection /Patient Management

Chairs: H. Niehaus, Hannover – GER, F. Müller, Homburg - GER

13:30 – 16:00 CETRapid-fire abstracts session

13:30 – 16:00 CETVAD-Patient-Meeting

PARALLEL ROOMS

RNA-based therapies for heart failure T. Thum, Hannover - GERMolecular imaging of the failing heart and device-related complications F. M. Bengel, Hannover - GERCell-therapy for pulmonary arterial hypertension and heart failure alternativ

Ex-vivo cardiac surgery using the OCS-system A. Martens, Hannover - GERProtein based therapies for myocardial infarction K.C. Wollert, Hannover - GERIron deficiency aggravates heart failure T. Kempf, Hannover - GEROverview of existing large animal models in Hannover T.Meyer, Hannover - GER

Welcome address J. Schmitto, Hannover - GERPreoperative optimization of the patients scheduled for LVAD implantation

Surgical implantation techniques and recommendations J. Hanke, Hannover - GERCoagulation disorders prior to LVAD implantation H. Berg Ravn, Odense - DENIntraoperative hemodynamic management N. Marczin, Harefield - GBRVasoplegia after LVAD implantation E. de Waal, Utrecht - NLDStrategies for early postoperative recovery E. Tschernko, Vienna - AUT

FRIDAY, DECEMBER 3, 2021

09:00 – 10:30 CETEcho-course on VAD-patients

09:00 – 10:30 CETJoint session EUMS-KFO311Perfusionist meeting

Chairs: J. Bauersachs, Hannover – GER, S. Cebotari, Hannover - GER

U. Martin, Hannover - GER

11:00 - 12:30 CETJoint session EUMS/ISMCS and EACTAIC Interdisciplinary session LVAD implantationPerioperative management of ventricular assist devices

Chairs: N. Marczin, GBR, R. Schramm, Bad Oeynhausen - GER

C. Stoppe, Würzburg - GER

15:30 – 17:00 CETRapid-fire abstracts session