Synchrony and metastable coordination dynamics in human brain activity
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Transcript of Synchrony and metastable coordination dynamics in human brain activity
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SYNCHRONY AND METASTABLE COORDINATION DYNAMICS IN HUMAN BRAIN ACTIVITY
Emmanuelle Tognoli & J. A. Scott Kelso
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Attention is an integrative brain function: requires multiple brain areas to coordinate
with one another.
We present a theoretical & methodological framework for the analysis of coordination
between brain areas.
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Phase f of an oscillation
For two oscillations, xt and yt
rpt=f(xt)-f(yt)
If rpt=rpt+1=rpt+2…
Oscillations are phase-locked
time
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Coordination dynamics between brain areas
Tognoli & Kelso, in press, Progress in Neurobiology
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Predicting true and false synchrony
2 or more sources
Coordinated inphase
Coordinated antiphase
Coordinated out of phase
Metastable
Uncoordinated
1 cortical sourceSulcal
Gyral
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Generalization: amplitude and phase biases
Amplitude of EEG signal does not speak of amplitude of the sources
Inphase (zero-lag) synchrony of EEG signal does not mean inphase between the sources
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Spatio-temporal patterns in continuous EEG
False antiphaseFalse inphase
Real out-of-phase locking
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Interim conclusions
Real synchrony is rare and brief.
Data suggest that most coordination dynamics in the brain is metastable, (not synchronized states).
Theoretical Methodological
Usefulness of time-aggregated coherence studies directly depends on the ratio between real and false synchrony.
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Diversity of 10Hz rhythms in human waking EEG
Tognoli & Kelso, in prep
xpeak at 12Hzleft CPERS
apeak at 11Hz
POERD
“a paradox”
Seen during covert spatial attention task
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Covert shift of attention
up(endogenous)
15 secAttention
maintained on fixation
5 sec
Covert shift of attention
down(endogenous)
15 sec
100 msec
19.7% 17% 21.1%
control
7.2%
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Attention: “Attendere”: to stretch, to tend
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PHASE-LOCKED BRAIN STATES: SPECIFIC FOR ATTENTION?
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SUPPORT CONTRIBUTED BY
Accepting email applicationsPostdoctoral Associate
Social Coordination Dynamicswww.ccs.fau.edu/hbbl.html