2010 IEEE International

Symposium on Biomedical

Imaging: From Nano to Macro

(ISBI2010)

Rotterdam, Netherlands

14-17 April 2010

Pages 1-699 [_ A~]

IPCC IEEE Catalog Number: CFP10BIS-PRTItEt ISBN: 978-1-4244-4125-9

1/2

Table of Contents

Volume

WE-PSl: VASCULAR IMAGE ANALYSIS

WE-PS1.1: ULTRASONOGRAPHIC PLAQUE CHARACTERIZATION USING A RAYLEIGH 1

MIXTURE MODEL

Jose Seabra, Joao Sanches, Institute) Superior Tecnico, Portugal; Francesco Ciompi, Petia Radeva, Universitat

de Barcelona, Spain

WE-PS1.2: IMPROVING HARD EXUDATE DETECTION IN RETINAL IMAGES 5

THROUGH A COMBINATION OF LOCAL AND CONTEXTUAL INFORMATION

Clara I. Sanchez, Meindert Niemeijer, Image Sciences Institute, University Medical Center Utrecht,

Netherlands; Maria S. A. Suttorp Schulten, Ophthalmology Service, Netherlands; Michael Abramoff,

Ophthalmology and Visual Sciences, United States; Bram van Ginneken, Image Sciences Institute, UniversityMedical Center Utrecht, Netherlands

WE-PS1.3: A PATIENT-SPECIFIC CORONARY DENSITY ESTIMATE 9

Rahil Shahzad, Delft University of Technology, Netherlands; Michiel Schaap, Theo van Walsum, Stefan Klien,

Annick Weustink, Erasmus MC - University Medical Center Rotterdam, Netherlands; Lucas van Vliet, DelftUniversity of Technology, Netherlands; Wiro Niessen, Erasmus MC - University Medical Center Rotterdam,Netherlands

WE-PS1.4: AUTOMATED CAROTID ARTERY DISTENSIBILITY MEASUREMENTS 13

FROM CTA USING NONRIGID REGISTRATION

Reinhard Hameeteman, Biomedical Imaging Group Rotterdam, Departments ofRadiology & Medical

Informatics Erasmus MC, Netherlands; Sietske Rozie, Coert Metz, Stefan Klein, Theo Walsum, van, Aad Lugt,

van der, Erasmus MC - University Medical Center Rotterdam, Netherlands; Wiro Niessen, Biomedical Imaging

Group Rotterdam, Departments ofRadiology & Medical Informatics Erasmus MC, Netherlands

WE-PS1.5: CORONARY VEIN TRACKING FROM MSCT USING A MINIMUM COST 17

PATH APPROACH

Marie-Paule Garcia, Christine Toumoulin, Pascal Haigron, Jerome Velut, Mireille Garreau, Universite de

Rennes I, France; Dominique Boulmier, CHU Rennes, France

WE-PS1.6: EVALUATING DEFORMATION PATTERNS OF THE AORTA IN CTA 21

SEQUENCESErnst Schwartz, Roman Gottardi, Johannes Holfeld, Christian Loewe, Martin Czerny, Medical University

Vienna, Austria; Georg Langs, Massachusetts Institute ofTechnology, United States

WE-PS1.7: SERIAL NONRIGID VASCULAR REGISTRATION USING WEIGHTED 25

NORMALIZED MUTUAL INFORMATION

Jung W. Suh, Dustin Scheinost, Yale University, United States; Xiaoning Qian, University ofSouth Florida,United States; Albert Sinusas, Christopher Breuer, Xenophon Papademetris, Yale University, United States

ix

WE-PS1.8: MULTI-SCALE APPROACH FOR RETINAL VESSEL SEGMENTATION 29

USING MEDIALNESS FUNCTION

Elahe Moghimirad, Seyed Hamid Rezatofighi, Hamid Soltanian-Zadeh, University of Tehran, Iran

WE-PS1.9: INFLUENCE OF VESSEL ROUGHNESS ON WALL SHEAR STRESS IN 33

IMAGE-BASED BLOOD FLOW MODELING

Guanglei Xiong, Charles Taylor, Stanford University, United States

WE-PS1.10: 3D CORONARY STRUCTURE TRACKING ALGORITHM WITH 37

REGULARIZATION AND MULTIPLE HYPOTHESES IN MRI

Jerome Velut, Christine Toumoulin, Jean-Louis Coatrieux, LTSI - INSERM U642, France

WE-PS1.11: ADAPTIVE INTENSITYMODELS FOR PROBABILISTIC TRACKING OF 3D 41

VASCULATURE

Fei Zhao, Rahul Bhotika, Paulo Mendonca, Nils Krahnstoever, James V. Miller, GE Global Research, United

States

WE-PS1.12: AUTOMATIC GLOBAL VESSEL SEGMENTATION AND CATHETER 45

REMOVAL USING LOCAL GEOMETRY INFORMATION AND VECTOR FIELD

INTEGRATION

Matthias Schneider, Friedrich-Alexander University, Germany; Hari Sundar, Siemens Corporate Research,United States

WE-PS1.13: FRACTAL MODELLING AND ANALYSIS OF FLOW-FIELD IMAGES 49

Pouya Tafti, Ricard Delgado-Gonzalo, Ecole Polytechnique Federate de Lausanne (EPFL), Switzerland;Aurelien Stalder, University Hospital Freiburg, Germany; Michael Unser, Ecole Polytechnique Federale de

Lausanne (EPFL), Switzerland

WE-PS1.14: A DYNAMIC RECONSTRUCTION APPROACH FOR CEREBRAL BLOOD 53

FLOW QUANTIFICATION WITH AN INTERVENTIONAL C-ARM CTAndreas Fieselmann, University Erlangen-Nuremberg, Germany; Arundhuti Ganguly, Stanford University,United States; Yu Deuerling-Zheng, Michael Zellerhojf, Jan Boese, Siemens AG, Germany; Joachim

Hornegger, University Erlangen-Nuremberg, Germany; Rebecca Fahrig, Stanford University, United States

WE-PS2: BRAIN IMAGING AND ANALYSIS I

WE-PS2.1: ROBUSTNESS AND SENSITIVITY OF HOTELLING'S T2-BASED 57

PERMUTATION TESTS FORSELECTION OF 3D MORPHOLOGICAL MARKERSLuca Ferrarini, Leiden University Medical Center, Netherlands; Giovanni B. Frisoni, Michela Pievani,Rossana Ganzola, IRCCS San Giovanni di Dio-FBF, Italy; Johan H.C. Reiber, Julien Milles, Leiden UniversityMedical Center, Netherlands

WE-PS2.2: MULTI-CONTRAST DEEPNUCLEI SEGMENTATION USING A 61PROBABILISTICATLASLinda Marrakchi-Kacem, Cyril Poupon, Jean-Franqois Mangin, Fabrice Poupon, CEA, France

WE-PS2.3: WHICH BRAINSTEM CELLS GENERATE THE RESPIRATION CYCLES? 65Allison W. Irvine, Florida International University, United States; Sotirios Chatzis, Gavriil Tsechpenakis,University ofMiami, United States

x

WE-PS2.4: ADAPTIVE WEIGHTED FUSION OF MULTIPLE MR SEQUENCES FOR 69

BRAIN LESION SEGMENTATION

Florence Forbes, Senan Doyle, INRIA Grenoble Rhone-Alpes, UK, France; Daniel Garcia-Lorenzo, Christian

Barillot, INRIA Rennes Bretagne Atlantique, France; Michel Dojat, INSERM, France

WE-PS2.5: TEMPLATE METHOD TO IMPROVE BRAIN SEGMENTATION FROM 73

INHOMOGENEOUS BRAIN MAGNETIC RESONANCE IMAGES AT HIGH FIELDS

Marcelo Castro, Jianhua Yao, Yuxi Pang, Eva Baker, John Butman, David Thomasson, National Institutes ofHealth, United States

WE-PS2.6: A REACTION-DIFFUSION MODEL OF THE HUMAN BRAIN 77

DEVELOPMENT

Julien Lefevre, LSIS, UMR CNRS 6168, Universite Aix-Marseille II, France; Jean-Franqois Mangin, CEA,I2BM, Neurospin, France

WE-PS2.7: EARLY ALZHEIMER'S DISEASE DIAGNOSIS USING PARTIAL LEAST 81

SQUARES AND RANDOM FORESTS

Javier Ramirez, Juan M. Gorriz, Fermm Segovia, Rosa Chaves, Diego Salas-Gonzalez, Miriam Lopez, IgnacioAlvarez, Pablo Padilla, University of Granada, Spain

WE-PS2.8: APPROXIMATING TUMOR INDUCED BRAIN DEFORMATION USING 85

DIRECTLY MANIPULATED FREE FORM DEFORMATION

Stefan Becker, Andreas Mang, Alina Toma, Thorsten M. Buzug, University ofLiibeck, Germany

WE-PS2.9: UNSUPERVISED SEGMENTATION OF BRAIN TISSUE IN MULTIVARIATE 89

MRI

Alexandra Constantin, Ruzena Bajcsy, University of California, Berkeley, United States; Sarah Nelson,

University of California, San Francisco, United States

WE-PS2.10: AUTOMATED SEGMENTATION OF BRAIN LESIONS BY COMBINING 93

INTENSITY AND SPATIAL INFORMATION

Bilwaj Gaonkar, Guray Erus, Nick Biyan, Christos Davatzikos, University ofPennsylvania, United States

WE-PS2.11: A NEW FRAMEWORK FOR ANALYZING WHITE MATTER MATURATION 97

IN EARLY BRAIN DEVELOPMENT

Marcel Prastawa, NedaSadeghi, University of Utah, United States; John Gilmore, WeiliLin, University ofNorth Carolina, United States; Guido Gerig, University of Utah, United States

WE-PS2.12: A GENETIC ANALYSIS OF CORTICAL THICKNESS IN 372 TWINS 101

AnandA. Joshi, University of California, Los Angeles, United States; Natasha Lepore, University of Southern

California, United States; Shantanu Joshi, Agatha D. Lee, Marina Barysheva, University of California, Los

Angeles, United States; Greig I. de Zubicaray, University ofQueensland, Australia; Margaret J. Wright,Queensland Institute ofMedical Research, Australia; Katie L. McMahon, University of Queensland, Australia;Arthur Toga, Paul M. Thompson, University of California, Los Angeles, United States

WE-PS2.13: AUTOMATIC VOLUMETRY CAN REVEAL VISUALLY UNDETECTED 105

DISEASE FEATURES ONBRAIN MR IMAGES IN TEMPORAL LOBE EPILEPSY

Shiva Keihaninejad, Rolf A. Heckemann, Ioannis S. Gousias, Paul Aljabar, Joseph V. Hajnal, Daniel Rueckert,Alexander Hammers, Imperial College London, United Kingdom

xi

WE-PS2.14: IMAGE-BASED DETECTION OF CORPUS CALLOSUM VARIABILITY FOR 109

MORE ACCURATE DISCRIMINATION BETWEEN DYSLEXIC AND NORMAL

BRAINS

Ahmed Elnakib, Ayman El-Baz, Biolmaging Laboratory, University ofLouisville, United States; Manuel

Casanova, University ofLouisville, United States; Georgy Gimel'farb, University ofAuckland, New Zealand;

Andrew Switala, University ofLouisville, United States

WE-PS2.15: CANONICAL CORRELATION ANALYSIS APPLIED TO FUNCTIONAL 113

CONNECTIVITY IN MEG

Juan L.P. Soto, Dimitrios Pantazis, University ofSouthern California, United States; KarimJerbi, University

Lyon 1, France; Sylvdin Baillet, Medical College of Wisconsin, United States; Richard M. Leahy, University of

Southern California, United States

WE-PS3: BIOLOGICAL IMAGING AND ANALYSIS I

WE-PS3.1: PAPSYNTH: SIMULATED BRIGHT-FIELD IMAGES OF CERVICAL SMEARS 117

Patrik Malm, Anders Brun, Ewert Bengtsson, Uppsala University, Sweden

WE-PS3.2: GAUSSIAN MIXTURES FOR INTENSITY MODELING OF SPOTS IN 121

MICROSCOPY

Kangyu Pan, Anil Kokaram, Jens Hillebrand, Mani Ramaswami, Trinity College Dublin, Ireland

WE-PS3.3: CELL SEGMENTATION IN MICROSCOPY IMAGERY USING A BAG OF 125

LOCAL BAYESIAN CLASSIFIERS

Zhaozheng Yin, Ryoma Bise, Carnegie Mellon University, United States; Mei Chen, Intel Labs Pittsburgh,United States; Takeo Kanade, Carnegie Mellon University, United States

WE-PS3.4: A GRAPH-BASED METHOD FOR DETECTING CHARACTERISTIC 129

PHENOTYPES FROM BIOMEDICAL IMAGES

Wei Wang, Cheng Chen, Tao Peng, Dejan Slepcev, Carnegie Mellon University, United States; John A. Ozolek,Children's Hospital ofPittsburgh, United States; Gustavo Rohde, Carnegie Mellon University, United States

WE-PS3.5: DISCRIMINATIVE SPARSE REPRESENTATIONS FOR CERVIGRAM IMAGE 133

SEGMENTATION

Shaoting Zhang, Junzhou Huang, Rutgers, The State University ofNew Jersey, United States; Wei Wang,Xiaolei Huang, Lehigh University, United States; Dimitris Metaxas, Rutgers, The State University ofNew

Jersey, United States

WE-PS3.6: DETECTION OF HEMATOPOIETIC STEM CELLS IN MICROSCOPY 137

IMAGES USING A BANK OF RING FILTERS

Sungeun Eom, Ryoma Bise, Takeo Kanade, Carnegie Mellon University, United States

WE-PS3.7: NONPARAMETRIC SEGMENTATION AND CLASSIFICATION OF SMALL 141

SIZEIRREGULARLY SHAPED STEM CELL NUCLEI USING ADJUSTABLE

WINDOWING

Nathan Lowry, Massachusetts Institute ofTechnology / Draper Laboratory, United States; Rami Mangoubi,Mukund Desai, The Charles Stark Draper Laboratory, Inc., United States; Paul Sammak, University ofPittsburgh, United States

WE-PS3.8: METAMERISM IN MULTISPECTRAL IMAGING OF HISTOPATHOLOGY 145

SPECIMENS

William Cukierski, David Foran, University ofMedicine and Dentistry ofNew Jersey, United States

xii

WE-PS3.9: KI-67 HOT-SPOTS DETECTION ON GLIOBLASTOMA TISSUE SECTIONS 149

Xavier Moles Lopez, Olivier Debeir, Universite Libre de Bruxelles, Belgium; Calliope Maris, Isabelle Roland,Isabelle Salmon, Erasmus Hospital, Universite Libre de Bruxelles, Belgium; Christine Decaestecker, Universite

Libre de Bruxelles, Belgium

WE-PS3.10: GRAPH-BASED MULTI-RESOLUTION SEGMENTATION OF 153

HISTOLOGICAL WHOLE SLIDE IMAGES

Vincent Roullier, Vinh-Thong Ta, Olivier Lezoray, Abderrahim Elmoataz, GREYC-UMR-CNRS 6072, France

WE-PS3.11: IMPROVED AUTOMATED LOCALIZATION AND QUANTIFICATION OF 157

PROTEIN MULTIPLEXES VIA MULTISPECTRAL FLUORESCENCE IMAGING IN

HETEROGENOUS BIOPSY SAMPLES

Marina Sapir, Faisal Khan, Yevgen Vengrenyuk, Gerardo Fernandez, Ricardo Mesa-Tejada, Stefan Hamman,Mikhail Teverovskiy, Michael Donovan, Aureon Laboratories, Inc, United States

WE-PS3.12: A GENERAL APPROACH FORSEGMENTING ELONGATED AND STUBBY 161

BIOLOGICAL OBJECTS: EXTENDING A CHORD LENGTH TRANSFORM WITH

THE RADON TRANSFORM

QuanXue, Nick Jones, Mark Leake, University of Oxford, United Kingdom

WE-PS3.13: MULTIPHASE LEVEL SET FOR AUTOMATED DELINEATION OF 165

MEMBRANE-BOUND MACROMOLECULES

Hang Chang, Bahrain Parvin, Lawrance Berkeley National Laboratory, United States

WE-PS3.14: CLASSIFICATION BY BOOTSTRAPPING IN SINGLE PARTICLE 169

METHODS

Hstau Y. Liao, Joachim Frank, Columbia University, United States

WE-PS4: CANCER IMAGING AND ANALYSIS

WE-PS4.1: DETECTION AND RETRIEVAL OF CYSTS IN JOINT ULTRASOUND 173

B-MODE AND ELASTICITYBREAST IMAGES

Jingdan Zhang, Shaohua Zhou, Shelby Brunke, Carol Lowery, Dorin Comaniciu, Siemens, United States

WE-PS4.2: CELL-BASED GRAPH CUT FOR SEGMENTATION OF 2D/3D 177

SONOGRAPHIC BREAST IMAGES

Hsin-Hung Chiang, Jie-Zhi Cheng, Pei-Kai Hung, Chun-You Liu, Cheng-Hong Chung, Chung-Ming Chen,

National Taiwan University, Taiwan

WE-PS4.3: INTERPRETING ULTRASOUND ELASTOGRAPHY: IMAGE REGISTRATION 181

OF BREAST CANCER ULTRASOUND ELASTOGRAPHY TO HISTOPATHOLOGY

IMAGES

Brian Chuang, University of Oxford, United Kingdom; Andriy Myronenko, Oregon Health & Science

University, United States; Ruth English, Oxford Radclijfe Hospitals NHS Trust, United Kingdom; Alison Noble,

University of Oxford, United Kingdom

WE-PS4.4: PHARMACOKINETIC MODELS IN CLINICAL PRACTICE: WHAT MODEL 185

TO USE FOR DCE-MRI OF THE BREAST?

Geert Litjens, Marieke Heisen, Eindhoven University of Technology, Netherlands; Johannes Buurman, PhilipsHealthcare, Netherlands; Bart M. ter Haar Romeny, Eindhoven University of Technology, Netherlands

xiii

WE-PS4.5: A REGION-BASED ACTIVE CONTOUR METHOD FOR EXTRACTION OF 189

BREAST SKIN-LINE IN MAMMOGRAMS

Sheshadri Thiruvenkadam, Mausumi Achaiya, Neeba NV, Priyavrat Jhunjhunwala, Sohan Ranjan, General

Electric, India

WE-PS4.6: APPEARANCE ANALYSIS FOR DIAGNOSING MALIGNANT LUNG NODULES 193

Ayman El-baz, Biobnaging Laboratory, University ofLouisville, United States; Georgy Gimel'farb, University

ofAuckland, New Zealand; Robert Falk, Jewish Hospital, Louisville, Kentucky, United States; Mohamed El-

Ghar, University ofMansoura, Egypt

WE-PS4.7: MAMMOGRAPHIC IMAGE CLASSIFICATION USING HISTOGRAM 197

INTERSECTION

Erkang Cheng, Nianhua Xie, Haibin Ling, Temple University, United States; Predrag Bakic, Andrew Maidment,

University ofPennsylvania, United States; Vasileios Megalooikonomou, Temple University, United States

WE-PS4.8: GENERALIZED OPTIMAL QUANTITATIVE INDEX OF DUAL-TIME 201

FDG-PET IMAGING IN LUNG CANCER DIAGNOSIS

Xiujuan Zheng, Guangjian Tian, The Hong Kong Polytechnic University, Hong Kong SAR of China; Lingfeng

Wen, Royal Prince Alfred Hospital, Australia; David Dagan Feng, The Hong Kong Polytechnic University,

Hong Kong SAR ofChina

WE-PS4.9: MODELING THERMOGRAPHY OF THE TUMOROUS HUMAN BREAST: 205

FROM FORWARD PROBLEM TO INVERSE PROBLEM SOLVING

Li Jiang, George Washington University, United States; Wang Zhan, University of California, San Francisco,

United States; Murray Loew, George Washington University, United States

WE-PS4.10: ANADAPTIVE TRACKING ALGORITHM OFLUNG TUMORS IN 209

FLUOROSCOPY USING ONLINE LEARNED COLLABORATIVE TRACKERS

Baiyang Liu, Rutgers, The State University ofNew Jersey, United States; Lin Yang, University ofMedicine

and Dentistry ofNew Jersey, United States; Casimir Kulikowski, Rutgers, The State University ofNew Jersey,United States; Jinghao Zhou, University ofMedicine and Dentistry ofNew Jersey, United States; Leiguang

Gong, IBM T. J. Watson Research Center, United States; David Foran, Salma Jabbour, Ning Yue, University of

Medicine and Dentistry ofNew Jersey, United States

WE-PS4.11: TWIN TARGET CORRECTION FOR ULTRA-WIDEBAND RADAR IMAGING 213

OF BREAST TUMOURS

Jean-Francois Deprez, University of Oxford, United Kingdom; Maciek Klemm, University of Bristol, United

Kingdom; Penny Probert Smith, University of Oxford, United Kingdom; Ian Craddock, University ofBristol,United Kingdom

WE-PS4.12: JOINT VARIATIONAL SEGMENTATION OF CT-PET DATA FOR TUMORAL 217

LESIONS

Julien Wojak, Elsa D. Angelini, Isabelle Bloch, Telecom ParisTech, France

WE-PS4.13: PROBABILISTIC BRANCHING NODE DETECTION USING ADABOOST 221

AND HYBRID LOCAL FEATURES

Tatyana Nuzhnaya, Michael Bamathan, Haibin Ling, Vasileios Megalooikonomou, Temple University, United

States; Predrag Bakic, Andrew Maidment, University ofPennsylvania, United States

WE-PS4.14: EXEMPLAR-BASED SEGMENTATION OF PIGMENTED SKIN LESIONS 225FROMDERMOSCOPY IMAGES

Howard Zhou, James M. Rehg, Georgia Institute of Technology, United States; Mei Chen, Intel Labs

Pittsburgh, United States

xiv

WE-PS4.15: PREDICTING CLASSIFIER PERFORMANCE WITH A SMALL TRAINING 229

SET: APPLICATIONS TO COMPUTER-AIDED DIAGNOSIS AND PROGNOSIS

Ajay Basavanhally, Scott Doyle, Anant Madabhushi, Rutgers, The State University ofNew Jersey, United States

WE-PS4.16: SINGLE-VIEW 2D/3D REGISTATION FOR X-RAY GUIDED 233

BRONCHOSCOPY

Di Xu, Johns Hopkins University, United States; Sheng Xu, Philips Research North America, United States;Daniel A. Herzka, Johns Hopkins University, United States; Rex Yung, Johns Hopkins Medical Institutions,

United States; Martin Bergtholdt, Philips Research North Europe, Germany; Luis F. Gutierrez, Image Guided

Interventions, Philips Healthcare, United States; Elliot R. McVeigh, Johns Hopkins University, United States

WE-OS1: BRAIN IMAGING AND ANALYSIS

WE-OS1.1: A RIEMANNIAN MODEL OF REGIONAL DEGENERATION OF THE 237

HIPPOCAMPUS IN ALZHEIMER'S DISEASE

Xiuwen Liu, Florida State University, United States; Yonggang Shi, University ofCalifornia, Los Angeles,United States; Ying Wang, Florida State University, United States; Paul M. Thompson, University of California,Los Angeles, United States; Washington Mio, Florida State University, United States

WE-OS1.2: VENTRICULARMAPS IN 804 SUBJECTS CORRELATE WITH COGNITIVE 241

DECLINE, CSF PATHOLOGY, AND IMMINENT ALZHEIMER'S DISEASE

Yi-Yu Chou, Natasha Lepore, Priya Saharan, Sarah Madsen, Xue Hua, University of California, Los Angeles,United States; Clifford Jack, Mayo Clinic, United States; Leslie Shaw, JohnTrojanowski, University of

Pennsylvania, United States; Michael Michael W. Weiner, University of California, San Francisco, United

States; Arthur Toga, PaulM. Thompson, University of California, Los Angeles, United States

WE-OS1.3: IN VIVO BRAIN ELASTICITY MAPPING IN SMALL ANIMALS USING 245

ULTRASOUND AND ITS APPLICATION TO CEREBRAL ISCHEMIA

Emilie Mace, Institut Langevin, France; Ivan Cohen, Cortex et epilepsie, France; Abraham Martin, CEA,

France; Gabriel Montaldo, Mathias Fink, Institut Langevin, France; Bertrand Tavitian, CEA, France; Mickael

Tanter, Institut Langevin, France

WE-OS1.4: EARLY DIAGNOSIS OF DEMENTIA BASED ON INTERSUBJECT 249

WHOLE-BRAIN DISSIMILARITIES

Stefan Klein, Erasmus MC - University Medical Center Rotterdam, Netherlands; Marco Loog, Delft University

of Technology, Netherlands; Fedde van derLijn, Tom den Heijer, Erasmus MC - University Medical Center

Rotterdam, Netherlands; Alexander Hammers, Neurodis Foundation, France; Marleen de Bruijne, Aad van

der Lugt, Erasmus MC - University Medical Center Rotterdam, Netherlands; Robert Duin, Delft Universityof Technology, Netherlands; Monique Breteler, Wiro Niessen, Erasmus MC - University Medical Center

Rotterdam, Netherlands

WE-OS2: MR IMAGING

WE-OS2.1: A SPARSE BAYESIAN LEARNING FOR HYGHLY ACCELERATED DYNAMIC 253

MRI

Hong Jung, Jong Chul Ye, Korea Advanced Institute of Science and Technology, Republic ofKorea

WE-OS2.2: AN ACCELERATED ITERATIVE REWEIGHTED LEAST SQUARES 257

ALGORITHM FOR COMPRESSED SENSING MRI

Sathish Ramani, Jeffrey Fessler, University of Michigan, United States

XV

WE-OS2.3: ANALYTICAL FORM OF SHEPP-LOGAN PHANTOM FOR PARALLEL MRI 261

Matthieu Guerquin-Kern, Fikret Isik Karahanoglu, Dimitri Van De Ville, Ecole Polytechnique Federale

de Lausanne (EPFL), Switzerland; Klaas Pruessmann, ETH Zurich, Switzerland; Michael Unser, Ecole

Polytechnique Federale de Lausanne (EPFL), Switzerland

WE-OS2.4: A FAST & ACCURATE NON ITERATIVE ALGORITHM FORREGULARIZED 265

NON CARTESIAN MRI

Satyananda Kashyap, Mathews Jacob, University ofRochester, United States

WE-SS1: COMPUTER AIDED DIAGNOSIS

WE-SS1.1: CURRENT CONCEPTS IN COMPUTER-AIDED DETECTION FOR CT 269

COLONOGRAPHY

Ronald Summers, National Institutes ofHealth, United States

WE-SS1.2: COMPUTER AIDED DETECTION IN BREAST IMAGING: MORE THAN A 273

PERCEPTION ADD.

Nico Karssemeijer, Radboud University Nijmegen Medical Centre, Netherlands

WE-SS1.3: COMPUTER-AIDED DIAGNOSIS IN CHEST IMAGING: HOW TO 274

IMPROVE PERFORMANCE AND AVOID REINVENTING THE WHEEL

Bram van Ginneken, Image Sciences Institute, University Medical Center Utrecht, Netherlands

WE-SS1.4: COMPUTER-ASSISTANCE IN NEUROIMAGING: FROM QUANTITATIVE 275

IMAGEANALYSIS TO COMPUTER-AIDED DIAGNOSIS

Horst Karl Halm, Fraunhofer MEVIS, Germany

WE-SS2: ULTRASOUND IMAGING AND ANALYSIS

WE-SS2.1: REAL TIME QUANTITATIVE ELASTOGRAPHY USING SUPERSONIC 276

SHEAR WAVE IMAGING

Michael Tanter, Mathieu Pernot, Gabriel Montaldo, Jean Luc Gennisson, Eric Bavu, Emilie Mace, Thu-Mai

Nguyen, Mathieu Couade, Mathias Fink, Langevin Institute (CNRS UMR 7587), Inserm U979, France

WE-SS2.2: ROBUST ULTRASOUND IMAGE ANALYSIS USING LEARNING 280

Dorin Comaniciu, Siemens Corporate Research, United States

WE-SS2.3: INTRAVASCULAR ULTRASOUND: ASSESSMENT OF ATHEROSCLEROSIS 281

Antonius FW van der Steen, Gijs van Soest, Marcia Emmer, David Maresca, Krista Jansen, Frits Mastik,

Patrick WSerruys, Evelyn Regar, Erasmus MC - University Medical Center Rotterdam, Netherlands

WE-SS2.4: NEW DEVELOPMENTS IN FUNCTIONAL CARDIAC IMAGING 282

Jan D'hooge, Katholieke Universiteit Leuven, Belgium

TH-PS1: ULTRASOUNDIMAGING AND ANALYSIS

TH-PS1.1: ON ESTIMATING DE-SPECKLED AND SPECKLE COMPONENTS FROM 284

B-MODE ULTRASOUND IMAGES

Jose Seabra, Jodo Sanches, Instituto Superior Tecnico, Portugal

xvi

TH-PS1.2: RETRIEVAL AND CLASSIFICATION OF ULTRASOUND IMAGES OF 288

OVARIAN CYSTS COMBINING TEXTURE FEATURES AND HISTOGRAM

MOMENTS

Abu Sayeed Md. Sohail, Concordia University, Canada; Md. MahmudurRahman, National Institutes ofHealth,United States; Prabir Bhattacharya, University of Cincinnati, United States; Srinivasan Krishnamurthy, RoyalVictoria Hospital, Canada; Sudhir P. Mudur, Concordia University, Canada

TH-PS1.3: ON THE INFLUENCE OF INTERPOLATION ON PROBABILISTIC 292

MODELS FORULTRASONIC IMAGES

Gonzalo Vegas-Sdnchez-Ferrero, Diego Martin-Martinez, Santiago Aja-Ferndndez, Cesar Palencia,

Universidad de Valladolid, Spain

TH-PS1.4: QUANTITATIVE RESOLUTION OF ULTRASOUND IMAGES 296

Marie Ploquin, University of Tours, France; Denis Kouame, University of Toulouse, France

TH-PS1.5: ASSESSING TUMOURS VASCULARITY WITH 3D CONTRAST-ENHANCED 300

ULTRASOUND: A NEW SEMI-AUTOMATED SEGMENTATION FRAMEWORK

Anne Gasnier, Roberto Ardon, Cybele Ciofolo-Veit, Philips Medical Systems Research Paris, France; Edward

Leen, Imperial College London, United Kingdom; Jean-Michel Correas, Necker Hospital, France

TH-PS1.6: SEGMENTATION OF 2D STRESS ECHOCARDIOGRAPHY SEQUENCES 304

USING REST-BASED PATIENT-SPECIFIC PRIOR INFORMATION

Adeala Zabair, Alison Noble, University ofOxford, United Kingdom

TH-PS1.8: A COUPLED FILTERING METHOD TO SOLVE FEATURE-MOTION 312

DECORRELATION IN SPECKLE TRACKING

Tianzhu Liang, Weichuan Yu, The Hong Kong University ofScience and Technology, Hong Kong SAR of China

TH-PS1.9: MULTI-DOF PROBE TRAJECTORY RECONSTRUCTION WITHLOCAL 316

SENSORS FOR 2D-TO-3D ULTRASOUND

Philipp J. Stolka, Hyun-Jae Kang, Johns Hopkins University, United States; Michael Choti, EmadM, Boctor,

Johns Hopkins Medical Institutions, United States

TH-PS1.10: AUTOMATIC ACTIVE APPEARANCE MODEL SEGMENTATION OF 3D 320

ECHOCARDIOGRAMS

K. Y. Esther Leung, Erasmus MC - University Medical Center Rotterdam, Netherlands; Marijn Van Stralen,

University Medical Center Utrecht, Netherlands; Gerard Van Burken, Nico De Jong, Johan G. Bosch, Erasmus

MC - University Medical Center Rotterdam, Netherlands

TH-PS1.11: ULTRAFAST COMPOUND DOPPLER IMAGING: A NEW APPROACH OF 324

DOPPLER FLOW ANALYSIS

Gabriel Montaldo, Emilie Mace, Institute Langevin- Laboratoire Ondes et Acoustique, France; Ivan Cohen,

INSERMEMI 0224, France; Jeremy Berckoff, Supersonic Imagine, France; Mickael Tanter, Mathias Fink,

Institute Langevin- Laboratoire Ondes et Acoustique, France

xvii

TH-PS1.12: INCREASING TEMPORAL RESOLUTION OF 3D TRANSESOPHAGEAL 328

ULTRASOUND BY RIGID BODY REGISTRATION OF SEQUENTIAL,TEMPORALLY OFFSET SEQUENCES

Francisco J. Contijoch, Johns Hopkins University, United States; Laura Fernandez-de-Manuel, Universidad

Politecnica de Madrid, Spain; Tri Ngo, Johns Hopkins University, United States; Joshua Stearns, Kelly L.

Grogan, MaryBeth Brady, Johns Hopkins Hospital, United States; Philippe M. Burlina, Johns Hopkins Applied

Physics Laboratory, United States; Andres Santos, Universidad Politecnica de Madrid, Spain; David D. Yuh,

Johns Hopkins Hospital, United States; Daniel A. Herzka, Johns Hopkins University, United States; Maria J.

Ledesma-Carbayo, Universidad Politecnica de Madrid, Spain; Elliot R. McVeigh, Johns Hopkins University,United States

TH-PS1.13: ACCURATE SEGMENTATION OF ULTRASOUND IMAGES USING THE 332

MOTION CUE

Xiaowei Zhou, Tianzhu Liang, Weichuan Yu, The Hong Kong University ofScience and Technology, HongKong SAR of China

TH-PS2: IMAGE REGISTRATION

TH-PS2.1: LUNG CT REGISTRATION COMBININGINTENSITY, CURVES AND 340SURFACES

Vladlena Gorbunova, University of Copenhagen, Denmark; Stanley Durrleman, INRIA Sophia Antipolis,France; PechinLo, University of Copenhagen, Denmark; Xavier Pennec, INRIA Sophia Antipolis, France;Marleen de Bruijne, University of Copenhagen, Denmark

TH-PS2.2: A NOVEL MULTI-LAYER FRAMEWORK FOR NON-RIGID IMAGE 344REGISTRATION

Shu Liao, Albert C.S. Chung, The Hong Kong University ofScience and Technology, Hong Kong SAR of China

TH-PS2.3: VOXEL BASED NONRIGID IMAGE REGISTRATION USING LOCAL AND 348PARTIAL VOLUME SIMILARITY MEASURESDirk Loeckx, Frederik Maes, Dirk Vandermeulen, Paul Suetens, Katholieke Universiteit Leuven, Belgium

TH-PS2.4: DATA DRIVEN GROUPWISE REGISTRATION OF DIFFUSION WEIGHTED 352IMAGES

Andrew Melbourne, David Hawkes, David Atkinson, University College London, United Kingdom

TH-PS2.5: NONRIGID REGISTRATION WITH DIFFERENTIAL BIAS CORRECTION 356USING NORMALISED MUTUAL INFORMATION

MarcModat, Gerard R. Ridgway, David Hawkes, Nick Fox, Sebastien Ourselin, University College London,United Kingdom

TH-PS2.6: MODELING TOPOLOGICAL CHANGES IN DEFORMABLE REGISTRATION 360

Xiaoxing Li, Chris Wyatt, Virginia Tech, United States

xviii

TH-PS2.7: STATISTICALLY ASSISTED FLUID IMAGE REGISTRATION ALGORITHM - 364

SAFIRA

Caroline C. Brim, University ofCalifornia, Los Angeles, United States; Natasha Lepore, Children's Hospital,Los Angeles, United States; Xavier Pennec, Asclepios Project, France; Yi-Yu Chou, Agatha D. Lee, Marina

Barysheva, University of California, Los Angeles, United States; Greigl. deZubicaray, Katie L. McMahon, The

University of Queensland, Australia; Margaret J. Wright, Queensland Institute ofMedical Research, Australia;

Paul M. Thompson, University of California, Los Angeles, United States

TH-PS2.8: MULTI-MODAL NON-RIGID IMAGE REGISTRATION BASED ON 368

SIMILARITY AND DISSIMILARITY WITH THE PRIOR JOINT INTENSITY

DISTRIBUTIONS

Ronald W. K. So, Albert C.S. Chung, The Hong Kong University ofScience and Technology, Hong Kong SAR of

China

TH-PS2.9: MULTI-MODAL DIFFEOMORPHIC DEMONS REGISTRATION BASED ON 372

POINT-WISE MUTUAL INFORMATION

Huanxiang Lu, Mauricio Reyes, University ofBern, Switzerland; Amira Serifovic-Trbalic, University ofTuzla,Bosnia and Herzegovina; Stefan Weber, University ofBern, Switzerland; Yasuo Sakurai, Hitoshi Yamagata,TOSHIBA Medical Systems Corporation, Japan; Philippe C. Cattin, University ofBasel, Switzerland

TH-PS2.10: MULTI-ATTRIBUTE COMBINED MUTUAL INFORMATION (MACMI): AN 376

IMAGE REGISTRATION FRAMEWORK FOR LEVERAGING MULTIPLEDATA

CHANNELS

Jonathan Chappelow, Anant Madabhushi, Rutgers, The State University ofNew Jersey, United States

TH-PS2.11: BI-DIRECTIONAL LABELED POINT MATCHING 380

Roshni Bhagalia, James V. Miller, Arunabha Roy, GE Global Research, United States

TH-PS2.12: ACCOUNTING FOR CHANGING OVERLAP IN VARIATIONAL IMAGE 384

REGISTRATION

Nathan Cahill, Rochester Institute of Technology, United States; Alison Noble, University of Oxford, United

Kingdom; David Hawkes, University College London, United Kingdom

TH-PS2.13: SENSORLESS AND REAL-TIME REGISTRATION BETWEEN 2D 388

ULTRASOUND AND PREOPERATIVE IMAGES OF THE LIVER

Duhgoon Lee, Woo Hyun Nam, Korea Advanced Institute ofScience and Technology, Republic of Korea;

Donggyu Hyun, Medison Co., Ltd., Republic ofKorea; Jae Young Lee, Seoul National University Hospital,

Republic ofKorea; Jong Beom Ra, Korea Advanced Institute ofScience and Technology, Republic ofKorea

TH-PS2.14: NON-RIGID COREGISTRATION OF DIFFUSION KURTOSIS DATA 392

Jelle Veraart, University ofAntwerp, Belgium; Wim Van Hecke, Antwerp University Hospital, Belgium; Ines

Blockx, Annemie Van Der Linden, Marleen Verhoye, Jan Sijbers, University ofAntwerp, Belgium

TH-PS2.15: GROUPWISE REGISTRATION FROM EXEMPLAR TO GROUP MEAN: 396

EXTENDING HAMMER TO GROUPWISE REGISTRATION

Guorong Wu, Pew-Thian Yap, Qian Wang, Dinggang Shen, University ofNorth Carolina at Chapel Hill, United

States

TH-PS2.16: DETECTING MUTUALLY-SALIENT LANDMARK PAIRS WITH MRF 400

REGULARIZATION

Yangming Ou, University ofPennsylvania, United States; Ahmed Besbes, Ecole Centrale de Paris - GALEN

Group INRIA Saclay, France; Michel Bilello, Mohamed Mansour, Christos Davatzikos, University of

Pennsylvania, United States; Nikos Paragios, Ecole Centrale de Paris - GALEN Group INRIA Saclay, France

xix

TH-PS3: SHAPE MODELING AND ANALYSIS

TH-PS3.1: JOINT ANALYSIS OF CORTICAL FOLDING PATTERN, THICKNESS AND 404

FIBER DENSITY USING STRUCTURAL AND DTI DATA

Yixuan Yuan, Lei Guo, Gang Li, Tuo Zhang, Xintao Hu, Northwestern Polytechnical University, China;

Tianming Liu, The University ofGeorgia, United States

TH-PS3.2: PREDICTION OF SCOLIOSIS CURVE TYPE BASED ON THEANALYSIS 408

OF TRUNK SURFACE TOPOGRAPHY

Lama Seoud, Mathias Adankon, Ecole Polytechnique de Montreal, Canada; Hubert Labelle, Sainte-Justine

Hospital Research Center, Canada; Jean Dansereau, Farida Cheriet, Ecole Polytechnique de Montreal,

Canada

TH-PS3.3: EVALUATION OF SAGITTAL VERTEBRAL ROTATION IN CT IMAGES BY 412

MANUAL AND AUTOMATED METHODS

Tomaz Vrtovec, Franjo Pernus, Bostjan Likar, University ofLjubljana, Slovenia

TH-PS3.4: AUTOMATED QUANTIFICATION AND ANALYSIS OF MANDD3ULAR 416

ASYMMETRY

TronA. Darvann, Nuno V. Hermann, PerLarsen, University of Copenhagen, Denmark; Hildur Olafsdottir,

Technical University ofDenmark, Denmark; Izabella V. Hansen, University of Copenhagen, Denmark; Hanne

D. Hove, Copenhagen University Hospital Rigshospitalet, Denmark; LeifChristensen, Arhus University

Hospital, Denmark; Daniel Rueckert, Imperial College London, United Kingdom; Sven Kreiborg, University of

Copenhagen, Denmark

TH-PS3.5: AUTOMATIC INFERIOR VENA CAVA SEGMENTATIONIN 420

CONTRAST-ENHANCED CT VOLUMES

Thierry Lefevre, Benoit Mory, Roberto Ardon, Javier Sanchez-Castro, Philips Healthcare, France; Anthony

Yezzi, Georgia Institute ofTechnology, United States

TH-PS3.6: SHAPE-BASED SEMI-AUTOMATIC HIPPOCAMPAL SUBFIELD 424

SEGMENTATION WITHLEARNING-BASED BIAS REMOVAL

Hongzhi Wang, Sandhitsu Das, John Pluta, Caryne Craige, Murat Altinay, University ofPennsylvania, United

States; Michael Weiner, Susanne Mueller, Department of Veterans Affairs Medical Center, United States; Paul

Yushkevich, University ofPennsylvania, United States

TH-PS3.7: COMBINATION OF SHAPE-CONSTRAINED AND INFLATION DEFORMABLE 428

MODELS WITH APPLICATION TO THE SEGMENTATION OF THE LEFT ATRIAL

APPENDAGE

Pol Grasland-Mongrain, Ecole Normale Superieure de Cachan, France; Jochen Peters, Olivier Ecabert,

Philips Research Europe - Aachen, Germany

TH-PS3.8: AUTOMATIC SEGMENTATION OF BONES AND INTER-IMAGE 432

ANATOMICAL CORRESPONDENCE BY VOLUMETRIC STATISTICAL

MODELLING OF KNEE MRI

Tomos Williams, University ofManchester, United Kingdom; Graham Vincent, Mike Bowes, Imorphics Ltd,United Kingdom; Timothy Cootes, Sharon Balamoody, Charles Hutchinson, University ofManchester, United

Kingdom; John Waterton, AstraZeneca, United Kingdom; Chris Taylor, University ofManchester, United

Kingdom

XX

TH-PS3.9: TETRAHEDRAL MESH GENERATION FOR MEDICAL IMAGES WITH 436

MULTIPLE REGIONS USING ACTIVE SURFACES

Carl Lederman, AnandA. Joshi, John Darrell Van Horn, Ivo Dinov, Luminita Vese, Arthur Toga, University ofCalifornia, Los Angeles, United States

TH-PS3.10: IMPROVING THE DETECTION OF OSTEOPOROSIS FROM DENTAL 440

RADIOGRAPHS USING ACTIVE APPEARANCE MODELS

Martin Roberts, James Graham, Hugh Devlin, University ofManchester, United Kingdom

TH-PS3.11: 3D LEVEL SET ESOPHAGUS SEGMENTATION IN THORACIC CT IMAGES 444

USING SPATIAL, APPEARANCE AND SHAPE MODELS

Sila Kurugol, Jennifer G. Dy, Northeastern University, United States; Gregory C. Sharp, Massachusetts

General Hospital and Han'ard Medical School, United States; Dana H. Brooks, Northeastern University,United States

TH-PS3.12: A METHOD FOR QUANTITATIVE EVALUATION OF STATISTICAL SHAPE 448

MODELS USING MORPHOMETRY

Sebastian T. Gollmer, Thorsten M. Buzug, University of Liibeck, Germany

TH-PS3.13: PARAMETRIC REGRESSION OF 3D MEDICAL IMAGES THROUGH THE 452

EXPLORATION OF NON-PARAMETRIC REGRESSION MODELS

Christof Seller, University ofBern, Switzerland; Xavier Pennec, INRIA Sophia, France; Mauricio Reyes,University ofBern, Switzerland

TH-PS3.14: 3D RECONSTRUCTION OF BOTH SHAPE AND BONE MINERAL 456

DENSITY DISTRIBUTION OF THEFEMUR FROM DXA IMAGES

Ludovic Humbert, Tristan Whitmarsh, Mathieu De Craene, Universitat Pompeu Fabra, Spain; Luis Migueldel Rio Barquero, CETIR Centre Medic, Spain; Karl Fritscher, Rainer Schubert, The Health and Life Sciences

University (UMIT), Austria; Felix Eckstein, PMU (Paracelsus Medical University), Austria; Thomas Link,

University of California, San Francisco, United States; Alejandro Frangi, Universitat Pompeu Fabra, Spain

TH-PS4: CARDIAC IMAGING AND ANALYSIS

TH-PS4.1: FULLY 5D RECONSTRUCTION OF GATED DYNAMIC CARDIAC SPECT 460

IMAGES USING TEMPORAL B-SPLINES

Xiaofeng Niu, Yongyi Yang, Illinois Institute of Technology, United States; Mingwu Jin, University of ColoradoDenver, United States

TH-PS4.2: AN MRI-BASED CARDIAC ELECTROANATOMICAL MAPPING SYSTEM WITH 464

SCATTERED DATA INTERPOLATION ALGORITHM

Gang Gao, Phani Chinchapatnam, Matthew Wright, Aruna Arujuna, Matthew Ginks, King's College London,

United Kingdom; Aldo Rinaldi, Guy's & St. Thomas' Hospitals NHS Foundation Trust, United Kingdom;Kawal Rhode, King's College London, United Kingdom

TH-PS4.3: IDENTIFICATION OF MYOCARDIAL INFARCTION USING 468

THREE-DIMENSIONAL STRAIN TENSOR FRACTIONAL ANISOTROPY

Sahar Soleimanifard, Khaled Z. Abd-Ehnoniem, Harsh K. Agarwal, Miguel S. Tomas, Tetsuo Sasano, EvertjanVonken, Amr Youssef, M. Roselle Abraham, Theodore P. Abraham, Jeny L. Prince, Johns Hopkins University,United States

xxi

TH-PS4.4: AUTOMATIC SEGMENTATION OF PATHOLOGICAL TISSUES IN CARDIAC 472

MRI

Khaoula Elagouni, Cybele Ciofolo-Veit, BenoitMory, Philips Healthcare France, France

TH-PS4.5: BILINEAR POINT DISTRIBUTION MODELS FOR HEART MOTION 476

ANALYSIS

Rosa M. Figueras i Ventura, Come Hoogendoom, Federico Sukno, Alejandro Frangi, C1STIB-UPF, Spain

TH-PS4.6: CARDIAC LEFT ATRIUM CT IMAGE SEGMENTATION FOR ABLATION 480

GUIDANCE

Marc M.J. Koppert, Eindhoven University of Technology, Netherlands; Peter M.J. Rongen, Philips Healthcare,

Netherlands; Mathias Prokop, University Medical Center Utrecht, Netherlands; Bart M. ter Haar Romeny,Hans C. vanAssen, Eindhoven University ofTechnology, Netherlands

TH-PS4.7: CARDIAC SEGMENTATION IN MR CINE DATA USING INVERSE 484

CONSISTENT DEFORMABLE REGISTRATION

Marie-Pierre Jolly, Christoph Guetter, Jens Guehring, Siemens Corporate Research, United States

TH-PS4.8: PARTICLE FILTERING METHODS FOR MOTION ANALYSIS IN TAGGED 488

MRI

Ihor Smal, Wiro Niessen, Erik Meijering, Erasmus MC - University Medical Center Rotterdam, Netherlands

TH-PS4.9: SPATIO-TEMPORAL SEGMENTATION OF THE HEART IN 4D MRI IMAGES 492

USING GRAPH CUTS WITH MOTION CUES

Herve Lombaert, Farida Cheriet, Ecole Polytechnique de Montreal, Canada

TH-PS4.10: STATIC AND DYNAMIC CARDIAC MODELLING: INITIAL STRIDES AND 496

RESULTS TOWARDS A QUANTITATIVELY ACCURATE MECHANICAL HEART

MODEL

Christakis Constantinides, Nikolas Aristokleous, University of Cyprus, Cyprus; G. A. Johnson, Duke University,United States; Dimitris Perperidis, University of Cyprus, Greece

TH-PS4.11: AUTOMATED EVALUATION OF LEFT VENTRICULAR DIASTOLIC 500

FUNCTION USING VELOCITY-ENCODED MAGNETIC RESONANCE IMAGING:

CONVENTIONAL AND NEW PARAMETERS

Emilie Bollache, INSERM U678, France; Stephanie Clement-Guinaudeau, Ludivine Perdrix, MagalieLadouceur, European Hospital Georges Pompidou, France; Muriel Lefort, Alain De Cesare, Alain Herment,INSERM U678, France; Benott Diebold, Elie Mousseaux, European Hospital Georges Pompidou, France;Nadjia Kachenoura, INSERM U678, France

TH-PS4.12: PATIENT-SPECIFIC MODELING OF LEFT HEART ANATOMY, DYNAMICS 504AND HEMODYNAMICS FROM HIGH RESOLUTION 4D CT

Viorel Mihalef Razvan Ionasec, Yang Wang, Yefeng Zheng, Bogdan Georgescu, Dorin Comaniciu, Siemens

Corporate Research, United States

TH-PS4.13: MOTION-BASED, MULTI-MODALITY IMAGE REGISTRATION FOR 508

CARDIAC IMAGING

Alan Cebula, David Gilland, Jason Parker, Yunmei Chen, University ofFlorida, United States

TH-PS4.14: REGULARIZED MULTILEVEL B-SPLINE REGISTRATION: APPLICATION 512

TO CARDIAC MOTION ESTIMATION

Marco Mora, Juan Andrade, Catholic University ofMaule, Chile; Clovis Tauber, UMRS INSERM U930CNRS FRE2448 - University of Tours, France

xxii

TH-PS4.15: PHASE-BASED NON-RIGID REGISTRATION OF MYOCARDIAL 516

PERFUSION MRI IMAGE SEQUENCESLennart Tautz, Anja Hennemuth, Fraunhofer MEVIS, Germany; Mats Andersson, Linkoping University,Sweden; Achim Seeger, Eberhard Karls University Tuebingen, Germany; Hans Knutsson, Linkoping University,Sweden; Ola Friman, Fraunhofer MEVIS, Germany

TH-PS4.16: MOTION-COMPENSATED RECONSTRUCTION OF GATED CARDIAC 520

SPECT IMAGES USING A DEFORMABLE MESH MODEL

Thibault Marin, Miles N. Wernick, Yongyi Yang, Jovan G. Brankov, Illinois Institute of Technology, UnitedStates

TH-OS1: IMAGE REGISTRATION I

TH-OSl.l: A KERNEL-BASED GRAPHICAL MODEL FOR DIFFUSION TENSOR 524

REGISTRATION

Aristeidis Sotiras, Radhouene Neji, Ecole Centrale Paris /INRIA Saclay, France; Jean-Francois Deux, Centre

Hospitaller Universitaire Henri Mondor, France; Nikos Komodakis, University of Crete, Greece; Gilles Fleury,SUPELEC, France; Nikos Paragios, Ecole Centrale Paris / INRIA Saclay, France

TH-OS1.2: PIECEWISE SMOOTH AFFINE REGISTRATION OF POINT-SETS WITH 528

APPLICATION TO DT-MRI BRAIN FIBER-DATA

Ran Shadmi, Amaldo Mayer, Nir Sochen, Hayit Greenspan, Tel-Aviv University, Israel

TH-OS1.3: PHYSICALLY-BASED DEFORMABLE IMAGE REGISTRATION WITH 532MATERIAL PROPERTY AND BOUNDARY CONDITION ESTIMATION

Huai-Ping Lee, Mark Foskey, Marc Niethammer, Ming Lin, University ofNorth Carolina at Chapel Hill,United States

TH-OS1.4: ACCURATE REGISTRATION OF DYNAMIC CONTRAST-ENHANCED 536

BREAST MRIMAGES WITH ROBUST ESTIMATION AND LINEAR

PROGRAMMING

Yuanjie Zheng, University of Pennsylvania, United States; Andrew Maidment, Hospital ofthe University ofPennsylvania, United States; James Gee, University ofPennsylvania, United States

TH-OS2: BIOLOGICAL IMAGE ANALYSIS

TH-OS2.1: JOINT TRACKING AND LOCOMOTION STATE RECOGNITION OF 540

C.ELEGANS FROM TIME-LAPSE IMAGE SEQUENCESYu Wang, Badrinath Roysam, Rensselaer Polytechnic Institute, United States

TH-OS2.2: MULTI-TARGET TRACKING OF PACKED YEAST CELLS 544

Ricard Delgado-Gonzalo, Nicolas Denervaud, Sebastian Maerkl, Michael Unser, Ecole Polytechnique Federalede Lausanne (EPFL), Switzerland

TH-OS2.3: TREE2TREE: NEURON SEGMENTATION FOR GENERATION OF 548

NEURONAL MORPHOLOGY

Saurav Basu, AllaAksel, Barry Condron, Scott T. Acton, University of Virginia, United States

xxiii

TH-OS2.4: RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE 552

MODELS

Carolina Wdhlby, Broad Institute of MIT and Harvard, United States; Tammy Riklin-Raviv, Massachusetts

Institute of Technology, United States; Vebjom Ljosa, Broad Institute ofMIT and Harvard, United States;

Annie L Conery, Massachusetts General Hospital, United States; Polina Golland, Massachusetts Institute of

Technology, United States; Frederick M. Ausubel, Massachusetts General Hospital, United States; Anne E.

Carpenter, Broad Institute ofMIT and Harvard, United States

TH-OS3: LUNG IMAGE SEGMENTATION

TH-OS3.1: INTERACTIVELY LEARNING A PATIENT SPECIFIC K-NEAREST 556

NEIGHBOR CLASSIFIER BASED ON CONFIDENCE WEIGHTED SAMPLES

Eva Marjolein van Rikxoort, Jonathan Goldin, University of California, Los Angeles, United States; Bram van

Ginneken, University Medical Center Utrecht, Netherlands; Maya Galperin-Aizenberg, Chiayi Ni, Matthew

Brown, University of California, Los Angeles, United States

TH-OS3.2: AUTOMATIC SEGMENTATION OF LUNG LOBES IN CT IMAGES BASED 560

ON FISSURES, VESSELS, AND BRONCHI

Bianca Lassen, Jan-Martin Kuhnigk, Ola Friman, Stefan Krass, Heinz-Otto Peitgen, Fraunhofer MEVIS,Germany

TH-OS3.3: INTERACTIVE LUNG SEGMENTATION IN CT SCANS WITH SEVERE 564

ABNORMALITIES

Thessa Kockelkorn, University Medical Center Utrecht, Netherlands; Eva Marjolein van Rikxoort, UniversityofCalifornia, Los Angeles, United States; Jan Grutters, St Antonius Ziekenhuis Nieuwegein, Netherlands; Bramvan Ginneken, Radboud University Nijmegen Medical Centre, Netherlands

TH-OS3.4: AUTOMATIC LEAKAGE DETECTION AND RECOVERY FOR AIRWAY TREE 568

EXTRACTION IN CHEST CT IMAGES

Mario Ceresa, Xabier Artaechevarria, Arrate Munoz-Barrutia, Carlos Ortiz-de-Solorzano, CIMA, Spain

TH-SS1: HIGH-FIELD CLINICAL MRI

TH-SS1.1: IN VIVO MRI OF THE HUMAN TORSO AT 7 TESLA USING 572

MULTI-CHANNEL TRANSMIT

Mark Ladd, Lale Umutlu, Stefan Maderwald, Sonja Kinner, Stephan Orzada, Kai Nassenstein, Irina Brote,Harald Quick, Lena Schaefer, Susanne Ladd, Gerald Antoch, Oliver Krajf, Andreas Bitz, Thomas Lauenstein,University Duisburg-Essen, Germany

TH-SS1.2: HIGH FIELD CLINICAL MRI NEUROIMAGING 573Mark van Buchem, Jeroen van der Grond, Maarten Versluis, Thijs van Osch, Hermien Kan, Wouter Teeuwisse,Andrew Webb, Leiden University Medical Center, Netherlands

TH-SS1.3: CHALLENGES FOR HIGH FIELD CLINICAL MRI 575

Andrew Webb, Leiden University Medical Center, Netherlands

TH-SS1.4: PROTOCOL DEVELOPMENT FOR HIGH FIELD CLINICAL MRI 579

Peter Luijten, University Medical Center Utrecht, Netherlands

xxiv

TH-OS4: CELLULAR AND MOLECULARIMAGE ANALYSIS I

TH-OS4.1: MITOSIS SEQUENCEDETECTION USING HIDDEN CONDITIONAL 580

RANDOM FIELDS

AnanLiu, Carnegie Mellon University, United States / Institute of Computing Technology, Chinese Academy

ofSciences, China / Tianjin University, China; Rang Li, Microsoft Corporation, United States; Takeo Kanade,

Carnegie Mellon University, United States

TH-OS4.2: ENHANCED DETECTION OF CELL PATHS IN SPATIOTEMPORAL PLOTS 584

FOR NONINVASIVE MICROSCOPY OF THE HUMAN RETINA

Johnny Tarn, University of California, Berkeley, and University of California, San Francisco, United States;

Austin Roorda, University of California, Berkeley, United States

TH-OS4.3: ANISOTROPIC PLATE DIFFUSION FILTERING FOR DETECTION OF 588

CELL MEMBRANES IN 3D MICROSCOPY IMAGES

Kishore Mosaliganti, Harvard Medical School, United States; Firdaus Janoos, The Ohio State University,United States; Arnaud Gelas, Ramil Noche, Nik Obholzer, Harvard Medical School, .United States; Raghu

Machiraju, The Ohio State University, United States; Sean Megason, Harvard Medical School, United States

TH-OS4.4: A BOTTOM-UP AND TOP-DOWN MODEL FOR CELL SEGMENTATION 592

USING MULTISPECTRAL DATA

Xuqing Wu, Shishir Shah, University ofHouston, United States

TH-OS5: TOMOGRAPHIC RECONSTRUCTION

TH-OS5.1: OPTIMIZATION TRANSFER APPROACH TO JOINT REGISTRATION / 596

RECONSTRUCTION FOR MOTION-COMPENSATED IMAGE RECONSTRUCTION

Jeffrey Fessler, University ofMichigan, United States

TH-OS5.2: ABOX SPLINE CALCULUS FOR COMPUTED TOMOGRAPHY 600

Alireza Entezari, University of Florida, United States; Michael Unser, Ecole Polytechnique Federale de

Lausanne (EPFL), Switzerland

TH-OS5.3: ITERATIVE REGION OF INTEREST RECONSTRUCTION IN EMISSION 604

TOMOGRAPHY

Jun Ma, Macquarie University, Australia

TH-OS5.4: A WAVELET ALGORITHM FOR ZOOM-IN TOMOGRAPHY 608

Max Longer, Franqoise Peyrin, European Synchrotron Radiation Facility / INSA Lyon, France

TH-OS6: TRACKING AND MOTION ANALYSIS

TH-OS6.1: USING NEEDLE DETECTION AND TRACKING FOR MOTION 612

COMPENSATION INABDOMINAL INTERVENTIONS

Peng Wang, Pfister Marcus, Terrence Chen, Dorin Comaniciu, Siemens, United States

TH-OS6.2: SHAPE AND MOTION ANALYSIS OF LEFT VENTRICLE 616DYSSYNCHRONY FROM REAL-TIME 3D ECHOCARDIOGRAPHY

Honghai Zhang, Ademola Abiose, Dwayne Campbell, Milan Sonka, James Martins, Andreas Wahle, UniversityofIowa, United States

XXV

TH-OS6.3: REAL TIME TRACKING OF 3D ORGAN SURFACES USING SINGLE MR 620

IMAGE AND LIMITED OPTICAL VIEWING

Dan Wang, Ahmed Tewfik, University ofMinnesota, United States

TH-OS6.4: NEEDLE TRACKING THROUGH HIGHER-ORDER MRF OPTIMIZATION 624

T. Hauke Heibel, Ben Glocker, Nassir Navab, Technische Universitdt Munchen, Germany; Nikos Paragios,

Ecole Centrale Paris, France

TH-SS2: DIFFUSION AND FUNCTIONAL MRI

TH-SS2.1: THEORY AND APPLICATIONS OF DIFFUSION MRI 628

Alexander Leemans, Image Sciences Institute, University Medical Center Utrecht, Netherlands

TH-SS2.2: TOWARDS AN INTEGRATED ANALYSIS OF ANATOMICAL AND FUNCTIONAL ....632

CONNECTIVITY

Marc Tittgemeyer, Max-Planck-Institute for Neurological Research, Germany

TH-SS2.3: CHALLENGES IN MR IMAGE ACQUISITION AND ANALYSIS FOR 633

PROBING THE HUMAN CONNECTOME IN VIVO

Anastasia Yendiki, Harvard Medical School / Massachusetts General Hospital, United States

TH-SS2.4: CONNECTIVITY CONCEPTS IN DIFFUSION AND FUNCTIONAL MRI 635

Carl-Fredrik Westin, Harvard Medical School and Brigham and Women's Hospital, United States

TH-OS10: CANCER IMAGING AND ANALYSIS

TH-OS10.1: COMPUTER-AIDED GLEASON GRADING OF PROSTATE CANCER 636

HISTOPATHOLOGICAL IMAGES USING TEXTON FORESTS

Parmeshwar Khurd, Claus Bahlmann, Peter Maday, Ali Kamen, Siemens Corporate Research, United States;

Summer Gibbs-Strauss, Elizabeth M. Genega, John V. Frangioni, Beth Israel Deaconess Medical Center,

United States

TH-OS10.2: MR PRIORBASED AUTOMATIC SEGMENTATION OF THE PROSTATE IN 640

TRUS IMAGES FOR MR/TRUS DATA FUSION

Sebastien Martin, Michael Baumann, Universite J.Fourier, France; Vincent Daanen, KOELIS, France;

Jocelyne Troccaz, Universite J.Fourier, France

TH-OS10.3: IMPROVED PROSTATE CANCER LOCALIZATION WITH SPATIALLY 644

REGULARIZED DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE

IMAGING

Liu Lukai, Illinois Institute of Technology, United States; MasoomA. Haider, Mount Sinai Hospital, Canada;

Deanne L. Langer, University of Toronto, Canada; Imam Samil Yetik, Illinois Institute of Technology, United

States

TH-OS10.4: SEMI-SUPERVISED PROSTATE CANCER SEGMENTATION WITH 648

MULTISPECTRAL MRI

YusufArtan, Illinois Institute of Technology, United States; Masoom A. Haider, Mount Sinai Hospital,

University Health Network, Canada; Deanne L. Langer, University of Toronto, Canada; Imam Samil Yetik,

Illinois Institute of Technology, United States

xxvi

TH-OS7: FUNCTIONAL MRI AND ANALYSIS

TH-OS7.1: CONDITIONAL INTEGRATION AS A WAY OF MEASURING MEDIATED 652

INTERACTIONS BETWEEN LARGE-SCALE BRAIN NETWORKS IN FUNCTIONAL

MRI

David Coynel, Guillaume Marrelec, Vincent Perlbarg, Inserm and UPMC Univ Paris 06, France; Julien

Doyon, University ofMontreal, Canada; Habib Benali, Inserm and UPMC Univ Paris 06, France

TH-OS7.2: CORTICAL SURFACE BASED IDENTIFICATION OF BRAIN NETWORKS 656

USING HIGH SPATIAL RESOLUTION RESTING STATE FMRI DATA

Kaiming Li, Northwestern Polytechnical University, China / University of Georgia, United States; Lei Guo,

Gang Li, Jingxin Nie, Northwestern Polytechnical University, China; Carlos Faraco, Qun Zhao, Stephen

Miller, Tianming Liu, University of Georgia, United States

TH-OS7.3: STATISTICAL PARAMETRIC MAPPING OF FMRI DATA USING SPARSE 660

DICTIONARY LEARNING

Kangjoo Lee, Jong Chul Ye, Korea Advanced Institute ofScience and Technology, Republic ofKorea

TH-OS7.4: HIGH-ORDER CONCEPT DISCOVERY IN FUNCTIONAL BRAIN IMAGING 664

Michael Barnathan, Vasileios Megalooikonomou, Temple University, United States; Christos Faloutsos,

Carnegie Mellon University, United States; Feroze Mohamed, Scott Faro, Temple University School of

Medicine, United States

TH-OS8: VASCULAR IMAGE SEGMENTATION

TH-OS8.1: AUTOMATIC SEGMENTATION OF PULMONARY VASCULATURE IN 668

THORACIC CT SCANS WITH LOCAL THRESHOLDING AND AIRWAY WALL

REMOVAL

Evelien van Dongen, Image Sciences Institute, University Medical Center Utrecht, Netherlands; Brain van

Ginneken, Radboud University Nijmegen Medical Centre, Netherlands

TH-OS8.2: AN ITERATIVE MODEL-CONSTRAINED GRAPH-CUT ALGORITHM FOR 672

ABDOMINAL AORTIC ANEURYSM THROMBUS SEGMENTATION

Moti Freiman, The Hebrew University ofJerusalem, Israel; Steven Esses, Hadassah Hebrew UniversityMedical Center, Israel; Leo Joskowicz, The Hebrew University ofJerusalem, Israel; Jacob Sosna, Hadassah

Hebrew University Medical Center, Israel

TH-OS8.3: VESSEL SEGMENTATION IN EYE FUNDUS IMAGES USING ENSEMBLE 676

LEARNING AND CURVE FITTING

Elco Oost, Yuki Akatsuka, Akinobu Shimizu, Hidefumi Kobatake, Tokyo University ofAgriculture and

Technology, Japan; Daisuke Furukawa, Akihiro Katayama, Canon, Inc., Japan

TH-OS8.4: VESSEL TREE EXTRACTION USING LOCALLY OPTIMAL PATHS 680

Pechin Lo, Marleen de Bruijne, University of Copenhagen, Denmark; Bram van Ginneken, University Medical

Center Utrecht, Netherlands

TH-OS9: OPTICAL IMAGING

TH-OS9.1: COMPRESSED SENSING FOR DIGITAL HOLOGRAPHIC MICROSCOPY 684

Marcio de Moraes Marim, Institut Pasteur, France; Michael Atlan, ESPCI ParisTech, France; Elsa D.

Angelini, Telecom ParisTech, France; Jean-Christophe Olivo-Marin, Institut Pasteur, France

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TH-OS9.2: BIOLUMINESCENCE ENHANCEMENT THROUGH FUSION OF OPTICAL 688

IMAGING AND CINEMATIC VIDEO FLOW

Mickael Savinaud, Ecole Centrale Paris /INRIA GALEN / Biospace Lab, France; Aristeidis Sotiras, Ecole

Centrale Paris/INRIA GALEN, France; Serge Maitrejean, Biospace Lab, France; Nikos Paragios, Ecole

Centrale Paris/INRIA GALEN, France

TH-OS9.3: APRIORI GUIDED RECONSTRUCTION FOR FDOT USING MIXED 692

NORMS

Jean-Charles Baritaux, Michael Unser, Swiss institute of technology ofLausanne, Switzerland

TH-OS9.4: FAST LOCALIZE THE BIOLUMINESCENT SOURCE VIA GRAPH CUTS 696

Kai Liu, Jie Tian, Shouping Zhu, Chenghu Qin, Xing Zhang, Dong Han, Institute ofAutomation, Chinese

Academy of Sciences, China

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