Supplementary Figure 1. Forest plot showing the proportion...

Supplementary Figure 1. Forest plot showing the proportion of ascites in patients with tusanqi-

related SOS.

Supplementary Figure 2. Forest plot showing the proportion of hepatomegaly in patients with

tusanqi-related SOS.

Supplementary Figure 3. Forest plot showing the proportion of jaundice in patients with tusanqi-

related SOS.

Supplementary Figure 4. Forest plot showing the proportion of plueral effusion in patients with


Supplementary Figure 5. Forest plot showing the proportion of lower limbs edema in patients with


Supplementary Figure 6. Forest plot showing the proportion of splenomegaly in patients with


Supplementary Figure 7. Forest plot showing the proportion of upper gastrointestinal bleeding in

patients with tusanqi-related SOS.

Supplementary Figure 8. Forest plot showing the proportion of gastroesophageal varices in

patients with tusanqi-related SOS.

Supplementary Figure 9. Forest plot showing the proportion of hepatic encephalopathy in patients

with tusanqi-related SOS.

Supplementary Table 1. Exclusion of relevant studies with overlapping data

Type of papers

AffiliationsFirst author

JournalsExcluded or included

Zhang Junxia

Yao Wu Bu Liang Fan Ying Za Zhi 2009;11(6);425-426 ExcludedBeijing Ditan Hospital Affiliated to Capital Medical University Cheng

DanyingZhong Guo Gan Zang Bing Za Zhi 2012;4(4);26-28 Included

Wu Xiaowei

Shi Yong Gan Zang Bing Za Zhi 2010;13(2);139-140 ExcludedNanjing General Hospital of Nanjing Military Command Hou

YuHu Li Yan Jiu 2011;25(1);178-179 Included

Duan Hongguang

Ren Min Jun Yi 2011;54(3);215 ExcludedPLA 155 Central Hospital, Kaifeng, Henan Peng

PeiliGong Neng Yu Fen Zi Yi Xue Ying Xiang Xue 2012;1(4);297-298 Included

Gao Xinsheng

Zhong Guo Zhong Xi Yi Jie He Xiao Hua Za Zhi 2006;14(6);416-417

Excluded

Case report (4)

Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Tecnology

Huang Huanjun

Lin Chuang Xiao Hua Bing Za Zhi 2008;20(1);26-28.32 Included

Zhong Jianfeng

Xian Dai Shi Yong Yi Xue 2010;22(7);787-788 ExcludedHuzhou Central Hospital

Yao Lidi

Xian Dai Shi Yong Yi Xue 2012;24(8);935-936 Included

Chen Huazhong

Zhong Hua Ling Chuang Gan Ran Bing Za Zhi 2010;3(2);76-79 Excluded

Geng Caizheng

Zhong Hua Fang She Xue Za Zhi 2009;43(3);312-314 ExcludedTaizhou Hospital Affiliated to Wenzhou Medical College

Chen Huazhong

Lin Chuang Gan Dan Bing Za Zhi 2012;28(5);376-379 Included

Fang Guoping

Zhong Hua Chuan Ran Bing Za Zhi 2007;25(6);373-374 Excluded

Yang Miaomiao

Chang Zhou Shi Yong Yi Xue 2010;26(5);292-293 Excluded

Zhang Huifen

Xian Dai Zhong Xi Yi Jie He Za Zhi 2012;21(7);767-768 Excluded

Zhang Luxi

Jie Ru Fang She Xue Za Zhi 2012;21(12);987-990 Excluded

Zhang Weimin

Su Zhou Da Xue Xue Bao (Yi Xue Ban) 2009;29(6);1196-1198 Excluded

The Third People's Hospital of Changzhou

Yao Lingdi

Xian Dai Zhong Xi Yi Jie He Za Zhi 2014;23(30);3371-3372 Included

Zhu Xiuqin

Zhong Hua Xian Dai Hu Li Za Zhi 2008;14(15);1702-1703 ExcludedTongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology

Zhu Xiuqin

Hu Li Yan Jiu 2011;25(5);1272-1273 Included

Ma Lixin

Lin Chuang Yi Xue 2006;26(5);86 Excluded

Zhang Guohua

Zhong Hua Fang She Xue Za Zhi 2006;40(3);250-254 Excluded

Ma Xinguang

Zhe Jiang Lin Chuang Yi Xue 2008;10(5);593-594 Included

Xianju County People's Hospital

Xu Haibo Zhong Guo Xiang Cun Yi Yao 2010;17(9);45 Included

Huang Xiaoming

Zhong Xi Yi Jie He Gan Bing Za Zhi 2011;21(5);280-281+323 Excluded

Tang Wenjuan

Fang She Xue Shi Jian 2012;27(11);1235-1237 Excluded

Xiehe Hospital Affiliated to Tongji Medical college Huazhong University of Science and Technology Ye

Tianhe Hua Dong Ke Ji Da Xue Shuo Shi Xue Wei Lun Wen (2013) Included

Wu Xinjun

Zhong Hua Gan Zang Bing Za Zhi 2013;21(8);635-636 Excluded

Case series type I (17)

Xinchang County People's Hospital

Yu Mengyong

Zhong Guo Xiang Cun Yi Yao 2012;19(16);62-63 Excluded

Yu Zidong

Qing Zhu Zhong Guo Chao Sheng Zhen Duan 50 Nian Ji Di Shi Jie Quan Guo Chao Sheng Yi Xue Xue Shu Hui Yi 2008;260-261

Excluded

Zhang Manping

Zhe Jiang Chuang Shang Wai Ke 2009;14(1);90 Excluded

Zhang Kui

Zhe Jiang Zhong Xi Yi Jie He Za Zhi 2013;23(8);647-649 Included

Chen Shuang

Zhong Guo Yi Xue Ying Xiang Xue Za Zhi 2010;18(2);154-156 ExcludedGeneral Hospital of Armed Police Forces Zhang

WeiZhong Guo Xian Dai Pu Tong Wai Ke Jin Zhan 2014;17(3);239-241

Included

Chai Guojun

Wu Jing Yi Xue 2007;18(11);828-830 ExcludedPeoples Liberation Army General Hospital Ding

PengpengJie Fang Jun Yi Xue Yuan Xue Bao 2013;34(1);34-36+52 Included

Zhang Yanting

Zhong Hua Yi Xue Hui Di Shi Liu Ci Quan Guo Bing Du Xing Gan Yan Ji Gan Bing Xue Shu Hui Yi 2013;489-490

ExcludedThe First Affiliated Hospital of Nanjing Medical University Zhang

YantingLin Chuang Gan Dan Bing Za Zhi 2013;29(12);936-939 Included

Chen Hongtan

Zhe Jiang Da Xue Shuo Shi Xue Wei Lun Wen (2006) Excluded

Chen Yipeng

Zhong Hua Xiao Hua Za Zhi 2006;26(4);224-226 Excluded

Huang Zhiliang

2006 Nian Zhe Jiang Sheng Chao Sheng Yi Xue Xue Shu Nian Hui 2006;60-61

Excluded

Tao Jingjing

Zhe Jiang Da Xue Shuo Shi Xue Wei Lun Wen (2011) Excluded

Ying Shihong

Lin Chuang Fang She Xue Za Zhi 2011;30(9);1302-1305 Excluded

Jiang Tian'an

Zhong Guo Chao Sheng Yi Xue Za Zhi 2008;24(10);951-955 Included

The First Affiliated Hospital of Zhejiang University Medical College

Zhu Wanlin

Zhong Hua Xiao Hua Za Zhi 2012;32(9);620-624 Included

Lin Li

Hai Nan Yi Xue 2011;22(15);143-144 Excluded

Liu Jianhong

Shi Yong Gan Zang Bing Za Zhi 2008;11(2);107-109 Excluded

Case series type II (10)

The Third People's Hospital of Changzhou

Gong Jing

Zhong Xi Yi Jie He Gan Bing Za Zhi 2012;22(3);144-145 Included

Supplementary Table 2. Information of 56 case reports

First author

Journal (Year) Affiliations ProvincesNo. Pts.

Admission date of cases

Not reported

Jian Kang Guan Li (2014)Zhong Da Hospital Affiliated to Dongnan University

Hunan 1 Not reported

Cao Haixia

Zhong Guo Yi Xue Qian Yan Za Zhi (2012)Xinhuang Hospital Affiliated to Shanghai Jiaotong University Medical College

Shanghai 1 Not reported

Cao Zhe

Zhong Guo Fa Yi Xue Hui Fa Yi Lin Chuang Xue Xue Shu Yan Tao Hui (2003)

Anshan City Public Security Bureau Criminal Investigation Detachment

Liaoning 1 1999.12

2013.1.12Chen Shanglin

Lin Chuang Xiao Hua Bing Za Zhi (2013)Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

Hubei 22013.2.27

2000.8.8Chen Weixing

Zhong Hua Gan Zang Bing Za Zhi (2005)The First Hospital Affiliated to Zhejiang University Medical College

Zhejiang 22002.9.11

2009.5.22Cheng Danying

Zhong Guo Gan Zang Bing Za Zhi (2012)Beijing Ditan Hospital Affiliated to Capital Medical University

Beijing 22009.6.4

2011.12.4

2013.2.11Cong Ming

Dang Dai Yi Xue (2014) Wendeng City People's Hospital Shandong 3

2013.2.22

Dai ning

Zhong Hua Xiao Hua Za Zhi (2007)Sir Run Run Shaw Hospital Affiliated to Zhejiang University Medical College

Zhejiang 1 Not reported

2008.9.30Dong Qunya

Zhong Hua Xian Dai Hu Li Za Zhi (2011)The First Hospital Affiliated to Zhejiang University Medical College

Zhejiang 22008.10.8

Fang Jiman

Zhong Hua Lin Chuang Yi Shi Za Zhi (2013) Tongling County People's Hospital Anhui 1 Not reported

2005.12.14

2006.6.12Fang Long

Zhong Ri You Hao Yi Yuan Xue Bao (2010) The China-Japan Friendship Hospital Beijing 3

2009.7.9Guo Qingbo

Shan Xi Zhong Yi (2009) Tianjin University of TCM Tianjin 1 2007.4.13

Hong Yong Gui Zhou Yi Yao (2012) Chishui City People's Hospital Guizhou 1 2011

2008.3Hou Yu

Hu Li Yan Jiu (2011)Nanjing General Hospital of Nanjing Military Command

Jiangsu 22009.2

Not reportedHu Jinsong

Zhong Guo Ling Chuang Yi Xue Ying Xiang Za Zhi (2014)

Affiliated Hospital of Shaoxing College of Arts and Science

Zhejiang 2Not reported

Hua Jing

Wei Chang Bing Xue (2010)Renji Hospital Affiliated to Shanghai Jiaotong University Medical College

Shanghai 1 Not reported

2004.12.31

2006.3.23Huang Huanjun

Lin Chuang Xiao Hua Bing Za Zhi (2008)Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

Hubei 3

2006.10.3

Lai RuiminLan Zhou Da Xue Shuo Shi Xue Wei Lun Wen (2013)

Lanzhou University Gansu 1 2012.6.12

LiChen

Gan Zang (2010)PLA 302 Hospital Liver Failure Treatment Research Center

Beijing 1 2009.4.16

Li Hong

Zhong Hua Hu Li Xue Hui 2009 Nian Quan Guo Hu Li Guan Li Xue Shu Jiao Liu Ji Zhuan Ti Jiang Zuo Hui Yi (2009)

Huangshi City Fifth Hospital Hubei 1 Not reported

2008.6.27Li Hong

Zhong Guo Ling Chuang Yi Xue (2009)Zhongshan Hospital Affiliated to Fudan University

Shanghai 22008.12.26

Li Jianping Zhong Hua Gan Dan Wai Ke Za Zhi (2001)The Second People's Hospital of Wuxi City

Jiangsu 1 Not reported

2007.1.20Li Libo

Chuan Ran Bing Zhen Zhi Gao Feng Lun Tan Ji 2007 Nian Zhe Jiang Sheng Gan Ran Bing Xue, Gan Bing Xue Xue Shu Nian Hui (2007)

Lishui City People's Hospital Zhejiang 22007.3.8

Li Shangri Zhong Xi Yi Jie He Gan Bing Za Zhi (2007) The Second Hospital of Huangshi City Hubei 1 2006.6

Li Xinqiao

Qiu Yi Wen Yao (2012) Not reportedNot reported

1 Not reported

2004.12.24Li Yuxiang Lin Chuang Gan Dan Bing Za Zhi (2006) First Hospital of Jilin University Jilin 2

2005.1.24

Li Zhimin

Zhong Hua Nei Ke Za Zhi (2005)The Second Hospital Affiliated to Zhejiang university Medical College


Liang Daming

Shan Dong Zhong Yi Za Zhi (2011) Xinchang County TCM Hospital Zhejiang 1 2010.6.9

2007.2 ~ 2009.1Liang

JianliHu Li Xue Bao (2009) Lishui City Central Hospital Zhejiang 2

2007.2 ~ 2009.1

Lin Ge

Journal of HepatologySchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong

Hong Kong 1 Not reported

Liu Huiyan Jian Kang Bo Lan (2011)Gulou Hospital Affiliated to Nanjing University Medical College

Jiangsu 1 Not reported

Lu Dan

Hu Li Yu Kang Fu (2013)The First Hospital Affiliated to Zhejiang University Medical College

Zhejiang 1 2012.1.12

2005.11.1Pan Jinhui Jiang Xi Zhong Yi Yao (2008) Xianju TCM Hospital, Taizhou Zhejiang 2

2007.11.2

Pei Yigang

Fang She Xue Shi Jian (2008)Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

Hubei 1 Not reported

Peng PeiliGong Neng Yu Fen Zi Yi Xue Ying Xiang Xue (2012)

PLA 155 Central Hospital, Kaifeng Henan 1 2010.2.19

2012.3.5Shi Yunzhen

Jian Kang Bi Du (2012) Dongyang City People's Hospital Zhejiang 22012.1.26

Sun DebenZhe Jiang Yi Xue Hui 2007 Nian Feng Shi Bing Nian Hui (2007)

The First Hospital Affiliated to Zhejiang University Medical College


Sun Lingjun

Zhong Guo Yi Yuan Yao Xue Za Zhi (2011)Nanjing General Hospital of Nanjing Military Command

Jiangsu 1 2009.12.14

2010.12.30Sun Lu

Wei Chang Bing Xue He Gan Bing Xue Za Zhi (2014)

The Second Affiliated Hospital of Xi'an Jiaotong University

Shanxi 22013.5.13

2010.11.3Tang Xiaogang

Zhong Guo Xiang Cun Yi Yao Za Zhi (2011) Tiantai County People's Hospital Zhejiang 22010.12.20

Tian Gengshan

Jia Ting Yi Yao (2014)The First Hospital Affiliated to Beijing University

Beijing 1 Not reported

2011.7.20Wang Zhibing

Zhong Guo Yi Shi Za Zhi (2012)Nanjing Hospital Affiliated to Nanjing Medical University

Jiangsu 22011.10.14

Wang Li

Zhong Guo Yi Xue Gong Cheng (2013) Yantai Yuhuangding Hospital Shandong 1 Not reported

Wang Qiang

Xian Dai Yi Xue (2011) Jiangyin City Xu Xiake Hospital Jiangsu 1 Not reported

2005.7.13

2005.12.17

2005.12.23Wu Xinjun

Zhong Hua Gan Zang Bing Za Zhi (2007) Xinchang County People's Hospital Zhejiang 4

2006.1.12

Wu Yiqun

Quan Ke Yi Xue Lin Chuang Yu Jiao Yu (2012) Second Hospital of Yinzhou, Ningbo Zhejiang 1 2010.12.28

Xiao Yujie Xu Zhou Yi Xue Yuan Xue Bao (2010) Xuzhou Medical College Jiangsu 1 2009.6.22

Yan Hong

Shi Yong Gan Zang Bing Za Zhi (2005)Jinggangshang University Affiliated Hospital

Jiangxi 1 Not reported

2006.11Yan Ying

Zhong Xi Yi Jie He Gan Bing Za Zhi (2009)Zhejiang Provincial Hospital of Traditional Chinese Medicine

Zhejiang 22007.3

Yang Bao

Yi Yao Qian Yan (2012) Dali Prefecture People's Hospital Yunnan 1 2011.7.26

2009.6.4Yang Sai

Xin Zhong Yi (2011)Guangzhou University of Chinese Medicine

Guangdong 22009.5.21

2011.10.Zhang Huamei

Qi Qi Ha Er Yi Xue Yuan Xue Bao (2013)The Third People's Hospital of Zhenjiang City

Jiangsu 22012.1

Zhang Qianqian

Xian Dai Zhong Xi Yi Jie He Za Zhi (2011)The First Bethune Hospital of Jilin University

Jilin 1 2006.5

Zhang Yanling

Bei Jing Yi Xue (2011) Children's Hospital Affiliated to Capital Institute of Pediatrics

Beijing 2 2008.10.27

Yanling Institute of Pediatrics 2009.8.29

Zhou Yanping

Yao Wu Bu Liang Fan Ying Za Zhi (2012) 302 Military Hospital of China Beijing 1 2011.12.14

Zhu Xiansheng

Zhong Hua Yi Xue Hui Di Shi Ci Quan Guo Chao Sheng Yi Xue Xue Shu Hui Yi (2009)

Guangzhou General Hospital of Guangzhou Military Command

Guangdong 1 Not reported

Supplementary Table 3. Study quality of 84 case reports

First author Q1 Q2 Q3 Q4 Q5 Q6

Not reported NA Yes Yes Yes No No

Cao Haixia NA Yes Yes Yes No No

Cao Zhe NA Yes Yes Yes No Yes

case 1 NA Yes Yes Yes Yes YesChen Shanglin

case 2 NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesChen Weixing


case 1 NA Yes Yes Yes Yes YesCheng Danying



case 2 NA Yes Yes Yes Yes YesCong Ming


Dai ning NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesDong Qunya


Fang Jiman NA Yes Yes Yes Yes Yes


case 2 NA Yes Yes Yes Yes YesFang Long


Guo Qingbo NA Yes Yes Yes Yes Yes

Hong Yong NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesHou Yu


case 1 NA Yes Yes Yes Yes YesHu Jinsong


Hua Jing NA Yes Yes Yes Yes Yes


case 2 NA Yes Yes Yes Yes YesHuang Huanjun


Lai Ruimin NA Yes Yes Yes Yes Yes

Li Chen NA Yes Yes Yes Yes Yes

Li Hong NA Yes Yes Yes Yes No

case 1 NA Yes Yes Yes Yes YesLi Hong


Li Jianping NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesLi Libo


Li Shangri NA Yes Yes Yes No No

Li Xinqiao NA Yes Yes Yes No No

case 1 NA Yes Yes Yes Yes YesLi Yuxiang


Li Zhimin NA Yes Yes Yes Yes Yes

Liang Daming NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesLiang Jianli


Liu Huiyan NA Yes Yes Yes No No

Lu Dan NA Yes Yes Yes Yes YesPan Jinhui case 1 NA Yes Yes Yes Yes Yes


Pei Yigang NA Yes Yes Yes No No

Peng Peili NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesShi Yunzhen


Sun Deben NA Yes Yes Yes Yes Yes

Sun Lingjun NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesSun Lu


case 1 NA Yes Yes Yes Yes YesTang Xiaogang


Tian Gengshan NA Yes Yes Yes No No

case 1 NA Yes Yes Yes Yes YesWang Zhibing


Wang Li NA Yes Yes Yes No No

Wang Qiang NA Yes Yes Yes Yes Yes



case 3 NA Yes Yes Yes Yes YesWu Xinjun


Wu Yiqun NA Yes Yes Yes Yes Yes

Xiao Yujie NA Yes Yes Yes Yes No

Yan Hong NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes No NoYan Ying


Yang Bao NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesYang Sai


case 1 NA Yes Yes Yes Yes YesZhang Huamei


Zhang Qianqian NA Yes Yes Yes Yes Yes

case 1 NA Yes Yes Yes Yes YesZhang Yanling

case 2 NA Yes Yes Yes No Yes

Zhou Yanping NA Yes Yes Yes Yes Yes

Zhu Xiansheng NA Yes Yes Yes Yes Yes

Lin Ge NA Yes Yes Yes Yes Yes

Supplementary Table 4. Information of 31 case series (type I)

First author

Journal (Year) Affiliations ProvinceNo. Pts

Periods

Cai Shaolong

Zhong Guo Shi Yong Yi Yao (2013) Jieyang People's Hospital Guangdong 102010~ 2012

Chen Hongtan

Zhe Jiang Sheng Zhong Xi Yi Jie He Xue Hui Xiao Hua Zhuan Ye Di Ba Ci Xue Shu Nian Hui Ji Sheng Zhong Xi Yi Jie He Xiao Hua Xi Ji Bing Xin Jin Zhan Xue Xi Ban (2007)


Zhejiang 201996.1~ 2006.9

Chen Huazhong

Lin Chuang Gan Dan Bing Za Zhi (2012)Taizhou Hospital Affiliated to Wenzhou Medical College

Zhejiang 451998.1~ 2011.5

Gao Hong Journal of Digestive Diseases (2012)Zhongshan Hospital Affiliated to Fudan University

Shanghai 52006.1~ 2010.8

Gu Chao Zhong Hua Xiao Hua Za Zhi (2010)Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School

Jiangsu 72008.6~ 2010.5

Guo Wei Zhong Hua Ling Chuang Yi Shi Za Zhi (2012) Air Force General Hospital of PLA Beijing 52011.9~ 2012.3

Hu Zhibin Zhong Guo CT He MRI Za Zhi (2011) Yingcheng People's Hospital Hubei 52006~ 2011

Huang Jiguo

Xian Dai Zhong Xi Yi Jie He Za Zhi (2009) Yangzhou Hongquan Hospital Jiangsu 82004.8~ 2008.4

Jin Ruijun Yi Xue Ying Xiang Xue Za Zhi (2014)Xinchang County Hospital of Traditional Chinese Medicine

Zhejiang 162008.1~ 2013.5

Li Liangping

Zhong Guo Xian Dai Yi Sheng (2012)Affiliated Hospital of Medical College of Jiaying University

Guangdong 122005.6~ 2012.6

Ma Xinguang

Zhe Jiang Lin Chuang Yi Xue (2008) Xianju County People's Hospital Zhejiang 161996.12~ 2006.12

Qiao Yan Dang Dai Hu Shi (2014) The First People's Hospital of Yancheng Jiangsu 62008.1~ 2013.6

Wu Xingwang

An Hui Yi Ke Da Xue Bo Shi Xue Wei Lun Wen (2012)

Anhui Medical University Anhui 102007.3~ 2010.2

Xu Haibo Zhong Guo Xiang Cun Yi Yao (2010) Xianju County People's Hospital Zhejiang 142005.1~ 2009.12

Xu Meimei

Lin Chuang Hui Cui (2007) The First Hospital of Qinhuangdao Hebei 62003.1~ 2007.1

Xu Xiaojun

Zhong Hua Wei Zhong Zheng Yi Xue Za Zhi (2010)

Wuyi County Hospital of Traditional Chinese Medicine

Zhejiang 422006.1~ 2009.12

Xue Xinquan

Jiang Su Yi Yao (2014)The First Affiliated Hospital of Nanjing Medical University

Jiangsu 52006~ 2014

Yang Chunjing

Shi Yong Fang She Xue Za Zhi (2014) The First People's Hospital of Jiujiang Jiangxi 42011.7~ 2013.6

Yang Jianjun

Yi Xue Ying Xiang Xue Za Zhi (2010)The First Affiliated Hospital of Suzhou University

Jiangsu 322000.7~ 2009.11

Yang Li Gan Zang (2009)The Second Xiangya Hospital of Central South University

Hunan 62005.1~ 2008.12

Yao Lidi Xian Dai Shi Yong Yi Xue (2012) Huzhou Central Hospital Zhejiang 172004.6~ 2010.1

Yao Lingdi

Xian Dai Zhong Xi Yi Jie He Za Zhi (2014) The Third People's Hospital of Changzhou Jiangsu 162005.1~ 2012.12

Ye Tianhe Hua Dong Ke Ji Da Xue Shuo Shi Xue Wei Lun Wen (2013)

Xiehe Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology

Hubei 202010.4~ 2012.7

Ye Yuzhu Hu Shi Jin Xiu Za Zhi (2013)Lishui Hospital of Traditional Chinese Medicine

Zhejiang 42006.10~ 2012.5

Yu ShunZhong Guo Yi Xue Ying Xiang Xue Za Zhi (2013)

Zhongshan Hospital Affiliated to Fudan University; Fujian Provincial Hospital

Shanghai; Fujian

62002.11~ 2012.2

Zhang Kui Zhe Jiang Zhong Xi Yi Jie He Za Zhi (2013) Xinchang County People's Hospital Zhejiang 182005.2~ 2012.6

Zhang Zhiqin

Zhe Jiang Zhong Yi Za Zhi (2007)Xianju County Hospital of Traditional Chinese Medicine

Zhejiang 172002.6~ 2007.3

Zhong Lan

Jiang Xi Yi Yao (2012)The First Affiliated Hospital of Nanchang University

Jiangxi 52008.1~ 2011.10.

Zhou Hua Korean Journal of Radiology (2014)The First Affiliated Hospital of Zhejiang University Medical College

Zhejiang 162009.8~ 2011.2

Zhu Xianjin

Lin Chuang Fang She Xue Za Zhi (2011)The China-Japan Friendship Hospital Ministry of Health

Beijing 32005 ~ 2009

Zhu Xiuqin

Hu Li Yan Jiu (2011)Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology

Hubei 62004.12~ 2009.12

Supplementary Table 5. Quality of 31 case series (type I)


Cai Shaolong No Yes Yes Yes Yes Yes

Chen Huazhong No Yes Yes Yes Yes Yes

Gao Hong No Yes Yes Yes No Yes

Gu Chao No Yes Yes Yes Yes Yes

Guo Wei No Yes Yes Yes Yes Yes

Hu Zhibin No Yes Yes Yes Yes Yes

Huang Jiguo No Yes Yes Yes Yes Yes

Ma Xinguang No Yes Yes Yes Yes Yes

Qiao Yan No Yes Yes Yes Yes Yes

Xu Haibo No Yes Yes Yes Yes Yes

Xu Meimei No Yes Yes Yes Yes Yes

Xu Xiaojun No Yes Yes Yes Yes Yes

Yang Chunjing No Yes Yes Yes Yes Yes

Yang Li No Yes Yes Yes Yes Yes

Yao Lingdi No Yes Yes Yes Yes Yes

Ye Tianhe No Yes Yes Yes Yes Yes

Ye Yuzhu No Yes Yes Yes Yes Yes

Zhang Zhiqin No Yes Yes Yes Yes Yes

Zhong Lan No Yes Yes Yes Yes Yes

Zhu Xiuqin No Yes Yes Yes Yes Yes

Supplementary Table 6. Information of 19 case series (type II)

First author

Journal (Year) Affiliations Province Periods

Ding Pengpeng

Jie Fang Jun Yi Xue Yuan Xue Bao (2013)

Peoples Liberation Army General Hospital Beijing2003.8~ 2012.5

Gong Jing

Zhong Xi Yi Jie He Gan Bing Za Zhi (2012)

The Third People's Hospital of Changzhou Jiangsu2005.1~ 2010.7

Gu Meichun

Qi Qi Ha Er Yi Xue Yuan Xue Bao (2004)

Xianju County People's Hospital Zhejiang1999.1~ 2003.5

Guo Wei

Da Lian Yi Ke Da Xue Shuo Shi Xue Wei Lun Wen (2013)

Air Force General Hospital, PLA Beijing2011.9~ 2012.12

Jiang Tian'an

Zhong Guo Chao Sheng Yi Xue Za Zhi (2008)


Zhejiang2000.8~ 2007.9

LiZeng

Zhong Guo CT He MRI Za Zhi (2014) Affiliated Hospital of Xuzhou Medical College Jiangsu2011.8~ 2014.2

Li Hong

Di Er Shi Yi Ci Quan Guo Zhong Xi Yi Jie He Gan Bing Xue Shu Hui Yi (2012)

Affiliated Hospital of Guiyang Medical College

Guizhou2010.2~ 2012.3

Li Ling

Hu Li Xue Za Zhi (2013)Xiehe Hospital Affiliated to Tongji Medical college Huazhong University of Science and Technology

Hubei2010.1~ 2013.1

Li Xiaoqin

Hu Shi Jin Xiu Za Zhi (2014) Taizhou People's Hospital Jiangsu2009.4~ 2013.5

Li Yang

Lin Chuang Gan Dan Bing Za Zhi (2011)

The First Affiliated Hospital of Anhui Medical University

Anhui2007.6~ 2010.2

Li Yujiang

Zhong Guo Lin Chuang Yan Jiu (2012)Drum Tower Hospital Affiliated to Nanjing University Medical School

Jiangsu2005.6~ 2011.6

Li Yunfang

Ci Gong Zheng Cheng Xiang (2011)Beijing Youan Hospital, Capital Medical University

Beijing2009.4~ 2011.8

Wang Junyao

Shou Du Yi Ke Da Xue Xue Bao (2014) Peking University People's Hospital Beijing2009.10~ 2014.8

Xun Yunhao

Zhong Hua Zhong Yi Yao Xue Hui Quan Guo Di Shi Si Ci Gan Dan Bing Xue Shu Hui Yi (2010)

The Sixth People's Hospital of Hangzhou ZhejiangNot reported

Zhang Genhua

Yi Xue Ying Xiang Xue Za Zhi (2012) Sanmen People's Hospital Zhejiang2006.2~ 2010.3

Zhang Jingjing

Shi Yong Yi Xue Za Zhi (2011) Lishui People's Hospital Zhejiang2007.10~ 2010.5

Zhang Wei

Zhong Guo Xian Dai Pu Tong Wai Ke Jin Zhan (2014)

General Hospital of Armed Police Forces Beijing2005.9~ 2011.12

Zhang Yanting

Lin Chuang Gan Dan Bing Za Zhi (2013)

The First Affiliated Hospital of Nanjing Medical University

Jiangsu2008.8~ 2013.5

Zhu Wanlin

Zhong Hua Xiao Hua Za Zhi (2012)The First Affiliated Hospital of Zhejiang University Medical College

Zhejiang2008.8~ 2011.8

Supplementary Table 7. Quality of 19 case series (type II)


Ding Pengpeng No Yes Yes Yes Yes Yes

Gong Jing No Yes Yes Yes Yes Yes

Gu Meichun No No Yes Yes No No

Guo Wei No Yes Yes Yes No No

Jiang Tian'an No Yes No Yes No No

Li Zeng No Yes No Yes No No

Li Hong No No Yes No No No

Li Ling No Yes Yes Yes Yes Yes

Li Xiaoqin No Yes Yes No Yes Yes

Li Yang No Yes Yes Yes Yes Yes

Li Yujiang No Yes Yes Yes Yes Yes

Li Yunfang No Yes Yes Yes Yes No

Wang Junyao No Yes Yes Yes Yes Yes

Xun Yunhao No Yes Yes Yes Yes Yes

Zhang Genhua No Yes No Yes No No

Zhang Jingjing No Yes No Yes Yes Yes

Zhang Wei No Yes Yes Yes Yes Yes

Zhang Yanting No Yes Yes Yes Yes Yes

Zhu Wanlin No Yes Yes Yes Yes Yes

Supplementary Figure 1. Forest plot showing the proportion...

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