Supplemental information A Potential of hyphenated ultra ...

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Supplemental information A Potential of hyphenated ultra-high performance liquid chromatography-scheduled multiple reaction monitoring algorithm for large-scale quantitative analysis of traditional Chinese medicines Qingqing Song, a,b,# Yuelin Song, a,#, * Na Zhang, a,b Jun Li, a Yong Jiang, c Kerong Zhang, d Qian Zhang, a and Pengfei Tu a * a Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China; b School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China; c State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; d Application Support Center, AB SCIEX, Shanghai 200233, China. # These two authors contribute equally to this article. *Correspondence to: Dr. Yuelin Song, E-mail address: [email protected], Tel./fax: +86-10-64286100 Prof. Pengfei Tu, E-mail address: [email protected], Tel./fax: +86-10-82802750. Figure legends Fig. S1 Overlaid extracted ion current (EIC) chromatograms of all 70 ion transitions monitored under positive polarity and all for 196 ion transitions monitored under negative polarity for eight raw materials, including Ginseng Radix, Aconiti Lateralis Radix Praeparata, Solani Melongenae Radix, Pheretima, Galli Gigerii Endothelium Corneum, Cistanches Herba, Polygalae Radix, and Draconis Resina. Electronic Supplementary Material (ESI) for RSC Advances. This journal is © The Royal Society of Chemistry 2015

Transcript of Supplemental information A Potential of hyphenated ultra ...

Supplemental information A

 

Potential  of  hyphenated  ultra-high  performance liquid 

chromatography-scheduled multiple  reaction  monitoring  algorithm 

for large-scale quantitative analysis of traditional Chinese medicines

 Qingqing Song,a,b,# Yuelin Song,a,#,* Na Zhang,a,b  Jun Li,a  Yong Jiang,c Kerong Zhang,d Qian 

Zhang,a and Pengfei Tu a*

 a Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese 

Medicine, Beijing 100029, China;b School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, 

China;c State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, 

Peking University, Beijing 100191, China;d Application Support Center, AB SCIEX, Shanghai 200233, China.

 # These two authors contribute equally to this article.

 

*Correspondence to: 

Dr. Yuelin Song, E-mail address: [email protected], Tel./fax: +86-10-64286100

Prof. Pengfei Tu, E-mail address: [email protected], Tel./fax: +86-10-82802750.

Figure legends

Fig. S1 Overlaid extracted ion current (EIC) chromatograms of all 70 ion transitions 

monitored under positive polarity and all for 196 ion transitions monitored under negative 

polarity for eight raw materials, including Ginseng Radix, Aconiti Lateralis Radix 

Praeparata, Solani Melongenae Radix, Pheretima, Galli Gigerii Endothelium Corneum, 

Cistanches Herba, Polygalae Radix, and Draconis Resina. 

Electronic Supplementary Material (ESI) for RSC Advances.This journal is © The Royal Society of Chemistry 2015

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Ginseng Radix in positive polarity

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Aconiti Lateralis Radix Praeparata in positive polarity

Aconiti Lateralis Radix Praeparata in negative polarity

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Solani Melongenae Radix in positive polarity

Solani Melongenae Radix in negative polarity

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Pheretima in positive polarity

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Galli Gigerii Endothelium Corneum in positive polarity

Galli Gigerii Endothelium Corneum in negative polarity

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Cistanches Herba in positive polarity

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Polygalae Radix in positive polarity

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Draconis Resina in positive polarity

Draconis Resina in negative polarity