SuperCharged Podcast...SuperCharged Podcast: Page 1 SuperCharged Podcast Gut microbiome and wellness...
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SuperCharged Podcast: Page 1 SuperCharged Podcast Gut microbiome and wellness with Naveen Jain 00:00:30 Meet Naveen Jain 00:01:30 Naveen’s health mission 00:04:00 When your body is not at ease, you get dis-ease 00:06:00 All chronic diseases have this one thing in common 00:07:20 The problem with the health and education systems 00:09:40 The healthcare system is designed to keep you sick 00:11:20 Gut microbiome is to blame for disease, not genes 00:13:20 Research shows breast cancer caused by microbiome 00:16:15 70% of our immune system is right around the gut 00:17:40 There is no such thing as a universal healthy diet 00:22:40 Why these fad diets are killing people 00:23:30 Our microbiome is more unique than our fingerprint 00:32:00 Causative studies of the microbiome 00:37:40 How our behavior is determined by our microbiome 00:42:00 Could it be that the human body doesn’t really exist? 00:45:00 Understanding what Viome does 00:49:30 How Viome will use artificial intelligence to help solve health Harry Massey: Welcome to the Supercharged Podcast, where we help you to enhance your energy, health, and purpose. Wendy Myers: Bioenergetics is truly the future of medicine. Harry: [00:00:30] Imagine having a body charged with energy and a mind quick as lightning. Is that a superhero? No, that's you, supercharged. We'll be talking to experts who have studied the physics of life so that you can have energy for life. Thank you for tuning into the Supercharged Podcast I'm really excited today because we're here with Naveen Jain, who's an entrepreneur and philanthropist, who's really driven to solve the world's biggest challenges through innovation. Although he's been behind a number of really successful companies like the World Innovation Institute, Inome, Talentwise, Intelius and Viome, the reason why I'm particularly excited to talk to Naveen today is really because of his work with Viome and basically how we're looking at the bacteria in the gut, which is also acting as a communication system across the body. Welcome Naveen, and I'm really looking forward to finding out more. Naveen Jain: Thanks a lot Harry. It's been a pleasure to be here with you and looking forward to our conversation.
Transcript of SuperCharged Podcast...SuperCharged Podcast: Page 1 SuperCharged Podcast Gut microbiome and wellness...
SuperCharged Podcast: Page 1
SuperChargedPodcastGut microbiome and wellness with Naveen Jain
00:00:30 MeetNaveenJain00:01:30 Naveen’shealthmission00:04:00 Whenyourbodyisnotatease,yougetdis-ease00:06:00 Allchronicdiseaseshavethisonethingincommon00:07:20 Theproblemwiththehealthandeducationsystems00:09:40 Thehealthcaresystemisdesignedtokeepyousick00:11:20 Gutmicrobiomeistoblamefordisease,notgenes00:13:20 Researchshowsbreastcancercausedbymicrobiome00:16:15 70%ofourimmunesystemisrightaroundthegut00:17:40 Thereisnosuchthingasauniversalhealthydiet00:22:40Whythesefaddietsarekillingpeople00:23:30 Ourmicrobiomeismoreuniquethanourfingerprint00:32:00 Causativestudiesofthemicrobiome00:37:40 Howourbehaviorisdeterminedbyourmicrobiome00:42:00 Coulditbethatthehumanbodydoesn’treallyexist?00:45:00 UnderstandingwhatViomedoes00:49:30 HowViomewilluseartificialintelligencetohelpsolvehealth
HarryMassey: WelcometotheSuperchargedPodcast,wherewehelpyoutoenhanceyourenergy,health,andpurpose.
WendyMyers: Bioenergeticsistrulythefutureofmedicine.
Harry:[00:00:30]
Imaginehavingabodychargedwithenergyandamindquickaslightning.Isthatasuperhero?No,that'syou,supercharged.We'llbetalkingtoexpertswhohavestudiedthephysicsoflifesothatyoucanhaveenergyforlife.ThankyoufortuningintotheSuperchargedPodcastI'mreallyexcitedtodaybecausewe'reherewithNaveenJain,who'sanentrepreneurandphilanthropist,who'sreallydriventosolvetheworld'sbiggestchallengesthroughinnovation.Althoughhe'sbeenbehindanumberofreallysuccessfulcompaniesliketheWorldInnovationInstitute,Inome,Talentwise,InteliusandViome,thereasonwhyI'mparticularlyexcitedtotalktoNaveentodayisreallybecauseofhisworkwithViomeandbasicallyhowwe'relookingatthebacteriainthegut,whichisalsoactingasacommunicationsystemacrossthebody.WelcomeNaveen,andI'mreallylookingforwardtofindingoutmore.
NaveenJain: ThanksalotHarry.It'sbeenapleasuretobeherewithyouandlookingforwardtoourconversation.
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Harry:[00:01:30]
Perfect.Shallwejustgostraightin?Ithinkyourstatedmissionistomakeillnessachoiceforasmuchofhumanityaspossible.I'dlovetoknowwhyisthatyourmissionandhowdidyou,Iguess,comeoutfrombuildingsoftwarecompaniestowantingtosolvetheworld'sbiggesthealthproblems?
Naveen:
Asyoustarttolookatthestuffandsayingforthefirsttimeinthehumanhistory,theindividualsandasmallgroupofpeoplehaveaccesstotechnologythattheyneverhadbefore.Asmallgroupofpeoplearenowcapableofdoingthingsthatonlythenationstatesorsuperpowerscoulddobefore,whetheritisgoingtospace...thatwasconsideredthedomainofnotonlytherichestcountries,butonlythesuperpowerswhocoulddothat.Here,wearesittingheretoday,wherethisraceisbeingexploredbyentrepreneurs.Asyouknow,oneofmyothercompanies,MoonExpress,whichistheonlycompanyintheuniversethathaspermissiontoleaveEarthorbitandlandontheMoon.ImaginewelandontheMoon,notonlynextyear,webecomethefirstcompanytodoso,butmoreimportantlywebecomesymbolicallythenextsuperpower,thefourthsuperpower,tohaveachievedafeat.
Comingbacktoit,itisjustnotthespace.Thatistheliteralmoonshot.MynextMoonshotiswhatifwecanclearaworldwheresicknesswasachoice.ThereasonthatIsaythatisIdidn'tsaythatwecancreateaworldwherenoonewillbesickbecausethatshowsthatpowerliesinmetocreatethatworld.WhatIamtryingtosaythatiswhatifwecanempowereachindividual,tellthemexactlywhatisgoingoninsidetheirbody,becauseweare,toalargeextent,anecosystem,andasIthinkwe'regoingtogetintoit,andhowthisecosystemcommunicatesamongstitselfsothereisnomorecompartmentalizedsubsystemcalledheartandkidneyandliverandyourgut.Theyallworktogetherasonesystemandthey'reconstantlycommunicating.Thereisalwaystheweakestlinkand,asweknow,whenyoustress
[00:04:00] thesystem,italwaysbreaksattheweakestlink.Ourjobistounderstandwhatisgoingoninsidethebody?Finally,wehavethetechnologyatourdisposalthatallowsyoutoseeeverythingthat'shappeninginthebody,andwe'regoingtogetintomoredetailonthat.Notonlybecauseknowingthatisgood,butreallywhatmattersiswhatcanyoudoaboutit?Howdoyoumodulatethecommunication?Howdoyoumodulatetheproductionofdifferentenzymesanddifferentchemicals.
Ifyoucancontrolthat,thenyoucankeepthatbodyworkinginbalance,becauseattheendoftheday,whenyourbodyisinbalance,itisatease,andwhenyourbodyisnotatease,whatwegetisdis-ease,whichisadisease.Ourgoalwastoempowerindividualstomakeachoiceofwhethertheywanttobesickornot.Ican'tmakethatchoiceforthem.
Harry:
Perfect,tosummarizeit,foryoutosolvethishugehealthchallenge,it's,A,helppeoplegettotherootcauseandknowwhat'sgoingonintheirbody,andthenB,educatethemwithwhattodoaboutit.Wouldthatsumitup?
Naveen:
That'smoreorlessyes,buttoalargeextentwhenyoutalkabouttherootcause,I'mnottalkingaboutthatwesomehowhavethesilverbulletandifyoucanfindasilverbullet,everythingwillbefine.Whatwe'rereallysayingisthatallofthechronicdiseasesfundamentallyhaveonethingincommon,whichisthechronic
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inflammation.WhetherwelookatAlzheimerorautismorParkinson's,youlookatanxietyandyoulookatdepressionorPTSDoryoustarttolookatobesityordiabetesorautoimmunediseasesorevencancer.Theseareallessentiallyinflammatorydiseases.Inflammationhappenswhenourimmunesystemssays,"Idon'tknowwhatisgoingon.Thereissomethingbadgoingon,andonewaytogetridofwhateverthebadthingistoinflamethebodytogetridofthis,theycallforeign-agenttoxins."Intheirmindit'satoxin.Sometimestheystarttobelieveour
owncells...Ourcellsreallyistheonethat'scausingproblem,andthat'swhat'scausedautoimmunedisease.What'sreallyhappeningisifwecanunderstandwhatisinflammation,whatiscausingthatinflammationandifwecanreduceeverythingthat'scausinginflammation,yourbodywillessentiallybeatcalm,ateaseandthatiswe'regoingtohavenodisease.
Harry:
Perfect.Obviously,amassivepartofthatistheneducatingpeoplewithwhattodowiththatknowledge.Oncethey'veidentifiedwhat'sbehindtheinflammation...Ithinkeducationisalsooneofyourotherkeypassions.I'mcurioushowthattiesintoyourhealthmission.HowdoweundothenegativeeducationfromIguessbigpharmaintodoctorsandthepowerofdoctors?Iwascurioushowyou'rethinkingabouttacklingtheactualeducativepartofthismission.
Naveen:[00:07:20]
Ifyoustarttothinkabout,whetheryoulookatthehealthcareandyoulookatoureducationsystem,theyhavelotofsimilaritiesintheminasensethatpeoplebelievethatinneithertheeducationsystemnorthehealthcaresystemisworkingwellforthem.Theybelieveboththesystemsarebroken.Itturnsoutactuallyneitherofthesystemsareactuallybroken.They'redoingexactlywhattheyweredesignedtodoexceptthatourneedstodayareverydifferentthantheneedsthatweretheresay100yearsago.Forexample,oureducationsystemwasdesignedfor
theindustrialera,wherewewantedtocreateacertaintypeofpeople.Thatmeanswewantedthecertainskillsanditwasdesignedtoteachyouskillsandthoseskillscouldbeusedforrestofyourlife.Itwasdesignedessentiallyforplugandplaysystem."Ineedsevenaccountants.Ineed10peoplewithmachineknowledge.Ineedfivecomputerscientists.Ineed10ofthese."Itdidn'tmatterwhothesepeoplewereaslongastheyhadthosesetofskillsthatcouldessentiallybeplugandplayedintothesystem.What’shappeningtodayiswiththewordofexponential
technologies,itdoesn'tmatterwhatskillyoulearn.Itbecomesobsoleteeveryfourtosixyears,soinmanycases,bythetimeyougraduatewiththisskill,thatskillisnolongerneeded.Thatskillhasalreadybecomeobsolete.That'swhywehavethisconceptthatwe'regoingtogetiswhatIcallchronicunemployment.Thatmeanswe'regoingtoconstantlybechronicallyunemployedbecausetheskillsthatwe'relearningarebecomingobsoletefasterthanwecanlearn.Thatmeanstheeducation
systemhastofundamentallychangelearningtolearn,howdoyouapplytheskill?Asopposedtohavingaindividualskill,howdoyouuseinterdisciplinaryknowledgetosolveaparticularproblem?Howdoyoucollaborate?Assumethatalltheknowledge,alltheskillsareonyourfingertips,onyourcellphone,whatwouldyoudonext?Itreallybecomesacompletelydifferentsystem,nothavingasageonthestage,assumetheknowledgeactuallybeingdeliveredtoyouinapersonalizedwaytoyou,thenwhatwouldyoudonext?
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Harry: Gotyou.
NaveenJain:[00:09:40]
Thesamethinghappensinthehealthcarenow.Wehavethissageonthestage.Yougetsickandwhenyouaresick,youfeelhelplessandyoufeelhopeless.Guesswhathappens?Anytimeyouarehelpless,somebodyisgoingtovictimizeyou.Today,ourhealthcaresystemdoesagreatjobofvictimizingyou.Wehavethishealthcaresystemthatisdesignedtokeepyousick.Thepharmaceuticalcompanieslovechronicdiseases.ChronicdiseasesmeansnowIhaveasubscriptionbusinessandevenoneoftheCEOforapharmaceuticalcompanysaid,"Thebestdrugthatwedeveloparethedrugsthatpeoplehavetotakeforrestoftheirlives."
ImagineforasecondwhatthispharmaceuticalcompanyCEOissayingis,"Welovekeepingpeoplesick.Wedon'twantthemtobecuredbecauseiftheygetcured,wecan'tmakemoneyfromthem."Wewantthemtobecured.Ourdoctorsdon'twantustobehealthyeitherbecausetheyonlygetpaidwhenwearesickandwegotothem.Ourhospitalswantustobesick.Ourinsurancecompanywantsustobesick.Thewholehealthcaresystemisreallybecomeanorganismwherethesurvivaloftheorganismiswhatmattersandthepurposeisoutthewindow.Thepatienttolargeextentinthissystemhasbecomeanuisancethattheyhavetodealwithjusttocollectthemoney.Theywouldrathernotdealwiththepatientiftheydon'thaveto.Whatourgoalwasforthefirsttime,weactuallyhavetechnologiesthatcantell
youwhatisgoingoninsideyourbodybetterthanthedoctorcaneverknow.Today,tolargeextent,ourmedicalsystem,eventhedoctorswhograduatetoday,aretoldsimply,"Findthesetofsymptom.Ifyoucannameadiseaseafterit,getainsurancecodeforitandthere'syourdrugforit."That'sall."Matchthesymptomtoadiseaseandthenmatchittoadrugandyourjobisdone."Whatsurprisesmemostisthat
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inthelastthreeyearstofiveyears,everysingleresearchpaperisshowingthateverysinglechronicdisease...YoucanlookatitfromParkinson'stoautismtoAlzheimer,obesity,diabetes,anxiety,depression,autoimmunediseasesorevencancerisnotcausedbyourgenes.It'sactuallycausedbythemicrobiomeinthegut.I'mgoingtocomebackinasecondandgetmoreintoit.Weareawalkingecosystem.Ourmedicalsystembelievesthehealthiestbodyistheonethatisdevoidofallthebacteriaandviruses.Naturehadsomethingelseinmind.
Infact,fromnature'sperspective,thebacteriaandvirusesarearoundforbillionsofyears.Thehumansareverynewtothisecosystem.Thehumansonlyevolvedashominids250,000yearsago.Bacteriaandvirusesbeenaroundandtolargeextent,ifyoulookatitfromtheperspectiveofthenature,wearereallyaportablecontainerforthisecosystem.Theyaretheonesthatareinsidethebody.OurhumanDNAonlyproduces20,000genesandthetrillionsofthesemicroorganismsthatarelargelyinsideourlargecolon,thelargeintestine,thegut,that'swhereallthesetrillionsoforganismsreside.Theyproduce5millionto10milliongenes.
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Thinkforasecondhere.Weare99%microbialecosystemandlessthan1%human.Tolargeextent,it'swhenyoulookatthedoctorwho'sgraduatingtoday,they'renoteventaughtaboutthemicrobiome.Imaginehereitis,whereeverydiseaseisbeingcausedandinfluencedbythem.Amonthago,therewasaresearchpublishedbytheClevelandClinicthatshowsthatbreastcanceriscausedbythemicrobiome.Theninthelasttwoweeks,intworesearchthatwerepublished,oneclearlyshowswhetherthechemotherapydrugsworksoritactuallykillsthepatientdependson
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yourmicrobiomeinyourgut.Immunotherapy,whetherit'santi-PD-1oranti-PL-1drug,whetheritactuallyworksorit'scompletelyuselessdependsonyourmicrobiome.TheydidthisstudyandshowsthatPTSDandOCDoreventhingslike
age-relatedmaculardiseaseormultiplesclerosis.Youpickanameyouwant,everyoneofthediseasesinfluencedbytheseorganismsthatareconstantlycommunicatingwithourbody.Themicrobiomeiscommunicatingwithourmitochondria.MicrobiomeiscommunicatingwithourhumancellsintermsofgeneexpressionbymodifyingthemicroRNAnotonlyinourbody,butalsoinourbrain.
TherewasaveryinterestingresearchthatIfoundthatactuallyshowsthathowourmicrobiomeismodifyingthemicroRNAintheamygdalaandprefrontalcortex.Imaginewhatthatmeans.Thatmeansthey'recontrollingourbehaviorandthey'recontrollingourdecisionmaking.Thenitstarttotellyouwhoisthemasterandwhoistheslavehere.
Harry: Absolutely.Iguessfromatechnologypointofview,whenpeopledotheViometestandtheygetresultsofhowtheycanimprovetheirmicrobiome,howareyouthinkingofeducatingpeopleonallofthehealthyhabitsthat'llhelpthemtobuildupthatmicrobiome?
Naveen:
Actually,it'smorethanmicrobiome,Harry.Whatreallycomesdowntoishowdoyoukeepthebodyinbalanceandwhereallthethingsareworkingproperlyandcommunicatingwelleachother.Alotofthediseaseshappenwhenthere'sacommunicationbreakdown.It'snodifferentthanhumans.Webothmaybedoingtherightthing,butifwearenotcommunicatingwell,webothactuallyendupbecomingtheenemiesbecausethecommunicationbreaksdown.Thesamethinghappensinourbody.WhatwedoatViomeissimplylookatwhatishappeningin
themicrobialecosystems.Wearenotabouttellingyou,"Herearealltheorganismsinyourgut."Welookateverystrainofeverybacteria,everyvirus,yeast,fungusandmold,butthattousjustthebeginning.Thenwelookatthisstuffandsay,"Howactivearethesethings?"Moreimportantly,whataretheyproducing?Whattypeofshort-chainfattyacid?Aretheyproducingtoomuchbutyrate?Aretheynotproducingenoughbutyrate?Aretheyproducingcertainchemicals?"Thesechemicalsarebasicallythesignalingmechanismthatgetabsorbedinthebloodandtheycommunicatewiththerestofthebody?Let'scallourselvesthehost.Wearehostandthey'reourguests.Ourguestsareconstantlycommunicatingintermsofwhattheyareseeing.Ifyoulookatthehumanbody,tosomeextent,wearelikea
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donut.Wehavethistubethatgoesthroughus.70%ofourimmunesystemisrightaroundthegut.Asweareeatingfood,ourmicrobiomeisanalyzingitandactuallycommunicatingwithourimmunesystem,"Isitafriendorafoe?"It'stellingimmunesystem,"Hey,watchout.I'mgoingtosendyouthesignal,inflamethethingsandstartthekillthesystem.Thisisnogood."Theyareconstantlysymbiotic
relationshipbecausethesemicrobiomewantstokeeptheirplaceinthegut.Anytimetheyseeaparasitethattheybelieveisgoingtotakeovertheirplace,theycallfortheairhelpandsay,"Help,help,sendtheairpower.Sendtheimmunesystem.Killthem.Killthem.Enemy,enemy."Mypointistheyworkreallywelltogether.What'sinterestingismanyoftheneurochemicalsthatweknowoftoday,likeserotonin,mostpeopledon'trealize90%oftheserotoninisactuallyproducedinthegut.Ifyouimaginewhathappenswhenwearedepressed,weeat.Thinkabout
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thatforasecond.Wherewe'reanxious,wegetbutterfliesinourstomach.Wedon'tgetthebutterfliesinourhead.Whatdoesyourmothersaywhenyouwereill?"Harry,listentoyourgut.Doyourgutcheck."Mypointisthisissomethingwehaveknownformany,manyyears.WhatsurprisedmewasactuallyIwasjustgoing
[00:17:40] throughthethingsandHippocratessaid2,000yearsago,"Alldiseasesstartinthegut."Thinkaboutthatforasecond.2,000yearsagohesaid,"Alldiseasesstartinthegut."Hesaid,"Oneman'sfoodisanotherman'spoison."Thinkaboutthat.Whathe'ssayingisthereisnosuchthingasuniversalhealthydiet.Afoodwhichis
amedicine,oneperson'smedicine,isotherperson'spoison.Thatmeansadietthat'sgoodforyoumaynotbegoodforme.Adietthat'sgoodformetodaymaynotbegoodformethreemonthsfromnowbecauseasIchangemydiet,what'shappening?It'schangingmymicrobiome.Thatmeanscommunicationisnowchangingandbodyisnowadaptingtoonesetofthings.Whenwe'reeatingonesetofdiet,it'sonlyfeedingonesetofmicrobiomeandit'sstarvingtheothersetofmicrobiome.Guesswhat'shappening.Thatcommunicationisgettingweakerandweakernow.Thatmeansourbodyisoutofbalance.Ifthebodyisoutofbalanceagain,you'regoingtohaveimbalance,uneaseanddisease.Ideaistokeepthiscommunicationofallthemicrobialecosysteminitselfcommunicatingwellincommunicationwiththehostandkeepingeverythinginbalance.
Harry:
BecausethemicrobiomeisbasicallycreatingadiseaseorcreatinghealthandIguess,fromyourviewpoint,youcanchangethemicrobiomeandchangetheoutcome,buthowdoyouknowwhethertoimprovethemicrobiomethatyouhavenowbecausethatmicrobiomemightbesuitedforyouortotryandchangethemicrobiomeforafutureoutcome?
Naveen:
Actually,it'snotassimpleaschangethemicrobiome,changethehealth.Itreallyisaholisticsystemthinginasensethateverythingwedoimpactseachother.Thatmeanstheplaceswelive,thetoxinsweinhale,theGMOfoodweeatandallofthepesticideswe'reeating,that'schangingthemicrobiome,that'schangingthedisease.Ourstressinourbody,thatisnothingtodowithmicrobiome.Stressiscausedbecauseweareunhappyatwork.We'reunhappyinourrelationship.Thatstressthecortisolreleasesnotonlychangesourbody,ourgeneexpression,italsochangesthemicrobiome.Whenyouchangethemicrobiome,itchangesthebody’s
geneexpression.Sometimesourgeneexpressionchangesourmicrobiome.It'sbasicallyabidirectionalcommunication.Itisnotsimplyaunidirectionalcommunicationthatsaysyouchangeyourmicrobiomeandthat'sreallywhereeverythingemanatesfrom.Everythingimpactseverything,andwhatwearetryingtodoistoreallykeepallthesethingsworkingwelltogether,findingwherevertheweakestlinksare,fixingthatweaklink.Sometimesit'sinthecommunication.Sometimesit'sthenothavingthemechanismtocommunicate.Thatmeanstheorganismthatneedtobeproducingcertainenzymesdon'texist.Thatmeanswe
havetogiveyouthoseenzymesartificiallyuntilwecanbuildthat.Forexample,ifyoudon'thaveenoughCoQ10,thentherearecertainATPcyclethatjustnotgoingtobecompleted,sowe'regoingtosay,"YouneedtotakeCoQ10.Youneedtotakemagnesium,"or,"Youreallyneedzinc,"or,"Youreallyneedbutyratebecauseyourmicrobiomeisnotproducingenoughbutyraterightnow."
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Whatwedoisnotjusttellyouwhatisgoingoninsideyourbody,weveryspecificallytellyouthatyouneedthesemicronutrientsandyouneedthesemacronutrients.Formepersonallythatwasverycounterintuitive.Iwastryingtoloseweightandeveryonetoldme...Iwasprediabetic.Everyonesaid,"Oh,that'sreallyeasy.Youreallyneedtogoonano-carbdiet.Ifyoucutdownallthecarbsandyoustarteating..."
Harry: Anditmadeyoufatter,right?
Naveen: Itdidmakemefatter!
Harry: Ihadthesamething.IdidtheketogenicthingandIstartedgoingdiabetic.Afterninemonthsofit,Imeasuredbybloodsugar.Thiswaslastyear,andIwent,"Yeah,I'mgoingdiabetic."Anyway.
Naveen:
That'sexactlywhathappenedtome.TheinterestingthingisthenIlaunchedtheViomecompanyandIdidmytestanditsaid,"No,morethan50%ofyourdietreallyneedstobethecomplexcarbohydrateandbytheway,stopeatingtoomuchspinachandavocado.Don'teatlentils,legumesandtofu.Starteatingapplesandstarteatingothervegetables,starteatingotherfruits,butdon'teatavocadoandspinach."Thatwasthatpersonalized.InterestingisnotonlynowIlostmorethan
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fivepounds,mybloodglucoselevelhascomedownsignificantly.Mypointisthisissocounterintuitiveandthesefaddietsaretheonesthatreallyarekillingpeople.RemembertheAtkin'sdiet,thepoorAtkin'sdiedofheartdisease.Thenwewentonapaleodietandnowthisfaddietcalledketogenicdiet.Thenyougointothelactindiet.Everyfewyears,there'sanotherfad.
Harry: Yes.It'sdietmadness.
Naveen:[00:23:30]
Whatreallyhappensisthereisnosuchthingisuniversalhealthythingasyouweretalkingabout.EachthinghastobepersonalizedformebecauseourDNA.Thinkabout,ourDNAhave99%commonbetweenanytwohumanbeings.Infact,meandatreehave90%samecommonDNA.Whenitcomestoourmicrobiome,itisextremelyunique.Lessthan5%ofourmicrobiomeissamebetweenyouandIbecauseyoumeetdifferentpeople.Whenyoutouchpeople'shand,youhugpeople,theairyouarebreathing,thefoodyouareeating.Everyoneofthosethingschangesyourmicrobiome.Yourmicrobiomeismoreuniquethanourfingerprint.
Harry:
IguessthebitI'mtryingtoworkoutisittherightthingtotryandeatforyourmicrobiomeinthepresentoristhereafuturemicrobiomethatmightbemorehealthyforyouandthereforemaybeyoushouldbeeatingtosomeotherfuturestateofmicrobiome?
Naveen:
Interestingthingisyouhavetointroducethat...Therearetwotypesofconcept.Oneisprebiotic,thathowdoyoufeedtheonesthatyouhaveandyoumayhavesomethingthatareaverysmallquantityandothersareinverylargequantity.Ifyouwanttogrowtheonethatareinthesmallquantity,thenyoucanfeedthe
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rightsetoffoodtofeedthemsotheycanactuallystarttogrow.Ifyoudon'tevenhavetobeginwiththemicroorganism,thenyouhavetointroducethemthroughprobiotic.Itreallyisnotaboutjustfeedingtoyourcurrentmicrobiome.Youhavetofeedtoyourcurrentmicrobiometokeepthebalancegoing.Thatmeansreallymakingsuredoyoureducetheonethataretoomuchandincreasetheonethataretoolittle.Thenyouintroducethenewsetofmicrobiomethroughprobiotic.Thereisnooneprobioticforeachperson.Youhavetofindwhat'slacking.Even
then,youhavetointroducetheideaofthesechemicalsthatarelacking.Thatmeansyoustillhavetokeepthebodyinbalancesothatyoucanstartmovingistogiveyouthezincandthemagnesium.Wedon'tsuggesttakethemultivitaminbecauseyou'repissingitoffbasically.It'stounderstandexactlywhatisneededforthebodyandthatreallyisourkey.Ourkeyistogiveyoutheactionablethingyoucandotodaytokeepyourbodyhealthy.ThemainthingthatIlove,Harry,the
satisfactionIgetisyougotodaytotheFacebookandjusttypeViome.Ourcustomersareourbiggestpromoter.They'realltelling...Weneversaywecureanydiseases,andourcustomersareconstantlytellingeveryoneelse,"Ihadthis,andmyGodIfeelbettertodaythanIhaveeverfeltinlast10years.I'vebeenonthismedicineforfiveyears.I'veneverhadthatmuchsuccessassimplyjusteatingthisViomerecommendation."Weareusingthefoodasamedicinethatamedicinecouldn'tdo.
Harry:
That'swonderful.Let'stalkalittlebitaboutthecommunicationsysteminthebody.Wewerehavinglunchback...IthinkitwaslastAugustatJJ'sMindShare,Ithinkwhereweweretalkingaboutcellularcommunicationandthenyoujustmentionedhowyouthoughtbacteriawereusinganon-localformofcommunication.I'dlovetohearyourthoughtsonthat.
Naveen:
Firstofall,youareoneofthesmartestguyswhoactuallyunderstoodwhatIwastalkingabout.Mostpeoplesay,“Oh,whatever.What'sforlunch?"It'sveryinterestingthatthesecommunicationmechanismsaresomanydifferentwaystheseorganismscommunicateamongthemselvesandtothehost,whichisthehumanbody.Nowweknowthateventhebacteriaarecommunicatingwhattheycallquorumsensing.Quorumsensingisreallythisdecentralizedsystemandthekeyiseachindividualsarereleasingthissignaltosay,"I'mhere.I'mhere.I'mhere."Untiltheygetenoughoftheunitytosay,"Okay,enoughofusareherenow,"theychangetheirbehaviorsuddenly.That’swhentheychangethebehaviorthenstart
releasing.Youknowthebiofilm,themucusythingthatyouseesometimewhenyouare...Youhaveawoundandyouseethismucusthing.That'sactuallythebiofilmandthebiofilmsgetformedwhenthesebacteriastarttosensethere'senoughofthemnow.Theycanformarelationshipandcreateabarriersonobodycangetinnow.Thatbarriertheycreatetoprotectthemselves.Oncetheycreateabiofilm,itgetsvery,verydifficulttopenetrate.Bytheway,it’snotjustthebacteria.
Mostpeoplethinkthatmicrobiomeisaboutbacteria.Interestingthingissomethingcalledmycobiomeisthefungalcommunity.Thefungalcommunityisactuallyjustasimportantinsidethegutbecausethisallcommunicateswitheachother.Theyeast,moldandespeciallythevirusesandmorethantheviruses,thebacteriophages.Bacteriophagesarethevirusesthatonlyimpactthebacteria.
Allthisecosystemisnotsomethingisgoodorsomethingisbadperse.They
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becomegoodorbaddependingonwhatelseisthere.Inasense,theycankeepeachotherincheckandyouneedallofthemforthisgoodecosystem.ThinkofitlikeanAmazonianforest.It'snotonethingisgoodorbad.Youtakeonethingout,everythingelsechangesbecausepeoplearefeedingoneachother.Ifyoutakeonethingout,there'ssomethingelsewho'snotgettingfedandtheyreduceandeverythingelsechanges.They’realsousingelectricalsignallikeneuronsto
communicatewitheachother.Theyusethechemicalsignalsthatgetabsorbedfromtheguttothebloodandtheycommunicatewithourmitochondria,which,bytheway,usedtobetheancientbacteriathat'scapturedbythehumancellandithasownDNA.TheymodifyourmicroRNAanditchangesthegeneexpressionofwhoweare.Wearenotourgenes.Weareourgeneexpressed.Whatgenesare
expressediswhatmakesuswhoweare,notthegeneswehavebecausegeneswehaveislikealphabet.Wecanwriteathrillerwiththatorwecanwriteapoetrywiththat.Whatisbeingwritteniswhatreallymatters.
Harry:
It'ssofascinatingthenetworkofhowthingscommunicateinthebody.HowwouldIputit?DoyouseeIguessthedifferentcellshavedifferentenergystatessothey'reallcommunicatingatdifferentlevels?
Naveen:
Yes,tosomeextent.Oneofthethingsthat'sreallypuzzlingtomethatIintuitivelybelievedwasthere,butneverwasanysignofitwhichwasthateventhebacteriainthegutareusingtheelectricalsignaltocommunicatewitheachotherverysimilartoneurons.You'restartingtoreallygetthispicturethatweashumansarereallyusingmanyoftheoriginalmechanismsthatwereevolvedasbacterialorganisms.Ifyoulookathowbacteriascommunicatewitheachother,we'restartingtodevelopourbrainsthatcommunicateusingthesamething.Youlookatourenergycellthat
themitochondria...Mitochondriausedtobeanancientbacteriathatwascapturedbythehumancell,soifyouthinkaboutit,ithaditsownDNAseparatefromthehumanDNAandit'sperformingataskinsymbiosiswiththehuman,ourcell.Then
howmicrobiomeiscommunicatingwithmitochondriaandhowmicrobiomeisinterferinginthegeneexpression?Tosomeextent,weweretalkingaboutthattolargeextentthemicrobiomeiscontrollingmanyofthethingsthatarehappeninginthebodyandtheretolargeextentyouwouldthinkofthemasacentralizedcontrolsystemoryoucouldcalltheminasimplerwordpuppetmasters,andthey'repullingthestringsandthepuppet,ourbodies,say,"Okayboss.Okayboss.I'mthere."
Harry:
Whatmakesyouthinkit'samicrobiomethat'sthecontrolsystemIguessversusthananoverallfieldcontrolsystem?It'slikethere'sthatconceptinphysicswheneverythingisholographic.Youcan'tnecessarilysayAcausesB.It'smoreofasynchronisticevent.
Naveen:[00:32:00]
I'lltellyouwhy.Theydidsomeoftheveryinteresting,whatIwouldcallthecausativestudies.It'sveryinteresting.Therearetwostudiesthatwerereallyinterestingthatisstartingtomakemebelievethatthecontrolsystemisthemicrobiome.Onewastheytookinter-speciestransferofmicrobiome.Theytookthemicethatisbredtohavenomicroorganisminthegut.Theybasicallykilledallthemicroorganism.Thentheytookthemicrobiomefromthefatpersonandgave
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ittothesemice,andthesemicebecamefat.Thenthetookthemicrobiomeofthethinpersonandgaveittothemiceandthemicebecamethin.Thatstarttoshowthecausativethingwasreallythismicrobiome,nottheholisticsystem.
Harry:
I'mgoingtochallengeyouonthat.Doyouthinkthat'sreally...Anythingcanbroadcastinflammation,soifyoutakethemicrobiomeandit'sgotthatsetofinflammationbecauseit'sbeenusedtobeingfat,thenit'llbroadcastfat.Inparallel...Ithinkyou'llfinditquiteinteresting.We'vebasicallybeenstudyingwhatwecallinformationmedicine,wherewe'rebasicallyabletoputinformationontoasignalandthenthatinformationistransferredtowhatwewouldcalltheBody-Fieldthat'sthenpickedupbyeverycellinthebody.
Naveen:
Ithinkisreallywhat'shappeningisthesemicrobiomearereleasingtheinflammationsignalandtheinflammationsignalisintheformofthesemetabolites,whicharereallythesesmallmoleculeswhicharegettingabsorbedinthebloodandthatareessentiallysayingthesignaltothethings,"Hey,startenlargingthesefatcellsbecausethefamineiscoming."
Harry: Yeah,Ilovethat.Ilovethat.IguesswhatI'msayingisthere'sotherwaysyoucanimprintortransmitinformationtothebodybecauseyoucandoitthroughtechnology,etc,aswell.
Naveen:
That'sabsolutelycorrect.Youcouldpotentiallywouldhaveremovedthemicrobiomeandtakentheinformationthatmicrobiomesarecommunicatingthroughothermechanismanddeliverthesesameresults.Forexample,whenyoutakemetformin...Metforminisadiabetesdrug.Thatactuallydoesnotworkonthehost.Itactuallyworksonthemicrobiomeandallowsthemicrobiomeinformationtochange.Thatinturnchangestheinsulinresistance.Mypointisultimatelyall
we'redoingischangingtheinformationsignalthatarecomingoutofmicrobiomeandbychangingthatinformationsignal,ourbodyreactsdifferently.ThattomeisreallythekeythatwearethisholisticsystemandourWesternmedicineisdesignedasthesecomponentsandthemorespecializedyoubecome,youlookatthecomponentssay,"AslongasIcanmakethesecomponentworkoptimally,everythingelseshouldwork."However,youdon'trealizetomakethissystemworkoptimallyandatpeakperformance,thenyoufindaweakpointsomewhereelseandthesystemalwaysbreaksattheweakestpoint.
Harry:
Gotyou.Haveyouread...There'sanarticleinNewScientist...Goodnessme,Ithinkitwasabouttwoorthreeyearsago...Ofallofthisbacteriathatwasdiscoveredinthesoilthatjustlivedoffpureelectrons.Itdidn'teatfood.Itwasn'tdigestinganythingsolid.Itwasjustlivingoffrawelectrons.
Naveen:
It'sveryinteresting.Wefindthebacterialorganismthatarethrivingintheradioactivenuclearwaste.Thinkforthatforasecond,notonlythatnaturehasfiguredouthowtoprotectitsDNAfromthehighradiation.Sowhenpeoplesayhowcanhumansliveinthisspacebecausethereissuchahighradiation,theydon'trealizethatnaturehasalreadybuiltinthemechanismthatusesthemechanismsothatnotonlywecanprotectourDNA.Itusestheradiationatasourceofenergy,so
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itdoesn'tneedanymorefood.Itusestheradiationasasourceofenergytothriveandreplicate.Nowimagineifyoucantakethegenesfromthatbacteriaandwewill
usethecrispertechnologytomodifythehumangenesandsuddenlynotonlyweareprotectedfromtheradiation,wedon'tneedtoeatpizzaanymore.Wecanjustgowalkandgettheradiation.
Harry:
Ithinkslightlydifferently,butwe'vealreadygotthatgeneinasense.GilbertLing,Ithinkitwasinthe'60s,hewrotethispaperwherehewasbasicallycalculatingthesourceofenergyinthecell.Hecalculatedthatonly25%ofitwascomingfromthefatandcarbohydratedowntoATProuteand75%wasbasicallyunaccountedforinthenormalATPcycle.Thenhisexplanationwasit'scomingfromambientheatandalittlebitlikephotosynthesisandheat'sbeingconvertedtoasourceofelectronsinthecell.
Naveen:[00:37:40]
Thatisafascinating,fascinatingwork.Ihavetoreadonthatbecausethatreallyisveryfascinating.TheotherthingthatIfindreallyfascinatingisthathowourgutandourbrainareactuallyconnectedthroughthevagusnerveandweareconstantlycommunicatingbackandforth.It'sabidirectionalcommunicationsystem.We'reusingthecortisol,theserotoninanddopamineasthereaction.That'swhyyouwouldnoticethatwhenyou'reanxious,yougetthebutterfliesinthestomach,alltheserotoninthat'sproducedinthegut.Ourvagasnerveisthat
thecommunicationmechanismandtolargeextentourbehaviorisdeterminedbyourmicrobiome.WhatIfindreallyfascinatingisthatwhenwearefullisdeterminedbyourmicrobiome,whenwearehungryandwhatwecraveisactuallydetermined.Iwonderthattolargeextenttheyaretheonethat'spullingthesestrings.Inoticeabidirectionalcommunicationmechanism,buttolargeextent,there'ssomuchofthemandthere'ssomanygenesthatthey'rebeingexpressedtherethattheyhavealotofimpactonwhathappensinthehumanbodyandsometimesIwonderarewereallylookingatthisthinginawrongway?You
remember,longtimeago,weusedtobelievetheEarthisthecenterofoursolarsystemandwhenGaleleosaysthatitmaybetheSun,theywantedtokillhimbecausehewasfundamentallychangingthatwearenotthecenter.Whatifwearewrongandwebelieveourprimarybrainishereandthisourgut,wecallasecondarybrain?Whatifthatwastheprimarybrain?Whatifourgutwasourprimarybrainandthethingsittingonthetopofourshoulderissimplythemotorcortexthatfollowsthedirectionof…
Harry:
I'llgoonefurtherthanthat.Whatdoyouthinkifit'sevenoutsidethephysicaltissueperseandit'sactuallyinafield?Likeinmedicine,there'sMRIs,EKGs,ECGs.Weknowthesefieldsexistandwejustthinkthey'reinterestingfromadiagnosticpointofview,butit'salsopossiblethatthereverseistrue.IfyoutaketheEinsteinquote,"Ifthefieldisthesolegoverningforceoftheparticle.”Perhapsactuallyitcomesfromoutsideandit'sreallytheenvironmentthat'sdictatingyou.
Naveen:
Theanswerisabsolutelytrue.There'sjustnodoubtinmymindthatwecannotliveinisolation.Everythingaroundus,themicrowave,theWiFisignal,theEMFthatisbeing...Everyoneofthosethingsareimpactingourbodybecauseanytimeyouhaveenergyarounduswhichisnowespeciallyinthiselectronicage.Remember,
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we'resleepingwithourcellphones,wearebathedwithaWiFisignal.Ifanybodybelievesthatnoneofit'sgoingtohavinganyimpactonthehumanbody,thatiscompletelywrong.Wejustknowthatwhenyouimpacttheenergyaroundus,isgoingtoimpact...Ourtissueisgoingtochangethechemicalreactionandeverythingchanges.Youthinkaboutwhatmicrowavedoes.Howdoesmicrowave
heatthefood?It'sessentiallychangingandisspinningthethingsandthey'rechangingthethermodynamicsofthething.Howcanyoupossiblybelievethatit'snotchangingthechemicalpartofwhatyou'reheating?That'showtheheatingworks?Sobelieve...Mypointisyou'reabsolutelycorrect.Everythingarounduschangeswhoweare.I'mnottryingtogettingintothevoodoostuff,butthefactistheenergyarounduschanges.Eachoneofusareemanatingtheenergyandwe
areabsorbingtheenergy.Whenyouseethetwopeopleinteractingandthephysicalproximityofeachother,therearealotoftimeswecanfeelthatenergyandwefeel...Sometimes,wesay,"Wow,Ilikethisperson.Itfeelsgoodorpositiveenergy,"andsometimesit's,"OhmyGod,hejustgivesmebadvibes."Whatisthatbadvibes?Itisussensingthatenergyandwe'resaying,"It'snotintunewithourreceiver.Thetransmitterisn'tcompletelyoutoftunewithourreceiver.He'snotmytype."That'sonething,andyoucouldalsoargue...Ididn'twanttogohere.
Harry: Sorry,I'mmakingyouuncomfortable.It'sgood.
Naveen:[00:42:00]
Coulditbethatweashumanbodydoesn'treallyexist?Itonlygetscreatedthroughourimaginationthatwearethere.Thatmeanswhatifthehandthatweseeisnotthere.OnlywhenIlookatit'stherebecausewhenIdon'tlookatit,Idon'tseeit,right?WhenItouchit,isitsimplythehapticfeedbackthatI'mgettingthatifsomethingisthere,it'sverysimilartowhatifyouwerewearingafullbodysuitinavirtualrealityandyoucantouchsomethingandyoufeelit'sthereeventhoughit'snotthere?Whatisourbrainisplayingthevirtualrealitygameandthatweare
seeingthingsthatdon'tquiteexistandwe'regettingthehapticfeedbackthat'sbuiltintooursomatosensorysignalsthatwegetfromthetouch?Whatifthattouchisactuallybeingfabricated?
Harry: Whenyoulookinto...Iguessintophysics,thephysicsofrealityIguessisquitesimilartothatMatrixideaofsimulationbecauseultimatelythere'snothingthere.
Naveen:
It'sveryinterestingthatthereisveryfewtimesthereligionandthesciencearesayingthesamething,butinadifferentword.YoulookatthescientistorevenElon.Elonbelievesthatweareliving...Thechancesofusnotlivinginavirtualrealityareclosetozero.Hebelievesthereisaprogrammerwhocreatedthiswholethingcalledhumanityandwearesimplyavatarsinsomebody'svirtualgame.Thatmeansaprogrammercreatedus.ThereligionsaysGodcreatedus.WhatiftheGodistheprogrammer?Mypointiswe’resayingthesamething.Inareligion,wecall
thataGodandthesciencecalledusaprogrammer.Wecalledthatacreator.Isn'tthatthesameconcept?Basically,everyoneissayingthatwearelivinginthisvirtualworldandwedon'treallyquiteexist.MaybetheBigBangwasnothingbutaMacrebooting.
Harry:
Ithinkwhatthatdoesdoisitgivestremendouspowertotheindividualovertheir
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healthbecause,asIsay,it'snotjustfromtheenvironment.Yourthoughtisprobablythemostdirectformofcontrolsystemthatyoucanguess,andthatcanobviouslyaffectallofyourhealth.
Naveen: IwouldliketocomebacktoViome.
Harry: I'msorry.Iknow.I'msorry.Naveen:[00:45:00]
Havinggonethroughallofthethings,let'sbringitbacktothereality.Harry,whatdidyouunderstandisthatwhatViomedoes?Iwantyoutoexplainthistome.
Harry: Okay,sure.Basically,whatViomedoes,fromapractical...Let'sjusttakepeoplethroughthepracticalside.Basically,theycangotoyourwebsite.Theycan…
Naveen: What'sthewebsite?Harry:
Itisviome.comhopefully.
Naveen: Yes,itis.
Harry: That'sgood.Theycangotoyourwebsite.Theycanorderamicrobiometestandthenfromthattest,theysendyoubackasample.
Naveen:
Actually,it'snotamicrobiometest.Thisisreallyathingwesendthatdoesboththemetabolicintelligenceandthegutintelligence.Welookathowdoesyourbodydigestthecarbohydrate?Howdoesyourbodydigestproteinandfat?That'slookingatthehostsidebylookingattheblood.Thenwelookatwhat'shappeninginsideyourgut.Thenwe'readdingcoupleofmoreteststhataregoingtobecomingoutinthenext60to90days,whicharearoundthemitochondrialgeneexpressionandthebloodgeneexpressionandtheinflammationandlookingattheurinemetabolites,whichessentiallyshowsyouthebiochemicalreactionsofthebody.Wetakeallthisdataandthenweputthatintotheartificialintelligence
enginetoseewhatisgoingoninsideHarry'sbody?Whatistherightnutrientsthatheneeds?Whatishelacking?Thenwemakeveryspecificrecommendationonwhatfoodyouneedandwhatsupplementsyouneed,whatprobioticsyoumayneed.Again,we'renotsellinganyofthestuff.Ourjobistosimplytellyouwhatyourbody'slackingratherthantrytosellyouanything.Wesay,"Look,hereiswhatyouneedandyoucangobuythemfromAmazon.Youcanbuythemfrom...Herearethethreevendorsthatwelike."Thepointisourjobistoliterallybeonyour
sidetoempoweryouwithinformationandgiveyoutheactionsyoucantakebecausewewantyoutobelieve.Youdon'tneedadoctorsimplylookingatthething.Bythetimeyouwalkin,he'salreadywritingaprescription.Theydon'twanttohearyourstory.Theydon'tevenwanttoknowwhat'sgoingon."Ohdoc,myheadhasbeenhurting.""Oh,yougotabraintumor.""No,no,doc.I'vebeencoughing.""Oh,yougotpneumonia.""Doc,listentomeforasecond."Mypointisthey'resimplytryingtofindoutdrugtoprescribeyou.That'sallthey'rethinkingabout.They'renotthinkingaboutwhat'swrongwithyou?HowdoIfixit?They'renotlookingatthestuffandsaying,"Whyisthebodybeinginflamed?Whyisthe
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communicationbetweenthesecellsarebroken?"Everysingledrugthatyoutake
actuallyfixesonesymptomandcausesthreemoresymptom.Surprise,theyhaveadrugforeachsymptom.Tome,onceyougetintothat,youliterallyareatthemercyofthesepharmaceuticalcompanieswhodon'thaveyourbestinterestsatheart.Whatwe'redoingreallyatViomeisgivingyouthatcontrol.Ourhopenowinallseriousnessreallyis...Forme,thisismymissionbecauseIfeelthatGodhasbeenverykindtous.Icametothiscountrywithabsolutelynothing.Societyhas
givenmesomuch.Godhasgivenmesomuch.Tome,mymissionistohelpthebillionsofpeopleremovetheirsufferingfromallthesechronicdiseases.Ireallybelievethisisthefirsttimeinthehumanhistorywhereweactuallyhaveapowertobeabletounderstandwhatisgoingoninsideourbodyandkeepthatthingsimplyusingthefood.Wedon'treallyneedtopharmaceuticaldrugs.Ifwedoour
jobright,onedaysicknesswillbeoptional.Ijustneedyourhelpandeveryonewho'slisteningtoittoreallysignupandunderstandforthemselveswhatisgoingon,buteverypersonwhosignsupalsonotonlyhelpsthemselves.Italsohelpsthehumanitybecausemorepeoplecometogether,moreinformationwehave.Themoreinformationwehave,ourartificialenginejustkeepsgettingbetterandbetterbecauseitjustneedsmoredataandmoredata.Everypersonhelpsthemselvesandhelpseveryonebeforeandeveryoneafter.Tome,itisourdutytocometogether
totakethecontrolofourownhealth.Ifwedon'tdoit,Iwillgetfrustratedandgooutanddosomethingelseandtheproblemwillcontinuetoremainthesameandthehealthcaresystemwillcontinuetovictimizeus.Ihopeeveryonewho'slisteningtoitwilljoinusinthisrevolutionandtrytotakecontrolofourownbodyandourownhealth.
Harry:[00:49:30]
Couldyoutellusalittlebitmoreabouthowartificial...Well,basicallyhowyou'reusingartificialintelligencetoreallyhelpsolveit?
Naveen:
Basically,ifyouthinkaboutit,youstarttolookat...Wedon'tcomeupwiththehypothesisthatsays,"Thiscausesthis,"becausetheproblemthathappensisintheolddays,thescientist'sideawasyoucreateahypothesisandthenyoufindtheempiricalevidencetoproveordisprovethathypothesis.Intheworldofmassivedata,whathappensyouhaveahypothesisisyoucanfindthepatterninthenoise.Ifyousay,"Thiscausesthisandifboththingsexist,thenweknowthisdiseaseis...Thisisthecause."What’shappeningiswhenyouhavepetabytesofdata,youcan
findanyhypothesisyouwant,andyoucanproveanythingyouwant.Whatwedoisactuallyslightlydifferent.Wetakeallthedatasowegetalotofthesymptomaticinformationthatwhenpersongetsonboarded,they'retellingusallthethingsthataregoingon.Ifwelookatallofthemicrobialdatathatmeanseveryorganismthat'sthere,howactivetheyare,whatthey'reactuallyproducing.Welookatallthemacronutrients,informationfromthemetabolicsite.Aswe’regettingmore
informationfromgeneexpression,we'relookingatallthatstuff.Thenwesayit,"Whatiscommon?Whatistheclustering?"We'vegonethroughtensofthousandsofalgorithmandthenwestarttofindthesegroupofpeoplethatareclusteredhere,thegroupofpeoplethatareclusteredhere,thegroupofpeoplethatareclusteredhereandthenwesay,"Wow,lookatthesethings.Theyalwaysseemtobetiedtogetherthesethousandpeople.Whatissouniqueaboutthem?"Thenyou
say,"Wow,noticethat.Theyallhavediabetes.OhmyGod,andlookatthem.They
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allhavelackofbutyrateproduction.Hmm,Iwonderifthat'sreallywhat'sgoingon."Thenwesayifthatisthehypothesis,canwerunandseethenext1,000peopleandseeifwecanprovethat?"
Harry: Perfect.Thisisapersonalquestion.Whenyou'reonstageatMindShare,IthinkyousaidtoJJyoucouldteachhertohaveotherpeoplerunhercompaniesforher,butyoudidn'texplainanyfurther.Iwasjustcuriousonthat.
Naveen:
It'sveryinterestingisthatIfindthatonceyoubecomeanexpertinwhateveryou'redoing,you'reonlyabletoimproveitincrementallyby5%,10%,15%.Youcanmakeitbetterbecauseyou'reexpertatit.Ifyouwanttochangesomething10timesor100times,youhavetocomefromoutsidetheexpertisebecausetobecomeanexpert,youhavetoessentiallyhavethefoundationalknowledgeandyoucanneverchallengethatfoundationalknowledgebecauseyou'renolongeranexpertthen.Whenthenon-expertcomesin,theystarttochallengethefoundationofeverythingthatpeoplehavetakenitforgranted.Iamnotadoctor.Iamnota
scientist.Icamefromthefundamentalbeliefthatyoucan'thaveallthesedifferentdiseasesandhavethesedifferentdrugsandworksforeverybodyinthehumanitywhenweknowwearesounique.Therehastobesomethingelse.WhenIstarteddiggingthroughalltheresearch,itbecamecleartomethesystemhasbeenignoringthemicrobiome.Thereasontheyhavebeenignoringisbecausetheywanttohavemassproduceddrugsthatcanbesellingtobillionsofpeopleandtheydon'twanttopersonalizeit.Isaid,“Whatiswecanpersonalizeit?Whatifwedon’t
reallyneedthedrug?Whatifthefoodwastheonlymedicineweneed?"Thatfundamentalbeliefiswhatcausedmetostartbuildingateam.Thinkaboutit.TheheadoftheIBMWatsonResearchcameandjoinedmebecausetheywanttosolvethisproblem.Itisthelegacy.Itissomethingthatcanhelpabillionpeople.Dr.Messier,Dr.Perlina,youlookatDr.Banavar,Dr.Vuyisich.Allthesepeoplecametogetherbecausetheyallwerealignedtothismissionofmakingsicknessoptional.Mythinkingisthatifyouhavean
audaciousmoonshot,thehumanitywillcometogethertosolveit.Ifyousimplydosomethingtomakemoney,peoplewalkawayfromitbecausepeopledon'twanttomakemoremoney.Peoplewanttodowhat'sreallygoodanddoinggoodanddoingwellshouldbecomingtogetherandthereshouldbenothingthatsimplydoeswellorsimplydoesgood.Ifyouwanttodosmallgoodintheworld,youstartanonprofit.Ifyouwanttodoalargegoodintheworld,youstartforprofit.
Harry: Tosumup,withwhatyoudowithyourtime,areyoumostlyfocusingonthewhyandthewhocanhelpachievetheWhy?Isitassimpleasthat?
Naveen:
Istartwiththewhy.WhatisitthatIwanttodo?IfIdosucceedindoingwhatI'mdoing,howwouldthatchangethetrajectoryofhowhumanity'sgoingtoliveinthefuture?IfIdosucceed,GodforbidI'msuccessful.Woulditactuallyhelpthebillionpeopleacrosstheworld?Iftheanswerisyes,I'mwillingtodedicatemylifetodoingit.That'sthereasonIstartedMoonExpresstoreallysavethehumanityfrompotentialextinctionbecausewe'realllivinginthissinglespacecraftandwedon'twanttobecomeadinosaurifwegethitbyalargeasteroid.IstartedViomeforsimplereasonbecausewecanmakesicknessasanoption,notjustamatterofbad
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luck.Whatifitwasreallyachoicethatyoucouldmake?Myhopeisthatassoonas
Ifinishthis,I'mgoingtogooutandfixtheeducationnext,createabundanceoffood,createabundanceofenergy,createabundanceoflandbecausethereisnoreasonweshouldnotbeabletohaveabundanceofeverything.Whatifenergywasthenextair?Thateveryonehasit,it'sdemocratizedandit'sdemonetized?Thatmeansit'sfreetoanyoneandnoonefightsoverairandoxygen.Whatiftheenergywasthenextoxygenthat'sfreeforeveryone?Ifwehavefreeenergy,wecanhavefreefreshwaterbecauseeventhedirtiestwater,youcanboilanddistill.Pointisifyoucandothat,youcansolvesomanyproblems.Myjobistomoveawayfromthemindsetofscarcityandmoveintothemindsetofabundance.Ifwecandothat,wecanchangehumanity.
Harry:
Iwascurious.Obviously,it'sanextraordinarycareerandvision.Iwascuriouswhat'sunderneathonthat.Lookingatyoubeingabletogofromindustrytoindustryandyou'vebeenthroughawfullotofchange.Alotofpeoplegetreally...Theygetstuckanduncomfortablewithchange.IsitbecauseofyourchildhoodormovingfromIndiatotheStatesIguessthatyou'reabletobeunattachedingreatperiodsofchangesothatyoucanmakerealimpact?Iwascuriouswhat'sunderneathallthis.
Naveen:
Ithinkit'sreallytheintellectualcuriosity.Ireallybelievewhatdrivesmeisthatintellectualcuriosity.Ireadalot.Tome,becauseI'mjustdrivenbywhy?Whyisitworkingthisway?Whycan'titbesomethingdifferent?TherearetimesIwouldspendprobablyreadinghundredsofscientificpapersandthenit'sabookofwhatcauseabodytohaveacancer?Ispentthreeyearsjustlearningabouthumanbrain.Whatisitthat'sgoingoninsidethisbrainthathowitworks?ThenI’llspendthe
timeongeneticsandtheepigeneticsandthemicrobiome.Ijustgodeepintotheseresearchesbecauseit'sjustintellectualcuriosity.WhathappensiseverytimeIreadsomething,I'mcollectingthedots.AnytimeIseetheseproblems,I'mthinking,"Wow,Ihavethismissingdot.IfIcanpluginthere,thatcansolvethatproblem."I'malwayslookingforwhatarethebiggestsocietalchallengesandwhatarethedotsavailableinmypocketthatIcanmixandmatchtosolveaparticularproblem.
Harry: Thankyou.Isthereanythingmorethatyou'dliketosaytotheaudience?Thatstatementprobablysumsitup.
Naveen:
Ireallythinkthatasopposedtolookingattheworldasis,focusonwhatyouwanttheworldtobe.Don'tfocusonisthisglasshalfemptyorhalffull.Focusondoyouwanttofillthisglass?Isthisglassworthfilling?Asopposedtoreallythinkingabouttakingyourkidstothewaterormakingthemdrink?Findaboutmakingthemcurious.Ifyoucanmakethemintellectuallycurious,you'recreatingathirst.Ifyoucanmakethemthirsty,theywillfindthewaterforrestoftheirlifeandtheywillbedrinkingontheirown.Ourjobasasocietyistomakeeveryonethirstyandthethirstcomefromintellectualcuriosity.Thattomeishowwe'regoingtochangethehumanitybycreatinganamazinglyintellectualcurioussociety.
Harry: I'msurefromthateveryonehasgotextremelythirsty.Ireallyhighlyrecommendthattheygotoviome.comandtakeitfromthere.
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Naveen: ThanksalotHarry.Lookforwardtotalkingtoyoumore.Takecare.
Harry: Thankyou.
Wendy:
Pleasekeepinmindthatthispodcastisnotintendedtodiagnoseortreatanydiseaseorhealthcondition,andisnotasubstituteforprofessional,medicaladvice.Pleaseseekamedicalpractitionerbeforeengaginginanythingthatwesuggesttodayontheshow.
