Study Design Clinical Highlights - Boston Scientific...Presented at EuroPCR 2019 by R. A. Kotronias....
Transcript of Study Design Clinical Highlights - Boston Scientific...Presented at EuroPCR 2019 by R. A. Kotronias....
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Length of Stay with ACURATE neo vs. Evolut™ R
ACURATE neo Aortic Valve System – Clinical Data
Clinical Highlights
Study Design
Routine use of the ACURATE neo self-expanding valve is associated with improved procedural outcomes and reduced post-operative length of stay: Insights from a single-center registry (ACURATE neo vs. Evolut R)
Kotronias RA, Banning AP, Kharbanda RK. Oxford University Hospital. Presented at EuroPCR 2019 by R. A. Kotronias.
Single-center study from Oxford, Great Britain, evaluating the impact of valve selection on procedural outcomes, length of stay (LoS), and 30-day mortality in 231 patients treated with either ACURATE neo (n = 143) or Evolut R (n = 88) between March 2017 and September 2018.
ACURATE neo demonstrates reduced post-operative complications and permanent pacemaker rates and comparable mortality and stroke rates vs. Evolut R
Improvements in procedural outcomes with ACURATE neo are associated with reductions in post-operative length of stay A multivariate linear regression model identified peri-procedural complications, pre-existing RBBB, and new permanent pacemaker implantation as independent predictors of post-operative length of stay.
3 3 32 2
In-hospital mortality
30-day mortality
0
Stroke
10
29
8 9
New PPI after TAVI
1 1
Life- threatening
bleeding
Major vascular
complications
ACURATE neo (n = 143) Evolut R (n = 88)
ACURATE neo
0
1
2
3
4
5
6
7
8
9
10
Evolut R
Post-Operative Length of StayProcedural Outcomes
Leng
th o
f sta
y (d
ays)
% o
f pat
ient
s
aOR 0.16 (0.05–0.5)
aOR 0.14 (0.01–0.68)
aOR 0.14 (0.03–0.68)
30
35
20
25
15
10
5
0
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