STRONG ANTIBACTERIAL - Hauzer Techno Coating · infections. Coatings with antibacterial effect...

2
Anywhere crowds of people gather, touch-based contamination contributes to the spread of bacterial infections. Coatings with antibacterial effect could have an important public health benefit: think of door handles, bathroom taps and other high-touch elements in schools, hospitals, airports and even homes. “The new test results for Hauzer’s antibacterial coatings are excellent,” says Huub Vercoulen, Deco Sales Manager. “Some eliminated all applied bacteria even after a single hour. We are now looking for customers interested in jointly developing an antibacterial coating for their specific application.” STRONG ANTIBACTERIAL EFFECT IN ENHANCED COATINGS Antibacterial in Rose Gold, Nickel and Black Silver (Ag) and copper (Cu) ions have long been known to have an antibacterial effect. Hauzer R&D developed a coating architecture able to release these ions. The first three enhanced coatings are rose gold, nickel-like and black. These coatings are deposited either by Hauzer Advanced Controlled Arc evaporation (ACA) or unbalanced magnetron sputtering (UBM) and contain Ag or Cu in different concentrations. Gram+ and Gram- Bacteria Bacteria can be classified into Gram positive and Gram negative, based on important differences in their cell walls. Huub: “We previously tested whether Gram- bacteria Escherichia coli could survive for 24 hours on enhanced Hauzer coatings. Now, our testing partners Manchester Metropolitan University (MMU) assessed the antibacterial effect after 1, 3, 8 and 24 hours. They also tested Staphylococcus aureus, which are Gram+ and can exist in antibiotic-resistant form known as MRSA. Together, these bacteria are a good model for unwashed hands, since they live on skin and in faecal matter.” MARKET DEVELOPMENT The testing methodology is based on BS ISO 22196:2011 (Measurement of antibacterial activity on plastics and other non-porous surfaces). MMU researchers inoculated E. coli or S. aureus bacteria onto the coating and sandwiched it with a piece of polyethylene to ensure the cells are evenly spread across the surface. After 0, 1, 3, 8 and 24 hours of incubation, any E. coli or S. aureus that were still alive were recovered from the surface and spread onto agar to grow into bacterial colonies, allowing for the calculation of colony-forming units per ml (CFU/ml). MMU METHODOLOGY TO TEST ANTIBACTERIAL EFFICACY

Transcript of STRONG ANTIBACTERIAL - Hauzer Techno Coating · infections. Coatings with antibacterial effect...

Page 1: STRONG ANTIBACTERIAL - Hauzer Techno Coating · infections. Coatings with antibacterial effect could have an important public health benefit: think of door handles, bathroom taps

Anywhere crowds of people gather, touch-based contamination contributes to the spread of bacterial

infections. Coatings with antibacterial effect could have an important public health benefit: think of door

handles, bathroom taps and other high-touch elements in schools, hospitals, airports and even homes. “The

new test results for Hauzer’s antibacterial coatings are excellent,” says Huub Vercoulen, Deco Sales Manager.

“Some eliminated all applied bacteria even after a single hour. We are now looking for customers

interested in jointly developing an antibacterial coating for their specific application.”

STRONG ANTIBACTERIAL EFFECT IN ENHANCED

COATINGS

Antibacterial in Rose Gold, Nickel and Black

Silver (Ag) and copper (Cu) ions have long been known

to have an antibacterial effect. Hauzer R&D developed a

coating architecture able to release these ions. The first three

enhanced coatings are rose gold, nickel-like and black. These

coatings are deposited either by Hauzer Advanced Controlled

Arc evaporation (ACA) or unbalanced magnetron sputtering

(UBM) and contain Ag or Cu in different concentrations.

Gram+ and Gram- Bacteria

Bacteria can be classified into Gram positive and Gram

negative, based on important differences in their cell walls.

Huub: “We previously tested whether Gram- bacteria

Escherichia coli could survive for 24 hours on enhanced

Hauzer coatings. Now, our testing partners Manchester

Metropolitan University (MMU) assessed the antibacterial

effect after 1, 3, 8 and 24 hours. They also tested

Staphylococcus aureus, which are Gram+ and can exist in

antibiotic-resistant form known as MRSA. Together, these

bacteria are a good model for unwashed hands, since they

live on skin and in faecal matter.”

MARKET DEVELOPMENT

The testing methodology is based on BS ISO 22196:2011 (Measurement

of antibacterial activity on plastics and other non-porous surfaces).

MMU researchers inoculated E. coli or S. aureus bacteria onto the

coating and sandwiched it with a piece of polyethylene to ensure the

cells are evenly spread across the surface. After 0, 1, 3, 8 and 24 hours

of incubation, any E. coli or S. aureus that were still alive were recovered

from the surface and spread onto agar to grow into bacterial colonies,

allowing for the calculation of colony-forming units per ml (CFU/ml).

MMU METHODOLOGY TO TEST ANTIBACTERIAL EFFICACY

Page 2: STRONG ANTIBACTERIAL - Hauzer Techno Coating · infections. Coatings with antibacterial effect could have an important public health benefit: think of door handles, bathroom taps

cfu

/mL

102

101

104

103

105

107

106

E. coli test results

Black (

UBM) +

Ag

Black (

UBM) +

Cu

Nickel (A

CA) - unm

odified

Nickel (A

CA) + A

g 1Nick

el (ACA) +

Ag 2

Uncoat

ed stain

less st

eel

**** **** ** * *

Rose go

ld (ACA) +

Ag

0 1 3 8 24

Time points (hours)cf

u/m

L

102

101

104

103

105

107

106

S. aureus test results

Black (

UBM) +

Ag

Black (

UBM) +

Cu

Rose go

ld (ACA) +

Ag

Nickel (A

CA) - unm

odified

Nickel (A

CA) + A

g 1Nick

el (ACA) +

Ag 2

Uncoat

ed stain

less st

eel

**** **** *

0 1 3 8 24

*

Time points (hours)

Excellent Antibacterial Properties

Compared to an uncoated stainless-steel sample or an

unmodified nickel coating, all enhanced coatings showed

an antibacterial effect. Ivan Kolev, Hauzer Process Manager:

“Both black coatings were extremely effective: 100% kill rate

in only an hour. The rose gold coating eradicated E. coli within

4 to 8 hours and S. aureus within 9 to 24 hours. The Ni-like

coatings showed least efficacy, although still better than the

uncoated or unmodified samples. Nickel coating 1 achieved

full eradication of both bacteria within 9 to 24 hours, whilst

nickel coating 2 managed to decrease the population of

S. aureus by 3 orders of magnitude after 24 hours.” The

performance difference between the two enhanced nickel

coatings is a result of the different level of doping. This

indicates that there is an optimum dopant level.

Depending on the coating type and dopant added, there

can be a marginal colour shift as measured with the L*a*b

colour scale. This can be compensated by readjusting process

parameters.

Seeking Development Partners

With these excellent test results, it is now time to start developing

applications for these antibacterial coatings. Please contact

Huub Vercoulen ([email protected] or +31 6 462 01 462) to

discuss your specifications. Huub: “Are you interested in offering

an antibacterial effect as a selling point for decorative coatings?

Producing door handles or bathroom fixtures that help control

infection? Or coatings for antibacterial jewellery, keyboards

or other innovative products? This market is only just getting

started.”