Stereoselective Synthesis of 2′-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential anti-HCV...

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2007 Nucleic acids U 0700 Stereoselective Synthesis of 2'-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential anti-HCV Agents. — Both compounds (I) exhibit no significant activity against the hepatitis C virus (HCV) in a cell-based HCV replicon assay. — (LEE, J. A.; KIM, H. O.; TOSH, D. K.; MOON, H. R.; KIM, S.; JEONG*, L. S.; Org. Lett. 8 (2006) 22, 5081-5083; Lab. Med. Chem., Coll. Pharm., Ewha Womans Univ., Seoul 120-750, S. Korea; Eng.) — Klein 10- 215

Transcript of Stereoselective Synthesis of 2′-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential anti-HCV...

Page 1: Stereoselective Synthesis of 2′-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential anti-HCV Agents.

2007

Nucleic acidsU 0700 Stereoselective Synthesis of 2'-C-Methyl-cyclopropyl-Fused Carbanucleosides

as Potential anti-HCV Agents. — Both compounds (I) exhibit no significant activity against the hepatitis C virus (HCV) in a cell-based HCV replicon assay. — (LEE, J. A.; KIM, H. O.; TOSH, D. K.; MOON, H. R.; KIM, S.; JEONG*, L. S.; Org. Lett. 8 (2006) 22, 5081-5083; Lab. Med. Chem., Coll. Pharm., Ewha Womans Univ., Seoul 120-750, S. Korea; Eng.) — Klein

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