State of the Biopharmaceutical Industry 2016

State of the

Biopharmaceutical

Industry 2016

Find out what your industry peers are experiencing in the

Biopharmaceutical industry, their views on key issues shaping the sector,

and what topics are of most importance to their business

EXECUTIVE SUMMARY

An overview of the state of the industry and online trends among biopharmaceutical industry professionals

In May 2016, BioPharma-Reporter conducted its inaugural ‘state of the industry’ survey. The key objective of

the poll was to gauge views about the current state of the biopharmaceutical development and

manufacturing industry, its online trends and the issues causing most concern.

BioPharma-Reporter collated over 280 survey responses from biopharmaceutical industry professionals who

form an integral part of the brand’s global readership.

STATE OF THE BIOPHARMACEUTICAL INDUSTRY: KEY FINDINGS

The topics covered in the survey included acquisitions and employment, product development, disposable

technologies, biomanufacturing capacity and key growth drivers & markets.

Sixty-four percent of our survey participants said their company is planning more capital investment

this year versus last year

More than half (62%) of respondents are planning to invest more in new product development

(NPD)

The vast majority (70%) agreed that disposable technologies have become the standard in the

bioprocessing industry

Continuous technologies, disposable technologies and testing & assays were the top three areas in

which respondents think innovation is needed

More than half (55%) believe that there is not enough biomanufacturing capacity

Thirty-seven percent say the industry is currently over reliant on third party manufacturers

Biosimilars was considered as the top key growth driver for firms over the coming year

Survey participants were asked to select the top three regions they believe are the most important

markets in Biopharmaceuticals/Biomanufacturing today. Results revealed North America, Western

Europe and China at the top of the poll with Russia & CIS and Africa towards the bottom

Regarding the most important growth markets in Biopharmaceuticals/Biomanufacturing, China takes

the top spot (61%), followed by India (50%) and North America (43%) respectively

Please note: all survey percentages have been rounded to the nearest whole number

State of the Biopharmaceutical Industry 2016

BIOPHARMA-REPORTER.COM

ACQUISITIONS AND EMPLOYMENT

Sixty-four percent of respondents said their company is planning more capital investment this year versus

last year while 60% said that they would be taking on more staff in 2016.

Fifty-three percent also stated that their company currently has vacancies in key roles.

11%

15%

16%

18%

19%

42%

45%

44%

32%

45%

29%

19%

24%

25%

17%

8%

9%

5%

13%

1%

11%

13%

12%

12%

18%

My company currently has

vacancies in key roles

My company seeks to recruit on an

international basis when looking

to fill key roles

My company will take on

more staff this year than last year

My company has made key

acquisitions in the past year

My company is planning more capital

investment this year than last year

Strongly Agree Agree Disagree Strongly Disagree Don't Know



PRODUCT DEVELOPMENT

More than half (62%) are planning to invest more in new product development this year and 49% agreed

that their customers seem to be more focused on pricing rather than ground-breaking NPD.

12%

15%

37%

47%

31%

17%

6%

4%

15%

17%

My customers are more focused on

price than ground-breaking NPD

My company plans to invest more in

new product development (NPD)

this year than last year




DISPOSABLE TECHNOLOGIES

The majority of respondents (70%) agreed that disposable technologies have become the standard in the

bioprocessing industry.

Over half (55%) believe that the lack of competition is keeping prices of disposable equipment artificially

high while 61% think that the disposable technology market is controlled by a handful of suppliers.

7%

10%

11%

12%

14%

15%

17%

51%

51%

47%

49%

42%

44%

53%

26%

17%

24%

15%

21%

25%

14%

0%

2%

2%

1%

2%

2%

0%

15%

21%

15%

22%

22%

14%

16%

Industry is fully confident

using disposable technologies

Regulatory agencies fully support

single-use technologies

Vendors and end users are working well

together to develop new technologies

The disposable technology market is

controlled by a handful of suppliers

A lack of competition is keeping prices

of disposable equipment artificially high

Innovation in bioprocessing tech

is driven by the end user

Disposable technologies have become

the standard in the bioprocessing industry




WHERE DO YOU THINK INNOVATION IS NEEDED IN THE BIOMANUFACTURING

TECHNOLOGY SECTOR?

Continuous technologies, disposable technologies and testing & assays were the top three areas in which

respondents think innovation is needed.

Stainless systems were ranked at the bottom of the list receiving only 7% of all votes.

6%

7%

25%

25%

35%

37%

48%

55%

0% 10% 20% 30% 40% 50% 60%

Other

Stainless systems

Cell line services

Upstream processing

Downstream processing

Testing and assays

Disposable technologies

(upstream and down)

Continuous technologies



BIOMANUFACTURING CAPACITY

When asked for opinions on biomanufacturing capacity, more than half (55%) of our survey respondents

think there is not enough while only 9% believe there is too much.

THIRD PARTY MANUFACTURERS

Readers were also asked for their opinion on the industry’s reliance on third-party manufacturers. Thirty-

seven percent say the industry is currently over reliant whereas 38% remain neutral.

55%51%

NOT ENOUGH TOO MUCH NEITHER TOO MUCH

NOR TOO LITTLE

9% 37%

UNDER RELIANT OVER RELIANT NEITHER UNDER OR

OVER RELIANT

38% 37% 25%



WHICH OF THESE DO YOU CONSIDER TO BE KEY GROWTH DRIVERS FOR YOUR FIRM

OVER THE NEXT YEAR?

Biosimilars was considered as the top key growth driver for firms over the coming year. Emerging markets

was voted in at number two whilst Regulatory developments came in at a close third with 34% of the votes.

4%

10%

11%

17%

19%

20%

22%

22%

29%

33%

34%

37%

42%

0% 5% 10% 15% 20% 25% 30% 35% 40% 45%

End user consolidation

Supplier M&A

ADCs

Vaccines

Cell and gene therapies

Strong economic environment

Developed markets

Increased biopharma

outsourced spend

Increased biopharma R&D spending

Monoclonal antibodies

Regulatory developments

Emerging markets

Biosimilars



WHERE ARE THE MOST IMPORTANT MARKETS FOR BIOPHARMACEUTICALS/

BIOMANUFACTURING TODAY?

Survey participants were asked to select the top three regions they believe are the most important markets

in Biopharmaceuticals/Biomanufacturing today. Results revealed North America, Western Europe and China

at the top of the poll with Russia & CIS and Africa towards the bottom.

4%

6%

7%

7%

17%

25%

34%

41%

71%

88%

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

Africa

Russia and CIS

Australasia

South America

SE Asia

India

Japan

China

Western Europe

North America



WHERE ARE THE MOST IMPORTANT GROWTH MARKETS FOR

BIOPHARMACEUTICALS/BIOMANUFACTURING?

This time, readers were asked to select the top three regions they believe are the most important growth

markets in Biopharmaceuticals/Biomanufacturing. China takes the top spot (61%), followed by India (50%)

and North America (43%) respectively.

9%

10%

17%

19%

22%

33%

36%

43%

50%

61%

0% 10% 20% 30% 40% 50% 60% 70%

Australasia

Africa

Russia and CIS

Japan

South America

SE Asia

Western Europe

North America

India

China



ONLINE TRENDS AMONG BIOPHARMACEUTICAL INDUSTRY PROFESSIONALS

The three most important topics of interest amongst biopharmaceutical professionals were

biosimilars, big biopharma and market trends

The majority of respondents (36%) said they visit approximately 5-10 work-related websites in a

given week whilst 23% say they visit more than 10 websites per week

Approximately one third of biopharmaceutical industry professionals (32%) visit BioPharma-

Reporter.com approximately 3-4 times per week, with 4% visiting more than 10 times per week

Results revealed that our respondents often use the Internet to read up on news and trends (82%).

Sixty-three percent use it for competitive intelligence and comparative work while 62% use the

Internet to find products, equipment and/or suppliers

More than half of our survey respondents (64%) use the Internet to promote their own business

Search engines were found as the most valuable resource when conducting research for work-

related information. On the other end of the scale, networking sites such as Facebook and Twitter as

well as blogs were seen as least useful

A vast majority (77%) said they have downloaded information as a result of visiting a website for

work purposes. Seventy-three percent stated they have downloaded a white paper whilst 60% have

directly contacted a supplier.

Over half (57%) of our readers have visited the advertiser’s website after seeing an advertisement

online and 44% said they have forwarded the advertiser’s website on to a colleague

BioPharma-Reporter.com was voted as the top source of information for industry news against a list

of competitors



TOP THREE AREAS OF INTEREST AMONGST BIOPHARMACEUTICAL PROFESSIONALS

As well as being considered as the key driver for growth, the survey also revealed biosimilars as the top area

of interest amongst biopharmaceutical professionals. This was closely followed by big biopharma (47%) and

market trends (46%).

49% 47% 46%

BIOSIMILARS BIG

BIOPHARMA

MARKET TRENDS



OTHER AREAS OF INTEREST AMONGST BIOPHARMACEUTICAL PROFESSIONALS

Other areas of interest also included Single Use technologies, Contract Manufacturing as well as Legal and

regulatory. On the opposite end of the scale, Expression Platforms wasn’t considered by many as a

particularly appealing topic.

9%

10%

16%

19%

20%

20%

24%

24%

26%

27%

30%

30%

31%

31%

35%

35%

35%

0% 5% 10% 15% 20% 25% 30% 35% 40%

Expression Platforms

Other

Viral Clearance

Biochemicals/Raw Materials

Cell Culture Media

Supply Chain

Facility Design/Engineering

Cell & Gene Therapies

Fill/Finish

Clinical development

Separation/Purification

Vaccines

Antibodies

Bioreactors & Fermentation

Legal and regulatory

Contract Manufacturing

Single Use technologies



HOW MANY DIFFERENT WORK-RELATED WEBSITES DO YOU GENERALLY VISIT

IN A WEEK?

The majority of respondents said they visit approximately 5-10 work-related websites in a given week whilst

23% say they visit more than 10 websites per week.

23%

36%

32%

8%

2%

0% 5% 10% 15% 20% 25% 30% 35% 40%

More than 10

5-10

3-4

2

1



HOW OFTEN DO YOU VISIT BIOPHARMA-REPORTER.COM PER WEEK?

Approximately one third of biopharmaceutical industry professionals (32%) visit BioPharma-Reporter.com

approximately 3-4 times per week, with another 13% visiting between 5-10 times and 4% visiting more than

10 times per week.

4%

13%

32%

22%

30%

0% 5% 10% 15% 20% 25% 30% 35%

More than 10

5 – 10

3 – 4

2

1



WHICH OF THE FOLLOWING HAVE YOU USED THE INTERNET FOR YOUR WORK PURPOSES?

Results revealed that our respondents often use the Internet to read up on news and trends (82%). Sixty-

three percent use it for competitive intelligence and comparative work while 62% use the Internet to find

products, equipment and/or suppliers.

2%

31%

34%

36%

37%

39%

42%

62%

63%

82%

0% 10% 20% 30% 40% 50% 60% 70% 80% 90%

Other

Find pricing/financial information,Request price quotes,

Purchase products, Request samples

Business advice

Career research/job search

Social media updates, Connected via LinkedIn

Watch a webinar,Take part in an online conference,

Sent a question in a live debate

Training/workshop/tutorials/seminars

Find products, equipment, services and suppliers

Compare products across suppliers,Competitive Intelligence,

Peer reviews of products/suppliers,Find product availability information

News and trends



DO YOU USE THE INTERNET TO PROMOTE YOUR OWN BUSINESS?

More than half of our survey respondents (64%) use the Internet to promote their own business.

64%

YES NO

36%



WHEN RESEARCHING FOR A POTENTIAL WORK-RELATED PURCHASE/

INFORMATION, HOW VALUABLE DO YOU FIND THE FOLLOWING RESOURCES?

(1= NOT AT ALL VALUABLE, 5= VERY VALUABLE)

Search engines were found as the most valuable resource when conducting research for work-related

information. The following sources also came in at a close second: word of mouth, BioPharma-Reporter,

industry events and industry trade publications (websites).

1.8

1.9

2.4

2.9

3.3

3.5

3.7

3.7

3.7

3.7

3.8

0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0

Networking websites - Facebook

Networking websites - Twitter

Blogs

Networking websites - Linkedin

Industry trade publications - Print

Supplier websites

Industry trade publications - Websites

Industry conferences / trade shows /

in person seminars

BioPharma-Reporter

Word of mouth / peer / colleague

General search engines (Google, Yahoo!, Bing)



AS A RESULT OF VISITING A WEBSITE FOR WORK PURPOSES, HAVE YOU TAKEN ANY

OF THESE ACTIONS?

A vast majority (77%) said they have downloaded information as a result of visiting a website for work

purposes. Seventy-three percent stated they have downloaded a white paper whilst 60% have directly

contacted a supplier.

4%

24%

24%

55%

60%

73%

77%

0% 10% 20% 30% 40% 50% 60% 70% 80% 90%

None

Purchased product

Ordered samples

Passed commercial informationto a colleague

Contacted a supplier

Downloaded a white paper

Downloaded information foruse or future reference



AS A RESULT OF SEEING AN ADVERTISEMENT ONLINE, HAVE YOU TAKEN ANY OF

THESE ACTIONS?

Over half (57%) of our readers have visited the advertiser’s website after seeing an advertisement online.

Forty-four percent have forwarded the advertiser’s website to a colleague but in contrast, only 14% said they

have called the advertiser as a result.

14%

14%

17%

34%

43%

44%

57%

0% 10% 20% 30% 40% 50% 60% 70%

Called the advertiser

Purchased product from their website

None

E-mailed the advertiser

Bookmarked the advertiser’s

website for future reference

Forwarded the advertiser’s

website to a colleague

Visited advertiser’s website



WHICH ONLINE PUBLICATION ARE YOU RANKING AS THE MOST USEFUL?

A clear majority of our respondents (45%) ranked BioPharma-Reporter as the most useful online publication

for biopharmaceutical news, surpassing competitor publications by a considerable distance.

BioPharma-Reporter

Fierce Biotech

BioPharm International

#1

#2

#3

#4 GenEngNews Cell Culture Dish #5



ABOUT BIOPHARMA-REPORTER Breaking News on Biopharmaceutical Development & Manufacturing

BioPharma-Reporter.com is used by biopharmaceutical professionals around the globe to stay in touch with

the latest new views and issues impacting the fast moving global biomanufacturing sector.

The editorial team is dedicated to bringing you the news that matters. We find the facts behind the spin, ask

the difficult questions and report developments in the clear, concise and unbiased manner to help you make

business decisions that matter. Our commitment to covering every quarter of this market is second to none

and our traffic figures clearly demonstrate our strength.

*E-Newsletter readers in May 2016

* *Average monthly traffic figures for Feb – Apr 2016

BioPharma-Reporter’s prime objective is to deliver global content to the right people wherever in the world in

which they are operating.

E-Newsletter readers*

12,386

Average Users**

26,025

Average Pageviews**

55,243

AMERICAS 48%

EMEA 29%

APAC 23%

BioPharma-Reporter readers by region (Feb – Apr 2016)



HERE IS WHAT OUR READERS THINK!

“A succinct, informative source that I can review quickly each morning.”

- PHARMACOVIGILANCE MANAGER, UNITED STATES OF AMERICA

“They [BioPharma-Reporter] are accurate and prompt in their reporting of all technological and business

updates.”

- CHIEF SCIENTIST, UNITED KINGDOM

“It’s a good insight into overall industry trends and developments”

- PLANT DIRECTOR, INDIA

“I find Mr. Stanton's articles noteworthy and have a certain amount of trust in their works.”

- REGIONAL MANAGER, REPUBLIC OF KOREA

“Very useful information resource for my job.”

- BIOPROCESS SPECIALIST, CHINA

“Good information on the latest trends in biopharma sector.”

- MANAGER-BIOLOGICS, INDIA

GET IN TOUCH TODAY

For more information on BioPharma-Reporter’s comprehensive marketing solutions that complement your

traditional programs, please contact us today

DAN STANTON

[email protected]

Editor

BioPharma-Reporter

+33 49952 2872

BRETT CURTIS

[email protected]

Head of Sales

BioPharma-Reporter

+33 49952 7855

State of the Biopharmaceutical Industry 2016

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