st JULY 2017 - Liverpoolctrc.liv.ac.uk/Tools/BAccrual/Newsletter/20170808_july2017-news.pdf ·...
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31 st JULY 2017 NEWSLETTER 1
Transcript of st JULY 2017 - Liverpoolctrc.liv.ac.uk/Tools/BAccrual/Newsletter/20170808_july2017-news.pdf ·...
31st JULY 2017! NEWSLETTER!
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Highlights
• 732pa.entssofar(54inJuly).• Lastnewdiagnosis30thSEPTEMBER2017.• WorldChocolateDay–thewinners.
• Medialepicondyleauditdrivestrialapplica>on.• BOSSConsentedStudygrowingfast.
“Thefinalpushisontoboostnumbers,andmaximisedataquality–that’smyjob!”
DrEmmaCwiklinskiBOSSStudyManager
MonthlyCaseConfirma.onWeaskeveryhospitaltoclicktoconfirmcaseuploadseachmonth–thisistoconfirmpeoplearelookingforcases(toconfirmatrueincidence).
112sitesconfirmedthattheywereup-to-datelastmonth.(upfrom108lastmonth).
AberdeenAiredaleAneurinBevanBasingstokeBarnsleyHospitalBarnetandChaseBarkingBartsBasildonBedfordBetsiCadwaladrBirminghamBlackpoolBoltonBordersGeneralBuckinghamshireCalderdaleCalderdaleCardiffChesterChesterfieldColchesterCoventryCrosshouseCwmTafDerbyDudleyDoncasterDorsetCountyDumfriesDurhamEast&NorthHertsEastKentEastLancashireEpsomEdinburghFrimley
LET’S ALL GO GREEN BY THE END OF RECRUITMENT!
GloucesterGreatWesternHairmyresHarrogateHeartOfEnglandHinchinbrookHomertonHullImperialIpswichJamesPagetKeWeringKingsCollegeLancashireLeicesterLincolnshireLiverpoolLeedsLutonMaidstoneManchesterMedwayMidCheshireMidYorkshireMonklands&WishMorecambeBayNewcastleNorthamptonNorthCumbriaNorthMidlandsNorthMiddlesexNo[nghamOxfordPennine(NthManc)Pennine(Oldham)PeterboroughPoole
PortsmouthRobertJonesRotherhamRoyalAlexandriaRoyalBerkshireRoyalCornwallRoyalFreeRoyalSurreyRoyalUnitedBathSalisburySandwellScarboroughShrewsburySouthManchesterSouthportSouthamptonSouthTeesStGeorgesStHelensStockportSunderlandTamesideTauntonTaysideUCLWarringtonWestMiddlesexWestSuffolkWexhamParkWhippsCrossWhi[ngtonWirralWorthingWrigh>ngtonYorkWinchesterWolverhamptonWyeValley
MISSEDLASTMONTHBradfordBrightonGlasgowGreatOrmondStGuys(Evelina)LewishamMiltonKeynesNorfolkandNorwichNorthernDevonRaigmoreSheffieldSouthDevonWestHerts
MISSED2MONTHSEastSussexForthValleyMid-EssexRoyalNa>onalOrthoSwanseaWesternIsles
MISSED3MONTHS+BristolChelseaHillingdonInverclydeNthLincolnshire&GoolePrincessAlexandraQEHosptl,WoolwichNorthWestLondonNorthumbriaRoyalDevonWorcestershire
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Whohasrecruitedsofar?
• Airedale• AneurinBevan• Barking• Barnsley• Barts• Bath• Basildon• Bedford• Birmingham• Bradford• Brighton• Bristol• Buckinghamshire• Cambridge• Calderdale• Cardiff• Chelsea• Chester• Colchester• Coventry• Crosshouse• CwmTaf• Derby• Doncaster• Dudley• Durham• East&NthHerts• EastKent• EastLancs• EastSussex
“116 UK SITES NOW RECRUITED”
LastMonth’sTop5
BirminghamFrimley
GloucesterLeeds
RoyalCornwall
• Edinburgh• Epsom• Frimley• ForthValley• Glasgow• Gloucester• GreatWestern• GreatOrmondSt• Guys• Hillingdon• Hinchinbrooke• Hull• Imperial• Ipswich• KeWering• Kings• Lancashire• Leicester• Lewisham• Leeds• Liverpool• Luton• No[ngham• Manchester• Maidstone• Medway• Mid-Essex• MiltonKeynes• MidYorks• MorecambeBay
• Newcastle• NorthMidlands• Northampton• Northumbria• NorthDevon• NorthMiddlesex• Norwich• No[ngham• Oxford• Pennine(Oldham)• Peterborough• Plymouth• Poole• Portsmouth• PrincessAlexandra• Raigmore• RobertJones• Rotherham• RoyalAberdeen• RoyalAlexandria• RoyalBerks• RoyalCornwall• RoyalDevon&Exeter• RoyalFree• RoyalNa>onalOrth• RoyalBerks• RoyalSurrey• Sandwell• Sheffield• Southport
• SouthDevon• SouthTees• Southampton• Stockport• StGeorges• Sunderland• Swansea• Tameside• Taunton• Tayside• UnitedLincoln• Warrington• WestHerts• WestMiddlesex• WestSuffolk• WexhamPark• Whi[ngton• Wirral• Wishaw• Wolverhampton• Worcester• Worthing• Wrigh>ngton
32sitesrecruitedinJuly2017–ChocolatesforWorldChocolateDayonwaysoon!
Wolverhampton&SouthDevonforthefirst>me–thankyou!
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Inves.gatorsMee.ng:CaseDefini.on:SlippedEpiphysis-Allnewcasesofdiseaseagerfixa>on.Perthes’Disease–Allnewcasespresen>ngtodefini>vecareclinician(i.e.maybediagnosed6monthsagobuttakensome>metobereferredtothepersonmakingdecisionsaboutmanagement).
FOLLOW-UPREMINDERSHowtofollow-upcases-Themonthlye-mailwillremindyouaboutwhoisduefollow-up.Tofollow-upcases,pleasegointoRedCap(thelinkfromwww.BOSS.surgeryusingamobilephone/tabletcomputeriseasiest).Ratherthanclicking“addnewcase”,selectthepa>ent’snumber(i.e.12-1)andthen“3monthf/u”.Ifyoudoaccidentallyaddanincorrectnewcasethenpleaseno>[email protected].
ThankstoallthosewhoaWendedtheWebinars.WewillputalinktotherecordedWebinaronBOSS.surgery–andalinkisinthismonth‘se-mail.
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DataQueries:PaulTate,theBOSSdatamanager,willbecheckingafewthingsthroughtheweb-versionofRedCap.Pleasehelpoutbyloggingintocheckthem.
MonthlyEmail.Pleaseconfirmcaseuploadsbyclickingthelinkinthee-mail,ratherthane-mailingus–itissimplertomanage(andtakesabout10secs).AccrualNumbers…There are 732 records in REDCap, howeversomeareineligiblepar>cipants(includedinthegraph for the surveillance cohort), or cases forwhomeligibilityqueriesneed tobe raised.Wewillcontactsurgeonsdirectlytoaddressqueriesrelated to theeligibility. Thank you forhelpingustoresolvethesequeries.ConsentFormsPleasesendconsentformsalongwiththeconsenttrackingformv3(previousversionsarenolongerused).
ConsentedCohort……Why?Gainingconsentforlong-termfollowupandthecollec>onofpa>entreportedoutcomesisafundamentalpartofBOSS.ThisexaminestheuseofPROMSinthispopula>on,andgivesaclearerideaofoutcomes.Who?Everyhospitalcanenrollconsentedpa>ents,thoughthisrequiresaddi>onalsetup([email protected]).Pa.entscanbeenrolledatany.meduringthestudy-eveniftheywererecruitedintotheconsentedcohortlastyear.Trials?Gainingconsents>mulatesthedevelopmentoflocalinfrastructureinpaediatricorthopaedicunitsbeforeothertrialsbegin(researchunitsgetanaddi>onal‘accrual’foreachpa>entconsented).
Surveillanceonlysites,weneedyourhelp!…Inordertoallowmeaningfulanalysisoftheresults,weneedasmanyaspossibleineachdiseasegroup.Atpresent,wehave165pa>entsacrossbothSCFEandPerthes’disease.Ifyourcentreisnotopentorecruittotheconsentedcohort,thenpleasepointpa>ents(atanystageoftheir
follow-up)totheBOSSwebsite(www.BOSS.surgery).Pa>entscanregistertopar>cipateintheconsentedcohortthroughthewebsite,andaresearchnurseatAlderHeywillcontactthem.
Everypa.entcanhavetheopportunitytopar.cipateinthesurveillanceandconsentedcohort.
MessagesfromEmma…([email protected])!Pa.entconfiden.alityPleasedon’tshareanyconfiden>alpa>entdatawiththeBOSSteam.Amendment09From4/8/2017allhospitalsshouldbeworkingtoV5.0(30thMarch2017)oftheprotocol(unlessyourR&Dhassaidtheyneedmore>me).Youshouldreceiveacopyofthecontactcardsandposterinthenextfewdays.Wewillmakealinktotheprotocolonthewebsite.HospitalTransfersIf a pa>ent permanently moves hospital agerbeing enrolled in the study - for whateverr e a s o n , t h e n p l e a s e c o n t a c t([email protected]). Please include thepa>entstudyIDnumber,andthenewhospital.(Remember – we are not allowed to knowpa>entnamesandfullDOBetc.).Wewill liaisewith thenewhospital toensure that follow-upispossible.
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The44hospitalscurrentlywithpermission(i.e.whohavegonethroughtheprocesstotakeresearchconsent)arelistedbelow…
Consen.nghospitals…
Hospitalswithgoodconsentratesoverthenext6monthswillbeinvitedfirsttopar.cipateinforthcomingtrials-establishedinfrastructureisvitaltomaximisetrialdelivery.Hospitalshavetheafewmonthstobecome100%ers! 7
SiteName Percent
Bedford 100
Kejering 100
Maidstone 100
AbertaweBroMorgannwg(Swansea) 100
MorecambeBay 100
WestMiddlesex 100
LancashireTeachingHospitals(Preston) 88
EastLancashire 87
NorfolkandNorwich 73
RobertJonesandAgnesHunt 73
Plymouth 67
AlderHey 62
RoyalNa.onalOrthopaedic 60
NewcastleUponTyneHospitals 60
NorthMidlands(Stoke) 53
LeedsGeneralInfirmary 50
RoyalBerkshire 43
Southampton 41
CoventryandWarwick 36
DarlingtonNHS 33
MidYorkshire 33
NorthamptonGeneral 33
NoonghamUniversity 29
ColchesterHospital 25
EastSussex 25
NHSGreaterGlasgowandClyde 9
Barking,HaveringandRedbridge 0
Barnsley 0
Barts 0
BasildonandThurrock 0
BrightonandSussex 0
Buckinghamshire 0
Cardiff 0
Manchester 0
Doncaster 0
GreatOrmondStreet 0
LutonandDunstable 0
Oxford 0
Peterborough 0
Sheffield 0
Shrewsbury 0
Bristol 0
HeartOfEngland 0
Wrigh>ngton,WiganandLeigh 0
MedialEpicondyleTrial…fixornot?ANIHRexpressionofinterestfor£1mtodeliveratrialhasbeensubmiWed–weknowmanyofyouarekeentobepartofthis…
Geta“luxury”BOSSMugs–JulywinnerTBCsoon!
ToprecruiterstotheconsentedstudyinAugust….
TrialFeasibility-Traineesin30centrescarriedoutanauditof3yearsofmanagement–theheadlines…• Fewfracturestoanyunit(but507combined).• Widespreaddisagreementintx(strongevidenceofequipoise).• Overall-45%fixed(228),55%(279)treatedconserva>vely.• Atrialispossiblewithalargenumberofunits.• Traineecollabora>veimportanttodelivertrial.
