SPEX SamplePrep Freezer/Mill®...• Extensive library of Freezer/Mill® applications Examples •...

© SPEX SamplePrep, Inc. 2011

SPEX SamplePrep Freezer/Mill®


Why Cryogenic Grinding?

•  Many analytical samples are too flexible or sensitive to be ground at ambient temperatures

•  Samples are subject to degrading •  Does not damage DNA or RNA


The Basics

•  Samples are chilled at Liquid Nitrogen (LN) temperatures and ground using a Magnetically-Driven Impactor – No mechanical linkages or bearings

to fail •  Sealed Grinding Vials ensure

sample integrity •  Touch screen display w/ stored

procedures for rapid process replication and consistency


Who Can Benefit From a Freezer/Mill®?

•  Forensic Labs – DNA identification •  Medical Labs– genetic research, disease

prevention •  Hospital Labs – For genetic screening •  Agricultural Labs – For crop development •  Agricultural Veterinary Labs – For livestock

breeding and health •  Archealogy Labs – Ancient DNA extraction •  Public Health and Environmental Monitoring

Labs •  QC Testing of Manufactured Goods •  Electronics Companies – Grinding Electronic

Components


The Freezer/Mill® Family

Sample Size

0.6 – 5 g 0.6 – 100 g 0.6 – 200 g

LN System

Manual Manual, Auto-Fill Option

Auto-Fill Only

Price $ $$ $$$


6970EFM – Features & Benefits

•  Two Models Available – Single Grinding Chamber (6970M)

•  1 Grinding Chamber + 1 Pre-Cooling Chamber

– Dual Grinding Chambers (6970D)

•  Totally enclosed auto-fill system with no Liquid Nitrogen exposure

•  Increased through-put – Up to 8 small vials or 2 large vials

(D model only)


6770 – Features & Benefits

•  Cost efficient •  Runs one Micro-vial or small vial per run •  Perfect for smaller samples (5 grams or

less) •  Additional area for pre-cooling samples •  Unit has small counter footprint


6870 – Features & Benefits

•  Versatile large grinding chamber – Runs a variety of vials, ranging from micro

vials through the large, even up to 4 of the small vials

– Allows for wide range of sample sizes •  Available with Auto-Fill,

or without •  Additional area for

pre-cooling samples


Freezer/Mill Accessories


Freezer/Mill Vials & Vial Sets

Micro Small Mid-Size Large 0.1 – 0.5 mL 0.5 – 4.0 mL Up to 25 mL Up to 50 mL 0.1 – 0.5 g 0.5 – 4.0 g Up to 40 g Up to 100 g

•  Standard Set •  Stainless Steel End Plugs & Impactor with Polycarbonate Center

Cylinder •  Polycarbonate

•  Avoids metal contamination •  Stainless Steel

•  Best for Polymer applications •  Cr-Free

•  For RoHS/WEEE appliactions


Freezer/Mill Auto-Extractor

6814 Auto-Extractor™ •  Works with Small and

Large size vials •  Increases throughput •  Reduces operator effort


Freezer/Mill Accessory Packages

Includes:

•  6754 Small Extractor

•  6755 Vial Rack •  6806 Multi-Vial

Adapter

Includes:

•  6884 Mid-Size Adapter for 6804 Large Extractor

•  6886 Mid-Size Grinding Vial Adapter Includes:

•  6804 Large Extractor

•  6805 Vial Rack


Freezer/Mill Liquid Nitrogen Handling

•  Cryogenic Gloves

•  Portable Dewars & Pressurized Tanks – Required for use with Auto-Fill units

(6870 + Auto-Fill & 6970EFM)


Samples, Application Notes & Resources


Before & After…

Leather

Corn

Bone A Collection of our Before &

After Samples


Application Notes

•  Extensive library of Freezer/Mill® applications

Examples •  SP005 – RNA Extraction from

Cartilage Tissue Using Cryogenic Grinding

•  SP006 – Preparation of Rice Husks for the Analysis of Their Contents

•  SP007 – Grinding Polymers For Qualitative and Quantitative Analysis

Also Available:


Product Demonstration Videos

SPEX SamplePrep Freezer/Mill®...• Extensive library of Freezer/Mill® applications Examples •...

Documents

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