SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva,...

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SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov, A.S.Vorozhtsov, N.L.Zaplatin Dzhelepov Laboratory of Nuclear Problem, Joint Institute for Nuclear Research, 141980, Str. Joliot-Curie, 6, Dubna, Russia, fax:+7-09621-66666, corresponding author e-mail address: [email protected]

Transcript of SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva,...

Page 1: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION

Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B.

Vorozhtsov, A.S.Vorozhtsov, N.L.ZaplatinDzhelepov Laboratory of Nuclear Problem, Joint

Institute for Nuclear Research, 141980, Str. Joliot-Curie, 6, Dubna, Russia, fax:+7-09621-66666,

corresponding author e-mail address: [email protected]

Page 2: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Dubna scientific medicine center is under development since 1967 on the base of the proton beam of LNP JINR Phazotron.[1] Proton beam with

energy Ер~170 MeV and intensity I~0.1 mkA is used for patients irradiation. Proposal of creating of the cyclotron with the same beam characteristics was reported earlier at the conferences RUPAC04 [2],

ICAA05 [3]

Page 3: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Isochronous cyclotron for proton therapy is proposed to be created on the basis of a compact four sectors magnet with circle

return yoke having an outside diameter 5.2 м and height 2.4 m. Some types of the

return yokes were calculated to compare them.

Page 4: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Magnet system of

proton cyclotron

C220p plane view (circle

return yoke).

Page 5: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Modeling of the cyclotron magnetic system was carried out with the help of the program Radia, which works in computation system Mathematica and calculates a magnetic field of three-dimensional magnetic systems by a method of the integrated equations. As a material of a magnet the steel - 10 was used.

Page 6: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Page 7: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

The cyclotron vacuum chamber from above and from below is limited to poles and yokes of a magnet. The winding of excitation of a magnet is separated from vacuum volume by two not magnetic rings, which are located between poles and vertical yoke of a magnet and has with them vacuum dense connections.

Page 8: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Magnet system of proton cyclotron С220p cross section along sector shim.

Page 9: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Page 10: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Profile and plan view the magnet with various return yokes.

Page 11: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Magnet system of proton cyclotron С220p (two symmetry return yoke), Ш- tape magnet.

Page 12: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Magnet system of proton cyclotron С220p plane view (four symmetry return yoke).

Page 13: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Page 14: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Comparison Radia (Mathematica) – TOSCA calculation of magnet system with sector shims

Bmean, C200p, Iw=170kA

1.1

1.2

1.3

1.4

1.5

1.6

1.7

0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150

R [cm]

Bmea

n [T

esla

]

A.Vorozhtsov S.Kostromin Model 2

Page 15: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Calculated field from the angular extent by one degree sectors

Page 16: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Betatron frequencies along radius

Page 17: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

1,00 1,05 1,10 1,15 1,20 1,250,0

0,1

0,2

0,3

0,4

0,5

0,6

0,7

Qr-2Qz

=1

210 MeV

10 MeV

Qr+2Q

z=2

Point distance=10 MeV

Qr-Qz

=1

Qz

Qr

Working point diagram along the acceleration in C200р is presented in Fig.6. The point to point distance is 10 MeV. The most dangerous resonance Qr-Qz=1 is crossed two times at energies 130 and 170 MeV. Modeling of particle dynamics showed that no axial amplitude increase observed after the resonance (see below) if no skew harmonics presented in magnetic field map. Further computations have to define permissible limits of such harmonics.

Page 18: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Proton resonance orbital frequency is 20.4545 MHz. Axial particle motion along acceleration in magnetic field is shown with no skew harmonics. Amplitude of particle radial oscillation was 5 mm in this computations. Changing of axial oscillations amplitude corresponds to the dependence of axial betatron frequency on the radius.

Page 19: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Rectilinear on radius the accelerating resonators which have angular extent 42º and 30º dee are used. They are located in valleys, where the gap between poles is 400 mm. The adjustment and excitation of resonators is carried out through coaxial lines. The central rod located from above and from below is used for dee support. Parts of lines, which leave for the size of 400 mm are placed in channels of poles of a magnet.

Page 20: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

resonance frequency (MHz) 81,8

case dimensions

radial (Rmax) (mm) 1500

height (mm) 400

azimuth () 50

dimensions -electrod (dee)

max.rad.(Rmax)(mm) 1400

height (mm) 50

aperture (mm) 30

azimuth () 30

Accelerating gap () 6

Coaxial line dimensions

Between clothe contact plates (mm) 800

Radius of coaxial lineinner (mm)outer (mm)

100180

From center of accel. to acces (mm) 750

Page 21: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Conclusions The physical consideration of proton

cyclotron on energy of the beam Ep ~220 MeV was given. This cyclotron will provide all scientific and medical programs on the medical beam of Dzhelepov Laboratory of Nuclear Problem, Joint Institute for Nuclear Research.

On the basis of this project the cyclotron for the medical centers in other interested organizations can be created.

Page 22: SPECIALISED CYCLOTRON FOR BEAM THERAPY APPLICATION Yu. G.Alenitsky, A.A.Glazov, G.A.Karamysheva, S.A.Kostromin, L.M.Onischenko, E.V.Samsonov S.B. Vorozhtsov,

Spec. cyclotron for beam therapy Spec. cyclotron for beam therapy applicationapplicationRUPAC06RUPAC06

Thank you for your attention