Special considerations in children with vitiligo considerations in children with vitiligo February...
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Special considerations in children with vitiligo February 17 th , 2018 Pearl Grimes, MD Director, Vitiligo & Pigmentation Institute Of Southern California Clinical Professor of Dermatology, UCLA www.pearlgrimesmd.com Quality of Life: Vitiligo is indeed a psychologically devastating disease. Children comprise 25% of patients. When this disorder begins in childhood, it is often associated with profound emotional trauma for affected children. Negative experiences related to the disease in childhood are often associated with long standing social adjustment issues. Epidemiology: There are no differences in the pathogenesis of childhood and late onset disease; however unique aspects of childhood disease include: • higher prevalence of segmental vitiligo • positive family history • atopic dermatitis. Associated conditions: While associated autoimmune diseases are more common in adults with vitiligo, multiple studies have documented an increased frequency of thyroid disorders in children with vitiligo. Treatment: Excellent therapeutic outcomes are often achieved in children. Therapies for childhood vitiligo incorporate modalities for stabilization and repigmentation. • oral and topical corticosteroids • calcineurin inhibitors • NB-UVB phototherapy. Other Special Considerations in children • Increased prevalence of segmental vitiligo • Enhanced response to treatment modalities compared to adults REFERENCES: Driessche FV, Silverberg N. Current Management of Pediatric Vitiligo. Pediatr Drugs 2015; 17: 303-313 Agarwak S, Gupta S, Ojha A, Sinha R. Childhood Vitiligo: Clincoepidemiologic Profile of 268 Children from Kumaun Region of Uttarakhand, India. Pediatric Dermatology 2013 30:348-353 Grimes PE. 2016 Jun. Vitiligo: Pathogenesis, Clinical Features, and Diagnosis. H Tsao (Ed.), UpToDate. Retrieved from [http://www.uptodate.com/contents/vitiligo-pathogenesis-clinical- features-and-diagnosis? source=search_result &search= grimes+vitiligo&selectedTitle=4%7E88] Phiske MM. Vitiligo in Children: A Birds Eye View. Curr Pediatr Rev. 2016; 12(1): 55-56
Transcript of Special considerations in children with vitiligo considerations in children with vitiligo February...
Special considerations in children with vitiligo February 17th, 2018
Pearl Grimes, MD Director, Vitiligo & Pigmentation Institute Of Southern California Clinical Professor of Dermatology, UCLA
www.pearlgrimesmd.com
Quality of Life: Vitiligo is indeed a psychologically devastating disease. Children comprise 25% of patients. When this disorder begins in childhood, it is often associated with profound emotional trauma for affected children. Negative experiences related to the disease in childhood are often associated with long standing social adjustment issues.
Epidemiology: There are no differences in the pathogenesis of childhood and late onset disease; however unique aspects of childhood disease include:
• higher prevalence of segmental vitiligo • positive family history • atopic dermatitis.
Associated conditions: While associated autoimmune diseases are more common in adults with vitiligo, multiple studies have documented an increased frequency of thyroid disorders in children with vitiligo. Treatment: Excellent therapeutic outcomes are often achieved in children. Therapies for childhood vitiligo incorporate modalities for stabilization and repigmentation.
• oral and topical corticosteroids • calcineurin inhibitors • NB-UVB phototherapy.
Other Special Considerations in children
• Increased prevalence of segmental vitiligo • Enhanced response to treatment modalities compared to adults
REFERENCES:
Driessche FV, Silverberg N. Current Management of Pediatric Vitiligo. Pediatr Drugs 2015; 17: 303-313
Agarwak S, Gupta S, Ojha A, Sinha R. Childhood Vitiligo: Clincoepidemiologic Profile of 268 Children from Kumaun Region of Uttarakhand, India. Pediatric Dermatology 2013 30:348-353
Grimes PE. 2016 Jun. Vitiligo: Pathogenesis, Clinical Features, and Diagnosis. H Tsao (Ed.), UpToDate. Retrieved from [http://www.uptodate.com/contents/vitiligo-pathogenesis-clinical-features-and-diagnosis? source=search_result &search= grimes+vitiligo&selectedTitle=4%7E88]
Phiske MM. Vitiligo in Children: A Birds Eye View. Curr Pediatr Rev. 2016; 12(1): 55-56
