Sohi Rastegar Engineering Advisory Committee

October 16, 2012

CBET Mission and Purpose

(CBET) supports research and education in the rapidly evolving fields of bioengineering and environmental engineering and in areas that involve the transformation and/or transport of matter and energy by chemical, thermal, or mechanical means

These investments contribute to advances that are important for the environment, energy, information technologies, health-related products, and other areas that impact our daily lives.

• Sustainability • Water, Energy, Climate, Environment Nexus • Sustainable, Advanced Manufacturing: Chemistry, Engineering and Materials • Critical Elements and Materials • Advances in engineering to stimulate the bio-economy • Environmental Health & Safety of Nanotechnology (nanoEHS)

• Healthcare • Neurobiology • Synthetic Biology • Robotics for Disabled and Aged • Bio-Sensing & Bio-photonics for “smart” healthcare diagnostics

and treatment strategies • More partnerships and more use-inspired flavor

Current & Future Areas of Focus

0

500

1000

1500

2000

2500

3000

3500

4000

Environmental Chem Transport Bioeng Division

Compe

titive

Pro

posa

l Act

ions

New Cluster Organization

2006

2007

2008

2009

2010

2011*

CBET Experienced Rapid & Significant Growth in Environmental & Bioengineering

Changes in CBET Proposal Submissions due to “Single Window” Policy

FY10 FY11 FY12

Total 3645 3752 3164 (about 16% decrease)

FY11 FY12 FY13

Fall Only 1089 1055 (about 5% decrease)

All Four Clusters Can Potentially Affect Strategic Areas in CBET Portfolio (Clean Energy)

7.4

1.6

4.7

3.7

5.0

5.6

8.0

4.2

1.0

2.4

3.7

1.9

11.4

1.9

3.4

3.5

7.0

2.0

6.7

3.3

0.2

0.4

4.3

1.1

1.0

$- $10.00 $20.00 $30.00 $40.00

Catalysis and Biocatalysis

Chemical and Biological Separations

Process and Reaction Engineering

Biotechnology, Biochemical, and Biomass …

Energy for Sustainability

Environmental Sustainability

Combustion, Fire, & Plasma Systems

Interfacial Processes and …

Particulate and Multiphase Processes

Thermal Transport Processes

Awards ($ Million)

Advanced Green Micro/Nano Traditional Other

All Four Clusters Can Potentially Affect Strategic Areas in CBET Portfolio (Adv. Manufacturing)

Data as of February, 2011 for Active Awards

0

5

10

15

20

25

30

2007 2008 2009 2010 2011 2012

Fund

ing

Rat

e (%

)

NSF

ENG

CBET

Relative Funding Rates are Consistent between CBET and NSF, ENG Directorate

$0.00

$20,000.00

$40,000.00

$60,000.00

$80,000.00

$100,000.00

$120,000.00

$140,000.00

$160,000.00

$180,000.00

2007 2008 2009 2010 2011 2012 * Data do not reflect no-cost extensions for more recent years

Mean Annual Award Size

NSF

ENG

CBET

0

0.5

1

1.5

2

2.5

3

3.5

4

4.5

2007 2008 2009 2010 2011 2012 D

urat

ion

(yea

rs)

* Data do not reflect no-cost extensions for more recent years

Mean Award Duration

NSF

ENG

CBET

Award Size and Duration Have Remained Stable

Balance of Single & Multiple PI Awards in CBET

0.00%

20.00%

40.00%

60.00%

80.00%

100.00%

120.00%

2009 2010 2011 2012

Distribution of CBET Proposals by # PIs

3+ PI's

2 PI's

1 PI

0.00%

20.00%

40.00%

60.00%

80.00%

100.00%

120.00%

2009 2010 2011 2012

Distribution of CBET Awards by # PIs

3+ PI's

2 PI's

1 PI

CBET Has Stable CAREER Support as Fraction of Budget

0%

2%

4%

6%

8%

10%

12%

14%

16%

18%

20%

FY2002 FY2003 FY2004 FY2005 FY2006 FY2007 FY2008 FY2009 FY2010 FY2011

All Competitive Proposals Submitted FYs 2009 & 2010

Most CBET Awards to ChEs, MEs & BMEs

0.00%

5.00%

10.00%

15.00%

20.00%

25.00%

30.00%

Geographic Distribution of CBET Awards FYs 2009-2011

Current & Future Research Areas in CBET Are Highlighted by Participation in Various Cross-Platform Initiatives • Internal

• Broadening Participation Research Initiation Grants in Engineering 2012 (BRIGE)

• Computation and Data-Enabled Science and Engineering (CDS&E) • Supplemental Opportunity for Translational Research in the Academic

Community (TRAC) • Network for Computational Nanotechnology • Scalable Nanomanufacturing (SNM) • SusChEM-Targeted Proposals • SEES Components: SEES Fellows, SRN, & RCN-SEES Awards

• Inter-Agency • NSF-NIST Interaction in Basic and Applied Scientific Research in BIO, ENG &

MPS • NSF/DOE Partnership in Basic Plasma Science and Engineering • NSF/DOE Partnerhsip on Advanced Combustion Engines • NSF/FDA Scholar-in-Residence at FDA • Physical and Engineering Sciences in Oncology (PESO) • NSF/CPSC MOU in Nano EHS

CBET PDs actively lead and support ERCs, STCs, and EFRI • ERCs

Leads: • NSF-ERC for Revolutionizing Metallic Biomaterials (RMB) • ERC for Re-Inventing America’s Urban Water Infrastructure (ReNUWIt) Supports: • ERC for Biomimetic MicroElectronic Systems (BMES) • Synthetic Biology Engineering Research Center (SynBERC) • ERC for Mid InfraRed Technologies for Health and the Environment (MIRTHE)

• STC (Leads) • Emergent Behaviors of Integrated Cellular Systems

• EFRI Leads:

• Cellular and Biomolecular Engineering (CBE) • Resilient and Sustainable Infrastructure (RESIN) • Engineering Technologies for Multicellular and Interkingdom Signaling (MIKS) • Hydrocarbon from Biomass (HyBi) • Photosynthetic Biorefinaries (PSBR) Supports: • Cognitive Optimization (COPN) • Flexible Bioelectronic Systems (BioFlex)

CBET Imagines a World Where… Humans Will Live Sustainably on Earth

The Quality & Length of Life Will Be Maximized

Tongue Drive System for Individuals with Quadriplegic Paralysis

Credit: Ghovanloo, Georgia Institute of Technology

Bryc

e Ri

chte

r

• Drinking water will be clean and availability sustainable

Removal of pharma molecules via adsorption with a silica rich surface grafted with nickel-

based complexes. Credit: Hernandez-Maldonado (UPR-Mayaguez)

• New, sustainable approach to environmental technologies such as water disinfection and surface disinfection. Credit: Kim, Georgia Institute of Technology

Humans Will Live Sustainably on Earth

• Air, ground and sea transportation will be safe and efficient • Advanced Cooling technology leading to:

- Desktop Supercomputers - Higher Efficiency Engines - Higher Efficiency Heat Exchangers for Autos, HVAC & Power Plants

Chip & Data Center Cooling

Inside an engine

IC Engine

Humans Will Live Sustainably on Earth

• Protect air, water, land and climate • Control and abate pollutants • Reduce & reuse greenhouse gas emissions • Protect humans from nanotechnology before

widespread environmental infiltration Catalytic Membrane Design: As ethanol diffuses through the membrane, it is catalytically broken down first into methane and carbon monoxide, and subsequently into hydrogen and carbon dioxide. Steam and air ensure complete reaction of carbon monoxide pollutant. Credit: Benjamin A. Wilhite, Texas A&M University, College Station, TX

Humans Will Live Sustainably on Earth

The Quality & Length of Life Will Be Maximized

• Optogenetics will make it possible to probe neural circuits in live mammals to understand physiologic and pathologic neuro-psychiatric function

• Neural engineering will make it possible to study the brain and to develop minimally-invasive methods to diagnose and treat neural disorders

• Build brain-like devices

The Quality & Length of Life Will Be Maximized

Thank You

• A thriving bio-economy will use bio-renewable and renewable resources to produce sustainable fuels and chemicals

CO2

acetyl-CoA

“Green hydrocarbon biofuel”

Engineered algae and photo-bioreactor for production of energy dense hydrocarbons. Wayne Curtis, Penn State

Humans Will Live Sustainably on Earth

CBET Experiences high Proposal Loads and Low Award Rates

FY10 Research Grants FY11 Research Grants FY12 Research Grants

0

500

1000

1500

2000

2500

3000

3500

ECCS 17%

CBET 15%

CMMI 14%

EFRI 22%

EEC 14%

IIP 61%

Competitive Proposal Actions

Competitive Awards

0

500

1000

1500

2000

2500

3000

3500

4000

4500

ECCS 17%

CBET 12%

CMMI 14%

EFRI 25%

EEC 14%

IIP 42%

Competitive Proposal Actions

Competitive Awards

0

500

1000

1500

2000

2500

3000

3500

4000

4500

ECCS 17%

CBET 11%

CMMI 15%

EFRI 23%

EEC 21%

IIP 68%

Competitive Proposal Actions

Competitive Awards

CBET In 0 Words

BEH

EES TTF

Backman, Northwestern

Desjardin, SUNY Buffalo

CBBS

Funding Rates by Directorate indicate stresses on ENG

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

OPP GEO SBE MPS CISE BIO ENG .EHR

2009 2010 2011 2012 Average

Trends in CBET Fund Distribution: “BES” Has increased substantially

CBBS

TTF

BEEH

EES

CTS (9) ~ 69%

BES (7) ~ 31% CBBS

TTF

BEEH

EES

CTS (9) ~ 52% BES (8) ~ 48%

12/2006 12/2010

BIO

CSE EHR

ENG

GEO

MPS

OCI OISE OPP

SBE

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

2002 2003 2004 2005 2006 2007 2008 2009 2010

Prop

osal

s

FY 2010 Merit Review Report

Proposals by Directorate indicate stresses on ENG