Smoking Cessation for Persons with Mental Illness · smoking cessation to the needs of smokers with...

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Smoking Cessation for Persons with Mental Illness

Transcript of Smoking Cessation for Persons with Mental Illness · smoking cessation to the needs of smokers with...

Smoking Cessation for Persons with Mental Illness

O V E R V I E W | 1

Why is a smoking cessation toolkit for persons with mental illnesses needed?

They need to quit.Consumersneedtobealiveto“recover”frommentalillnesses.Smokingcessationisakeycomponentofconsumer-driven,individualizedtreatmentplanning.

They want to quit.Peoplewithmentalillnesseswanttoquitsmokingandwantinformationaboutcessationservicesandresources.(Morrisetal,2006)

They can quit.Peoplewithmentalillnessescansuccessfullyquitusingtobacco.(Evinsetal.,2005;Georgeetal.,2002).Significantevidenceshowsthatsmokingcessationstrategieswork.

Note: Throughoutthistoolkittheterms“tobaccouse”and“smoking”areusedinterchangeably.Althoughwedonotspecificallyaddressspit-tobaccouse,thetoolkitisgenerallyapplicabletospit-tobaccousers.

“I’d love to quit – I just don’t know how.”– John, age 45

O V E R V I E W | 2

Alarming StatisticsApproximately 7.7 percent of Colorado’s adult population has a major mental illness.1

Forty-onepercentoftheseindividualsusetobacco.Theprevalenceofsmokingamongpeoplewithmentalillnessesisstartling.

By diagnosis:Majordepression 45-50percentBipolarmooddisorder 50-70percentSchizophrenia 70-90percent

Americanswithmentalillnessesrepresentanestimated44.3percentofthetobaccomarket.2

Americanswithmentalillnessesarenicotinedependentatratesthataretwotothreetimeshigherthanthegeneralpopulation.3

Becausepeoplewithmentalillnessesusetobaccoatgreaterrates,theysuffergreatersmoking-relatedmedicalillnessesandmortality.4

About this toolkitWho is this toolkit for?Thistoolkitwasdevelopedforabroadcontinuumofmentalhealthproviders.Materialsareintendedfordirectproviders,aswellasadministratorsandbehavioralhealthorganizations.

How do I use this toolkit?Thetoolkitcontainsavarietyofinformationandstep-by-stepinstructionabout:•Lowburdenmeansofassessingreadiness toquit•Possibletreatments•ReferraltoColoradocommunityresources

1] Morris et al., 20062] Grant et al., 2004, Lasser et al., 20003] Grant et al., 2004, Lasser et al., 20004] Grant et al., 2004

Quick FactsMental Illnesses and Tobacco Use

• 7.1%oftheU.S.populationhasapsychiatricillness;however,thispopulation consumesover34.2%ofallcigarettes.(Grantetal.,2004)

• IntheU.S.,personswithmentalillnessesrepresentanestimated44.3%ofthetobacco marketandarenicotinedependentatratesthatare2-3timeshigherthanthegeneral population.(Grantetal.,2004;Lasser,2000)

• InColorado,approximately7.7%oftheadultpopulationhasamajormentalillnessand 41%oftheseindividualsusetobacco.(Gieseetal.,2003)

• Smokingcessationisakeycomponentofconsumer-driven,individualizedtreatment planning.(Morrisetal.,2006)

• Personswithmentalillnesseswanttoquitsmokingandwantinformationoncessation servicesandresources.(Morrisetal.,2006)

• Personswithmentalillnessescansuccessfullyquitusingtobacco.(Evinsetal.,2005; Georgeetal.,2002)

• SmokingquitratesforindividualswithpsychiatricillnessareNOTsignificantlylower thanthegeneralpopulation.(el-Guebalyetal.,2002)

• Becausepersonswithmentalillnessesusetobaccoatgreaterrates,theysuffergreater smoking-relatedmedicalillnessesandmortality.(Grantetal.,2004)

References:

El-GuebalyN,CathcartJ,CurrieSetal(2002).Smokingcessationapproachesforpersonswithmentalillnessoraddictivedisorders.Psychiatric Services,53(9):1166-1170.

EvinsAE,MaysVk,RigottiNA,etal.(2001).Apilottrialofbupropionaddedtocognitivebehavioraltherapyforsmokingcessationinschizophrenia.Nicotine Tobacco Research,3(4):397-403.

GeorgeTP,VessicchioJC,TermineAetal.(2002b).Aplacebo-controlledstudyofbupropionforsmokingcessationinschizophrenia.Biological Psychiatry,52(1):53-61.

GieseA,MorrisC,OlincyA(2003).Needsassessmentofpersonswithmentalillnessesfortobaccoprevention,exposure,reduction,andcessation.ReportpreparedfortheStateTobaccoEducationandPreventionPartnership(STEPP),ColoradoDepartmentofPublicHealthandEnvironment.

GrantBF,HasinDS,ChouPS,StinsonFS,DawsonDA(2004).NicotinedependenceandpsychiatricdisordersintheUnitedStates:resultsfromthenationalepidemiologicsurveyonalcoholandrelatedconditions.Archives General Psychiatry,61(11):1107-1115.

LasserK,BoydW,WoolhandlerS,etal(2000).Smokingandmentalillness:apopulationbasedprevalencestudy.Journal of the American Medical Association,284:2606–2610.

MorrisCD,GieseJJ,DickinsonM,Johnson-NagelN.(2006).PredictorsofTobaccoUseAmongPersonsWithMentalIllnessesinaStatewidePopulation.Psychiatric Services,57:1035-1038.

TobaccoDisparitiesInitiativesoftheStateTobaccoEducationandPreventionPartnership(STEPP),ColoradoDepartmentofPublicHealthandEnvironmentwww.cdphe.state.co.us/pp/tobacco/tobaccohome.asp

Smoking and mental illnesses: nicotine effects and other considerationsPeoplewithmentalillnesses:•usetobaccoathigherrates• arelesslikelytosucceedatcessationattempts•accessgeneralmedicalservicesandother communityresourcesrelativelyinfrequently• strugglewithstigmaonseverallevels•generallyexperienceagreaterburdenofmorbidity andmortalitythantheoverallpopulation.

Why do they smoke more?Researchersbelievethatacombinationofbiological,psychologicalandsocialfactorscontributetoincreasedtobaccouseamongpersonswithmentalillnesses.

Biological predispositionPersonswithmentalillnesseshaveuniqueneurobiologicalfeaturesthatmayincreasetheirtendencytousenicotine,makeitmoredifficulttoquitandcomplicatewithdrawalsymptoms.

Nicotineaffectstheactionsofneurotransmitters(e.g.dopamine).Forexample,peoplewithschizophreniawhousetobaccomayexperiencelessnegativesymptoms(lackofmotivation,driveandenergy).

Nicotineenhancesconcentration,informationprocessingandlearning.(Thisisespeciallyimportantforpersonswithpsychoticdisordersforwhomcognitivedysfunctionmaybeapartoftheirillnessorasideeffectofantipsychoticmedications).

Otherbiologicalfactorsincludenicotine’spositiveeffectsonmood,feelingsofpleasureandenjoyment.

Someevidencesuggeststhatsmokingisassociatedwithareducedriskofantipsychotic-inducedParkinsonism.

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Tobacco use and mental illness

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Psychological considerations•Tobaccousemaytemporarilyrelievefeelings oftensionandanxietyandisoftenusedtocope withstress.•Peopledevelopadailyroutineofsmoking.

Social considerations•Peoplemaysmoketofeel“partofagroup.”•Smokingisoftenassociatedwithsocialactivities.•Personswithmentalillnessesmaynothavealot ofactivitiestokeepthembusy.Whenthey’re bored,theymaysmokemore.•Thesiteofasocialactivitymaysupport tobaccouse.

Stigma•Providersoftenthinkthatpeoplewithmental illnessesareunabletoquitsmoking.•Symptommanagementoftentakesprecedence overpreventivehealthmeasures.

Specific mental disordersWhataresomeconsiderationsforsmokingcessationinregardtospecificmentaldisorders?

DepressionAmongpatientsseekingsmokingcessationtreatment,25-40percenthaveahistoryofmajordepressionandmanyhaveminordysthymicsymptoms.

Depressionhasbeenshowntopredictpoorersmokingcessationrates.Considerstartingorrestartingpsychotherapyorpharmacotherapyfordepressioninpatientswhostatethatdepressionintensifiedwithcessationorthatcessationcauseddepression.

Cognitivebehavioraltherapyfordepressionandantidepressantshasbeenfoundtoimprovesmokingcessationratesinthosewithahistoryofdepressionorsymptomsofdepression.

Forasmokerwithahistoryofdepressioncurrentlytakingantidepressantmedication,itisimportanttonotethatsomeantidepressantlevelswillincreasewithsmokingcessation.

Stress is a big trigger for me. I don’t know how to deal with stress.

– Cathi, age 32

What I did to keep from craving cigarettes for a while is just to keep busy, being with people, and talking and playing games and working and things like that. That’s what helped me.

– Robert, age 43

SchizophreniaPersonswithschizophreniawhosmokemaybelessinterestedintobaccocessation,makingstrategiestoenhancemotivationtoquitespeciallyimportant.

Whenmentalhealthconsumerswithschizophreniadotrytostop,manyareunsuccessful;thus,intensivetreatmentsareappropriateevenwithearlyattempts.

Thehighprevalenceofalcoholandillicitdrugabuseinconsumerswithschizophreniacaninterferewithsmokingcessation.

Thebloodlevelsofsomeantipsychoticscanincreasedramaticallywithcessation.Nicotinewithdrawalcanmimictheakathisia,depression,difficultyconcentratingandinsomniaseeninconsumerswithschizophrenia.

Other psychiatric disordersThereisinsufficientinformationtomakespecificrecommendationsabouttailoringtreatmentofsmokingcessationtotheneedsofsmokerswithotherpsychiatricdisorders.

Ingeneral,whenmentalhealthconsumersmakeanattemptatsmokingcessation,theyshouldbefollowedcloselytomonitorformoreseverenicotinewithdrawal,exacerbationoftheirpsychiatricdisorderandpossiblesideeffectsduetocessation-inducedincreasesinmedicationlevels.

Methylphenidate(Ritalin)andd-amphetamine(Dexedrine),stimulantscommonlyprescribedforbehavioralproblemsassociatedwithattentiondeficithyperactivitydisorder(ADHD)increaseratesofsmokingandthereinforcingeffectsofsmoking.Methylphenidateandd-amphetamineuseinearlylifeleadstoincreasedoddsofdailysmokinglaterinlife.

Tobacco industry targetingBy1977,smokerswerebecominga“downscalemarket.”RJReynoldsnotedthatlesseducated,lowerincome,minoritypopulationsweremoreimpressionable/susceptibletomarketingandadvertising.Tobaccocompaniesbegantargetingthesepopulations.Free cigarettes were distributed to homeless shelters, mental hospitals and homeless service organizations.Cigaretteswerepurchasedforthementallyillandhomelesssothatconsumerswouldsmoke“clean”cigarettes,notdirtycigarettesbutts.

Thetobaccoindustryhastargetedpsychiatrichospitalsforsalespromotionsandgiveaways.Theyhavemadefinancialcontributionstohomelessveteranorganizations,usingrelationshipstoadvancetheirpoliticalagenda.

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I’ve been schizophrenic since I was 14. I was told more less when I went to the hospitals that cigarettes help control certain areas in my brain and the way we function out in society. I more or less became more of a smoker because I was told it would help me with my illness. I was taught more about it helping my illness than I was about cancer and stuff like that. – Marc, age 24

Readiness to quit and stages of changeTheStagesofChangeModel(alsoknownastheTranstheoreticalModel)illustratedbelowisusefulinrecognizingthatnicotinedependenceisachronic,relapsingdisorderwithmosttobaccousersinthegeneralpopulationrequiringfivetosevenattemptsbeforetheyfinallyquitforgood.Manypatientsdonotrealizethatitusuallytakesseveralattemptstostopusingtobaccoandwillneedmotivationtoattempttoquitiftheyhavebeenunsuccessfulinthepast.Itisusefultothinkoftobaccocessationasaprocessratherthananevent.

Onceapersonhasbeenidentifiedasatobaccouser,hisorherreadinesstoquitcanbedetermined.Thisisimportantbecausetobaccouserswhoarenotconsideringquittingappeartoneeddifferentinterventionsthanthosewhoareambivalentaboutquittingorthosepresentlyinterestedinquitting.TobaccousersinthePrecontemplationstage(notconsideringquitting)canbemovedtotheContemplationstagebyaskingconsumerstoconsiderthenegativeconsequencesoftobaccouseforthemandtheadvantagesoftobaccocessation(thisinformationhastobepersonalized).Itisworthwhiletoactivelyencouragequittingandoffersupportandtreatmentaswellasconveyingthemessagethatpersonswithmentalillnessescansuccessfullyquitusingtobacco.

Stages of change•Precontemplation:Nochangeisintendedinthe foreseeablefuture.Theindividualisnotconsidering quitting.•Contemplation:Theindividualisnotpreparedtoquitat present,butintendstodosointhenextsixmonths.•Preparation:Theindividualisactivelyconsidering quittingintheimmediatefutureorwithinthenext month.•Action:Theindividualismakingovertattemptstoquit. However,quittinghasnotbeenineffectforlongerthan sixmonths.•Maintenance:Theindividualhasquitforlongerthan sixmonths.

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Assessment and intervention planning

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The 5 A’s: Ask, Advise, Assess, Assist and ArrangeTheU.S. Public Health Service Clinical Practice Guideline: Treating Tobacco Use and Dependenceprovideshealthcarecliniciansastrategyforsmokingcessationtreatmentthatisbuiltaroundthe“5A’s”(Ask,Advise,Assess,AssistandArrange).Knowingthatprovidershavemanycompetingdemands,the5A’swerecreatedtokeepstepssimple.

Onthefollowingpagesyouwillfindasummaryoftheseeasilyimplementedsteps.

TheGuidelinerecommendsthatallpeopleenteringahealthcaresettingshouldbeaskedabouttheirtobaccousestatusandthatthisstatusshouldbedocumented.Providersshouldadvisealltobaccouserstoquitandthenassesstheirwillingnesstomakeaquitattempt.Personswhoarereadytomakeaquitattemptshouldbeassistedintheeffort.Followupshouldthenbearrangedtodeterminethesuccessofquitattempts.

Thefull5A’smodelismostappropriateforagenciesandorganizationsthathavetobaccocessationmedicationsand/orbehavioralservicesavailableforconsumers.Foragenciesandorganizationsthatdonothavetobaccocessationservicesreadilyavailable,werecommendtheuseofthefirsttwoA’s(askandadvise)andthenrefertoavailablecommunityservices.Thefull5A’smodel,aswellastheabbreviatedask-advise-refermodelarepresentedintheflowchartandtablesatthebackofthisbook.

A S K

AD

VI S

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AS

SESSASSIS

T

AR

RA

NG

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Tobacco dependenceand use (current or former)

is a chronic relapsingcondition that requires

repeated interventions and a systematic approach.

If you have limited time:ASK ADVISE REFER

Strategies for Implementation

Clear:“Asyourclinician,Iwanttoprovideyouwithsomeeducationabouttobaccouseandencourageyoutoconsiderquittingtoday.”

Strong:“Asyourclinician,Ineedyoutoknowthatquittingsmokingisthemostimportantthingyoucandotoprotectyourhealthnowandinthefuture.TheclinicstaffandIwillhelpyou.”

Personalized:Tietobaccousetocurrenthealth/illness,itssocialandeconomiccosts,motivationlevel/readinesstoquit,and/ortheimpactoftobaccouseonchildrenandothersinthehousehold.

Seepatienteducationalbrochureatbackofthismanual.

Action

Inaclear, strong andpersonalizedmanner, adviseeverytobaccousertoquit.

Bemindfultoadviseinanon-judgmentalmanner.

Action

Forconsumersinterestedinquitting.

Strategies for Implementation

Provideinformationonlocalsmokingcessationresources.Youmayfindlocalresourcesathttp://www.co.quitnet.com/libraries/programs/.

Useproactivereferralifavailable:RequestwrittenconsumerpermissiontofaxtheircontactinformationtotheColoradoQuitLineorotherprogram.Informthepatientthecessationprogramstaffwillcontactthem.

Documentthereferral.

SeeColoradoQuitLinefaxreferralformatendofthissection.

Action

Askeveryconsumerateveryvisit,includinghospitaladmissions,iftheysmoke.

Strategies for Implementation

Withinyourpractice,systematicallyidentifyalltobaccousersateveryvisit.

Establishanofficesystemtoconsistentlyidentifytobaccousestatusateveryvisit.(Seeclinicexampleatendofthissection.)

Determinewhatformoftobaccoisused.

Determinefrequencyofuse.

Determinetobaccousestatus.

Makenoteofconsumersexposedtosecondhandsmoke.

Actions and Strategies for Mental Health Providers to Help Consumers Quit Smoking

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ASK

REFER

ADVISE

Action

Assesswillingnesstomakeaquitattemptwithinthenext30days.

Determinewiththepatientthecostsandbenefitsofsmokingforhimorher.

Determinewherethepatientisintermsofthereadinesstochangemodel.

Assesspastquitattemptsandpast/currentpsychiatricsymptomsforconsumerswantingtoquit.

Strategies for Implementation

Assessreadinessforchange.Gotop.7tolearnhowtoassessreadinessforchange.

Iftheconsumerisreadytoquit,proceedtoAssist(below)and/orarrangeformoreintensiveservicestohelpwiththequittingprocess.

Iftheconsumerwillparticipateinanintensivetreatment,deliversuchatreatmentorrefertoanintensiveintervention(Arrange).

Iftheconsumerisn’treadytoquit,don’tgiveup.Providerscangiveeffectivemotivationalinterventionsthatkeepconsumersthinkingaboutquitting.Conductamotivationalinterventionthathelpsconsumersidentifyquittingaspersonallyrelevantandrepeatmotivationalinterventionsateveryvisit.

Foraddressingtobaccocessationwithtobaccousersunwillingtoquit,pleaseproceedtothe5R’sonpage12.

Fortheconsumerwhoiswillingtoquit:

Obtainasmokinghistoryandassessexperiencewithpreviousquitattempts:• Reasonsforquitting.• Anychangeinpsychiatricfunctioningwhenheorshetriedtostop?• Causeofrelapse(wasthisduetowithdrawalsymptomsorincreased psychiatricsymptoms?)• Howlongdidheorsheremainabstinent?• Priortreatmentintermsoftype,adequacy(dose,duration),complianceand consumer’sperceptionofeffectiveness.• Expectationsaboutfutureattemptsandtreatments.

Determinewhetherthereareanypsychiatricreasonsforconcernaboutwhetherthisisthebesttimeforcessation:• Istheconsumerabouttoundergoanewtherapy?• Istheconsumerpresentlyincrisis,oristhereaproblemthatissopressingthat timeisbetterspentonthisproblemthanoncessationatthisvisit?

• Whatisthelikelihoodthatcessationwouldworsenthenon-nicotinepsychiatric disorder?Andcanthatpossibilitybediminishedwithfrequentmonitoring,useof nicotinereplacementtherapyorothertherapies?

• Whatistheconsumer’sabilitytomobilizecopingskillstodealwithcessation? Ifthecopingskillsarelow,wouldtheconsumerbenefitfromindividualorgroup behaviortherapy?

• Istheconsumerhighlynicotinedependentordoestheconsumerhaveahistory ofrelapseduetowithdrawalsymptomsorincreasedpsychiatricsymptoms?Ifso, whichmedicationmightbeofhelp?

Increasingreadiness/motivation:Ifaconsumerwithpsychiatricillnessisnotreadytomakeaquitattempt,enhancemotivationanddealwithanticipatedbarrierstocessation.• Useproblemsolvingstrategies.• Increasemonitoringoftobaccouse.• Employbehavioraltherapyand/ornicotinereplacementtherapy.• Addressfearsofwithdrawalsymptomsorofworseningpsychiatricproblems.

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ASSESS

Action

Helptheconsumerwithaquitplan.

Recommenduseofapprovednicotinereplacementtherapy(NRT)and/orcounseling

Strategies for Implementation

Set a quit date,ideallywithintwoweeks.

Tellfamily,friendsandcoworkersaboutquittingandrequestunderstandingandsupport.

Anticipatetriggersorchallengestoplannedquitattempt,particularlyduringthecriticalfirstfewweeks.Theseincludenicotinewithdrawalsymptoms.Discusshowtheconsumerwillsuccessfullyovercomethesetriggersorchallenges.

Removetobaccoproductsfromtheenvironment.Priortoquitting,consumershouldavoidsmokinginplaceswheretheyspendalotoftime(e.g.work,home,car).

Forconsumerswithcognitivedifficulties(e.g.memoryorattentiondeficits)duetomentalillness,havethemwritedowntheirquitplan,sotheycanrefertoitlater.

RecommendtheuseofNRTmedicationstoincreasecessationsuccess.Discussoptionsforaddressingbehavioralchanges(e.g.cessationclasses,individualcounseling,telephonecoachingfromtheColoradoQuitLine)Encouragepatientswhoarereadytoquitthattheirdecisionisapositivestep.

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ASSIST

Action

Schedulefollow-upcontact.

Strategies for Implementation

Timing.Followupcontactshouldoccursoonafterthequitdate,preferablywithinthefirstweek.Asecondfollow-upcontactisrecommendedwithinthefirstmonth.Schedulefurtherfollow-upcontactsasneeded.

Actionsduringfollow-upcontact:

Congratulate success!

Iftheconsumerhasrelapsed,reviewthecircumstancesandelicitrecommitmenttototalabstinence.• Remindpatientthatalapsecanbeusedasalearningexperience.• Identifyproblemsalreadyencounteredandanticipatechallengesinthe immediatefuture.• AssessNRTuseandproblems.• Consideruseorreferraltomoreintensivetreatment.• Give positive feedback about the patient’s attempts to quit. Individuals often cut down substantially on their tobacco use before quitting, and this harm reduction needs to be recognized and congratulated.

ARRANGE

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The 5 R’s: Addressing Tobacco Cessation for the Tobacco User Unwilling to Quit(From Treating Tobacco Use and Dependence. Quick Reference Guide for Clinicians, October 2000. U.S. Public Health Service. www.surgeongeneral.gov/tobacco/tobaqrg.htm)

The“5R’s”Relevance,Risks,Rewards,RoadblocksandRepetition,aredesignedtomotivatesmokerswhoareunwillingtoquitatthistime.

Smokersmaybeunwillingtoquitduetomisinformation,concernabouttheeffectsofquittingordemoralizationbecauseofpreviousunsuccessfulquitattempts.Therefore,afteraskingabouttobaccouse,advisingthesmokertoquitandassessingthewillingnessofthesmokertoquit,itisimportanttoprovidethe“5R’s”motivationalintervention.

RelevanceEncouragetheconsumertoindicatewhyquittingispersonallyrelevant,asspecificallyaspossible.Motivationalinformationhasthegreatestimpactifitisrelevanttoaconsumer’smedicalstatusorrisk,familyorsocialsituation(e.g.,havingchildreninthehome),healthconcerns,age,genderandotherimportantpatientcharacteristics(e.g.,priorquittingexperience,personalbarrierstocessation).

RisksAsktheconsumertoidentifypotentialnegativeconsequencesoftobaccouse.Suggestandhighlightthosethatseemmostrelevanttothem.Emphasizethatsmokinglow-tar/low-nicotinecigarettesoruseofotherformsoftobacco(e.g.,smokelesstobacco,cigarsandpipes)willnoteliminatetheserisks.

Examplesofrisksare:

•Acuterisks:Shortnessofbreath,exacerbationof asthma,harmtopregnancy,impotence,infertility andincreasedserumcarbonmonoxide.

•Longtermrisks:Heartattacksandstrokes,lung andothercancers(larynx,oralcavity,pharynx, esophagus,pancreas,bladder,cervix),chronic obstructivepulmonarydiseases(chronicbronchitis andemphysema),longtermdisabilityandneed forextendedcare.

•Environmentalrisks:Increasedriskoflungcancer andheartdiseaseinspouses;higherratesof smokinginchildrenoftobaccousers;increased riskforlowbirthweight,SuddenInfantDeath Syndrome,asthma,middleeardiseaseand respiratoryinfectionsinchildrenofsmokers.

Every time I need a pack of cigarettes, that’s taking money out of my pocket. You can see everybody around here, people that aren’t smoking, look how much money they have. People that are smoking are pretty much broke. If I could quit smoking, I’d have more money to spend.

– James, age 37

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RewardsAsktheconsumertoidentifypotentialbenefitsofstoppingtobaccouse.Suggestandhighlightthosethatseemmostrelevanttotheconsumer.

Examplesofrewardsfollow:• Improvedhealth•Foodtastesbetter• Improvedsenseofsmell•Moneysaved•Betterselfimage•Home,car,clothing,breathsmellbetter•Nomoreworryingaboutquitting•Setagoodexampleforchildren•Havehealthierbabiesandchildren•Nomoreworryingaboutexposingothers tosmoke•Feelbetterphysically•Performbetterinphysicalactivities•Reducewrinkling/agingofskin

RoadblocksAsktheconsumertoidentifyimpedimentstoquittingandnoteelementsoftreatment(problemsolving,medications)thatcouldaddressbarriers.

Typicalbarriersmightinclude:•Withdrawalsymptoms•Fearoffailure•Weightgain•Lackofsupport•Depression•Enjoymentoftobacco

RepetitionRepeatmotivationalinterventionseverytimeanunmotivatedconsumervisitstheclinicsetting.Tobaccouserswhohavefailedinpreviousquitattemptsshouldbetoldthatmostpeoplemakerepeatedquitattemptsbeforetheyaresuccessful.

Cultural ConsiderationsCulturalissuesshouldalsobeconsideredforthoseindividualsofdiverseracialandethnicbackgroundsastobaccocessationassessmentandservicesareoffered.

RecommendationsKeyfindingsfromtheSurgeonGeneral’sreport:(1998SurgeonGeneral’sReport,TobaccoUseAmongU.S.Racial/EthnicMinorityGroups)

Inthefourracial/ethnicgroupsstudied(AfricanAmerican,AmericanIndian/AlaskaNative,AsianAmerican/PacificIslanderandHispanic),AfricanAmericanmenbearoneofthegreatesthealthburdens,withdeathratesfromlungcancerthatare50percenthigherthanthoseofCaucasianmen.

Ratesoftobaccorelatedcancers(otherthanlungcancer)varywidelyamongmembersofracial/ethnicgroups.TheyareparticularlyhighamongAfricanAmericanmen.

Tobaccouseamongadolescentsfromracialandethnicminoritygroupshasbeguntoincreaserapidly,threateningtoreversetheprogressmadeagainstlungcanceramongadultsintheseminoritygroups.CigarettesmokingamongAfricanAmericanteenshasincreased80percentoverthelastsixyears–threetimesasfastasamongwhiteteens.

Thehighleveloftobaccoproductadvertisinginracial/ethnicpublicationsisproblematicbecausetheeditorsandpublishersofthesepublicationsmaylimittheleveloftobaccousepreventionandhealthpromotioninformationincludedintheirpublications.

Well, the first thing is you have to decide is that you’re really committed to doing it and then you try over and over and over until you finally get there, and eventually you get there. But it takes a lot of time and it’s not easy.

– Sandy, age 37

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Recommendations for Mental Health CliniciansWhenworkingwithpersonswithmentalillnesseswhoarealsoofdiverseracial/ethnicbackgrounds,thementalhealthclinicianshould:

•Ask,Advise,Assistand/orReferallpatientswithregardtotobaccocessation.Thereisacriticalneedto delivereffectivetobaccodependenceeducationandinterventionstoethnicandracialminoritieswith mentalillnesses.

•Usecessationinterventionsthathavebeeneffectiveforpersonswithmentalillnesses(e.g.NRTorbuproprion incombinationwithindividualorgroupcounselingthatemploysmotivationalinterviewingorcognitive- behavioralstrategies).Avarietyofsmokingcessationinterventions(includingscreening,clinicianadvice, self-helpmaterialsandthenicotinepatch)havebeenproveneffectivefortobaccocessationinminority populations.

•Beculturallyappropriate,reflectingthetargetedracial/ethnicgroups’culturalvalues.Thismayincreasethe smoker’sacceptanceoftreatment.

•Conveycessationcounselingorself-helpmaterialsinalanguageunderstoodbythesmoker.

ResourcesFormoreinformationabouttobaccouseandinterventionforracial/ethnicpopulationsinColorado,pleaseseethefollowingonlineresources:

ColoradoTobaccoDisparitiesStrategicPlanningWorkingGroup:http://ctdsp.amc.org/

ColoradoStateStateTobaccoEducationandPrevention(STEPP):http://steppcolorado.com

ColoradoMinorityHealthForumforInformationonReducingHealthDisparitiesinColorado:http://www.coloradominorityhealthforum.org/

Example for Clinic Screening for Tobacco Use

From the U.S. Department of Health & Human Serviceshttp://www.surgeongeneral.gov/tobacco/tobaqrg.pdf

ACTION STRATEGIESforIMPLEMENTATION

Implementanoffice-widesystem Expandvitalsignstoincludetobacco thatensuresthat,foreverypatientat useoruseanalternativeuniversal everyclinicvisit,tobacco-usestatus identificationsystem. isqueriedanddocumented.

VITALSIGNS

BloodPressure:

Pulse: Weight:

Temperature: RespiratoryRate:

TobaccoUse(circleone):CurrentFormerNever

• Repeatedassessmentisnotnecessaryinthecaseoftheadultwhohasneverused tobaccoorhasnotusedtobaccoformanyyears,andforwhomthisinformationis clearlydocumentedinthemedicalrecord.

• Alternativestoexpandingthevitalsignsaretoplacetobacco-usestatusstickerson allpatientchartsortoindicatetobacco-usestatususingelectronicmedicalrecords orcomputerremindersystems.

Key findingsSmokingcessationmodelsforpersonswithmentalillnessesgenerallycombinenicotinereplacementtherapy(NRT)withCognitiveBehavioralTherapy(CBT),atypeofpsychotherapythatfocusesonchangingdysfunctionalthoughts,emotionsandbehavior.

CBTprogramsthatproducethemostsuccessfulquitratesforthementalhealthpopulationgenerallyhavegroupsofapproximately8-10individualsthatmeetonceaweekfor7-10weeks.

ConsumerswithschizophreniaseemtohavethehighestsuccesswhenCBTiscombinedwithNRTandstrategiestoenhancemotivation.ArandomizedcontrolstudybyBakeretal.(2006)foundthatatallfollow-upperiods,asignificantlyhigherproportionofsmokerswithapsychoticdisorderwhocompletedalltreatmentsessionswerecurrentlyabstinent,relativetoacomparisongroupofpersonsreceivingcareasusual,(pointprevalencerates:3months,30.0%vs.6.0%;6months,18.6%vs.4.0%;12months18.6%vs6.6%).Smokerswhocompletedalleighttreatmentsessionswerealsomorelikelytohaveachievedcontinuousabstinenceatthreemonths(21.4%vs.4.0%).

Thereisastrongdose-responserelationbetweenthesessionlengthofperson-to-personcontactandsuccessfultreatmentoutcomes.Intensiveinterventionsaremoreeffectivethanlessintensiveinterventionsandshouldbeusedwheneverpossible.

Haugetal.(2005)foundthatforpeoplewithdepression,smokingcessationwasbestpredictedbystageofchange,withthoseinpreparationenteringtreatmentmorequicklythancontemplatorsorprecontemplators.Thevariablesmostassociatedwithacceptingtreatmentwerenotseverityofsymptoms,butrathercurrentuseofpsychiatricmedicationsandperceivedabilitytosucceedinquitting.

S M O K I N G C E S S A T I O N T R E A T M E N T | 1 5

Smoking cessation treatment for persons with mental illnesses

S M O K I N G C E S S A T I O N T R E A T M E N T | 1 6

Components of Successful Intensive Intervention Programs:Intensivecessationinterventionsshouldincludethefollowing(fromtheU.S.DepartmentofHealthandHumanServices,2000):

AssessmentAssessmentsshouldensurethattobaccousersarewillingtomakeaquitattemptusinganintensivetreatmentprogram.Otherassessmentscanprovideinformationusefulincounseling(e.g.stresslevel,presenceofpsychiatricsymptoms,stressors,othercomorbidity).Personswithmentalillnesseswhoareattemptingtoquitsmokingshouldbecarefullyassessedandmonitoredfordepressionandotherpsychiatricsymptomsateveryofficevisit.

Program clinicians Multipletypesofcliniciansareeffectiveandshouldbeused.Onecounselingstrategywouldbetohaveamedical/healthcarecliniciandelivermessagesabouthealthrisksandbenefitsanddeliverpharmacotherapy,andbehavioralhealthcliniciansdeliveradditionalpsychosocialorbehavioralinterventionslikecognitivebehavioraltherapy(CBT).

Program intensity Becauseofevidenceofastrongdose-responserelationship,theintensityoftheprogramshouldbe:•Sessionlength–longerthan10minutes.•Numberofsessions–4ormore.•Totalcontacttime–longerthan30minutes.

Program formatEitherindividualorgroupcounselingmaybeused.Proactivetelephonecounselingalsoiseffective.Useofadjuvantself-helpmaterialisoptional.Follow-upassessmentinterventionproceduresshouldbeused.

Type of counseling and behavioral therapies Counselingandbehavioraltherapiesshouldinvolvepracticalcounseling(problemsolving/skillstraining),aswellasintra-treatmentandextra-treatmentsocialsupport.

PharmacotherapyEverysmokershouldbeencouragedtousepharmacotherapies,exceptinthepresenceofspecialcircumstances.Specialconsiderationshouldbegivenbeforeusingpharmacotherapywithselectedpopulations(e.g.pregnancy,adolescents).Theclinicianshouldexplainhowthesemedicationsincreasesmokingcessationsuccessandreducewithdrawalsymptoms.Thefirst-linepharmacotherapyagentsinclude:bupropionSR,nicotinegum,nicotineinhaler,nicotinenasalsprayandthenicotinepatch.(SeePharmacotherapiesSectiononp.19andlaminatedsheetatbackofthismanual).

S M O K I N G C E S S A T I O N T R E A T M E N T | 1 7

Behavioral Interventions for Smoking CessationUseofbriefpsychosocialinterventions,self-helpandsupportivetherapyhavebeenshowntobeeffectivewithgeneralmedicalpatientsbutmaynotbesufficientforconsumerswithpsychiatricproblems(APA,1996).Additionally,peoplewithmentalillnessesoftenhavefewersocialsupportsandcopingskills.Therefore,intensivebehavioraltherapyshouldbeconsideredforthesepeopleevenintheearlyquitattempts.Whenpossible,thementalhealthprovidershouldelicitconsumerpreferencesaboutgrouporindividualtherapy.Ifaconsumerhasaspecificissuethatmightunderminetobaccocessation(e.g.problemswithassertiveness),thementalhealthprovidermightworkonthisissueinindividualtherapywhiletheconsumeralsoattendsgrouptherapyfortobaccocessation.

Cessationprogramsforpeoplewithmentalillnessesincludeabout7-10sessions.Typically,thereis• anintroductiontotobaccohistoryandprevalence ofuse•educationaboutthepropertiesofnicotine,health effectsofnicotineandaddictivenatureofnicotine• areviewofthereasonswhypeoplesmoke•educationaboutwaysonecanquitsmoking,use ofmedicationanddevelopmentofaquitplan.

Asnotedabove,additionalsessionsareusefulforaddressingissuesthatarepertinenttopersonswithmentalillnesses(i.e.,developingcopingskillsforstressandanxiety).

TheSANEprograminAustralia(Strasser,2001)isoneeffectivegroupcounselingprogramforpersonswithschizophrenia.Itinvolvesteachingproblemsolvingskillsandcognitive-behavioraltechniquestoaidsmokingreductionandcessationmaintenance.Thegroupconsistsof10sessions,runbytwotrainedfacilitators.Thecontentconsistsofthefollowing:• IntroductiontotheProgram•ReasonstoQuit•BenefitsofQuitting•UnderstandingWhyWeSmokeandWays ofQuitting•WithdrawalSymptoms•SocialSupport•DealingwithStressandAnxiety•CopingwithDepression•AssertivenessTraining•AngerManagement•Smoke-FreeLifestyle•DealingwithHighRiskSituations

More Elements of Successful CounselingFurtherelementsofsuccessfulcounselingandsupportiveinterventionsareoutlinedinthefollowingtables(U.S.DepartmentofHealthandHumanServices,2000).

Practical counseling treatment component (problems solving/skills training

Recognizedangersituations:Identifyevents,stressors,internalstatesoractivitiesthatincreasetheriskofsmokingorrelapse.

Developcopingskills:Identifyandpracticecopingorproblemsolvingskills.

Providebasicinformationaboutsmokingandsuccessfulquitting.

Examples

NegativemoodPsychiatricsymptomsBeingaroundothersmokersDrinkingalcoholorusingdrugsExperiencingurgesBeingundertimepressure

Learningtoanticipateandavoidtemptation.Learningcognitivestrategiesthatwillreducenegativemoods.Accomplishinglifestylechangesthatreducestress,improvequalityoflifeorproducepleasure.Learningcognitiveandbehavioralactivitiestocopewithsmokingurges(e.g.distractingattention).

Anysmoking(evenasinglepuff)increasesthelikelihoodofafullrelapse.Withdrawaltypicallypeakswithin1-3weeksafterquitting.Withdrawalsymptomsincludenegativemood,urgestosmokeanddifficultyconcentrating.Informationontheaddictivenatureofsmoking.

Common elements of practical counseling

S M O K I N G C E S S A T I O N T R E A T M E N T | 1 8

Additionally, staff and peer support are key factors in cessation counseling. Some common elements of each:

Supportive treatment component

Encouragethepatientinthequitattempt.

Communicatecaringandconcern.

Encouragetheconsumertotalkaboutthequittingprocess.

Examples

Sharethateffectivetobaccodependencetreatmentsarenowavailable.Notethatone-halfofallpeoplewhohaveeversmokedhavenowquit.Communicatebeliefintheconsumer’sabilitytoquit.

Askhowtheconsumerfeelsaboutquitting.Directlyexpressconcernandwillingnesstohelp.Beopentotheconsumer’sexpressionoffearsofquitting,difficultiesexperiencedandambivalentfeelings.

Askabout:Reasonstheconsumerwantstoquit.Concernsorworriesaboutquitting.Successtheconsumerhasachieved.Difficultiesencounteredwhilequitting.

Common elements of eliciting peer support and other resources

S M O K I N G C E S S A T I O N T R E A T M E N T | 1 9

Supportive treatment component

Trainconsumersinsupportsolicitationskills.

Promptsupportseeking.

Arrangeoutsidesupport.

Examples

Showvideotapesthatmodelskills.Practicerequestingsocialsupportfromfamily,friendsandcoworkers.Aidconsumerinestablishingasmoke-freehome.

Helpconsumeridentifysupportiveothers.Calltheconsumertoremindhimorhertoseeksupport.Informconsumersofcommunityresourcessuchasquitlines.

Mailletterstosupportiveothers.Callsupportiveothers.Inviteotherstocessationsessions.Assignconsumerstobe“buddies”foroneanother.

Prescribing Cessation MedicationsUtilizethefrequencyofmentalhealthtreatmentvisitsasanopportunityformonitoringprogressinsmokingcessation.Additionally,smokingcessationstrategiesshouldbeintegratedandcoordinatedwithtreatmentsformentalillnesses.

Sincepeoplewithmentalillnessesappeartohavemorewithdrawalsymptomswhentheystopsmokingthanthegeneralpopulation,theuseofnicotinereplacementtherapy(NRT)eveninearlycessationattemptsisrecommended.

TheoptimaldurationofNRTisnotknown.Someindividualsappeartorequirelong-termuseofNRT(e.g.,≥6months),butalmostallindividualseventuallystopusingNRTandthedevelopmentofdependenceonNRTisrare.Thus,patientpreferenceshouldbethemajordeterminateforthedurationofNRT(American Psychiatric Association Practice Guidelines 2006: Treatment of Patients with Substance Use Disorders,2ndEdition,p54).

Cliniciansshouldcloselymonitoractionsorsideeffectsofpsychiatricmedicationsinsmokersmakingquitattempts.

DepressionConsiderbuproprionandnortriptylineforconsumerswithdiagnosesofdepression.Bupropion-SRhasbeendemonstratedtobethemosteffectiveindepressedpatients.Patientswhousebupropion-SRduringasmokingcessationprogramaremorelikelytobeabstinentatthequitdate.However,relapseishighfollowingthediscontinuationoftreatment(Evins,etal.,2005;George,etal.,2002).Additionally,bupropion-SRhashadadverseaffectsonpatientswithbipolardisorderand/orahistoryofeatingdisorders.Itshouldnotbeusedinthesepopulations(McNeill,2004).Additionalresearchonsmokerswithahistoryofdepressionsuggeststheusefulnessofthenicotinetransdermalpatch(Thorsteinssonetal.,2001)andnicotinegum(Kinnunenetal.,1996)forshort-termsmokingcessation.

StronglyconsiderbehavioraltherapiessuchasCognitiveBehavioralTherapy(CBT),assmokerswithdepressionarelikelytofailwithmoreminimalinterventions(Brownetal,2001).ImprovedcessationoutcomeswiththeadditionofCBThavebeenreportedfornortriptylineandnicotinegum(Halletal.,1998,1994).

S M O K I N G C E S S A T I O N T R E A T M E N T | 2 0

SchizophreniaSmokingcessationprogramsthatusethenicotinetransdermalpatch(NTP)demonstratethehighestquitratesforpatientswithschizophrenia(Williams&Hughes,2003)asitaidsinwithdrawalsymptoms.WhentreatmentincludestheuseofNRTinpatientswithschizophrenia,Dalacketal.(1999)foundthatdyskinesiasdecreasedduringabstinenceintheplacebopatchcondition,butincreasedduringabstinenceintheactivepatchcondition.

NRTisassociatedwithsmokingcessationratesof27percentto42percentinsmokerswithschizophrenia(Addingtonetal.,1998;Chouetal.,2004;Georgeetal.,2000).Also,useofnicotinenasalspray,whichproducesthehigherplasmalevelsofnicotine,isassociatedwiththereductionofwithdrawalandcraving(Williamsetal.,2004).

Incontrolledtrials,pharmacologicaltreatmentwithsustained-release(SR)bupropionhasbeenefficaciousinpromotingabstinenceinpersonswithschizophrenia.Treatment-seekingsmokershaveshownsuccess(withshort-termabstinenceratesof11percentto50percent)withacombinationofbupropionSRandcognitive-behavioraltherapy(CBT)atboththe150mg/day(Evinsetal.,2001)andthe300mg/daydoses(Evinsetal.,2005;Gerogeetal.,2002).Bupropiontreatmentalsoseemstoreducethenegativesymptomsofschizophrenia(Weinberberetal.,2006).

Patientstreatedwithatypicalantipsychoticagents,suchasclozapine(Clozaril),smokeless(Georgeetal.,1995;McEvoyetal.,1999,1995)andhaveaneasiertimequitting(Georgeetal.,2002,2000)thanthosetreatedwithtypicalantipsychoticmedications.However,smokingcessationcancauseachangeinplasmaconcentrationsofpsychotropicagentsduetoadecreaseintheinductionofcytochromeP4501A2(Weinbergeretal.2006).Antipsychoticmedicationswhosemetabolismisaffectedbysmokinginclude:clozapine(Clozaril),fluphenazine

(Modecate),haloperidol(Haldol),andolanzapine(Zyprexa).Therefore,monitoringmedicationsideeffectsmaybeneededduringthefirstmonthafterquitting(Kalmanetal.,inpress;ZiedonisandGeorge,1997).Themetabolismofrisperidone(Risperdal)andquetiapine(Seroquel)doesnotappeartobeaffectedbysmoking(Strasser,2001).

Bipolar DisorderGlassmanetal.(1993)foundthatpersonswithbipolardisorder(BD)mayalsobeatriskforrecurrenceofdepressivesymptomsduringsmokingcessation.Interestingly,personswithBDshowageneticlinkagetothea7nAChRnicotinicreceptorlocusonchromosome15similartothatfoundforpersonswithschizophrenia(Leonardetal.,2001).Todate,therehavebeennoempiricallybasedtreatmentspublishedforsmokerswithBD(Weinberger,etal,2006).UseofNTPissuggestedforthispopulation.

Anxiety DisordersAlthoughpatientsreportthatsmokingreducesdepressionandanxiety,chronicnicotineuseinanimalstudiesispositivelycorrelatedwithincreasedanxiety(Irvineetal.2001).Itisuncleartowhatextentsmokersexperiencewithdrawalsymptomsandmisinterpretareductioninnicotinewithdrawalasanxietyrelief(ZiedonisandWilliams,2003).Cinciripiniandcolleagues(1995)foundthatsmokerswithhighlevelsoftraitanxietyreceivingbuspirone(BuSpar)versusplaceboweremorelikelytohaveremainedabstinentattheendofthetrialbutnotatfollow-up.AsnotedbyWeinbergeretal.,(2006),aplacebo-controlledstudybyHertzbergetal.(2001)ofbupropionSRforsmokerswithposttraumaticstressdisorder(PTSD)foundthatbupropionwaswelltoleratedandresultedinhigherratesofsmokingcessation(60percent)ascomparedtotheplacebo(20percent).

S M O K I N G C E S S A T I O N T R E A T M E N T | 2 1

Also,inastudyofveteranswithpost-traumaticstressdisorderwhoweresmokersMcFallandcolleagues(2005)foundthatsmokerswhoreceivedtobaccotreatmentintegratedwiththeirpsychiatriccarewerefivetimesmorelikelythansmokerswhoreceivedseparatetreatmenttoreportabstinencefromsmokingninemonthsafterthestudy.ThesmokersreceivingtheintegratedtreatmentweremorelikelytouseNRTandtoreceivemoresmokingcessationsessions.Additionally,cognitivebehavioraltherapytechniquesthatincorporatecognitiverestructuringandexposuretherapytohelppersonslearntotolerateandbecomemorecomfortablewithphysicalsensationsmaybehelpfultopersonswithanxietydisorders(Morissetteetal.,2007).

Substance Use DisordersNotsurprisingly,concurrentuseofalcoholand/orotherdrugsisanegativepredictorofsmokingcessationoutcomesduringsmokingcessationtreatment(Hughes,1996).Long-termquitratesofsmokersinearlyrecoverfromsubstanceusedisorders(SUDs)arelow,atapproximately12percent(Kalman,1998;Sussman,2002).However,personswithapasthistoryofalcoholismdonodiffersignificantlyfromcontrolsubjectsintobaccotreatmentoutcomes(Hayfordetal.,1999).

Thecombinedeffectsofco-occurringsubstanceabuseandsmokingbehaviorsappeartosignificantlyinfluencethehighratesofsmokingcessationtreatmentfailure(Weinbergeretal.,2006).Therearefewstudiesofpharmacotherapeuticinterventionsforsmokinginsubstanceabusers,butsomeevidenceexistssuggestingthatnicotinereplacementandbehavioralapproachesareeffective(Burlingetal.,1996;Shoptawetal.,1996).Areviewoftobaccocessationstudiesbyel-Guebalyetal.(2002)foundthatquitratesrangedfromsevenpercentto60percentaftertreatmentandfrom13percentto27percentat12months.Todate,thereareno

publishedcontrolledstudiesusingbupropionSRinsmokerswithco-occurringSUDs,althoughthesestudiesareinprogress(Weinbergeretal.2006).

Thetimingofsmokingcessationtreatmentforsubstanceabusersremainscontroversial(Weinbergeretal,2006).Somestudiesfoundthatconcurrenttreatmentforsmokingandotherdrugsappearsnottobeassociatedwithincreaseduseofalcoholorotherdrugs(Burlingetal.,2001;Kalmanetal.,2004,2001).Josephetal.(2004)foundthatwhilepatientsinalcoholtreatmentareinterestedinsmokingcessation,participateintreatment,anddemonstratesuccess,theydidnotshowanybenefitfromconcurrenttobaccocessationtreatment.Infact,Josephetal.foundthatdrinkingoutcomeswereworsewithconcurrenttobaccotreatment,suggestingthattobaccocessationinterventionsshouldbeprovidedtopatientsafterintensivealcoholtreatmenthasbeencompleted.

Most relapses occur soon after a person quits smoking, yet some people relapse months or even years after the quit date. Relapse prevention programs can take the form of either minimal (brief) or prescriptive (more intensive) programs.

Components of Minimal Practice Relapse PreventionTheseinterventionsshouldbepartofeveryencounterwithaconsumerwhohasquitrecently.Congratulateeveryex-tobaccouserundergoingrelapsepreventiononanysuccess.Stronglyencouragethemtoremainabstinent.Whenencounteringarecentquitter,useopen-endedquestionsdesignedtoinitiateconsumerproblemsolvingsuchas“Howhasstoppingtobaccousehelpedyou?”Encouragetheconsumer’sactivediscussionofthetopicsbelow:

•Thebenefits,includingpotentialhealthbenefitsthatthe consumermayderivefromcessation.•Anysuccesstheconsumerhashadinquitting(duration ofabstinence,reductioninwithdrawal,etc.).•Theproblemsencounteredorthreatsanticipatedto maintainingabstinence(e.g.,depression,weightgain, alcoholandothertobaccousersinthehousehold).

Components of Prescriptive Relapse PreventionDuringprescriptiverelapseprevention,aconsumermightidentifyaproblemthatthreatenshisorherabstinence.Specificproblemslikelytobereportedbyconsumersandpotentialresponsesfollow:

Lack of support for cessation•Schedulefollow-upvisitsortelephonecallswith theconsumer.•Helptheconsumeridentifysourcesofsupportwithin hisorherenvironment.•Refertheconsumertoanappropriateorganizationthat offerscessationcounselingorsupport.

R E L A P S E P R E V E N T I O N | 2 3

Relapse prevention

R E L A P S E P R E V E N T I O N | 2 4

Negative mood or depressionIfsignificant,providecounseling,prescribeappropriatemedications,orrefertheconsumertoaspecialist.

Strong or prolonged withdrawal symptomsIftheconsumerreportsprolongedcravingorotherwithdrawalsymptoms,considerextendingtheuseofanapprovedpharmacotherapyoradding/combiningmedicationstoreducestrongwithdrawalsymptoms.

Weight gain•Recommendstartingorincreasingphysical activity;discouragestrictdieting.•Reassuretheconsumerthatsomeweightgain afterquittingiscommonandappearstobe self-limiting.•Emphasizetheimportanceofahealthydiet.•Maintaintheconsumeronpharmacotherapy knowntodelayweightgain(e.g.,bupropionSR, nicotine-replacementpharmacotherapies, particularlynicotinegum).•Referconsumertoaspecialistorprogram.

Flagging motivation / feeling deprived•Reassureconsumerthatthesefeelings arecommon.•Recommendrewardingactivities.•Probetoensurethattheconsumerisnot engagedinperiodictobaccouse

Emphasize that beginning to smoke (even a puff) will increase urges and make quitting more difficult.

Notes

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L I T E R A T U R E R E V I E W | 3 3

Literature reviewIndividual Studies

Yr of Pub

2001

1998

2006

1996

2001

2000

Author

Acton,G.,Prochaska,J.,etal.

Addington,J.,el-Guebaly,N.,etal.

Baker,A.,Richmond,R.,Haile,M.,etal.

Borrelli,B.,Niaura,R.,etal.

Brown,R,,Kahler,C.,Niaura,R.,etal

Combs,D.&Advokat,C.

Article Name

Depressionandstagesofchangeforsmokinginpsychiatricoutpatients

Smokingcessationtreatmentforpatientswithschizophrenia

Arandomizedcontrolledtrialofasmokingcessationinterventionamongpeoplewithapsychoticdisorder

DevelopmentofMDDduringsmoking-cessationtreatment

Cognitive-behavioraltreatmentfordepressioninsmokingcessation

Antipsychoticmedicationandsmokingprevalenceinacutelyhospitalizedpatientswithchronicschizophrenia

Setting/ContactType

Outpatientpsychiatricresearchcenter;Survey

Outpatientpsychiatricresearchcenter;Facetoface

Outpatientmentalhealthclinicsorresearchcenter;Facetoface

Facetoface

Facetoface

Inpatient;Facetoface

Volume # /Issue #

AddictiveBehaviors,26(5)

AmericanJofPsychiatry,155(7)

AmericanJofPsychiatry,163(111)

JofClinicalPsychiatry,57(11)

JofConsulting&ClinicalPsych,69

SchizophreniaResearch,46(2-3)

Intervention

Correlationalstudy:205psychiatricoutpatientscompletedmeasuresofdepression(PRIME-MDandBDI-II)

50schizophrenicoutpatientsweredividedinto5groupswhometfor7weeklysmokingcessationprogramsessions

298regularsmokerswithapsychoticdisorderwererandomlyassignedtoatreatmentconditionconsistingof8individualonehoursessionsofmotivationalinterviewingandcognitivebehavioraltherapyorcontrol(treatmentasusual)

144non-depressedSstooktheBDIandtheHamiltonRatingScaleforDepression;txwasfluoxetine

Smokersw/MDDrandomizedtostandardCBTsmokingcessationtxorsmokingcessationtx+CBTtreatmentfordepression

Schizophrenicpatientswhosmokedandwereeitherreceivingatypicalantipsychotic(n=15),clozapine(n=6),oranotheratypicalantipsychotic(n=18)

Results

PatientswhohadneversmokedshowedlowerratesofMDDthanthosewhohadsmoked;patientsinearlystagesofchangedidnotshowmoreMDDordepressivesymptoms,butshowedmorenegativethoughtsaboutabstinence;suggestbuildingsmokingcessationinterventionsbasedonthetranstheoreticalmodelofchangeforusew/psychiatricpops.

42%ofpatientshadstoppedsmokingattheendofthegroupsessions,16%remainedabstinentat3mo,and12%at6mo.;nochangesineitherposornegsymptomsofschizophrenia.

Asignificantlyhigherproportionofsmokerswhocompletedalltreatmentsessionsstoppedsmokingateachofthefollow-uptimesthancontrols(pointprevalenceratesat3months:30%vs6%;6months:18.6%vs4%;12months18.6%vs4%).

5SsmetthresholdcriteriaforMDD.

SmokerwithrecurrentMDDandheavysmokerswhoreceivedCBT-Dweresignificantlymorelikelytobeabstinentthaninstandardtreatment.

Clozapinewasassociatedwithasignificantlylowerincidenceofsmokingthaneithertypicaldrugsorotheratypicalantipsychotics.

L I T E R A T U R E R E V I E W | 3 4

Yr of Pub

1990

2002

1999

2005

2004

Author

Covey,L,Glassman,A,etal.

Covey,L,Glassman,A,etal.

Dalack,G.,Becks,L.,etal.

Evins,A.,Cather,C.,etal.

Evins,A.,Rigotti,C.,etal.

Article Name

Depressionanddepressivesymptomsinsmokingcessation

Arandomizedtrialofsertralineasacessationaidforsmokerswithahistoryofmajordepression

Nicotinewithdrawlandpsychiatricsymptomsincigarettesmokerswithschizophrenia

Adouble-blindplacebo-controlledtrialofbupropionsustained-releaseforsmokingcessationinschizophrenia

Two-yearfollow-upofasmokingcessationtrialinpatientswithschizophrenia:Increasedratesofsmokingcessationandreduction

Setting/ContactType

Facetoface

Facetoface

Outpatientpsychiatricresearchcenter;Facetoface

Recruitedfromcommu-nitymentalhealthcenters;Facetoface

Facetoface

Intervention

Investigationintoresultsofabehaviorallyorientedsmokingcessationprogramshowedsmokersw/MDDhistoryhadlowersuccessrates

134smokerswithhistoryofMDDreceivedSertraline(n=68)ormatchingplacebo(n=66)1wkplacebowashout,9wkdouble-blind,placebo-controlledtreatmentphasefollowedbya9daytaperperiod,anda6mo.drugfreefollow-up;allreceivedintensiveindividualcessationcounselingduring9clinicvisits

19outpatientsw/schizophreniaorschizoaffectivedisorder;1dayofadlibitumsmokingfollowedby3daysofacutesmokingabstinencewhilewearing22mg/dayactiveorplacebotransdermalnicotinepatches,withareturnto3daysofsmokingbetweenpatchconditions

bupropion-SRvsplacebo;andCBT

2yrfollow-uptobupropiontxw/CBT

Results

Firstweek–frequencyandintensityofpsychologicalsymptoms,particularlydepressivemood,werehigheramongsmokerswithpastdepression;interventionsshouldattempttopreventdysphoricsymptomsduringacutewithdrawlperiodforMDDsmokers.

Sertralinetxproducedalowertotalwithdrawlsymptomscoreandlessirritability,anxiety,craving,andrestlessnessthanplacebo;howevernosignificantdifferencebetweenthegroups.

Dyskinesiaswerefoundtohavedecreasedduringabstinenceandplacebopatchtreatment,butincreasedduringabstinenceandtheactivepatchconditions.

Ssinbupropiongrpweremorelikelytobeabstinentfortheweekafterthequitdateandattheendoftheintervention;Ssinthebupropiongrphadahigherrateof4-wkcontinuousabstinence(wks8-12)andalongerdurationofabstinence;relapseishighfollowingthediscontinuation.

MoreSswereabstinentatfollowupthanwereabstinentattheendofthetrial;decreasedsmokingduringthetrialwaspredictiveoflatersmokingreduction.

Volume # /Issue #

ComprehensivePsychiatry,31(4)

AmericanJofPsychiatry,159(10)

Neuropsycho-pharmacology,21(2)

JofClinicalPsycho-pharmacology,25(3)

ClinicalPsychiatry,65(3)

L I T E R A T U R E R E V I E W | 3 5

Yr of Pub

1995

2002

2000

1997

1993

1991

2004

Author

George,T.,Sernyak,M.,etal.

George,T.,Vessicchio,J.,etal.

George,T.,Ziedonis,D.,etal.

Ginsburg,J.,Klesges,R.,etal.

Glassman,A.,Covey,L.,etal.

Greeman,M.&McClellan,T.

Haas,A.,Munoz,R.,etal.

Article Name

Effectsofclozapineonsmokinginchronicschizophrenicoutpatients

Aplacebocontrolledtrialofbupropionforsmokingcessationinschizophrenia

Nicotinetransdermalpatchandatypicalantipsychoticmedicationsforsmokingcessationinschizophrenia

Therelationshipbetweenahistoryofdepressionandadherencetoamulti-componentsmoking-cessationprogram

Smokingcessation,clonidine,andvulnerabilitytonicotineamongdependentsmokers

Negativeeffectsofasmoke-freeruleonaninpatientpsychiatryservice

Influencesofmood,depressionhistory,andtreatmentmodalityonoutcomesinsmokingcessation

Setting/ContactType

Facetoface

Facetoface

Facetoface

Facetoface

Facetoface

Inpatient;Facetoface

Facetoface

Intervention

29schizophrenicoutpatients;clozapinetxvsTYPneuroleptics

bupropion-SRvsplacebo

Ssw/schizoorschizoafftreatedw/NTP&w/eitherATYPorTYPantipsychotics;GToftheAmerLungAssnorGTforsmokersw/schizothatemphasizedmotivationenhancement,relapseprevention,socialskillstraining,andpsychoeducation

13wkCBG&randomassignmenttonicotinegum,appetitesuppressantgum,orplacebogum

Clonidine

SmokingbanoninpatientunitsataVeteransAffairsmedicalcenter

549Ss(28%w/historyofMDD);CBTvs.HE

Results

Therewasasigdecreaseinreporteddailyciguseafterclozapinetx.

Bupropion-SRincreasedsmokingabstinencerates;possymp–notaffected,negsympreduced;ATYPuseenhancesmokingcessationresponsestoBUP.

EffectsofNTParemodestinschizophrenicpatients;nodifferenceinGTprograms;ATYPmaybesuperiortoTYPincombinationw/NTPforsmokingcessationinschizophrenicpatients.

GroupCBTisaneffectivesmoking-cessationprogramforwomenwithahistoryofdepressionwhoarenotcurrentlydepressed.

MDDpredicttxfailure;anincreasedriskforpsychiatriccomplicationsaftersmokingcessationwasapparentamongsmokerwithMDD,particularlybipolar.

20-25%ofpatientswhosmokedhaddifficultyadjustingtotherule,andsomepatientsexperiencedmajordisruptionintheirtx.

MDD-RSshadhigherratesofabstinenceinCBTcomparedw/HE,evenwhenthecontributionofmoodandtheinteractionbetweenmoodandanMDDxtxvariablewereincludedinthemodel.

Volume # /Issue #

JofClinicalPsychiatry,56(8)

BiologicalPsychiatry,52(1)

AmericanJofPsychiatry,157(11)

AddictiveBehaviors,22(6)

ClinicalPharmacology&Therapeutics,54(6)

Hospital&Community,42(4)

JConsultClinPsychol,72(4)

L I T E R A T U R E R E V I E W | 3 6

Yr of Pub

1994

1998

1996

2005

Author

Hall,S.M.,Reus,V.I.,MunozR.F.,etal

Hall,S.M.,Reus,V.I.,MunozR.F.,etal

Hall,S.M.,Reus,V.I.,MunozR.F.,etal

Haug,N.A,Hall,S.M.Prochaska,J.J.etal.

Article Name

Cognitive-behavioralinterventionincreasesabstinenceratesfordepressive-historysmokers

NortriptylineandCBTinthetreatmentofcigarettesmoking

Moodmanagementandnicotineguminsmokingtreatment:Atherapeuticcontactandplacebo-controlledstudy

Acceptanceofnicotinedependencetreatmentamongcurrentlydepressedsmokers

Setting/ContactType

Facetoface

Facetoface

Facetoface

Outpatientpsychiatricresearchcenter;Self-reportandstructuredinterviewmeasures

Intervention

149smokers(31%hadahistoryofMDD);allreceived2mg/dayofnicotinegum;MMprovidedin10groupsessionsover8wks;standardtxprovidedin5gpsessionsover8wks

HxofMDDvs.NohxofMDDrandomizedtoNortriptylinevs.placeboandCBTvs.control

Moodmanagement(MM)vs.contact-equivalenthealtheducation(HE);and2mgto0mgofnicotinegumforsmokersw/historyofMDD

Thisstudyreportsonbaselinecharacteristicsassociatedwithacceptanceandrefusalofavailablesmokingtreatmentamongcurrentlydepressedsmokersinapsychiatricoutpatientclinic.Thesample(N=5154)was68%femaleand72%White,withameanageof41.4yearsandaveragesmokingrateof17cigarettes/day.Allparticipantswereassignedtoarepeatedcontactexperimentalcondition;receivedastage-basedexpertsystemprogramtofacilitatetreatmentacceptance;andwerethenofferedsmokingtreatment,consistingofbehavioralcounseling,nicotinepatch,andbupropion

Results

Ssw/MDDweremorelikelytobeabstinentwhentreatedw/MM,andlessangeratbaselinewaspredictiveofabstinence.

Nortriptyline-higherabstinenceratesthanplacebo,independentofdepressionhx.CBT-Moreeffectivefor+hxMDD.Smokerswithhxofdepressionareaidedbymoreintensivepsychosocialtreatments.

MMandHEproducedsimilarabstinencerates:2mggumwasnomoreeffectivethanplacebo;MDDpatientshadagreaterincreaseinmooddisturbanceafterthequitattempt;MDDpatientsmaybebesttreatedbyinterventionsprovidingadditionalsupportandcontact,independentoftheraputiccontact.

Thenumberofdaystotreatmentacceptancewassignificantlypredictedbystageofchange,withthoseinpreparationenteringtreatmentmorequicklythancontemplatorsorprecontemplators.Inalogisticregression,thevariablesmoststronglyassociatedwithacceptingtreatmentwerecurrentuseofpsychiatricmedicationandperceivedsuccessforquitting.Severityofdepressivesymptoms,durationofdepressionhistory,andhistoryofrecurrentdepressionwerenotrelatedtotreatmentacceptance.Findingshaveimplicationsforthepsychiatricassessmentandtreatmentofsmokersinclinicalsettings.Psychiatricmedicationmayplayasignificantroleinsmokingcessationtreatmentacceptancebycurrentlydepressedsmokers.

Volume # /Issue #

JConsultClinPsychol,62(1)

ArchivesGenPsych,55

JofConsulting&ClinicalPsych,64(5)

Nicotine&TobaccoResearch,7(2),(April2005)217–224

L I T E R A T U R E R E V I E W | 3 7

Yr of Pub

1999

2000

2000

1997

2002

1998

Author

Hayford,K.,Patten,C.,etal.

Keuthen,N.,Niaura,R.,etal.

Lucksted,A.,Dixon,L.,etal.

Martin,J.E.,Calfas,K.J.,PattenCA,etal.

Niaura,R.,Spring,B.,Borelli,B.,etal.

Patten,C.A.,Martin,J.E.,Meyers,M.G.,etal.

Article Name

Efficacyofbupropionforsmokingcessationinsmokerswithaformerhistoryofmajordepressionoralcoholism

Comorbidity,smokingbehaviorandtreatmentoutcome

Afocusgrouppilotstudyoftobaccosmokingamongpsychosocialrehabilitationclients

Prospectiveevaluationofthreesmokinginterventionsin205recoveringalcoholics:One-yearresultsofProjectSCRAP-Tobacco

Multicentertrialoffluoxetineasanadjuncttobehavioralsmokingcessationtreatment

Effectivenessofcognitive-behavioraltherapyforsmokerswithhistoriesofalcoholdependenceanddepression

Setting/ContactType

Facetoface

Facetoface

Facetoface

Facetoface

Facetoface

Facetoface

Intervention

615smokersreceivedplaceboorbupropion-SRat100,150,or300mg/dayfor6wksaftertargetquitdate

120smokers;10wksmokingcessationtrialw/fluoxetine&behavioraltx;62.3%ofSswerediagnosedwithalifetimemood,anxietyorSUD

5focusgroups(6-10Sseach)40clientsinpsychosocialrehabilitationprograms.Discussedprosandconsofsmokingandnotsmoking.

Randomized:standardtreatment(ALAquitprogram+nicoticeanonymousmeetings)(ST),behavioralcounseling+exercise(BEX),orbehavioralcounselingplusnicotinegum(BNIC)

Randomizedto3doseconditions:10weeksofplacebo,30mg,or60mgfluoxetineplus9weeksCBT

Randomized:behavioralcounseling(BC)orBC+CBT

Results

Doseresponseeffectoftxforsmokingcessationwasfound.

Lifetimecomorbiditywasrelatedtohighersmokingratesandnicotinedependence,depressedmoodandgreaterselfreportofanxietyandstress.BaselinescoresontheBDIwererelatedtotxoutcomeforSsw/opositivehistoryofanypsychiatricdisorder,withlowerBDIscoresmorefreqinthosewhowereabstinent.

Resultsindicatethatissuesandneedsthatarespecifictosmokerswhousementalhealthservicesmustbeaddressedinthedevelopmentofsmokingpreventionandcessationinterventionsinpsychosocialrehabilitationandothermentalhealthprograms.

BEX=significantlyhigherquitratesatpost-treatment,notat6or12months.

Analysesassumingmissingdata=smokingobservednotreatmentdifferenceinoutcomes.Pattern-mixtureanalysisthatestimatestreatmenteffectsinthepresenceofmissingdata=enhancedquitratesassociatedwithboththe60-mgand30-mgdoses.

SignificantlymoresmokersinCBTquitatpost-treatmentand12monthfollowup.

Volume # /Issue #

BritishJofPsychiatry,174

Psychotherapy&Psycho-somatics,69(5)

PsychiatricServices,51(12)

JofConsulting&ClinicalPsych,65(1)

JofConsulting&ClinicalPsych,70(4)

JofStudiesonAlcohol,50(3)

L I T E R A T U R E R E V I E W | 3 8

Yr of Pub

2000

1997

2006

2001

1997

Author

Patten,C.A.,Martin,J.E.,Calfas,K.J.,etal.

Rabois,D.,Haaga,D.

Thorndike,F.P.,Friedman-Wheeler,D.G.,Haaga,D.A.

Weiner,E.,Ball,M.P.,Summerfelt,A.,etal

Ziedonis,D.M.,George,T.P.

Article Name

Briefreporteffectofthreesmokingcessationtreatmentsonnicotinewithdrawalin141abstinentalcoholicsmokers

Cognitivecoping,historyofdepression,andcigarettesmoking

Effectofcognitivebehaviortherapyonsmokers’compensatorycopingskills

Effectsofsustained-releasebupropionandsupportivegrouptherapyoncigaretteconsumptioninpatientswithschizophrenia

Schizophreniaandnicotineuse:Reportofapilotsmokingcessationprogramandreviewofneurobiologicalandclinicalissues

Setting/ContactType

Facetoface

Interview

Facetoface

Outpatientpsychiatricresearchcenter;Facetoface

Facetoface

Intervention

Randomizedto12weekprogramofStandardTreatment,behavioralcounselingplusexercise,orbehavioralcounselingplusnicotinegum

TestedpremisethatformerlydepressedsmokersarelackingincognitivecopingskillstaughtinCBT.4groups(depressed/not,smoker/not)completedWORtotestcognitivecoping

RandomizedtoCBTorcomparisonconditionofeducationandscheduledsmokingreduction.(uniquetoCBTconditionwascognitiverestructuringformoodmanagement)

9sessionsofweeklygrouptherapyinconjuctionwithopenlabelbupropiontreatment(150mg/twiceaday)for14weeks

24schizophrenicpatients:Nicotinereplacement,motivationalenhancementtherapy,andrelapsepreventionbehavioraltherapy

Results

Nosignificanteffectoftreatmentonpercentagereductioninsmokingrate.All3groupsshowedsimilaroverallreductionsinsmokingrate.

HxofdepressionassociatedwithsignficantlymorenegativeresponsesonWOR.“Thisstudysuggeststhatpeoplewithahistoryofdepressiontendtolacksuchskillsandmightthereforeespeciallybenefitfromincorporationofcognitivebehaviortherapyprinciplesinsmoking-cessationprograms.”

CBTgroupdidNOTshowmoreimprovementincompensatorycopingskills(measuredbyWaysofResponding).AnonsignificanttrendfavoringCBTwasfoundinpost-treatmentabstinence.

Noneofthesubjectsquitsmoking.However,measuredchangeinexpiredbreathcarbonmonoxidelevelsindicatedreductioninsmoking.

50%completedtheprogram,40%decreaseduseby50%,and13%remainedabstinentfor6months.

Volume # /Issue #

AddictiveBehaviors25(2)

AddictiveBehaviors,22(6)

AddictBehav,Jan18

AmJofPsychiatry,158

SchizophreniaBulletin,23(2)

L I T E R A T U R E R E V I E W | 3 9

Review Articles

Yr of Pub

1992

1998

1999

2002

1995

2003

1993

2001

1998

Author

Dalack,G.W.&Glassman,A.H.

Dalack,G.W.,Healy,D.J.,etal.

Dursun,S.M.&Kutcher,S.

el-Guebaly,N.&Cathcart,J.

Hughes,J.R.&Frances,R.J.

Martinez-Raga,J.&Keaney,F.

Resnick,M.P.

Ziedonis,D.,Krejci,J.,etal.

Ziedonis,D.M.,Wyatt,S.A.,etal.

Article Name

Aclinicalapproachtohelppsychiatricpatientswithsmokingcessation

Nicotinedependenceinschizophrenia:Clinicalphenomenaandlaboratoryfindings

Smoking,nicotineandpsychiatricdisorders:evidencefortherapeuticrole,controversiesandimplicationsforfutureresearch

Smokingcessationapproachesforpersonswithmentalillnessoraddictivedisorders

Howtohelppsychiatricpatientsstopsmoking

TreatmentofnicotinedependencewithbupropionSR:Reviewofitsefficacy,safetyandpharacologicalprofile

Treatingnicotineaddictioninpatientswithpsychiatricco-morbidity

Integratedtreatmentofalcohol,tobacco,andotherdrugaddictions

Currentissuesinnicotinedependenceandtreatment

Volume # /Issue #

PsychiatricQuarterly,63(1)

AmericanJofPsychiatry,155(11)

MedicalHypotheses,52(2)

PsychiatricServices,53(9)

Psychiatric`Services,46(5)

AddictBiol,8(1)

Nicotineaddition:Principlesandmanagement,pp.327o-336(eds:Orleans,C.T.&Slade,J.D.)

Integratedtreatmentofpsychiatricdisorders(ed:Kay,J.)Reviewofpsychiatry,20(2)

Newtreatmentsforchemicaladdictions(eds:McCance-Katz,E.F.&Kosten,T.R.)Reviewofpsychiatryseries.

Conclusions/Discussion

Adiscussionoftheinterfaceofpsychiatricillnessandsmoking,particularlyamongthosechronicallyhospitalizedinpsychiatricinstitutions.Itsuggestsarationalapproachtohelppsychpatientsstopsmoking.

Clinicaldatasuggestthatsmokinginschizophreniaisanattempttoself-medicate(negative)symptoms.Knowledgeontheeffectsofnicotineonschizopatientsmayleadtonewtreatmentforbothdxandtx.

Investigatedthreecomponentsofthesocial-scientific-ethicaldilemmathatresearcherslookingintothepossibletherapeuticeffectsandthemechanismsofactionofnicotineinneuropsychiatricdisorders.

Reviewof24empiricalstudiesofoutcomesofsmokingcessationapproachesusedwithsamplesofpersonswithmentaldisorders.Foundthatthemajorityofinterventionscombinedmedicationandpsychoeducation.

ThisarticlefoundthatbupropionSRappearstobeasafe,well-toleratedandeffectivemedicationincombinationwithsmokingcessationcounsellingforawiderangeofsmokers.

Exploretheuniquecircumstancesofpsychiatricpatients,therelationshipbetweenpsychiatricdisorderandnicotineaddition,andspecialproblemsinpsychiatricinstitutions/recentresearchontheinteractionbetweensmokingcessation,relapse,andmooddisorderisreviewed/discussesinteractionbetweenpsychotropicmedicationsandsmoking.

Empiricalliteratureontheeffectivenessofcombinedtreatmentofspecificsubstanceusedisorders.Reviewof3oftheleadingpsychotherapiescurrentlyinuseinthetreatmentofpatientswithsubstanceabusedisorders:12-step,motivationalenhancementtherapy,andrelapseprevention.

Pharmacotherapiescanbeintegratedwithbehavioralmanagementtechniquesthatareindividualizedtotheneedsofthepatient.

"This course was developed from the public domain document: Smoking Cessation for

Persons with Mental Illnesses: A Toolkit for Mental Health Professionals – University of

Colorado Anschutz Medical Campus: Behavioral Health & Wellness Program.”