SMEs Buffers andRiskstechnology copiers

unfaithful staffcontrols

competitors

Economic downturn,Political issues, security threats,

Industrial espionage,

International issues

Media, NGOs, Community orgs

Public trendsCompetitors,

Business networks

Tax regime, Legal

Liabilities,government regulations,Insurance auditors

SMEs Social Capital

Risk assessment, Licensing, Patenting, Trade Mark,IP technology transfer, distribution

Networks, venture capitals, angels, banks, Customers, public, media,NGOs, government regulation

Scientists, research staff, university, technology

transfer

SMEs are funded by entrepreneurs, venture capitals, angels, govt orgs, mergers, univer. Com Dev, Healthcare & Life Sci, Energy, Envir, Aerospace, Defence, Auto,

Agriculture, Sports, Construction, Textiles, etc... Corporations fund subsidiary nanotechnology cos. www.fundmap.co.uk/ektn/

• Number of Small Manufacturers:

Nanomaterials, nano components and sensors: 81 Companies

• Develop services (univ. & gov agency): 40 companies

• Tools, Equipment Analytical Inst.: 125• Business services, financial, traders,

venture capitals/Angel: 85 Companies• Technical services: 80 Companies • (source: Survey Small Times 2008)

• Number of employees: NicoForm 9, BioForce 15 (increase of 572% revenue/year), microfluidic ChipShop GmbH 15, Micronit Microfluidics BV 25, Nano and Micro Technology Consultants (R&D consulting) US 5, Optical Associates Inc (OAI) US, Optotrack Inc US 4, Parallel Synthesis Technologies (Stanford Univ. including Anticounterfeiting Technology for Pharmaceutical Products), Steele Tech 5, (microfluidic, microreactors), US Photonics Inc 5 employees

• Johnson Mattey, Agilent, Aerotech, ASML, Cranfield, Cranfield, ASPE, IBS, Moore Tools, Oxford Instruments, OXONICA, Run3D, Precitech,

• Resonetics Inc (medical & laser) 125 • Steinmeyer FMD 110 • Kionix Inc, 100 employees

66400 Nanotechnologists, 643 NanoTechnology Cos (listed in KTN 2005), 1000 technology involved,

ISIS (Technology Transfer) 50 start-ups revenues £4.7 m/07, distributed 2.5 m to Oxford Univ researchers

• For UK private equity, and info hubs: Euspen, IoN, LTN, MNT= where they can be introduced, advertise and find potential investors, buyers, development partners, Pharmaceuticals, Drug Delivery, Medical Supplies and Devices, Implants, Coatings, Wound Care, Diagnostics, Imaging and Tissue Engineering.

• Financial highlights of Biomedica (LSE OXB): Revenue 13 m, R&D cost 13.4 m, Net loss 1.1 m (2006)

• Oxonica plc, OXONICA AIM in 2006 (OXN.L) : The company has four operating divisions: Oxonica Energy, Oxonica Diagnostics, Oxonica Materials and Oxonica Security. Revenues:

• 2008 2007 2006 2005 2004 2003 2002• 1200 3124 9160 1,247 391 210 118,5

• OXAGEN: Up until 2005 the Company had raised some £48m in private equity. In May 2005 the company closed a further series B private equity funding led by MPM Capital of $60 m, one of the largest financings in Europe.

total global market for nanotechnology £ 3 trillion by 2015

(Department of Trade and Industry, 2002)

• NANO MATERIALS: 30%

• NANO INFORMATION TECHNOLOGY:30%

• NANO HEALTHCARE: 15%

• NANO TOOLS: 10%

• NANO ENERGY, OTHERS: 15%

(Guide to the Credit Suisse Global Nanotechnology Index, February 2008)

• Europe as a whole lags substantially behind both the US and Japan (Greenpeace, 2003), companies in Eu have legal liability to REACH!

• US National Institute of Stands and Tech (NIST) is co-developing WIKI-NANO a collaborative website on standard methods for minimizing the environmental, health and safety risks of nanotechnology.

• The “21st Century Research and Development Act” has resulted in an investment of over a billion dollars annually over the past five years in nanotech research

• http://www.nanobusiness.org • Market forcast for nano products to

reach trillions of dollars within the next 10 to 15 years, according to industry experts. (Credit Suisse Analyst, 2008).

Private Equity, the PRIORITY: VISIBILITY

• ….. the more we explain what we do, the more people will come to understand that private equity is a “force for good”

• …Private equity … should themselves produce an annual review -  again freely available on their web-sites - setting out their values and providing information about governance, management, performance and so on.

• We need to provide a lot more information about the overall performance of the private equity industry by carrying out more research.

• Source: Simon Walker, BVCA,The British Private Equity and Venture Capital Association, Nov 2008

SMEs Microsystems & Nanotechnologies Integrators & Developers (source: Small Times 2008)

Market Analysis Reports (price approx. £1000)

• Biomedical sciences 51, Chemicals 25, • Consumer products 12, Energy envir 12, • Photonics 24, Safety/security/defense 17,

Transportation/Auto/Aero 13

• Thomond et al (2003): “disruptive innovations first establish their commercial footing in new or simple market niches by enabling customers to do things that only specialists could do before … these new offerings, through a period of exploitation, migrate up-market and eventually redefine the paradigms and value propositions on which the existing industry is based.”

Sigma Aldrich SIAL, life Sci.&High Tech, 35 countries, 6800 employees,

Philips Most Ethical, 38th most innovative,

• Sigma Aldrich SIAL, Life Science & High Technology, 35 countries, 6800 employees, Aldrich(R) Releases Materials Science Catalogue That Included Products to Advance Sustainable Energy and Nanotechnology Nanopowders 151,nanoparticles 32, naoparticles Oxides 106, surface functionalized NP 8, Quantum Dots 9, carbon NM 49, Nanominerals: nanoclays 7, Dendrimers 194, Mesoporous Materials 12, nanohybrids 137

• Stock prices steady rise since 2003

• "materials by application" Materials Science catalogue 4000 products

• http://www.sigma-aldrich.com/mscat

• Philips Health and Well-being, 4.16 billion net Income 2007

• Philips Ultra sound microbubble, Microbubbles are typically less than 5 microns (millionths of a meter) in diameter, which makes them no bigger than red blood cells. As a result, they can pass through even the smallest of blood vessels.