Data File #F807-DST-009-Rev1

SmartGlassBioreactor

SmartParts | Bioreactor Vessels

SmartGlass for Cell Culture and Fermentation

Boost cell densities and product yieldDesigned for R&D and process development scale-up, SmartGlass

vessels provide easy operation and rapid assembly. Developed

to ensure complete process sterility and minimize lost batches,

the vessels are manufactured with the highest standards for

materials and surface finish. Improved efficiency of aeration,

feeding, and monitoring improve cell growth and expression.

Reduce down time with easily handled components and fittingsThe Finesse SmartGlass vessel has been optimized to minimize

downtime for cleaning and set-up. The motor adapter utilizes

coupling adapter windows and an alignment marker for easy

assembly. Innovative sensor holders allow probes to be inserted

quickly without compromising the sterile environment.

Best power transfer and thermal performanceDeveloped using a computational fluid dynamics (CFD) simulator,

our impellers were created to provide maximum mixing with

minimum shear force, resulting in a higher average kLa. The

cold finger has been replaced by a cooling loop to increase the

thermal surface. Our current performance tests demonstrate

a cooling rate two times better than the competition.

Heating BlanketThe heating blanket has been designed for rapid thermal

transfer. A bi-metallic termperature limiting switch embedded

in the blanket ensures safety against overheating or fires.

SmartGlass Accessory KitsFinesse provides specialized accessory kits for

SmartGlass that enable the user to configure

the vessel according to the intended use.

The Fermentation Kit

This kit includes a six-blade Rushton

impeller, a Frit macrosparger assembly,

a condenser, and baffles.

The Cell Culture Kit

This kit includes two impellers (Rushton

6-blade and marine 3-blade), an L-pipe

microsparger assembly, and closures for

unused openings in the head plate.

The Common Accessories Kit

This kit includes an open-pipe sparger, a sample

pipe, septum and triple-inlet assemblies.

Finesse SmartMotor

SmartParts | Bioreactor Vessels

1 Stirrer Assembly (M18x1.5)

2 Sensor Holder pH (M24x1.5)

3 Septum Holder (M18x1.5)

4 Air Outlet Condenser* (M24x1.5)

5 Cold Loop (10mm 2x)

6 Medium Triple Inlet (M18x1.5)

7 Sensor Holder (M24x1.5)

8 Porous L-Pipe or Ring Sparger (10mm)

9 Air Overlay

10 Adjustable Harvest Pipe

11 Open Pipe Sparger (10mm)

12 Adjustable Foam Level (10mm)

13 Thermometer Pocket (10mm)

14 Baffles* (6mm)

*Fermentation use

SmartGlass Top Plate Layout

1

23

4

5

6

7

89

9

10

11

12 131414

14

SmartGlassSPECIFICATIONS

VESSEL SIZE 1L 3L 7L

Length 205 mm (8.1 in) 260.5 mm (10.25 in) 385 mm (15.2 in)

Width 110 mm (4.33 in) 140 mm (5.5 in) 170 mm (6.7 in)

Inner Diameter 100 mm (3.9 in) 130 mm (5.1 in) 160 mm (6.3 in)

VOLUME (L)

Total 1.52 3.28 7.43

Working 1 2 5

Minimum Working 0.5 1.2 2.5

Wetted material Borosilicate Glass, SS316L, Silicone

Every effort has been made to ensure the accuracy of the information in this document. However, Finesse

reserves the right to change its products without notice. The following are Finesse Solutions, Inc. registered

trademarks: TruView, TruBio, TruBio DV, TruBio µC, SmartOPC, TruService, TruTorr, TruFluor, TruLogic, TruConnect,

TruMigrations, TruCables, TruHousings, SmartGlass, SmartRocker, TruDO, TrupH, SmartFactory, SmartChip,

SmartSystems, SmartBag, SmartPuck, SmartReader, SmartBag Reader, SmartTray, SmartController, SmartSensor.

© 2013-2014, Finesse Solutions, Inc. All other trademarks are the property of their respective owners.

Finesse Solutions, Inc.

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