SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older...
21
SLEEP DISORDERS A Pathophysiological Model by Allan Hobson Harvard Medical School
Transcript of SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older...
![Page 1: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/1.jpg)
SLEEP DISORDERS
A Pathophysiological Model
byAllan Hobson
Harvard Medical School
![Page 2: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/2.jpg)
![Page 3: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/3.jpg)
![Page 4: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/4.jpg)
![Page 5: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/5.jpg)
![Page 6: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/6.jpg)
![Page 7: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/7.jpg)
![Page 8: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/8.jpg)
![Page 9: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/9.jpg)
![Page 10: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/10.jpg)
![Page 11: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/11.jpg)
![Page 12: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/12.jpg)
![Page 13: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/13.jpg)
![Page 14: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/14.jpg)
![Page 15: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/15.jpg)
Normal Sleep is a Product of
Dynamic Neuronal Interaction
![Page 16: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/16.jpg)
Changes in the Balance of Neuronal Interaction Causes Abnormal Sleep
![Page 17: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/17.jpg)
BRAIN STEMas a set of Coupled OscillatorsCircadian-HypothalamusUltradian-PonsRespiratory-Medulla
![Page 18: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/18.jpg)
MEDIATING FACTORSSet point Changes Timing Errors
![Page 19: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/19.jpg)
NARCOLEPSYGelineau’s Tetrad
Sleep AttacksCataplexyHypnogogic HallucinationHypnopompic Hallucination
![Page 20: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/20.jpg)
SLEEP APNEA SYNDROMESCentral Factors
Peripheral FactorsInteraction
![Page 21: SLEEP DISORDERS A Pathophysiological Model by Allan Hobson … · REM SLEEP BEHAVIOR DISORDER Older Men Act Out Dreams Loss of Muscle Inhibition Harbinger of Parkinson’s Disease.](https://reader033.fdocuments.in/reader033/viewer/2022042022/5e79fb1c84b13001992d53c1/html5/thumbnails/21.jpg)
REM SLEEP BEHAVIOR DISORDER
Older MenAct Out DreamsLoss of Muscle InhibitionHarbinger of Parkinson’s Disease