Consumer Care

Personal Care

Vivillume™Skin Tone that Appears Lit from Within

INCI Name: Water & Strelitzia nicolai Seed Aril Extract Preservative System: Phenoxyethanol SAP Code#: 140350

Key Product Attributes

– Restores skin luminosity – Promotes even skin tone – Fights under-eye dark circles – Decreases under-eye puffiness – Recaptures skin’s youthful vitality

Use Level

1 – 3%

In situ Studies

Bilirubin Degradation0.01% bilirubin samples were run on HPLC, sampling every 2 hours for 24 hours to determine the degradation of the bilirubin. MAP and Vivillume™ were added to some of the bilirubin solution samples.

Results

2% Vivillume™ was able to cause rapid degradation of the bilirubin solution in situ.

Personal Care – Vivillume™

100%

90%

80%

70%

60%

50%

40%

30%

20%

10%

0%

Time (hr)

perc

ent o

f bili

rubi

n re

mai

ning

0 10 20 30 40

In situ Effect of VivillumeTM on Bilirubin Degradation as Measured by Percent Bilirubin Remaining vs. Time

1.0% MAP control + Bilirubin solution2% Vivillume™ + Bilirubin solution

2% Vivillume™ & 1% MAP + Bilirubin solution

Fig. 1

The Vivillume™ aril extract was able to cause rapid degradation of the bilirubin solution in situ. The MAP control shows that MAP was able to prevent bilirubin degradation, implying that the bilirubin control was degrading through an oxidative step. When Vivillume™ and MAP were combined with bilirubin, the bilirubin solution still degraded at a rate similiar to without MAP, implying that Vivillume™ degrades bilirubin through an oxidative-independent mechanism.

0.01% Bilirubin control

60,000

50,000

40,000

30,000

20,000

10,000

0.00%

Type

III C

olla

gen

(ng/

ml)

In Vitro increase of Type III Collagen

Untreated 100 µg/ml Sodium

Ascorbate

2% Vivillume™ 1% Vivillume™ 0.5% Vivillume™

Fig. 2

Expression of Collagen Type III is markedly increased in the cells treated with Vivillume™. This could translate into skin that is more luminous.

Treatment

**

Vivillume™

In Vivo StudiesIn Vivo Study Protocol

Full face study – 60 day treatment – 50 subjects – 2 Groups – Test Products

– Placebo – 2% Vivillume™

Three key skin aging parameters were evaluated via visual grading of clinical photographs

Results

Panelists using 2% Vivillume™ experienced a statistically significant improvement in skin tone and radiance, a decrease in appearance of under eye circles and a decrease in appearance of under eye puffiness

18.00%

16.00%

14.00%

12.00%

10.00%

8.00%

6.00%

4.00%

2.00%

0.00%

perc

ent i

mpr

ovem

ent

Placebo 2% Vivillume ™

In vivo Improvement of Three Skin Targets Measured by Professional Evaluation of Clinical Photographs

Improvement in skin tone and radiance

Decrease in under-eye circles

Decrease in under-eye puffiness

Fig. 3

Panelists using 2% Vivillume™ experienced a statisically significant improvement in skin tone and radiance, a decrease in appearance of under-eye circles and a decrease in appearance of under-eye puffiness.

Personal Care – Vivillume™ – 9/14

www.lonza.com www.lonza.com/personalcare

This product information corresponds to our knowledge on the subject at the date of publication and we assume no obligation to update it. It is offered without warranty, and is intended for use by persons who are experienced and knowledgeable in the field and capable of determining the suitability of ingredients for their specific applications. Because we cannot anticipate all variations in actual end-use conditions, we assume no liability and make no warranty in connection with your use of our products or product information. We do not guarantee the efficacy of active ingredients, delivery systems, functional ingredients, rheology modifiers, na-tural or botanical products, preservative and protection systems or proteins in any specific application or use. The information we provide is not intended to substitute for testing. You should per-form your own tests to determine for yourself the suitability and efficacy of ingredients in your application and conditions of use. The information we provide should not be construed as a license to operate under or a recommendation to infringe any patent or other intellectual property right, and you should ensure that your use does not infringe any such rights. Our products are for industrial use only. WE MAKE NO WARRANTY (INCLUDING AS TO MERCHANTABI-LITY OR FITNESS FOR PURPOSE) OF ANY KIND, EXPRESS OR IMPLIED, OTHER THAN THAT OUR PRODUCTS CONFORM TO THE APPLICABLE PRODUCT SPECIFICATIONS.

© 2014 Lonza Ltd

USALonza Consumer Care70 Tyler PlaceSouth Plainfield, NJ 07080Tel +1 908 561 5200

SwitzerlandLonza LtdMuenchensteinerstrasse 384002 BaselTel +41 61 316 81 11

Day 0 Day 60Fig. 4

Under visible light, there is an improvement in the panelist’s under-eye dark circles, an increase in skin luminosity and a decrease in unevenness of the skin.

Trade Name INCI Preservative

Vivillume™ Water & Strelitzia Nicolai Seed Aril Extract

Phenoxyethanol

Vivillume™ ECT Water & Strelitzia Nicolai Seed Aril Extract

Geogard ECT

Vivillume™ CR Water & Hedychium coronarium

Phenoxyethanol