Simonetta ScalviniFondazione Salvatore Maugeri, Telemedicine Service, Lumezzane (BS),

Italy

Clinical ResultsClinical Results

Bruxelles, 16tn June 2011

16th June 20112

Baseline characteristics of patients

TELEMACO(2007-2010)

NRS(2006 – 2009)

No of patientsAge, years (mean ± SD)

13069 ± 13

80271 ± 11

Female (%) 33 (25%) 226 (28%)

Onset of symptoms < 6 months (% patients)

Onset of symptoms > 6 months (% patients)

81 (62%)48 (37%)

292 (36%)507 (63%)

NYHA Class IINYHA Class III-IV

17 (13%)113 (82%)

0 (0%)802 (100%)

Patients with 0 – 1 co-morbidity (% patients)

Patients with ≥ 2 co-morbidities104 (80%)26 (20%)

408 (63%)294 (37%)

Patients with ≥ 2 admissions in 6 months before (% patients)

40 (31%) 208 (26%)

Home Base TelemanagmentHome Base Telemanagmentin Chronic Heart failure (CHF)in Chronic Heart failure (CHF)

Home Base TelemanagmentHome Base Telemanagmentin CHF: clinical resultsin CHF: clinical results

3

Telephone calls and Telephone calls and actions takenactions taken

TELEMACO(2007-2010)

NRS(2006 – 2009)

for week for HBT period for week for HBTperiod

No of scheduled calls/patient 1.198 30.9 1.393 23.1

No of unscheduled calls/patient

0.084 1.7 0.094 1.4

No of ECG transmissions/patient

1.083 28.2 1.363 22.3

No of changes in therapy/patient

0.199 4.6 0.211 3.7

No of ED suggested 0.014 0.2 0.030 0.3Clinical eventsClinical events TELEMACO

(2007-2010)NRS

(2006 – 2009)

Cardiovascular (including HF) readmission 0.27 ± 0.62 0.34 ±0.63

Non Cardiovascular readmission 0.15 ± 0.45 0.15 ± 0.44

16th June 2011

OutcomeOutcome T0 T1 p

Ejection Fraction (%)

31.8 ± 11 40.2 ± 11.3 0.000

Walking Test 351 ± 127 363 ± 166 0.052

Minnesota QoL 42.5 ± 20.0 23.5 ± 18.6 0.000

16th June 20114

Baseline characteristics of patients

TELEMACO(2007-2010)

No of patientsAge, years (mean ± SD)

39372 ± 8

Female (%) 84 (21%)

Diagnosis 58 % in clinical stable conditions

Therapy46 % in oxygen-therapy for 24H

27 % in oxygen-therapy only over night or under-stress

Functional exams 55 % with FEV1 < 50%

Smoke history - Smokers - No smokers-- Ex smokers

62 (37%)39 (16%)282 (10%)

BMI:- Under weight- Normal weight- Over weight- Obese

15 (4%)121 (31%)142 (36%)104 (26%)

Home Base TelemanagmentHome Base Telemanagmentin Chronic Obstructive Pulmonary Disease (COPD)in Chronic Obstructive Pulmonary Disease (COPD)

severe or very severe COPD (III - IV GOLD class )

516th June 2011

Home Base TelemanagmentHome Base Telemanagmentin COPD: resultsin COPD: results

Telephone calls and Telephone calls and actions takenactions taken

TELEMACO(2007-2010)

for week for HBT period

No of scheduled calls/patient 1.07 ± 0.74

25.6 ± 7.6

No of unscheduled calls/patient

0.05 ±0.26 0.7 ±1.2

No of SpO2 transmissions/patient

1.0 ± 0.77 23.6 ± 8.2

No of changes in therapy/patient

0.110 2.58

No of ED suggested 0.017 0.074Clinical eventsClinical events TELEMACO

(2007-2010)

Pulmonary readmission (per patient for HBT period)

70 (0.18)

Non Pulmonary readmission (per patient for HBT period)

47 (0.12)

OutcomeOutcome Coupled value

T1-T0 p

San George Questionnaire:- Symptoms- Activity- Impact

323323322323

-2.384-2.736-4.016-2.984

0.0170.0060.0000.003

Second opinion for GPs: ResultsSecond opinion for GPs: Results

Total No of Total No of teleconsultationteleconsultation

TELEMACO(2007-2010)

At patient’s home 489 (10%)

Patients’ follow up 2828 (58%)

Patients’ new symptoms 1890 (39%)

Patient’s age (y)Sex (male)

62 ± 201935 (45%)

7

Second opinion for GPs: resultsSecond opinion for GPs: results

After the second opinion, GPs change their decisions in After the second opinion, GPs change their decisions in the 87% of the patientsthe 87% of the patients

Second opinion on cranium TC Second opinion on cranium TC scan: resultsscan: results

Total No of Total No of teleconsultationteleconsultation

TELEMACO(2009-2010)

Stroke Cranial Trauma

6879

Patients mean age (y)Male

67 ±1775 (51%)

To send in other hospital (before teleconsultation)After teleconsultation

78 (53%)19 (18%)