SIBO PROTOCOL
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© 2018, Naturo Aid Pharmaceutical Inc. SIBO PROTOCOL Introduction Causes of SIBO Do You Have SIBO? A Checklist Diagnostic Tests SIBO Treatment Algorithm Relapse Prevention SIBO Product Index 1 2 3 5 7 9 11
Transcript of SIBO PROTOCOL
© 2018, Naturo Aid Pharmaceutical Inc.
SIBO PROTOCOL
Introduction
Causes of SIBO
Do You Have SIBO? A Checklist
Diagnostic Tests
SIBO Treatment Algorithm
Relapse Prevention
SIBO Product Index
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2
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IntroductionI
Small Intestine Bacterial Overgrowth (SIBO) is a condition in which abnormally high amounts of commensal bacteria are present in the small intestine. These bacteria ferment the food we eat and produce gases (predominantly hydrogen, methane, and hydrogen sulfide), which result in symptoms characteristic of Irritable Bowel Syndrome (IBS) such as abdominal distension, flatulence, eructations, acid reflux, diarrhea and/or constipation.
The bacterial overgrowth can also result in nutrient deficiencies due to malabsorption, contribute to intestinal hyperpermeability (“leaky gut”), and promote systemic inflammation, which may consequently lead to the more serious chronic diseases that damage vasculature. In fact, studies have shown that people tested positive for SIBO had increased risks in coronary artery disease [12] and deep vein thrombosis [13], and more serious complications from diabetes [14] and kidney disease [15].
Studies have demonstrated that SIBO may be the underlying cause of symptoms in 50 – 84% of IBS cases, and eradication of the bacterial overgrowth results in significant reduction in these symptoms. SIBO is also now recognized as causative or associated with myriad of conditions, ranging from rosacea and GERD to fibromyalgia and Parkinson’s disease.
Normally the small intestine has low bacteria counts, which are kept low through the following mechanisms:• AbovetheSmallIntestine:Hydrochloric acid in the stomach prevents overgrowth• WithintheSmallIntestine:
ο Pancreatic and brush-border enzymes → break down complex carbohydrate and promote absorption → reduce nutrient availability for bacteria
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Causes of SIBO
ο Bile acids and pancreatic enzymes prevent overgrowth ο Intact gastrointestinal immune function (ie. IgA)
• BelowtheSmallIntestine: Ileocecal (IC) valve separates colon from the small intestine
• Migratingmotorcomplex(MMC): a neuromuscular activity periodically sweeps through to ‘cleanse’ the small intestine of the bacteria growth
It is important to be able to recognize the signs and symptoms of SIBO, when to run diagnostic tests, and the proper choice of treatment for each individual patient.
Causes of SIBO Bacterial overgrowth occurs when intestinal stasis gives bacteria the opportunity to proliferate locally. There are a number of different factors that can lead to the development of SIBO:
• Infectious Gastroenteritis: bacterial toxins (acute) and post-infectious autoimmunity can both compromise the integrity of the gut linings and MMC
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SIBO often develops following a bout of gastroenteritis (an estimated 7-31%ofGI infectionswill develop SIBO).
These bacteria (eg. Campylobacteri jejuni, E. coli, Clostridium spp.) secrete neurotoxins that impair nerve conduction and inactivate the MMC. Some other toxins (eg. CdtB), through molecular mimicry, can trigger autoimmunity and, consequently, damage the MMC.
Did You Know?
GOOD
BAD
Goo
d&Bad
Bacteria
lFlora
Bifidobacteria
Escherichia Coli
Lactobacilli
Campyloacter
Sacchromyces spp.
Clostridium Difficile
• Compromised Digestion: hypochlorhydria, pancreatic enzyme and/or bile insufficiency, Helicobacter pylori infection
• Neuropathy:complications of diabetes, Parkinsons’s disease, multiple sclerosis
• Iatrogenic:post-surgery, opiate medication, proton pump inhibitors/antacids
• Mechanical/Structural Dysfunction: strictures, adhesions, space-occupying lesions, congenital anatomical abnormalities, diverticulitis, gynecological conditions (eg. endometriosis, ovarian cysts), ileocecal valve dysfunction
• Others:hypothyroidism, chronic stress (sympathetic nerve dominance), low secretory IgA
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Do You Have SIBO? A ChecklistIII
Circle the score of the situation(s) that best describe your symptoms, and add them up to yield a score in the end.
QUESTIONS SCORES9. Are you lactose intolerant?
a. Yes 2
b. No 0
10. Doyouhavechronicanemia(ie.ironorB12deficient)with no apparent cause?a. Yes 2
b. No 0
11. HowoftendoyoubelchwithinanhourAFTERmeals?
a. Rarely 0
b. Occasionally (1-2 times a week) 1
c. More than 3 times a week 2
d. Almost every meal 4
12. Howoftendoyoufeelthatyouhaveaproblemwithpassing too much gas?a. Rarely or Never 0
b. 1-3 days/week 1
c. Everyday 2
13. Howoftendoyouhavegastroesophagealacidreflux(GERD)?a. Rarely or Never 0b. Occasionally (1-2 times a month) 1
c. Once a week 2
d. More than twice a week 3
14. Howoftendidyouhavefoul-smelling(eg.rotten-egg),and/orfloatingstool?
a. Rarely or Never 0b. Occasionally 1
c. 1-3 days/week 2
d. Everyday 3
15. Wereyouonanyofthemedicationsforstomachdiscomfortoracidreflux,suchasantacidsandprotonpump inhibitors?a. No 0
b. Yes 1
16. Doyouhavemultiplefoodsensitivities/intolerances?
a. No 0
b. Yes 3SUBTOTAL B:
QUESTIONS SCORES1. Howoftendidyouhavediscomfortorpainanywherein
your stomach/abdomen? (If your answer is NEVER, please skip to #3)a. Quite often (more than 3 times/week) 2b. Sometimes (about 1-2 times/week) 1c. Rarely or Never 0
2. How long have you had this discomfort?a. Less than 2 weeks 0
b. 2 weeks to 2 months 1c. More than 2 months 2
3. Howoftendoyouhaveloose/waterystool?a. Rarely or Never 0b. Occasionally 1c. 1-2 times/week 2
d. More than 3 times week 44. Doyouhaveconstipation?
a. Yes (< 4 bowel movements/week) 4
b. No 0
5. Howoftendoyouhavedifficultyhavingabowelmovement(straining,feelingthatyouhavenotfinished)?a. Rarely or Never 0
b. Occasionally 1
c. 1-2 times/week 2
d. More than 3 times/week 3
6. Howlongdoesitusuallytakeyoutofinishpassingstool?
a. Less than 5 minutes 0
b. 5-10 minutes 1
c. More than 10 minutes 3
7. Doyouhaveloose/waterystoolalternatingwithconstipation/hardstool?a. Yes 3
b. No 0
8. Howoftendidyoufeelbloatedaftermeals?
a. Rarely or Never 0
b. Occasionally (1-2 times a month) 1
c. About once a week 2
d. Almost everyday 4
SUBTOTAL A:
4
QUESTIONS SCORES17. Have you been diagnosed with any of the following
conditions?(Mayselectmorethanone) ο Celiac Disease 2
ο Hypothyroidism 3
ο IBS 4
ο H. pylori infection 2
ο IBD (Ulcerative Colitis or Crohn’s Disease) 1
ο Rosacea/acne rosacea 2
ο Diabetes 1
ο Scleroderma 1
ο Chronic fatigue syndrome/Fibromyalgia 2
ο Restless Leg Syndrome 2
ο Liver Cirrhosis 1
18. Haveyoubeenhavingdifficultlygainingweightdespitegoodappetite?a. No 0
b. Yes 2
19. What are your daily average stress levels on a scale of 1 to10(10beingthemoststressedyouhaveeverbeen)?a. 5 or less 0
b. 6-8 1
c. 9-10 2
20. Have you had these gut problems since a bout of gastroenteritis(ie.foodpoisoning,vomiting&diarrhea,traveller’sdiarrhea)?a. No 0
b. Yes 2
21. Haveyoubeenexperiencinganyofthefollowing:anxiety,depression,poorsleepquality/insomnia,moodswings,andirritability?a. No 0
b. Yes 2
SUBTOTAL C:
TOTAL(A+B+C):
III
SCORING:• Score19-73: SIBO highly likely• Score8-18:SIBO likely, but other conditions are also
possible• Score<8:Symptoms may not be due to SIBO, and other
conditions should be considered
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DiagnosticTests
Endoscopy&Culture
Endoscopy and culture is widely considered the gold standard for SIBO testing, as it directly detects the presence of bacteria in the small intestine. However, there are several limitations to this test.
Aside from being expensive and invasive, endoscopy only samples the proximal small intestine, potentially missing the diagnosis of distal overgrowth, which some researchers posit to be the more common type. Furthermore, anaerobic bacteria are not readily cultured, and there is potential for contamination from other mucous membranes.
And finally, there is no globally agreed upon cut-off for what is considered a positive test. Most studies consider levels of 105 cfu/mL (colony forming unit/milliliters) as positive results, while others consider the cut-off anywhere from 104 to 107 cfu/mL. For these reasons, endoscopy is not commonly employed in the clinical setting.
AntibodiestoBacterialCytoxins& Cytoskeletal Proteins
Testing for the presence of anti-bacterial cytoxins, such as anti-CdtB (cytolethal distending toxin B), and anti-cytoskeletal proteins (eg. anti-vinculin) can help rule in/out the potential association with post-infectious causes of SIBO.
CdtB is a potent exotoxin secreted by pathogenic bacteria such as Shigella, E.coli, Campytobacter jejuni, and Salmonella. It is involved in the break-down of intercellular junctions by disintegrating the cytoskeletal polymers of the enterocytes. CdtB is also a DNAase that can directly damage DNA and potentially cause neoplasm in affected cells.
The presence of anti-cytoskeletal proteins may indicate an autoimmune reaction towards the intercellular junctions as the result of molecular mimicry between bacterial cytoxins and cytoskeletal proteins.
While this test does not replace the lactulose breath test, it can be helpful to confirm if the SIBO is autoimmune in origin and monitor the integrity of intestinal linings as treatment progresses.
Breath Test
Breath testing is the most common and cost-effective diagnostic tool for SIBO. Bacteria produce hydrogen and methane gases as a by-product of fermentation, and these gases can be detected in a breath sample. While this is an indirect measure, it does give clinically useful information, such as which gases are present and roughly where they are located, and as such is the best clinical test for SIBO.
Substrates:There are a variety of substrates that can be used for detecting SIBO, including glucose, lactulose, and 14C (isotope) xylose. Glucose is readily absorbed in the proximal small intestine, so it is not useful for detecting distal SIBO. For this reason it is not recommended as an ideal substrate. Lactulose is a non-absorbable sugar that is readily fermented by intestinal bacteria. Because it is not absorbed, it traverses the length of both the small and large intestines, allowing for measurement of gas by-products produced along the length. Lactulose is the most commonly used substrate for breath testing.
SIBO can be measured both directly and indirectly. The direct test involves endoscopy and culture, while the more common breath test is an indirect measure.
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TestLength:Although some labs still offer a 2-hour test, it is best to perform a 3-hour test in order to assess the full length of the small and large intestines.
GasesMeasured:The breath test should measure the presence of both hydrogen and methane gases, as well as CO2 (for validating sample collections). Labs that only measure hydrogen are insufficient, as treatment approaches may vary depending on which gases are elevated.
Currently hydrogen sulfide gas is not detected using standard breath test labs.
TestPreparation:The breath test typically requires a 12-hour prep diet and a 12-hour fast. The prep diet is restricted to
IsGlucoseReallyMoreSensitivethanLactulose?
Some studies note that glucose has a higher sensitivity than lactulose in detecting SIBO. However, this is because it is compared to the ‘gold standard’ of endoscopy
and culture, which only detects the proximal SI. Glucose is readily absorbed so it also only detects the proximal SI, therefore leading to the perceived higher sensitivity.
white rice, poultry, meat, fish, eggs, hard cheeses, clear beef or chicken broth, oil, salt, and pepper; vegetables, fruits, and other carbohydrate-rich foods should be avoided. The rationale for a prep diet is to minimize the presence of fermentable foods in order to obtain a clear baseline. The following morning the patient would take a baseline sample and then consume the lactulose solution. They would then collect samples every 20 minutes for 3 hours.
Prep. Diet Fasting
0 12 hours 24 hours
Interpretations:
A rise in hydrogen of ≥20 p.p.m. by 120 minutes during SIBO breath test is considered positive. Methane levels ≥10 p.p.m. is considered methane-positive. For methane-positive patients, the clinician should take into account of the slowed GI transit time caused by methanogens, and therefore, might need to look at both methane & hydrogen levels beyond 120 minutes.
Limitations:While the 3-hour lactulose breath test is the best available, there are still limitations:
• Indirect measure for SIBO• No global consensus of what constitutes a positive result• Significant number of false positive and false negative results• May not detect presence of non-hydrogen or methane producing bacteria (eg. hydrogen-sulfide producing)• Inconvenient preparation prior to the test (ie. a 12-hour prep diet and a 12-hour fasting)
LimitationsofOrganicAcidsTest(OAT)
The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient’s overall health with many bio-markers.
Although it provides the evaluation of intestinal yeast and bacteria, OAT can only indirectly tell you if you have a bacterial overgrowth. It cannot tell you where the overgrowth is occurring, and thus can only be used as a preliminary test to assess health, NOT to be used to diagnose SIBO.
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SIBO Screening Medical History + SIBO Checklist
Lactulose SIBO Breath Test
IfPOSITIVE,starttreatment.
Option#1:
Microcidin® [p.14] – 1-2 caps TID CC for 6 weeks
Alliimin DR [p.11] (optional adjunct) – 1 cap TID for 6 weeks.
Option#3(Antibiotics):
H2-producers:• Rifaximin (550 mg TID) for 14 daysCH4/Mixed H2-CH4producers:• Rifixamin (550 mg TID) for 10 days• Neomycin (500 mg BID) or Metronidazole (250 mg
TID) for 10 daysS. boulardii [p.17]- 2 caps TID for 14 days
DietOption#1:
• SIBOSpecificFoodGuide• KetogenicDiet+LowFODMAP
ProkineticOption#1(Herbal):
Prokine [p.16] – 1 cap between lunch and dinner, 2 caps at bedtime
Repairing:GI-Restore®LF[p.12]– 1 cap TID
DietOption#2:
Avoid foods in the highest FODMAP category, with the help of Intolerase[p.13]–1capCC,BID-TID
ProkineticOption#2(Pharma.):
(oneofthefollowing)
Erythromycin – 50 mg HSLDN – 2.5- 5 mg HSPrucalopride – 0.5-1 mg HS
1)LowCarb&LowFODMAPDiet* *Protein: 30%; Carb: 30%; Fats (avocado, olive, coconut oils): 40%2)Supreme-PB30+DF(withoutFOS)(Probiotics)[p.18] – 1 cap BID3)BetaineHCl(ifpatienthashypochlorhydria)– ____ caps CC TID
Follow-up&Re-assess@3rd,6th,and9thmonths
ERADICATION PHASE(10daysto6weeks)
SIBO Treatment Algorithm
Option#2:
Microcidin®AF*[p.15] – 1-2 caps TID for 6 weeks*For garlic sensitive, H2-dominant patients
SymptomRemitted?
YESNO
(Optional) Re-do SIBO Breath Test
Negative
Positive
If Symptoms Relapse
(Optional) Liver cleanse to minimize die-offreaction (1-2 weeks prior to & continue through Eradication Phase):
Hepasylin [p.13] – 2-3 caps QD
Fortough-to-eradicatecases (ie. no symptom improvement during and/or after the anti-microbial treatments):BiofilmX [p.12] - 1 cap, 15-30 min. before meal, TID for the duration of the Eradication Phase
Clinical Pearl: Advise patients to pay attention to foods that they are sensitive to (ie. cause symptoms of relapse). Identify and avoid/limit the intake of those foods.
AdaptedFromDr.Siebecker’sSIBOTreatmentAlgorithm.Reference: Siebecker A, Sandberg-Lewis S. Small Intestine Bacterial Overgrowth: Often-Ignored Cause of Irritable Bowel Syndrome. Townsend Lett. 2013;(February/March), p85-91. http://www.townsendletter.com/FebMarch2013/ibs0213.html
Consider other co-existing conditions (whilecontinuingtoRecoveryPhase), such as: yeast overgrowth (SIFO), endometriosis, peritoneal space-occupying lesions
ForHypochlorhydria
Betaine HCl – ____caps CC TID
REMISSION PHASE (FollowupQ3M)
RECOVERY PHASE(6months)
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Prep.Phase(1-2weeks):•Hepasylin - 2 caps QD. Total: 1 bottleEradicationPhase(6weeks):•Microcidin® - take 2 caps, TID, CC.
Total: 3 bottles•BiofilmX - take 1 cap, TID, 15-30 min.
before meal. Total: 2 bottlesRecoveryPhase(6months):•Prokine - take 1 cap between lunch &
dinner, and 2 caps at bedtime (3 caps/ day). Total: 4 bottles
•GI-Restore®LF - take 1 cap AC, TID. Total: 6 bottles
• Intolerase - take 1 cap CC, TID. Total: 6 bottles
•Betaine HCl - take 1 cap CC, TID. Total: 3 bottles
RemissionPhase(3months):• Supreme-PB30+DF(withoutFOS) - take
1 cap BID. Total: 3 bottles•Betaine HCl - take 1 cap CC, TID.
Total: 2 bottles
SamplePrescription#1Prep.Phase(1-2weeks):•Hepasylin - 2 caps QD. Total: 1 bottle EradicationPhase(10days):• Rifaximin - take 550 mg, TID• Metronidazole - take 250 mg, TID (CH4)•BiofilmX - take 1 capsule, TID, 15-30 min.
before meal. Total: 1 bottle•S. boulardii - take 2 capsules, TID with
antibiotics. Total: 2 bottlesRecoveryPhase(6months):• Prucalopride - take 0.5-1 mg HS. •Betaine HCl - take 1 cap CC, TID.
Total: 3 bottles•GI-Restore®LF - take 1 cap, TID.
Total: 3 bottlesRemissionPhase(3months):• Supreme-PB30+DF(withoutFOS) - take 1
cap BID. Total: 3 bottles•Betaine HCl - take 1 cap CC, TID.
Total: 2 bottles
SamplePrescription#2
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HighRecurrenceRate-AChallengeforBothPatients&DoctorsOne study showed that the recurrence rates of SIBO were 12.6% at 3 months, 27.5% at 6 months, and 43.7% at 9 months after successful antibiotic treatment.[6] Clinically, common SIBO relapse timeframes are about 2.5 months or even shorter unless the underlying causes are treated.
There are many underlying causes for SIBO recurrences, such as old age, chronic use of proton pump inhibitors (PPIs)[6], metabolic syndrome [7], immune dysfunction (eg. post-infectious autoimmunity), chronic neuro-degenerative diseases, and inability to comply with dietary changes.
Enhance Dietary Compliance
Poor compliance is a common theme in all SIBO-specific diets (eg. low-FODMAP diet), especially when patients are required to stay on such diets beyond 3 months. Additionally, there is often a lot of anxiety and stress associated with the regimen, which can potentially negate all the beneficial effects from the diet because stress and anxiety suppress our digestion and gut motility. [9] Also, any undigested carbohydrates can become the fuel to further feed the bacterial overgrowth and exacerbate SIBO symptoms.
To prevent SIBO recurrences, not only do we need to reduce FODMAP availability in our diet, but also ensure timely & complete digestion of carbohydrates because any partially digested carbohydrates can further feed the bacterial overgrowth present in the duodenum and proximal part of the jejunum.
Most digestive enzyme supplements can only cover 10-20% of estimated daily intakes of common FODMAPs, which is not enough to prevent SIBO recurrence. Intolerase [p.13], on the other hand, is formulated to reach the target of covering 70- 100% of daily FODMAP intakes. It provides an easy-to-comply alternative to low FODMAP diets and eases the stress and anxiety associated with foods during the SIBO recovery phase.
Minimize Bacterial Survival
Incorporating betaine hydrochloride with each meal, especially in those with suspected hypochlorhydria, can greatly reduce the chance of bacteria survival in the stomach and the duodenum.
Bitter herbs may also be used to promote digestive juice production (ie. stomach acid, bile, and pancreatic enzymes) to limit bacterial growth in proximal small intestine.
ImprovePsychosomaticAspectsofSIBO
Despite the fact that SIBO is an ‘organic’ disease, there is no denying its psychosomatic association.
Our mood and mental status can affect the activities of our enteric nervous system (ENS) via the autonomic nervous system (ANS) – namely sympathetic (SNS) and parasympathetic nervous systems (PNS).
The PNS is responsible for stimulation of the “rest-and-digest” or “feed-and-breed” activities including sexual arousal, urination, digestion and defecation. When there is a stress/alarm (eg. fight-or-flight) situation, our SNS will become activated to override the PNS and ENS andinhibitallGIactivities(i.e.peristalsisandMMCfunction;secretionsofstomachacid,mucus,enzymes,andbile)[9]. Therefore, when people are under stress, they will often have symptoms of indigestion, nausea/vomiting, and constipation/diarrhea.
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Herbal adaptogens (ie. Adrenergyn® [p.11]) and calmatives (ie. Resolaxin [p.16]) are great at assisting the body with shifting from the SNS-dominant state to the PNS-dominant state to help restore the MMC function of the gut.
Implementing PNS-stimulating activities, such as meditation, yoga, and breathing exercises, can also promote the PNS state. In addition, there are specific exercises that can directly stimulate the vagal nerve, which in turn can help shift the ANS from SNS to PNS: gargling, singing, swallowing (ie. drinking in small sips).
Addressing the Autoimmune Components of SIBO
Some SIBO cases, especially chronically recurrent ones, might be of unclear autoimmune origins. The current consensus attributes the history of post-bacterial gastroenteritis to be the main cause of autoimmune SIBO.[8] As aforementioned in the ‘Diagnostic Testing’ [p.5], bacteria like Shigella, E. coli, Campylobacter jejuni, and Salmonella are known to release cytotoxins (ie. cytolethal distending toxin B [CdtB]) into the enterocytes, disrupting the actin filaments and intercellular junctions [10], and directly damaging the DNA’s.[11]
Furthermore, through CdtB’s molecular mimicry to the cytoskeletal proteins of the enterocytes (ie. vinculin, zonulin, actin), these bacteria could cause a cascade of immune response attacking both the cytotoxins (ie. antibodies) and the cytoskeleton (ie. auto-antibodies) and continue to destroy the entero-linings at a much greater extent even after the pathogens were eradicated. As the damage continues to occur, the gut MMC function cannot be restored, consequently causing the recurrence of SIBO.
Once the autoimmune origin of SIBO is confirmed via anti-CdtB and anti-vinculin testing, the following multi-faceted approaches should be considered ontopoftheRecoveryPhaseoftheSIBO-specificprotocols:
• Mitochondrial Support (Neuromin [p.15])
• Anti-inflammatory (Verlusan+[p.18], EPA & DHA): reduce tissue damage and allow repair and regeneration
• Vitamin D3 (Liqui-D3[p.14] 1000 IU/drop): modulate immune function & regulate gut flora
• Probiotics (Supreme-PB30+DF[p.18]): form barriers to pathogens and modulate immune & metabolic functions
Reference:1. Khoshini R, Dai SC, Lezcano S, Pimentel M. A systematic review of diagnostic tests for small intestinal bacterial overgrowth. Dig Dis Sci. 2008; 53(6):1443-1454. 2. Pimentel, Mark, et al. “Development and validation of a biomarker for diarrhea-predominant irritable bowel syndrome in human subjects.” PloS one 10.5 (2015):
e0126438.3. Shah ED, Basseri RJ, Chong K, Pimentel M. Abnormal breath testing in IBS: a meta-analysis. Dig Dis Sci. 2010;55(9):2441-2449.4. Eisenmann A, Amann A, Said M, et al. Implementation and interpretation of hydrogen breath tests. J Breath Res. 2008;2(4):046002.5. Banik, Gourab Dutta, et al. Hydrogen sulphide in exhaled breath: a potential biomarker for small intestinal bacterial overgrowth in IBS. J Breath Research (2016): 026010. 6. Lauritano EC et al. Small intestinal bacterial overgrowth recurrence after antibiotic therapy. Am J Gastroenterol. (2008). 103(8): 2031-5.7. Fialho A, Fialho A, Thota P, McCullough AJ, Shen B. SIBO is associated with non-alcoholic fatty liver disease. J Gastrointestin Liver Dis. (2016). 25(2): 159-65.8. Wang JB, Lu SH, Zhao SJ. Post-infectious and non post-infectious irritable bowel syndrome: a comparative study. Pak J Med Sci. (2016). 32(1): 116-119.9. Tougas G. The autonomic nervous system in functional bowel disorders. Gut 2000. 47(4). http://gut.bmj.com/content/47/suppl_4/iv78.full10. Mendez-Olvera ET, Bustos-Martinez JA, Lopez-Vidal Y, Verdugo-Rodriguez A, Martinez-Gomez D. Cytolethal distending toxin from Campylobacter jejuni requires the
cytoskeleton for toxic activity. Jundishapur J Microbiol. (2016). 9(10):e35591.11. Bezine E, Vignard J, Mirey The cytolethal distending toxin effects on mammalian cells: a DNA damage perspective. Cells. (2014). 3(2):392-615.12. Fialho A et al. Association between SIBO by glucose breath test and CAD. Dig Dis Sci. (2018). 63(2):412-421.13. Fiahlo A et al. Association between SIBO and deep vein thrombosis. Gastroenterol Rep (Oxf). (2016). 4(4):299-303.14. Adamska A et al. SIBO in adults patients with type 1 diabetes: its prevalence and relationship with metabolic control and the presence of chronic complications of the
disease. Pol Arch Med Wewn. (2016). 126(9):628-634.15. Vanholder R, Glorieux G. The intestine and the kidneys: a bad marriage can be hazardous. Clin Kidny J. (2015). 8(2): 168-179.
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Acknowledgement: Special thanks to Dr. Allison Siebecker (ND), Dr. Christine Chen (ND), Dr. Joseph Cheng (ND), Dr. Charles Liu (ND), and Dr. Tomah Philips (ND) for their contributions of clinical expertise and review of this protocol.
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SIBO Product IndexVII
Adrenergyn®
Adrenergyn® contains a synergized ratio of adaptogenic herbs and vitamin B5 for patients with HPA-axis dysfunction and debility or during convalescence.
•Contains Cs-4 strain of Codyceps sinensis, the most extensively studied strain shown to enhance ATP generation and modulate cortisol level under stress.
•Clinically proven herbal remedies to increase the oxygen utilization in the body, scavenge free radicals that cause oxidative stress, and regulate the adrenal functions.
•Useful in restoring circadian rhythm, improving restless sleep, tiredness, declined cognitive ability, and weakened immune function caused by prolonged stress.
Ingredients (per capsule):(Each capsule contains 4070 mg Dried Herb Equivalent)Rhodiola Extract 10:1 (Rhodiola rosea) ....................................... 75 mg (root) (3% rosavins, 1% salidroside) (equivalent to 750 mg of dried herb)Cordyceps Cs-4 Extract 8:1 (Cordyceps sinensis) .....................200 mg (mycelium) (7% cordycepic acid) (equivalent to 1600 mg of dried herb)Eleuthero Extract 10:1 (Eleutherococcus senticosus) .................. 70 mg (root) (0.8% eleutherosides) (equivalent to 700 mg of dried herb)Ashwagandha Extract 6:1 (Withania somnifera) ....................... 170 mg (root) (7% withanolides) (equivalent to 1020 mg of dried herb)Vitamin B5 (from d-calcium pantothenate) ................................ 10 mg
Non-medicinal Ingredients: Silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 3 capsules daily, preferably before meals, or as directed by a health care practitioner. Consult a health care practitioner for use beyond 1 month.
Adrenal Support for HPA-Axis Dysfunction
Improves mental and physical performanceafter periods of mental or physical exertion.
Améliorer mentale et la performance physique après des périodes de la santé mentale ou l’effort physique.
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1)...
......
......
......
......
......
....7
0 m
g
(Ele
uthe
roco
ccus
senti
cosu
s) (r
oot/
raci
ne) (
0.8%
ele
uthe
rosid
es)
(e
quiv
alen
t to/
équ
ival
ent à
700
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
Ashw
agan
dha
Extr
act/
Ext
rait
d'As
hwag
andh
a (6
:1)..
......
......
......
....1
70 m
g
(With
ania
som
nife
ra) (
root
/rac
ine)
(7%
with
anol
ides
)
(equ
ival
ent t
o/ é
quiv
alen
t à 1
020
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
Vita
min
B5/
Vita
min
e B5
......
......
......
......
......
......
......
......
......
......
......
..10
mg
(fr
om d
-cal
cium
pan
toth
enat
e/de
d-p
anto
thén
ate
de c
alci
um)
Non
-med
icin
al In
gred
ient
s/ In
gréd
ient
s Non
-méd
icin
aux:
Sili
con
diox
ide/
dio
xyde
de
silic
ium
, L-le
ucin
e, p
ullu
lan/
hyp
rom
ello
se (c
apsu
le)
Sugg
este
d U
se/
U�l
isa�
on S
uggé
rée:
Ad
ults
- Ta
ke 3
cap
sule
s da
ily, p
refe
rabl
y be
fore
mea
ls, o
r as
dire
cted
by
your
hea
lth c
are
prac
��on
er. C
onsu
lt a
heal
th c
are
prac
��on
er fo
r us
e be
yond
2 w
eeks
./ A
dulte
s - P
rend
re 3
cap
sule
s pa
r jo
ur, p
réfé
rabl
emen
t av
ant
les
repa
s, o
u se
lon
les
reco
mm
anda
�ons
de
votr
e pr
a�ci
en d
e sa
nté.
Con
sulte
z un
prac
�cie
n de
la sa
nté
pour
une
u�l
isa�o
n co
n�nu
elle
au
-del
à de
2 se
mai
ne.
Cau�
on/
Mis
e en
Gar
de:
Do n
ot u
se i
f yo
u ha
ve h
igh
bloo
d pr
essu
re.
Cons
ult
a he
alth
car
e pr
ac��
oner
prio
r to
use
if yo
u ar
e pr
egna
nt o
r bre
as�e
edin
g; if
you
hav
e an
y ty
pe o
f ac
ute
infe
c�on
; if
you
are
taki
ng a
n�bi
o�cs
, an�
hype
rten
-siv
es, a
n�-p
sych
o�cs
and
/or b
lood
thin
ning
med
ica�
on; o
r/an
d if
you
are
unde
rgoi
ng th
erap
y fo
r dia
bete
s. C
onsu
mp�
on w
ith a
lcoh
ol, o
ther
dru
gs
or n
atur
al h
ealth
pro
duct
s with
seda
�ve
prop
er�e
s is n
ot re
com
men
ded.
/ N
e pa
s u�
lisé
en c
as d
'hyp
erte
nsio
n ar
térie
lle. C
onsu
lter
votr
e pr
a�ci
en
de s
anté
ava
nt l’
u�lis
a�on
si v
ous
êtes
enc
eint
e ou
si v
ous
alla
itez;
si v
ous
pren
ez d
es m
édic
amen
ts te
ls le
s an
�bio
�que
s, le
s an
�-ps
ycho
�que
s, le
s hy
pote
nseu
rs,
les
méd
icam
ents
pou
r éc
lairc
ir le
san
g et
/ou
d’au
tres
m
édic
amen
ts
pour
le
di
abèt
e.
La
cons
omm
a�on
d’
alco
ol,
d’au
tres
dr
ogue
s et
/ou
prod
uits
nat
urel
s au
x pr
oprié
tés
séda
�ves
n’e
st p
as
reco
mm
ande
r.
Stor
e at
ro
om
tem
pera
ture
aw
ay
from
he
at
and
moi
stur
e (<
30o C/
<60%
RH).
Plea
se fi
nish
con
sum
ing
the
prod
uct
with
in 6
0 da
ys
a�er
ope
ning
. Do
not
use
if
cap
seal
is
brok
en.
Keep
out
of
reac
h of
ch
ildre
n./
Cons
erve
r à
la te
mpé
ratu
re a
mbi
ante
loin
de
la c
hale
ur e
t de
l’h
umid
ité
(<30
o C/<6
0%RH
). S’
il vo
us
plaî
t te
rmin
er
le
prod
uit
est
cons
omm
é da
ns le
s 60
jour
s apr
ès o
uver
ture
. Ne
pas u
�lise
r si l
e sc
eau
de
sécu
rité
est b
risé
ou m
anqu
ant.
Gar
dez h
ors d
e po
rtée
des
enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.M
aple
Rid
ge, B
.C.,
V2X
8G1,
Can
ada
| w
ww
.vita
aid.
com
84 Vegetarian Capsules NPN 80028474
Adrenergyn®
Vegan
Form
ulas
Form
ules
Veg
an Improves mental and physical performance
after periods of mental or physical exertion.
Améliorer mentale et la performance
physique après des périodes de la santé
mentale ou l’effort physique.
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
caps
ule)
:
(Eac
h ca
psul
e co
ntai
ns 4
070
mg
Drie
d He
rb E
quiv
alen
t/
Cha
que
caps
ule
con�
ent 4
070
mg
équi
vale
nt h
erbe
séch
és)
Rhod
iola
Ext
ract
/ Ext
rait
de R
hodi
ola
(Rho
diol
a ro
sea)
(10:
1)...
......
..75
mg
(ro
ot/r
acin
e) (3
% ro
savi
ns, 1
% sa
lidro
side)
(e
quiv
alen
t to/
équ
ival
ent à
750
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
Cord
ycep
s Ext
ract
/ Ext
rait
de C
ordy
ceps
(8:1
).....
......
......
......
......
....2
00 m
g
(C
ordy
ceps
sine
nsis
Cs-4
) (m
ycel
ium
/myc
éliu
m)
(7
% co
rdyc
epic
acid
/ acid
e co
rdyc
epic)
(e
quiv
alen
t to/
équ
ival
ent à
160
0 m
g dr
ied
herb
/ de
herb
e sé
chée
)
Eleu
ther
o Ex
tract
/ Ext
rait
d’Él
euth
éro
(10:
1)...
......
......
......
......
......
....7
0 m
g
(E
leut
hero
cocc
us se
ntico
sus)
(roo
t/ra
cine)
(0.8
% e
leut
hero
sides
)
(e
quiv
alen
t to/
équ
ival
ent à
700
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
Ashw
agan
dha
Extra
ct/ E
xtra
it d'
Ashw
agan
dha
(6:1
).....
......
......
......
.170
mg
(W
ithan
ia so
mni
fera
) (ro
ot/r
acin
e) (7
% w
ithan
olid
es)
(e
quiv
alen
t to/
équ
ival
ent à
102
0 m
g dr
ied
herb
/ de
herb
e sé
chée
)
Vita
min
B5/
Vita
min
e B5
......
......
......
......
......
......
......
......
......
......
......
..10
mg
(fr
om d
-cal
cium
pan
toth
enat
e/de
d-p
anto
thén
ate
de ca
lcium
)
Non-
med
icina
l Ing
redi
ents
/ Ing
rédi
ents
Non
-méd
icina
ux: S
ilico
n
diox
ide/
dio
xyde
de
silici
um, L
-leuc
ine,
pul
lula
n/ h
ypro
mel
lose
(cap
sule
)
Sugg
este
d Us
e/ U
�lisa
�on
Sugg
érée
:
Adul
ts -
Take
3 c
apsu
les
daily
, pre
fera
bly
befo
re m
eals,
or a
s di
rect
ed b
y
your
hea
lth c
are
prac
��on
er. C
onsu
lt a
heal
th c
are
prac
��on
er fo
r us
e
beyo
nd 2
wee
ks./
Adul
tes
- Pre
ndre
3 c
apsu
les
par j
our,
préf
érab
lem
ent
avan
t le
s re
pas,
ou s
elon
les
reco
mm
anda
�ons
de
votr
e pr
a�cie
n de
sant
é. C
onsu
ltez u
n pr
ac�c
ien
de la
sant
é po
ur u
ne u
�lisa
�on
con�
nuel
le
au-d
elà
de 2
sem
aine
.
Cau�
on/ M
ise e
n Ga
rde:
Do n
ot u
se i
f yo
u ha
ve h
igh
bloo
d pr
essu
re.
Cons
ult
a he
alth
car
e
prac
��on
er p
rior t
o us
e if
you
are
preg
nant
or b
reas
�eed
ing;
if y
ou h
ave
any
type
of
acut
e in
fec�
on; i
f yo
u ar
e ta
king
an�
bio�
cs, a
n�hy
pert
en-
sives
, an�
-psy
cho�
cs a
nd/o
r blo
od th
inni
ng m
edica
�on;
or/
and
if yo
u ar
e
unde
rgoi
ng th
erap
y fo
r dia
bete
s. Co
nsum
p�on
with
alco
hol,
othe
r dru
gs
or n
atur
al h
ealth
pro
duct
s with
seda
�ve
prop
er�e
s is n
ot re
com
men
ded.
/
Ne p
as u
�lisé
en
cas
d'hy
pert
ensio
n ar
térie
lle. C
onsu
lter v
otre
pra
�cie
n
de s
anté
ava
nt l’
u�lis
a�on
si v
ous
êtes
enc
eint
e ou
si v
ous
alla
itez;
si vo
us
pren
ez d
es m
édica
men
ts te
ls le
s an�
bio�
ques
, les
an�
-psy
cho�
ques
, les
hypo
tens
eurs
, le
s m
édica
men
ts p
our
écla
ircir
le s
ang
et/o
u d’
autr
es
méd
icam
ents
pou
r le
dia
bète
. La
con
som
ma�
on d
’alco
ol,
d’au
tres
drog
ues
et/o
u pr
odui
ts n
atur
els
aux
prop
riété
s sé
da�v
es n
’est
pas
reco
mm
ande
r.
Stor
e at
ro
om
tem
pera
ture
aw
ay
from
he
at
and
moi
stur
e
(<30
oC/
<60%
RH).
Plea
se fi
nish
con
sum
ing
the
prod
uct
with
in 6
0 da
ys
a�er
ope
ning
. Do
not
use
if ca
p se
al is
bro
ken.
Kee
p ou
t of
rea
ch o
f
child
ren.
/ Co
nser
ver à
la te
mpé
ratu
re a
mbi
ante
loin
de
la c
hale
ur e
t de
l’hum
idité
(<3
0oC/
<60%
RH).
S’il
vous
pla
ît te
rmin
er l
e pr
odui
t es
t
cons
omm
é da
ns le
s 60
jour
s apr
ès o
uver
ture
. Ne
pas u
�lise
r si le
scea
u de
sécu
rité
est b
risé
ou m
anqu
ant.
Gard
ez h
ors d
e po
rtée
des
enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.
Map
le R
idge
, B.C
., V2
X 8G
1, C
anad
a |
ww
w.vi
taai
d.co
m
84 Vegetarian CapsulesNPN 80028474
Adrenergyn® Vegan Fo
rmula
s
Form
ules
Vegan
Dosage Form: 84 Vegetarian Capsules
Alliimin DR
Alliimin DR is a potent allicin concentrate from freeze-dried fresh garlic, encapsulated in a pH-controlled releasing (ie. stomach friendly) vegetarian capsule.
•Standardized and lab-certified to contain 20,000 mcg alliin per gram (yielding 10,000 mcg allicin).
•Broad spectrum antimicrobial effects. Clinically proven to relieve the symptoms associated with upper respiratory tract infections, as well as other microbial infections.
•Helps to improve hyperlipidemia and maintain cardiovascular health.
Ingredients (per capsule):Garlic (Allium sativum) (bulb).....................................................500 mg Standardized to contain:
Allicin .............5,000 mcg (from 10,000 mcg of Alliin)
Non-medicinal Ingredients: Certified organic apple fiber, L-leucine, hypromellose/pullulan (capsule)
Suggested Use: Adults - Take 1-2 capsules daily with food, or as directed by your health care practitioner. For prolonged use, consult a health care practitioner.
Dosage Form: 84 Vegetarian Capsules
Delayed-Release Garlic Extract
12
BiofilmX
• Serrapeptase - a potent mucolytic enzyme that help reduce the inhibitory effects of bacterial biofilms and decrease chronic inflammation.
• Systemic fibrinolytic proteases and polysaccharide-digesting enzymes to help breakdown the integrity of biofilms and their adhesion to target tissues.
• Alpha lipoic acid - a sulfur-containing compound known to disrupt biofilms and provide antioxidant protection to the host.
• Delayed-release encapsulation (FREE of phthalate - commonly found in enteric coating) to help bypass the stomach and retain the bioactivity of the enzymes.
Clinical Applications:
• Decrease inflammatory edema.
• Accelerates the elimination of sputum, pus and hematoma.
• Enhance pathogen eradication of antibiotics/ antimicrobials.
Ingredients (per capsule):Serrapeptase (from Serratia marcescens E-15) ..................... 30,000 SUProtease (from Aspergillus oryzae) .......................................15,000 HUTAlkaline Protease (*Nattozimes®) ...........................4,225 HUT (1,500 FU) (from Aspergillus oryzae & Aspergillus melleus) Xylanase (from Trichoderma longibrachiatum) ....................... 1,100 XU Pectinase (from Aspergillus niger) .........................................50 endo-P Beta-Glucanase (from Trichoderma longibrachiatum) .............30 BGU Glucoamylase (from Aspergillus niger) ......................................25 AGU Hemicellulase (from Aspergillus niger) ................................. 4,000 HCU Cellulase (from Aspergillus niger) ...............................................500 CU Alpha Lipoic Acid ......................................................................200 mg
*Nattozimes®is a registered trademark of National Enzyme Company®
Non-medicinal Ingredients: Silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 1 capsule with meal, 3 times a day, or as directed by a health care practitioner. Consult a health care practitioner for use beyond 4 months.
814741
00139
0
Enteric Release (Free of Pthalate)Biofilm Disrupting FormulaWith proteolytic & mucolytic enzymes to help break down mucous
Sortie Entérique (Sans Pthalate)Formule perturbatrice de BiofilmAvec des enzymes protéolytique et mucolytiques pour aider à dissoudre le mucus
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
cap
sule
):Se
rrap
epta
se (f
rom
/de
Serr
atia
mar
cesc
ens E
-15)
......
......
......
....3
0,00
0 SU
Prot
ease
(fro
m/d
e As
perg
illus
ory
zae)
......
......
......
......
......
......
..15,
000
HUT
Alka
line
Prot
ease
(Na�
ozim
es®)
......
......
......
......
......
..1,5
00 F
U (4
,225
HU
T)
(from
/de
Aspe
rgill
us m
elle
us &
Asp
ergi
llus o
ryza
e)Xy
lana
se (f
rom
/de
Tric
hode
rma
long
ibra
chia
tum
).....
......
......
......
1,10
0 XU
Pec�
nase
(fro
m/d
e As
perg
illus
nig
er)..
......
......
......
......
......
......
...50
End
o-P
Beta
-Glu
cana
se (f
rom
/de
Tric
hode
rma
long
ibra
chia
tum
).....
......
....3
0 BG
UGl
ucoa
myl
ase
(from
/de
Aspe
rgill
us n
iger
).....
......
......
......
......
......
....2
5 AG
UHe
mic
ellu
lase
(fro
m/d
e As
perg
illus
nig
er)..
......
......
......
......
......
..4,0
00 H
CUCe
llula
se (f
rom
/de
Aspe
rgill
us n
iger
).....
......
......
......
......
......
......
......
500
CUAl
pha
Lipo
ic A
cid/
Aci
de a
lpha
-lipo
ïque
......
......
......
......
......
......
......
.200
mg
*Na�
ozim
es®
is a
regi
ster
ed tr
adem
ark
of N
a�on
al E
nzym
e Co
mpa
ny®/
N
a�oz
imes
® es
t une
mar
que
dépo
sée
de N
a�on
al E
nzym
e Co
mpa
ny®
Non
-med
icin
al In
gred
ient
s/ In
gréd
ient
s Non
-méd
icin
aux:
Si
licon
dio
xide
/ dio
xyde
de
silic
ium
, L-le
ucin
e, h
ypro
mel
lose
(cap
sule
)Su
gges
ted
Use
/ U
�lis
a�on
Sug
géré
e:
Adul
ts –
Tak
e 1
caps
ule,
3 �
mes
a d
ay, o
r as
dire
cted
by
a he
alth
care
pr
ac��
oner
. Con
sult
a he
alth
car
e pr
ac��
oner
for u
se b
eyon
d 4
wee
ks./
Ad
ulte
s -
Pren
dre
1 ca
psul
e, 3
fois
par
jour
, ou
selo
n le
s in
dica
�ons
de
votr
e pr
a�ci
en d
e so
ins d
e sa
nté.
Con
sulte
r un
pra�
cien
de
soin
s de
sant
é si
l'usa
ge se
pro
long
e au
-del
à de
4 se
mai
nes .
Cau�
on/
Mis
e en
Gar
de:
Do n
ot u
se if
you
are
pre
gnan
t or b
reas
�eed
ing.
Alle
rgy
has
been
kno
wn
to o
ccur
; in
whi
ch ca
se, d
iscon
�nue
use
. Con
sult
a he
alth
care
pra
c��o
ner
prio
r to
use
if
you
have
a g
astr
oint
es�n
al l
esio
n/ul
cer,
are
taki
ng
an�c
oagu
lant
or a
n�-in
flam
mat
ory
med
ica�
on, o
r are
hav
ing
surg
ery;
or
if yo
u ha
ve
diab
etes
. Di
scon
�nue
us
e an
d co
nsul
t a
heal
thca
re
prac
��on
er i
f yo
u ex
perie
nce
swea
�ng,
pal
enes
s, c
hills
, he
adac
he,
dizz
ines
s and
/or c
onfu
sion
(ie. s
ympt
oms o
f low
blo
od su
gar)
./
Ne
pas
u�lis
er s
i vou
s êt
es e
ncei
nte
ou s
i vou
s al
laite
z. H
yper
sens
ibili
té,
telle
une
alle
rgie
, peu
t se
man
ifest
er. S
i tel
est
le c
as, c
esse
r l'u
�lisa
�on.
Co
nsul
ter
un p
ra�c
ien
de s
oins
de
sant
é av
ant
d'en
faire
l'us
age
si vo
us
avez
de
s lé
sions
ga
stro
-inte
s�na
les/
ulcè
res,
si
vous
pr
enez
de
s an
�coa
gula
nts
ou d
es a
n�-in
flam
mat
oire
, ou
si
vous
dev
ez s
ubir
une
chiru
rgie
; ou
si vo
us a
vez
le d
iabè
te. S
i vou
s dé
velo
ppez
des
sym
ptôm
es
tels
que
de la
tran
spira
�on,
de
la p
âleu
r, de
s fr
isson
s, d
es m
aux
de tê
te,
des
étou
rdiss
emen
ts
et/o
u de
la
co
nfus
ion,
ce
sser
l'u
�lisa
�on
et
cons
ulte
r un
pra�
cien
de
soin
s de
sant
é (c
ar c
es sy
mpt
ômes
peu
vent
êtr
e ca
usés
par
un
faib
le ta
ux d
e su
cre
dans
le sa
ng).
Stor
e at
ro
om
tem
pera
ture
aw
ay
from
he
at
and
moi
stur
e (<
30o C/
<60%
RH).
Plea
se fi
nish
con
sum
ing
the
prod
uct
with
in 6
0 da
ys
a�er
ope
ning
. Do
not
use
if c
ap s
eal i
s br
oken
. Ke
ep o
ut o
f re
ach
of
child
ren.
/ Co
nser
ver
à la
tem
péra
ture
am
bian
te lo
in d
e la
cha
leur
et d
e l’h
umid
ité
(<30
o C/<6
0%RH
). S’
il vo
us
plaî
t te
rmin
er
le
prod
uit
est
cons
omm
é da
ns le
s 60
jour
s apr
ès o
uver
ture
. Ne
pas u
�lise
r si l
e sc
eau
de
sécu
rité
est b
risé
ou m
anqu
ant.
Gard
ez h
ors d
e po
rtée
des
enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.M
aple
Rid
ge, B
.C.,
V2X
8G1,
Can
ada
| w
ww
.vita
aid.
com
84 Vegetarian Capsules NPN 80078777
BiofilmX
Vegan
Form
ulas
Form
ules
Veg
an
8
1
4
7
4
1
0
0
1
3
9
0
Enteric Release (Free of Pthalate)
Biofilm Disrupting Formula
With proteolytic & mucolytic enzymes to help
break down mucousSortie Entérique (Sans Pthalate)
Formule perturbatrice de Biofilm
Avec des enzymes protéolytique et mucolytiques
pour aider à dissoudre le mucus
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
caps
ule)
:
Serr
apep
tase
(fro
m/d
e Se
rrati
a m
arce
scen
s E-1
5)...
......
......
......
.30,
000
SU
Prot
ease
(fro
m/d
e As
perg
illus
ory
zae)
......
......
......
......
......
......
..15,
000
HUT
Alka
line
Prot
ease
(Na�
ozim
es®)
......
......
......
......
......
..1,5
00 F
U (4
,225
HUT
)
(fr
om/d
e As
perg
illus
mel
leus
& A
sper
gillu
s ory
zae)
Xyla
nase
(fro
m/d
e Tr
ichod
erm
a lo
ngib
rach
iatu
m)..
......
......
......
...1,
100
XU
Pec�
nase
(fro
m/d
e As
perg
illus
nig
er)..
......
......
......
......
......
......
...50
End
o-P
Beta
-Glu
cana
se (f
rom
/de
Trich
oder
ma
long
ibra
chia
tum
).....
......
....3
0 BG
U
Gluc
oam
ylas
e (fr
om/d
e As
perg
illus
nig
er)..
......
......
......
......
......
......
.25
AGU
Hem
icellu
lase
(fro
m/d
e As
perg
illus
nig
er)..
......
......
......
......
......
..4,0
00 H
CU
Cellu
lase
(fro
m/d
e As
perg
illus
nig
er)..
......
......
......
......
......
......
......
...50
0 CU
Alph
a Lip
oic A
cid/ A
cide
alph
a-lip
oïqu
e....
......
......
......
......
......
......
...20
0 m
g
*Na�
ozim
es®
is a
regi
ster
ed tr
adem
ark
of N
a�on
al E
nzym
e Co
mpa
ny®/
Na�
ozim
es®
est u
ne m
arqu
e dé
posé
e de
Na�
onal
Enz
yme
Com
pany
®
Non-
med
icina
l Ing
redi
ents
/ Ing
rédi
ents
Non
-méd
icina
ux:
Silic
on d
ioxid
e/ d
ioxy
de d
e sil
icium
, L-le
ucin
e, h
ypro
mel
lose
(cap
sule
)
Sugg
este
d Us
e/ U
�lisa
�on
Sugg
érée
:
Adul
ts –
Tak
e 1
caps
ule,
3 �
mes
a d
ay, o
r as
dire
cted
by
a he
alth
care
prac
��on
er. C
onsu
lt a
heal
th ca
re p
rac�
�one
r for
use
bey
ond
4 w
eeks
./
Adul
tes
- Pre
ndre
1 c
apsu
le, 3
fois
par
jour
, ou
selo
n le
s in
dica
�ons
de
votre
pra
�cie
n de
soin
s de
sant
é. C
onsu
lter u
n pr
a�cie
n de
soin
s de
sant
é
si l'u
sage
se p
rolo
nge
au-d
elà
de 4
sem
aine
s .
Cau�
on/ M
ise e
n Ga
rde:
Do n
ot u
se if
you
are
pre
gnan
t or b
reas
�eed
ing.
Alle
rgy
has b
een
know
n
to o
ccur
; in
whi
ch ca
se, d
iscon
�nue
use
. Con
sult
a hea
lth ca
re p
rac�
�one
r
prio
r to
use
if
you
have
a g
astro
inte
s�na
l le
sion/
ulce
r, ar
e ta
king
an�c
oagu
lant
or a
n�-in
flam
mat
ory
med
ica�o
n, o
r are
hav
ing
surg
ery;
or
if yo
u ha
ve
diab
etes
. Di
scon
�nue
us
e an
d co
nsul
t a
heal
thca
re
prac
��on
er i
f yo
u ex
perie
nce
swea
�ng,
pal
enes
s, ch
ills,
head
ache
,
dizz
ines
s and
/or c
onfu
sion
(ie. s
ympt
oms o
f low
blo
od su
gar).
/
Ne p
as u
�lise
r si v
ous
êtes
enc
eint
e ou
si v
ous
alla
itez.
Hype
rsen
sibili
té,
telle
une
alle
rgie
, peu
t se
man
ifest
er. S
i tel
est
le c
as, c
esse
r l'u
�lisa
�on.
Cons
ulte
r un
pra�
cien
de s
oins
de
sant
é av
ant d
'en
faire
l'us
age
si vo
us
avez
de
s lé
sions
ga
stro
-inte
s�na
les/
ulcè
res,
si vo
us
pren
ez
des
an�c
oagu
lant
s ou
des
an�
-infla
mm
atoi
re,
ou s
i vou
s de
vez
subi
r un
e
chiru
rgie
; ou
si vo
us a
vez l
e di
abèt
e. S
i vou
s dév
elop
pez d
es sy
mpt
ômes
tels
que
de la
tran
spira
�on,
de
la p
âleu
r, de
s fris
sons
, des
mau
x de
tête
,
des
étou
rdiss
emen
ts e
t/ou
de
la c
onfu
sion,
ces
ser
l'u�l
isa�o
n et
cons
ulte
r un
pra�
cien
de so
ins d
e sa
nté
(car
ces s
ympt
ômes
peu
vent
être
caus
és p
ar u
n fa
ible
taux
de
sucr
e da
ns le
sang
).
Stor
e at
ro
om
tem
pera
ture
aw
ay
from
he
at
and
moi
stur
e
(<30
o C/<6
0%RH
). Pl
ease
fini
sh c
onsu
min
g th
e pr
oduc
t w
ithin
60
days
a�er
ope
ning
. Do
not
use
if ca
p se
al is
bro
ken.
Kee
p ou
t of
rea
ch o
f
child
ren.
/ Co
nser
ver à
la te
mpé
ratu
re a
mbi
ante
loin
de
la c
hale
ur e
t de
l’hum
idité
(<3
0oC/
<60%
RH).
S’il
vous
pla
ît te
rmin
er l
e pr
odui
t es
t
cons
omm
é da
ns le
s 60
jour
s apr
ès o
uver
ture
. Ne
pas u
�lise
r si le
scea
u de
sécu
rité
est b
risé
ou m
anqu
ant.
Gard
ez h
ors d
e po
rtée
des
enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.
Map
le R
idge
, B.C
., V2
X 8G
1, C
anad
a |
ww
w.vi
taai
d.co
m
84 Vegetarian CapsulesNPN 80078777
BiofilmX
Vega
n Form
ulas
Form
ules V
egan
Dosage Form: 84 Vegetarian Capsules
BiofilmX combines multiple fibrinolytic & mucolytic enzymes to help breakdown biofilms and augment the efficacy of antimicrobial agents.
Biofilm Disrupting Formula
GI-Restore® LF
GI-Restore® LF is a Low FODMAP, gut-healing formula to help relieve inflammatory conditions of the GI tract and repair the linings of the stomach, the small intestine, and the colon via multiple mechanisms:
• Support intercellular tight junctions
• Promote mucus secretion in the stomach
• Anti-inflammatory and anti-histamine actions - ensure gut lining integrity and regulate acid secretion
• Promote proper tissue formation and regeneration
•Contain Butyrate (SCFA) to support Colonocytes & Colon Lining Integrity. SCFAs are derived from soluble fibers via bacterial fermentation, and can become deficient over long term Low FODMAP diet.
Ingredients (per 3 capsules):Zinc Carnosine .......................................................................... 150 mgCurcumin (from Curcuma longa) .............................................200 mg (root, rhizome) (*C3-Complex®)L-Glutamine ...............................................................................600 mgCayenne Extract 18:1 (Capsicum annuum) ...............................20 mg (fruit) (equivalent to 360 mg of dried herb) Quercetin (isolate) .....................................................................300 mgCalcium Butyrate ..................................................................... 300 mg
*C3-Complex®is a registered trademark of Sabinsa Corp.
Non-Medicinal Ingredients: Silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 1 capsule, 3 times a day, or as directed by a health care practitioner.
Dosage Form: 84 Vegetarian Capsules
Comprehensive Gut-Healing Formula for Low FODMAP Diet
13
Intolerase
Intolerase is an ultra-potent, broad-spectrum carbohydrase formula designed to break down fermentable carbohydrates and support post-eradication phase of SIBO treatment.
• Helps prevent SIBO and its recurrence.
• Easier-to-comply alternative to strict low FODMAP & elemental diets.
• Enzyme potencies are based on the estimated dietary intake of common FODMAPs in general population.
•Contains butyrate (SCFA) to support colonocytes & lining integrity.
Ingredients (per capsule):Alpha-Galactosidase (from Aspergillus niger) ........................925 GalULactase (from Aspergillus oryzae) ...........................................3,000 ALUAmylase (from Aspergillus oryzae)............................................8,109 DU (contains 7,709 bacterial amylase units)Glucoamylase (from Aspergillus niger) ....................................150 AGUPectinase (from Aspergillus niger) .........................................90 endo-PBeta-Glucanase (from Trichoderma longibrachiatum) ...........105 BGUHemicellulase (from Aspergillus niger) ............................... 20,000 HCUInvertase (from Aspergillus niger)......................................2,100 SumnerXylanase (from Trichoderma longibrachiatum) .......................1,650 XUMaltase (from Hordeum vulgare seed) ...................................... 300 DPProtease (from Aspergillus oryzae) .......................................15,000 HUTAcid Protease (from Aspergillus oryzae) .................................... 15 SAPU
Non-medicinal Ingredients: Calcium butyrate (250 mg), microcrystalline cellulose, silicon dioxide, L-leucine, pullulan/ hypromellose (capsule).
Suggested Use: Adults - Take 1 capsule with carbohydrate-rich meal, 2-3 times a day, or as directed by your health care practitioner. For prolonged use, consult a health care practitioner.
Dosage Form: 84 Vegetarian Capsules
“DigestYourIntolerances”forSIBO&Malabsorption
HepasylinHerbal Hepato-Protectant
Hepasylin is a comprehensive herbal liver tonic formula containing milk thistle, dandelion, artichoke and alpha lipoic acid to protect the hepatocytes and maintain healthy liver function.
•Contains milk thistle extract standardized by not only silymarins but also silybins–themostactivecompoundofsilymaringroup –toguaranteethemaximumliver-protectingeffect.
•Increases the reduced glutathione level in the liver, promotes bile flow, provides powerful antioxidants for cell protection, and enhances the detoxification process in the liver.
Ingredients (per capsule):(Each capsule contains 4120 mg Dried Herb Equivalent) Milk Thistle Extract 15:1 (Silybum marianum) .............................250 mg (seed) (80% silymarins, min. 30% silybins) (equivalent to 3750 mg dried herb)Dandelion Root Extract 4:1 (Taraxacum officinale) .....................20 mg (equivalent to 80 mg dried herb)Artichoke Leaf Extract 5:1 (Cynara scolymus) .............................50 mg (2.5% cynarin) (equivalent to 250 mg of dried herb)Licorice Root Extract 4:1 (Glycyrrhiza glabra) .............................. 10 mg (equivalent to 40 mg of dried herb)Alpha Lipoic Acid ........................................................................ 20 mg
Non-medicinal Ingredients: Certified organic apple fiber, silicon dioxide, L-leucine, pullulan/hypromellose (capsule)
Suggested Use: Adults - Take 1 capsule 2 times daily, or as directed by your health care practitioner.
Dosage Form: 120 Vegetarian Capsules
VII
14
Liqui-D3Vitamin D3 is known for its function in:
•Increasing calcium absorption in the gut for osteoporosis prevention.
•Modulating serotonin synthesis and release and improving mental health.
•Optimizing immune system and reducing the risk of metabolic syndrome.
Key Features:
•Utilize pure crystalline vitamin D3 as our starting material minimizing unnecessary non-medicinal ingredients.
•Use Medium Chain Triglycerides (MCT) from coconut as base - a much more stable source than PUFAs, such as corn or sunflower oil.
•Free of preservative or stabilizing agent, such as butylated hydroxytoluene (BHT).
•Laboratory-tested potency and stability from the first to the last drop.
Ingredients (per drop):Vitamin D3 (25 mcg) (cholecalciferol) .......................................1000 IU
Non-medicinal Ingredients: Medium chain triglycerides (MCT), natural flavor
Suggested Use: Take 1 drop per day, or as directed by a health care practitioner. Suitable for all age groups.
Dosage Form: 60 mL Liquid (~2100 servings)
•Coptis (Huang Lian) contains berberine as its main constituent. Coptis is the king herb for detoxification in Traditional Chinese Medicine, especially during infections and Liver Fire. In modern medicine, coptis by itself or combined with clove extract has been shown to inhibit fungal growth and candidiasis.
•Contains lab-standardized high allicin content from freeze-dried garlic concentrate. Allicin is a potent natural antibiotic that does not cause dysbiosis.
•Synergized with highly concentrated oregano extract, and caprylic acid for broad spectrum microcidal effect in prevention and eradication of microbial infections.
Ingredients (per capsule):Huang Lian Extract 12:1 (Coptis chinensis) ..................................60 mg (rhizome) (20% berberine) (equivalent to 720 mg dried herb)Garlic (Allium sativum) (bulb)..................................................... 240 mg (20,000 mcg alliin/g to yield 10,000 mcg allicin/g)Oregano Extract 23:1 (Origanum vulgare) ..................................40 mg (leaf) (30% carvacrol) (equivalent to 920 mg dried herb)*Clove Extract 3:1 (Syzygium aromaticum) .................................50 mg (flower bud) (30% volatile oil) (equivalent to 150 mg dried herb)
*Non-medicinal Ingredients: Magnesium caprylate, undecylenic acid, silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 1 capsule with meal, 2-3 times per day, or as directed by a health care practitioner.
Microcidin®
Microcidin® contains multiple antimicrobial ingredients with different mechanisms to inhibit and eradicate pathogenic microbes such as bacteria, virus, fungus (eg. Candida albican) and parasites.
Broad-Spectrum Anti-microbial FormulaHelps to relieve the symptoms associated with upper respiratory tract infections and catarrhal conditions.
À large spectre anti-microbien formulePour aider à soulager les symptômes associés à des infections respiratoires hautes et les conditions catarrhales.
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
cap
sule
):Co
p�s E
xtra
ct/ E
xtra
it de
Cop
�s (H
uang
Lia
n) (1
2:1)
......
......
......
.60
mg
(C
optis
chi
nens
is) (r
hizo
me)
(20%
ber
berin
e)
(equ
ival
ent t
o/ é
quiv
alen
t à 7
20 m
g dr
ied
herb
/ de
herb
e sé
chée
)Ga
rlic/
Ail
(Alli
um sa
tivum
) (bu
lb/ b
ulbe
).....
......
......
......
......
.....2
40 m
g
(10,
000
mcg
alli
cin/
g) (2
0,00
0 m
cg a
lliin
/g)
Ore
gano
Ext
ract
/ Ext
rait
d'or
igan
(23
:1) (
Orig
anum
vul
gare
).....
40 m
g
(leaf
/ feu
ille)
(30%
car
vacr
ol)
(e
quiv
alen
t to/
équ
ival
ent à
920
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
*Clo
ve E
xtra
ct/ E
xtra
it de
giro
fle (3
:1) (
Syzy
gium
aro
mati
cum
)....5
0 m
g
(flow
er b
ud/ b
ourg
eon
flora
l) (3
0% v
ola�
le o
il/ h
uile
vol
a�le
)
(equ
ival
ent t
o/ é
quiv
alen
t à 1
50 m
g dr
ied
herb
/ de
herb
e sé
chée
)*N
on-m
edic
inal
Ingr
edie
nts/
Ingr
édie
nts N
on-m
édic
inau
x:m
agne
sium
cap
ryla
te/
capr
ylat
e de
mag
nési
um, u
ndec
ylen
ic a
cid/
ac
ide
undé
cylé
niqu
e, s
ilico
n di
oxid
e/ d
ioxy
de d
e sil
iciu
m, L
-Leu
cine
, pu
llula
n/ h
ypro
mel
lose
(cap
sule
)Su
gges
ted
Use
/ U
�lis
a�on
Sug
géré
e:
Adul
ts -
Take
1 ca
psul
e w
ith m
eal,
2-3
�mes
per
day
, or a
s dire
cted
by
your
hea
lth ca
re p
rac�
�one
r. Fo
r pro
long
ed u
se, c
onsu
lt a
heal
th ca
re
prac
��on
er./
Ad
ulte
s -
Pren
dre
1 ca
psul
e av
ec d
es a
limen
ts, 2
-3 f
ois
par
jour
ou
selo
n le
s re
com
man
da�o
ns d
e vo
tre
pra�
cien
de
sant
é. P
our
une
u�lis
a�on
pro
long
ée, c
onsu
ltez u
n pr
ofes
sionn
el d
e la
sant
é.
Cau�
on/
Mis
e en
Gar
de:
Do n
ot u
se i
f yo
u ar
e pr
egna
nt o
r br
eas�
eedi
ng;
or i
f yo
u ha
ve
hype
rsen
si�vi
ty t
o he
rbs
in L
amia
ceae
fam
ily. C
onsu
lt a
heal
th c
are
prac
��on
er i
f sy
mpt
oms
pers
ist o
r w
orse
n. C
onsu
lt a
heal
th c
are
prac
��on
er p
rior
to u
se if
you
hav
e di
abet
es;
or if
you
are
tak
ing
bloo
d th
inne
rs o
r pr
otea
se in
hibi
tors
. Hyp
erse
nsi�
vity
(e.
g. a
llerg
y)
has b
een
know
n to
occ
ur; i
n w
hich
cas
e di
scon
�nue
use
./
Ne
pas
u�lis
er
si vo
us
êtes
en
cein
te.
ou
si vo
us
avez
un
e hy
pers
ensib
ilité
à d
es h
erbe
s dan
s la
fam
ille
des L
amia
cées
. Con
sulte
r un
pra
�cie
n de
soi
ns d
e sa
nté
si le
s sy
mpt
ômes
per
siste
nt o
u s'a
ggra
vent
. Con
sulte
r un
pra�
cien
de
soin
s de
sant
é av
ant d
'en
faire
l'u
sage
si v
ous s
ouffr
ez d
e di
abèt
e ; s
i vou
s pre
nez d
es a
n�co
agul
ants
ou
des
inh
ibite
urs
de p
roté
ase.
Une
hyp
erse
nsib
ilité
(e.
g. u
ne
alle
rgie
) peu
t se
man
ifest
er. S
i tel
est
le c
as, c
esse
r l'u
�lisa
�on.
Stor
e at
ro
om
tem
pera
ture
aw
ay
from
he
at
and
moi
stur
e (<
30o C/
<60%
RH).
Plea
se fi
nish
con
sum
ing
the
prod
uct w
ithin
60
days
a�
er o
peni
ng. D
o no
t us
e if
cap
seal
is b
roke
n. K
eep
out
of r
each
of
child
ren.
/ Con
serv
er à
la te
mpé
ratu
re a
mbi
ante
loin
de
la ch
aleu
r et d
e l’h
umid
ité (
<30o C/
<60%
RH).
S’il
vous
pla
ît te
rmin
er l
e pr
odui
t es
t co
nsom
mé
dans
les 6
0 jo
urs a
près
ouv
ertu
re. N
e pa
s u�l
iser s
i le
scea
u de
sécu
rité
est b
risé
ou m
anqu
ant.
Gard
ez h
ors d
e po
rtée
des
enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.M
aple
Rid
ge, B
.C.,
V2X
8G1,
Can
ada
| w
ww
.vita
aid.
comMicrocidin®
Vegan
Form
ulas
Form
ules
Veg
an
84 Vegetarian Capsules NPN 80034936
Broad-Spectrum Anti-microbial Formula
Helps to relieve the symptoms associated with upper
respiratory tract infections and catarrhal conditions.
À large spectre anti-microbien formule
Pour aider à soulager les symptômes associés à des
infections respiratoires hautes et les conditions
catarrhales.
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
caps
ule)
:
Cop�
s Ext
ract
/ Ext
rait
de C
op�s
(Hua
ng Li
an) (
12:1
).....
......
......
..60
mg
(C
optis
chin
ensis
) (rh
izom
e) (2
0% b
erbe
rine)
(e
quiv
alen
t to/
équ
ival
ent à
720
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
Garli
c/ A
il (A
llium
sativ
um) (
bulb
/ bul
be)..
......
......
......
......
......
..240
mg
(1
0,00
0 m
cg a
llicin
/g) (
20,0
00 m
cg a
lliin
/g)
Oreg
ano
Extr
act/
Ext
rait
d'or
igan
(23
:1) (
Orig
anum
vulg
are)
.....4
0 m
g
(le
af/ f
euill
e) (3
0% ca
rvac
rol)
(e
quiv
alen
t to/
équ
ival
ent à
920
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
*Clo
ve E
xtra
ct/ E
xtra
it de
giro
fle (3
:1) (
Syzy
gium
aro
mati
cum
)....5
0 m
g
(fl
ower
bud
/ bou
rgeo
n flo
ral)
(30%
vol
a�le
oil/
hui
le v
ola�
le)
(e
quiv
alen
t to/
équ
ival
ent à
150
mg
drie
d he
rb/ d
e he
rbe
séch
ée)
*Non
-med
icina
l Ing
redi
ents
/ Ing
rédi
ents
Non
-méd
icina
ux:
mag
nesiu
m c
apry
late
/ ca
pryl
ate
de m
agné
sium
, und
ecyl
enic
acid
/
acid
e un
décy
léni
que,
silic
on d
ioxid
e/ d
ioxy
de d
e sil
icium
, L-L
eucin
e,
pullu
lan/
hyp
rom
ello
se (c
apsu
le)
Sugg
este
d Us
e/ U
�lisa
�on
Sugg
érée
:
Adul
ts -
Take
1 ca
psul
e w
ith m
eal,
2-3
�mes
per
day
, or a
s dire
cted
by
your
hea
lth ca
re p
rac�
�one
r. Fo
r pro
long
ed u
se, c
onsu
lt a h
ealth
care
prac
��on
er./
Adul
tes
- Pre
ndre
1 c
apsu
le a
vec
des
alim
ents
, 2-3
fois
par
jour
ou
selo
n le
s re
com
man
da�o
ns d
e vo
tre
pra�
cien
de s
anté
. Pou
r un
e
u�lis
a�on
pro
long
ée, c
onsu
ltez u
n pr
ofes
sionn
el d
e la
sant
é.
Cau�
on/ M
ise e
n Ga
rde:
Do n
ot u
se i
f yo
u ar
e pr
egna
nt o
r br
eas�
eedi
ng;
or i
f yo
u ha
ve
hype
rsen
si�vi
ty to
her
bs in
Lam
iace
ae fa
mily
. Con
sult
a he
alth
car
e
prac
��on
er if
sym
ptom
s pe
rsist
or
wor
sen.
Con
sult
a he
alth
car
e
prac
��on
er p
rior
to u
se if
you
hav
e di
abet
es; o
r if
you
are
taki
ng
bloo
d th
inne
rs o
r pr
otea
se in
hibi
tors
. Hyp
erse
nsi�
vity
(e.g
. alle
rgy)
has b
een
know
n to
occ
ur; i
n w
hich
case
disc
on�n
ue u
se./
Ne
pas
u�lis
er
si vo
us
êtes
en
cein
te.
ou
si vo
us
avez
un
e
hype
rsen
sibili
té à
des h
erbe
s dan
s la f
amill
e de
s Lam
iacé
es. C
onsu
lter
un p
ra�c
ien
de s
oins
de
sant
é si
les
sym
ptôm
es p
ersis
tent
ou
s'agg
rave
nt. C
onsu
lter u
n pr
a�cie
n de
soin
s de
sant
é av
ant d
'en
faire
l'usa
ge si
vous
souff
rez d
e di
abèt
e ; s
i vou
s pre
nez d
es a
n�co
agul
ants
ou d
es i
nhib
iteur
s de
pro
téas
e. U
ne h
yper
sens
ibili
té (
e.g.
une
alle
rgie
) peu
t se
man
ifest
er. S
i tel
est
le ca
s, ce
sser
l'u�
lisa�
on.
Stor
e at
ro
om
tem
pera
ture
aw
ay
from
he
at
and
moi
stur
e
(<30
o C/<6
0%RH
). Pl
ease
fini
sh c
onsu
min
g th
e pr
oduc
t with
in 6
0 da
ys
a�er
ope
ning
. Do
not u
se if
cap
sea
l is
brok
en. K
eep
out o
f rea
ch o
f
child
ren.
/ Con
serv
er à
la te
mpé
ratu
re am
bian
te lo
in d
e la
chal
eur e
t de
l’hum
idité
(<3
0oC/
<60%
RH).
S’il
vous
pla
ît te
rmin
er l
e pr
odui
t es
t
cons
omm
é da
ns le
s 60
jour
s apr
ès o
uver
ture
. Ne
pas u
�lise
r si le
scea
u
de sé
curit
é es
t bris
é ou
man
quan
t. Ga
rdez
hor
s de
porté
e de
s enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.
Map
le R
idge
, B.C
., V2
X 8G
1, C
anad
a |
ww
w.vi
taai
d.co
m
Microcidin ®
Vega
n Form
ulas
Form
ules V
egan
84 Vegetarian CapsulesNPN 80034936
Dosage Form: 84 Vegetarian Capsules
Broad-Spectrum Anti-Microbial & Anti-Candida Formula
15
Neuromin
Neuromin is a comprehensive formula to support nerve regeneration and prevent cognitive decline. Working via various mechanisms to protect neurons from damage with aging and restore function in various disease processes.
•Pyrroloquinoline quinone (PQQ) facilitates nerve regeneration by promoting nerve growth factor, and also acts as aneuro-protectantviait’santioxidanteffects.Itsbenefitsfor memory & attention are enhanced by the addition of CoQ10 according to clinical data.
•PQQ protects mitochondria by significantly reducing levels of inflammatory markers such as CRP and IL-6.
•Benfotiamine combined with folate and B12 resulted in significant improvement in nerve conduction velocity and is effective in the treatment of diabetic neuropathy.
•Active R-alpha lipoic acid provides additional antioxidant effects and protects nerves and mitochondria from damage.
•Phosphatidylserine has been shown to enhance memory and cognitive function in elderly patients.
• Active forms of vitamin B12 and folate to support methylation process in neurons.
Ingredients (per capsule):Pyrroquinoline quinone (BioPQQ®) ................................................ 5 mgCoenzyme Q10 (ubiquinone) .....................................................37.5 mgR-alpha-lipoic acid (sodium salt) (stabilized) .............................. 75 mgBenfotiamine ............................................................................... 35 mg5-Methyltetrahydrofolate (from Ca 5-MTHF) ............................100 mcgNiacinamide ............................................................................... 25 mgVitaminB2(riboflavin-5’-phosphate(sodiumsalt)) ........................ 5 mgVitaminB6(pyridoxal5’-phosphate) ............................................. 5 mgVitamin B12 (methylcobalamin) ..............................................100 mcgMixed Phospholipids (from Glycine max) ....................................50 mg (seed) (phosphatidylserine, phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine)
Non-medicinal Ingredients: Silicon dioxide, L-Leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 2 capsules, 2 times per day, or as directed by your health care practitioner. Use for a minimum of 3 months to see beneficial effects. For prolonged use over 24 weeks, consult a health care practitioner.
Dosage Form: 56 Vegetarian Capsules
Comprehensive Neuro-Protective Formula
•Allium-free formula (low-FODMAP compatible) for individuals sensitive to garlic.
•Berberine has been shown to improve IBS symptoms (abdominal pain, stool frequency & urgency), as well as anxiety and depression in patients with IBS-D.
•Cinnamon - “warming”`antimicrobial toprevent loose stool fromthe“cooling”propertyofberberine.
•Synergized with concentrated Thyme and Oregano extracts for spasmolytic, carminitive, and broad spectrum antimicrobial effect in the GI tract.
•Neem and Uva Ursi extract are potent antimicrobials, anti-biofilm, and provide additional gastroprotective and antiulcer effects.
Ingredients (per capsule):Berberine Hydrochloride ...........................................................300 mgThyme Extract 20:1 (Thymus vulgaris) .......................................... 35 mg (leaf) (equivalent to 700 mg dried herb)Cinnamon Extract 10:1 (Cinnamomum aromaticum) ...............40 mg (bark) (equivalent to 400 mg dried herb)Neem Extract 20:1 (Azadirachta indica) ..................................... 35 mg (leaf) (equivalent to 700 mg dried herb)Uva Ursi Extract 10:1 (Arctostaphylos uva-ursi) ............................. 35 mg (leaf) (equivalent to 350 mg dried herb)Oregano Extract 5:1 (Origanum vulgare) .................................... 75 mg (leaf) (30% carvacrol) (equivalent to 375 mg dried herb)
Non-medicinal Ingredients: Silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 1 capsule with food, 2-3 times per day, or as directed by a health care practitioner.
Microcidin®AF
Microcidin® AF is a low-FODMAP“Allium-Free” broad spectrum antimicrobial formula that targets multiple mechanisms to inhibit and eradicate pathogenic bacteria, fungi and parasites.
814741
00140
6
Free of Garlic (Allium sativa)Antimicrobial Herbal Formula for Sulfur-SensitiveSupportive treatment of mild to moderate diarrhea.Relief for symptoms of digestive disturbances eg. mild spasm, bloating, and flatulence.
Sans Ail (Allium sativa)Formule herbacée antimicrobienne pour le soufre-sensibleTraitement de la diarrhée légère à modérée. Soulagement pour les symptômes de troubles digestifs, tels que le spasme léger, les ballonnements et les flatulences.
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
cap
sule
):Be
rber
ine
Hydr
ochl
orid
e/ C
hlor
hydr
ate
de b
erbé
rine.
......
......
......
....3
00 m
gTh
yme
Extr
act/
Extr
ait d
e Th
ym (2
0:1)
(Thy
mus
vul
garis
).....
......
......
...35
mg
(le
af/ f
euill
e) (7
00 m
g DH
E*)
Cinn
amon
Ext
ract
/ Ext
rait
de C
anne
lle (1
0:1)
......
......
......
......
......
......
..40
mg
(Ci
nnam
omum
aro
mati
cum
) (ba
rk/é
corc
e) (4
00 m
g DH
E*)
Nee
m E
xtra
ct/ E
xtra
it de
Mar
gous
ier (
20:1
) (Az
adira
chta
indi
ca)..
.....3
5 m
g (
leaf
/feu
ille)
(700
mg
DHE*
)U
va-U
rsi E
xtra
ct/E
xtra
it de
Uva
Urs
i (10
:1)..
......
......
......
......
......
......
....3
5 m
g
(Arc
tost
aphy
los u
va-u
rsi)
(leaf
/feu
ille)
(350
mg
DHE*
)O
rega
no E
xtra
ct/ E
xtra
it d'
orig
an (5
:1) (
Orig
anum
vul
gare
).....
......
.....7
5 m
g (
30%
car
vacr
ol) (
leaf
/ feu
ille)
(375
mg
DHE*
)*D
HE -
drie
d he
rb e
quiv
alen
t/éq
uiva
lent
d'h
erbe
s séc
hées
Non
-med
icin
al In
gred
ient
s/ In
gréd
ient
s Non
-méd
icin
aux:
L-L
euci
ne,
silic
on d
ioxi
de/ d
ioxy
de d
e sil
iciu
m, p
ullu
lan/
hyp
rom
ello
se (c
apsu
le)
Sugg
este
d U
se/
U�l
isa�
on S
uggé
rée:
Ad
ults
- T
ake
1 ca
psul
e w
ith m
eal,
2-3
�mes
per
day
with
foo
d, o
r as
di
rect
ed b
y yo
ur h
ealth
car
e pr
ac��
oner
. Fo
r pr
olon
ged
use,
con
sult
a he
alth
car
e pr
ac��
oner
./
Adul
tes
- Pr
endr
e 1
caps
ule
avec
des
alim
ents
, 2-3
foi
s pa
r jo
ur a
vec
la
nour
ritur
e, o
u se
lon
les
reco
mm
anda
�ons
de
votr
e pr
a�ci
en d
e sa
nté.
Po
ur u
ne u
�lisa
�on
prol
ongé
e, c
onsu
ltez u
n pr
ofes
sionn
el d
e la
sant
é.Ca
u�on
/ M
ise
en G
arde
: Do
not
use
if y
ou a
re p
regn
ant
or b
reas
�eed
ing;
or
if yo
u ar
e tr
ying
to
conc
eive
. Con
sult
a he
alth
care
pra
c��o
ner p
rior t
o us
e if
you
have
dia
bete
s, hy
pogl
ycem
ia, h
ypot
ensio
n. a
kid
ney
diso
rder
, gal
l sto
nes,
a li
ver d
isord
er,
feve
r, pa
infu
l ur
ina�
on,
spas
ms,
or b
lood
in
urin
e; o
r if
you
are
taki
ng
diur
e�cs
or
othe
r pr
escr
ip�o
n m
edic
a�on
s as
ber
berin
e m
ay a
lter
thei
r eff
ec�v
enes
s. Di
scon
�nue
use
and
con
sult
a he
alth
car
e pr
ac��
oner
if
sym
ptom
s w
orse
n or
dia
rrhe
a pe
rsist
s fo
r lo
nger
tha
n 8
days
; if
stoo
l co
ntai
ns b
lood
/muc
ous;
or
if di
arrh
ea i
s ac
com
pane
id b
y a
high
fev
er.
Hype
rsen
si�vi
ty/a
llerg
y m
ay o
ccur
; in
whi
ch c
ase,
disc
on�n
ue u
se./
Ne
pas
u�lis
er s
i vo
us ê
tes
ence
inte
; ou
si
vous
ess
ayez
de
conc
evoi
r. Co
nsul
ter u
n pr
a�ci
en d
e so
ins d
e sa
nté
avan
t d'e
n fa
ire l'
usag
e si
vous
ave
z un
dia
bète
, une
hyp
ogly
cém
ie, u
ne h
ypot
ensio
n, u
n tr
oubl
e du
rei
n, d
es
calc
uls b
iliai
res,
un tr
oubl
e du
foie
, de
la fi
èvre
, des
mic
�ons
dou
lour
euse
s, de
s sp
asm
es, o
u du
san
g da
ns l'
urin
e; o
u si
vous
pre
nez
des
diur
é�qu
es o
u d'
autr
es m
édic
amen
ts su
r ord
onna
nce
parc
e qu
e la
ber
bérin
e pe
ut m
odifi
er
leur
effi
caci
té..
Susp
endr
e l'u
�lisa
�on
et c
onsu
lter
un p
rofe
ssio
nnel
de
la
sant
é si
les s
ympt
ômes
s'ag
grav
ent o
u qu
e la
dia
rrhé
e pe
rsist
e pe
ndan
t plu
s de
8 jo
urs;
si l
es s
elle
s co
n�en
nent
du
sang
ou
des
muq
ueus
es; o
u si
la
diar
rhée
est
acc
ompa
gnée
d'u
ne fi
èvre
sév
ère.
Une
hyp
erse
nsib
i�té
/ al
lerg
ie p
eut s
e m
anife
ster
. Dan
s ce
cas,
cess
er l'
u�lis
a�on
.St
ore
at ro
om te
mpe
ratu
re a
way
from
hea
t and
moi
stur
e (<
30o C/
<60%
RH).
Plea
se fi
nish
con
sum
ing
the
prod
uct w
ithin
60
days
a�e
r ope
ning
. Do
not
use
if ca
p se
al is
bro
ken.
Kee
p ou
t of
rea
ch o
f ch
ildre
n./
Cons
erve
r à
la
tem
péra
ture
am
bian
te lo
in d
e la
chal
eur e
t de
l’hum
idité
(<30
o C/<6
0%RH
). S’
il vo
us p
laît
term
iner
le p
rodu
it es
t co
nsom
mé
dans
les
60 jo
urs
aprè
s ou
vert
ure.
Ne
pas
u�lis
er s
i le
scea
u de
séc
urité
est
bris
é ou
man
quan
t. Ga
rdez
hor
s de
port
ée d
es e
nfan
ts.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.M
aple
Rid
ge, B
.C.,
V2X
8G1,
Can
ada
| w
ww
.vita
aid.
com
Microcidin®AF
Vegan
Form
ulas
Form
ules
Veg
an
84 Vegetarian Capsules NPN 80079467
8
1
4
7
4
1
0
0
1
4
0
6
Free of Garlic (Allium sativa)
Antimicrobial Herbal Formula for Sulfur-Sensitive
Supportive treatment of mild to moderate diarrhea.
Relief for symptoms of digestive disturbances
eg. mild spasm, bloating, and flatulence.
Sans Ail (Allium sativa)
Formule herbacée antimicrobienne pour le soufre-sensible
Traitement de la diarrhée légère à modérée. Soulagement
pour les symptômes de troubles digestifs, tels que le
spasme léger, les ballonnements et les flatulences.
Ingr
edie
nts/
Ingr
édie
nts (
per/
par
caps
ule)
:
Berb
erin
e Hy
droc
hlor
ide/
Chl
orhy
drat
e de
ber
bérin
e....
......
......
......
.300
mg
Thym
e Ex
trac
t/Ex
trai
t de
Thym
(20:
1) (T
hym
us vu
lgar
is)...
......
......
.....3
5 m
g
(le
af/ f
euill
e) (7
00 m
g DH
E*)
Cinn
amon
Ext
ract
/ Ext
rait
de C
anne
lle (1
0:1)
......
......
......
......
......
......
..40
mg
(Ci
nnam
omum
aro
mati
cum
) (ba
rk/é
corc
e) (4
00 m
g DH
E*)
Neem
Ext
ract
/ Ext
rait
de M
argo
usie
r (20
:1) (
Azad
irach
ta in
dica
).....
..35
mg
(le
af/f
euill
e) (7
00 m
g DH
E*)
Uva-
Ursi
Extr
act/
Extr
ait d
e Uv
a Ur
si (1
0:1)
......
......
......
......
......
......
......
35 m
g
(A
rcto
stap
hylo
s uva
-urs
i) (le
af/f
euill
e) (3
50 m
g DH
E*)
Oreg
ano
Extr
act/
Ext
rait
d'or
igan
(5:1
) (Or
igan
um vu
lgar
e)...
......
......
.75
mg
(30
% ca
rvac
rol)
(leaf
/ feu
ille)
(375
mg
DHE*
)
*DHE
- dr
ied
herb
equ
ival
ent/
équi
vale
nt d
'her
bes s
éché
es
Non-
med
icina
l Ing
redi
ents
/ Ing
rédi
ents
Non
-méd
icina
ux: L
-Leu
cine,
silico
n di
oxid
e/ d
ioxy
de d
e sil
icium
, pul
lula
n/ h
ypro
mel
lose
(cap
sule
)
Sugg
este
d Us
e/ U
�lisa
�on
Sugg
érée
:
Adul
ts -
Tak
e 1
caps
ule
with
mea
l, 2-
3 �m
es p
er d
ay w
ith f
ood,
or
as
dire
cted
by
your
hea
lth c
are
prac
��on
er. F
or p
rolo
nged
use
, con
sult
a
heal
th ca
re p
rac�
�one
r./
Adul
tes
- Pre
ndre
1 c
apsu
le a
vec
des
alim
ents
, 2-3
fois
par
jour
ave
c la
nour
ritur
e, o
u se
lon
les
reco
mm
anda
�ons
de
votr
e pr
a�cie
n de
san
té.
Pour
une
u�l
isa�o
n pr
olon
gée,
cons
ulte
z un
prof
essio
nnel
de
la sa
nté.
Cau�
on/ M
ise e
n Ga
rde:
Do n
ot u
se if
you
are
pre
gnan
t or
bre
as�e
edin
g; o
r if
you
are
tryin
g to
conc
eive
. Con
sult
a hea
lth ca
re p
rac�
�one
r prio
r to
use i
f you
hav
e dia
bete
s,
hypo
glyc
emia
, hyp
oten
sion.
a k
idne
y di
sord
er, g
all s
tone
s, a
live
r diso
rder
,
feve
r, pa
infu
l urin
a�on
, sp
asm
s, or
blo
od in
urin
e; o
r if
you
are
takin
g
diur
e�cs
or
othe
r pr
escr
ip�o
n m
edica
�ons
as
berb
erin
e m
ay a
lter
thei
r
effec
�ven
ess.
Disc
on�n
ue u
se a
nd c
onsu
lt a
heal
th c
are
prac
��on
er i
f
sym
ptom
s w
orse
n or
dia
rrhe
a pe
rsist
s fo
r lo
nger
tha
n 8
days
; if
stoo
l
cont
ains
blo
od/m
ucou
s; or
if
diar
rhea
is
acco
mpa
neid
by
a hi
gh f
ever
.
Hype
rsen
si�vit
y/al
lerg
y may
occ
ur; i
n w
hich
case
, disc
on�n
ue u
se./
Ne p
as u
�lise
r si
vous
ête
s en
cein
te;
ou s
i vou
s es
saye
z de
con
cevo
ir.
Cons
ulte
r un
pra�
cien
de so
ins d
e sa
nté
avan
t d'e
n fa
ire l'u
sage
si vo
us a
vez
un d
iabè
te, u
ne h
ypog
lycém
ie, u
ne h
ypot
ensio
n, u
n tro
uble
du
rein
, des
calcu
ls bi
liaire
s, un
trou
ble
du fo
ie,
de la
fièv
re, d
es m
ic�on
s dou
lour
euse
s,
des s
pasm
es, o
u du
sang
dan
s l'u
rine;
ou
si vo
us p
rene
z des
diu
ré�q
ues o
u
d'au
tres m
édica
men
ts su
r ord
onna
nce
parc
e qu
e la
ber
bérin
e pe
ut m
odifi
er
leur
effi
cacit
é.. S
uspe
ndre
l'u�
lisa�
on e
t co
nsul
ter
un p
rofe
ssio
nnel
de
la
sant
é si
les s
ympt
ômes
s'ag
grav
ent o
u qu
e la
dia
rrhé
e pe
rsist
e pe
ndan
t plu
s
de 8
jour
s; si
les
selle
s co
n�en
nent
du
sang
ou
des
muq
ueus
es; o
u si
la
diar
rhée
est
acc
ompa
gnée
d'u
ne fi
èvre
sév
ère.
Une
hyp
erse
nsib
i�té
/
alle
rgie
peu
t se
man
ifest
er. D
ans c
e ca
s, ce
sser
l'u�l
isa�o
n.
Stor
e at
room
tem
pera
ture
away
from
hea
t and
moi
stur
e (<
30oC/
<60%
RH).
Plea
se fi
nish
con
sum
ing
the
prod
uct w
ithin
60
days
a�e
r ope
ning
. Do
not
use
if ca
p se
al is
bro
ken.
Kee
p ou
t of
rea
ch o
f chi
ldre
n./
Cons
erve
r à
la
tem
péra
ture
am
bian
te lo
in d
e la
chal
eur e
t de
l’hum
idité
(<30
oC/
<60%
RH).
S’il
vous
pla
ît te
rmin
er le
pro
duit
est c
onso
mm
é da
ns le
s 60
jour
s ap
rès
ouve
rtur
e. N
e pa
s u�
liser
si l
e sc
eau
de s
écur
ité e
st b
risé
ou m
anqu
ant.
Gard
ez h
ors d
e po
rtée
des
enf
ants
.
Man
ufac
ture
d by
/ Fab
riqué
par
: Nat
uro
Aid
Phar
mac
eu�c
al In
c.
Map
le R
idge
, B.C
., V2
X 8G
1, C
anad
a |
ww
w.vi
taai
d.co
m
Microcidin® AF Vegan Fo
rmula
s
Form
ules
Vegan
84 Vegetarian CapsulesNPN 80079467
Dosage Form: 84 Vegetarian Capsules
Low FODMAP Anti-Microbial Formula
VII
16
• Acts on the 5-HT receptors to promote gastrointestinal migrating motor complex (MMC) function.
• Promotes digestive enzyme & bile secretions.
• Contains cofactors to support neurotransmitter synthesis & restore MMC.
• Indications:
- Small intestine bacterial overgrowth (SIBO)
- Dyspepsia, Gastroparesis, Indigestion, Nausea & Vomiting
- Gastroesophageal Reflux Disease (GERD)
- Irritable Bowel Syndrome (IBS)
Ingredients (per 3 capsules):L-5-HTP (L-5-Hydroxytryptophan) ................................................ 225 mg (from Griffonia simplicifolia) (seed)Ginger Extract (Zingiber officinalis) ............................................600 mg (rhizome) (standardized to contain 6% gingerols)Chamomile Extract 10:1 (Maticaria chamomilla) .................... 150 mg (flower) (equivalent to 1500 mg of dried herb)Cinnamon Extract 10:1 (Cinnamomum aromticum) ..................90 mg (bark) (equivalent to 900 mg of dried herb)Peppermint Extract 20:1 (Mentha x piperita) ............................. 120 mg (herb) (equivalent to 2400 mg of dried herb)Gentian Extract 10:1 (Gentiana lutea) .........................................90 mg (root) (equivalent to 900 mg of dried herb)Benfotiamine ...............................................................................30 mgVitamin B6 (from calcium pyridoxal-5-phosphate) ..................... 15 mg5-Methyltetrahydrofolate (from Ca 5-MTHF) ............................300 mcgVItamin B12 (methylcobalamin) ..............................................300 mcg
Non-medicinal Ingredients: Silicon dioxide, L-leucine, pullulan/hypromellose (capsule)
Suggested Use: Adults - Take 1 capsule between lunch and dinner, and 2 capsules at bed time, on an empty stomach; or as directed by a health care practitioner.
Prokine
Dosage Form: 126 Vegetarian Capsules
Natural Prokinetic FormulaComprehensive Prokinetic Formula to help regulate gut motility.
Resolaxin is a comprehensive herbal stress management formula targeting individuals that are constantly stressed, nervous, anxious, restless, and/or suffering from Irritable Bowel Syndrome (IBS).
•Natural herbal combination that works by binding the GABA receptors to promote muscle relaxation and calm the mind.
•Wild jujube seed is a traditional Chinese medicine herb used for calming the mind, improving sleep quality & digestive function, and reducing the high blood pressure & relieving IBS caused by stress.
•Contains L-theanine to induce a sense of inner calm without affecting alertness.
•Combination of carminative and calming herbs - an ideal formulation for IBS.
Resolaxin
Ingredients (per 2 capsules):(Contains 6360 mg Dried Herb Equivalent) Chamomile Extract 6:1 (Matricaria chamomilla) ..................... 240 mg (flower) (1% apigenin) (equivalent to 1440 mg dried herb)Lemon Balm Extract 5:1 (Melissa officinalis) .............................. 120 mg (leaf) (5% rosmarinic acid) (equivalent to 600 mg dried herb)Wild Jujube Extract 18:1 (Zizyphus spinosa) ............................... 220 mg (seed) (2% triterpene saponins) (equivalent to 3960 mg dried herb)Passion Flower Extract 4:1 (Passiflora incarnata) .........................90 mg (flower) (3.5% vitexin) (equivalent to 360 mg dried herb)L-Theanine (from Camellia sinensis) (leaf) ...................................80 mgMagnesium (from magnesium citrate) .......................................50 mgVitamin B6 (from pyridoxine hydrochloride) ................................ 10 mg
Non-medicinal Ingredients: Silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Adults - Take 2 capsules 2-3 times a day, or as needed for calming effect. Take 2-3 capsules 1/2 to 1 hour before sleep as needed for relaxation and better sleep. Take 1-2 capsules with each meal for IBS. Or else use as directed by a health care practitioner.
Eases stress and promotes relaxation without sedative effects
Dosage Form: 56 / 112 Vegetarian Capsules
17
Saccharomyces boulardii is a probiotic clinically used in the treatment and prevention of gastrointestinal disease such as antibiotic-associated diarrhea, acute traveller’s diarrhea, C. difficile infections, and H. pylori.
•The most effective probiotic for the prevention and treatment of antibiotic-associated diarrhea and recurrent C. difficile infections.
•Significantly reduces the duration of acute childhood diarrhea and the risk of prolonged diarrhea.
•Improves intestinal permeability and reduces relapse rate in patientswithCrohn’sdisease.
•Reduces diarrhea in patients undergoing total enteral nutrition (TEN).
•Regulates intestinal microbial homeostasis and stabilizes the gastrointestinal barrier, interfering with the ability of pathogens to colonize and infect the mucosa.
•Modulates local and systemic immune responses.
Ingredients (per capsule):Saccharomyces boulardii (whole cell)................................ 5 billion cfu
*cfu - colony forming units
Non-medicinal Ingredients: L-leucine, maltodextrin, silicon dioxide, hypromellose/ pullulan (capsule)
Suggested Use: Children, Adolescents, and Adults – Take 2 capsules, 1-3 times aday, or as directed by a health care practitioner. For children under 6 years old, open the capsule and administer the powder form.
S. boulardii
Dosage Form: 84 Vegetarian Capsules
Clinical Manifestations• Liver blood deficiency with deficiency-heat (yin-deficiency)
rising further leading to Heart yin & blood deficiency. Signs & Symptoms: irritability, insomnia, palpitations, night sweating, dizziness, vertigo, dry mouth and throat.
• Tongue Appearance: dry, red tongue
• Pulse Pattern: a thready, wiry pulse, maybe rapid.
Formula RationaleSerenomind (Suan Zao Ren Wan) is designed primarily to treat insomnia caused by Liver blood deficiency with deficiency heat risingduetochronicoverexertion–bothphysically&mentally.
The primary strategy is to nourish the Heart and calm the spirit; heat-clearing is the secondary strategy.
Thechiefherb–Suan Zao Ren (WildJujubeSeed)–nourishesthe Heart and Liver and calms the spirit.
Thedeputy herb –Chuan Xiong – regulates Liverblood flow.This combination of blood astringing and dispersing herbs is very effective in cases of Liver blood deficiency resulting in deficiency heat rising.
The assistant herbs are Fu Ling, which calms the spirit and tonifies the Spleen and Stomach, and Zhi Mu, which nourishes Yin,clearsheat,andmoistens internaldryness (controlling thedrying properties of Chuan Xiong). Gan Cao (Licorice) – thecarrier–harmonizesallotherherbsintheformula.
SerenomindWild Jujube ComplexSuan Zao Ren Wan / 酸棗仁丸
Nourish the Blood & Calm the Spirit
Ingredients (per capsule):SuanZaoRenWanExtract8:1……………………….......…..………500mg (equivalent to 4.0 g of dried crude ingredients) Contains: Suan Zao Ren (Ziziphus jujube) (seed)...............................208.4 mg Fu Ling (Wolfiporia extensa) (seed)......................................83.3 mg Zhi Mu (Anemarrhena asphodeloides) (root)......................83.3mg Chuan Xiong (Ligusticum sinense) (root)............................83.3 mg Gan Cao (Glycyrrhiza uralensis) (root).................................41.6 mg
Non-medicinal Ingredients: Certified organic apple fiber, pullulan/hypromellose (capsule)
Suggested Use: Adults - Take 3 capsules, 3 times a day, or as directed by a health care practitioner.
Dosage Form: 126 Vegetarian Capsules
VII
18
Verlusan+ is a unique formula with enhanced bioavailability by the addition of Bioperine® (piperine from black pepper). It contains multiple, natural COX-2 inhibiting agents specialized for relief of inflammation, swelling and minor pain.
•Contains daily dosage of 1000 mg of patent iso-alpha acid standardized Humulus lupulus extract clinically proven to be a COX-2 (Cyclyoxygenases) inhibitor with comparable effect to 400 mg ibuprofen.
•Reduces PGE2 production of the specific target cells. Provides effective anti-inflammatory support without the cardiovascular, gastrointestinal and renal adverse effects.
•Containshighlyconcentratedphyto–antioxidantstoscavengefree radicals and reduce oxidative stress in inflamed tissues such as arthritis, muscle tearing, and any discomfort caused by inflammation.
Verlusan+
VA-116
Dosage Form: 84 Vegetarian Capsules
Natural COX-2 inhibitor to relieve inflammation; Bioavailability enhanced by Bioperine®
Ingredients (per capsule):(Each capsule contains 6300 mg Dried Herb Equivalent)Hops Extract 30:1 (Humulus lupulus) .......................................... 167 mg (Perluxan™) (cone) (30% alpha and iso-alpha acids) (equivalent to 5000 mg of dried herb)Boswellia Extract 20:1 (Boswellia serrata) (gum resin) ..................60 mg (65% boswellic acid) (equivalent to 1200 mg of dried herb)Curcumin (from Curcuma longa) .............................................200 mg (root, rhizome) (C3-Complex®)Rosemary Extract 6:1 (Rosmarinus officinalis) ............................. 15 mg (leaf) (equivalent to 90 mg of dried herb)
C3-Complex®and Bioperine®are registered trademarks of Sabinsa Corp.
Non-medicinal Ingredients: L-leucine, pullulan/hypromellose (capsule), piperine (Bioperine®)
Suggested Use: Adults - Take 3 capsules, 2 times a day, or as directed by a health care practitioner.
Supreme-PB30+ DF is a Dairy Free probiotic formula that contains 55 billion viable cells comprised of 11 species of human gut-anchoring probiotics to ensure successful establishment in each of their particular niche.
•Carefully selected strains with complete resistance tests (22 antibiotics); all genomes are ATCC-registered.
•All strains are acid- and bile-resistant, ensuring their passage through the entire GI tract while helping inhibit H. pylori infections and C. difficile overgrowth.
•Lactobacillus rhamnosus GG, the most effective probiotic in reducing both severity and duration of acute infectious diarrhea.
•Bifidobacterium lactis Bl-04 is shown in RCT to significantly reduce the risk of upper respiratory infections by 27%.
•Perinatal & neonatal supplementation of L. rhamnosus HN001 has been shown clinically to reduce the risk of gestational diabetes by 68%, as well as eczema (44%) and rhinoconjunctivits (62%) in babies and toddlers.
•Provides formulas with or without prebiotic (FOS) to meet each individual’sneeds.
Ingredients (per capsule):Lactobacillus acidophilus La-14 .......................................... 6 billion cfuLactobacillus rhamnosus Lr-32 ............................................ 2 billion cfuLactobacillus casei Lc-11 .................................................... 5 billion cfuLactobacillus salivarius Ls-33 ............................................... 1 billion cfuBifidobacterium bifidum Bb-06 ........................................... 1 billion cfuBifidobacterium lactis Bl-04 ................................................ 5 billion cfuStreptococcus thermophilus St-21 ...................................... 2 billion cfuBifidobacterium breve Bb-03 ........................................... 1.5 billion cfuLactobacillus plantarum Lp-115 ....................................... 1.5 billion cfuLactobacillus rhamnosus HN001 ........................................ 2 billion cfuLactobacillus rhamnosus GG.............................................. 3 billion cfu
May contain up to 55 billion viable cells at the time of manufacture.
Non-medicinal Ingredients: Fructo-Oligosaccharide (FOS) / maltodextrin, silicon dioxide, L-leucine, pullulan/ hypromellose (capsule)
Suggested Use: Children, Adolescents, Adults - To help manage acute infectious diarrhea, take 1 capsule, 3 times a day; to help reduce the risk of antibiotic-associated diarrhea, take 2 capsules, 2-3 times a day; or use as directed by a health care practitioner. Take at least 2-3 hours before or after antibiotics. For children under 6 years old, open the capsule and administer the powder form.
Supreme-PB30+ DF
Dosage Form: 56 Vegetarian Capsules
19
Vita Aid Professional TherapeuticsToll-Free: 1.800.490.1738 (Canada & US)Phone: 604.465.1688 | Fax: 604.465.1299 | www.vitaaid.com
Eradicate(6 Weeks)
Recovery(6 Months)
Remission(Follow up every 3 month)
Small Intestine Bacterial Overgrowth
1
2
3
Treatment Overview
Fortough-to-eradicatecases (ie. no symptom improvement during and/or after the anti-microbial treatments):BiofilmX - 1 cap, 15-30 min. before meal, TID, for 6 weeks
SIBO Screening Medical History + SIBO Checklist
Lactulose SIBO Breath Test
IfPOSITIVE,starttreatment.
Option#1:Microcidin® – 1 cap TID CC
Alliimin DR - 1 cap TID CC
RepairingGI-Restore®LF– 1 cap TID
Diet
Avoid foods in highest FODMAP category, with the help of Intolerase – take1capCC,BID-TID
Prokinetic
Prokine – 1 cap between lunch & dinner, and 2 caps at bedtime
1)LowCarb&LowFODMAPDiet* *Protein: 30%; Carb: 30%; Fats (avocado, olive, coconut oils): 40%2)Supreme-PB30+DF(withoutFOS)(Probiotics)– 1 cap BID3)BetaineHCl(ifpatienthashypochlorhydria)– take 2 caps CC TID
Followup&Re-assess@3rd,6th,and9thmonths
Option#2:Microcidin®AF* – 1-2 caps TID for 6 weeks*For garlic sensitive, H2-dominant patients
If Symptoms Relapse
Livercleansetominimizedie-offreaction (1-2 weeks prior to and continue through Eradication Phase)
Hepasylin - 2 caps QD.
SymptomRemitted?
YESNO
(Optional) Re-do SIBO Breath Test
Negative
Positive
Consider other co-existing conditions (whilecontinuingtoRecoveryPhase), such as: yeast overgrowth (SIFO), endometriosis, peritoneal space-occupying lesions
Hypochlorhydria
Betaine HCL – 2 caps CC TID
