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    shineSUMMER 2008

    Progress, Patients and Philanthropyat Texas Childrens Hospital

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    MESSAGE FROM THE PRESIDENT AND CEO

    A circleone of natures simplest forms. No shape better represents

    life. We at Texas Childrens Hospital embrace the circle as an

    inspiration for a unique project dedicated to bringing new life into

    the world and to ensuring the health and well being of future

    families in our community and beyond.Earlier this year, we broke ground on Texas Childrens Maternity

    Center and thus began our journey to unite world-class obstetrics,

    gynecology and maternal/fetal medicine services with our already

    outstanding neonatal program and comprehensive array of

    pediatric subspecialty servicesall in one centralized location.

    By linking our pediatric mission with our neonatal and

    maternal fetal medicine vision and extending the services we already

    offer, we are creating a new paradigm for what tomorrows childrenshospitals will look like.

    Texas Childrens Maternity Center will provide an unparalleled

    continuum of pediatric and womens services, a complete circle of

    care to meet the growing and changing needs of families in our

    community.

    Texas Childrens Maternity Center will have the Baylor College

    of Medicine full-time faculty in obstetrics and gynecology,

    including the maternal/fetal medicine experts like those at Texas

    Child F l C h f i f h

    By linking our

    pediatric mission

    with our neonatal

    and maternal fetal

    medicine vision

    d di h

    OFFICERS

    MAX P. WATSON

    CHAIRMAN OF THE BOARD

    BRAD TUCKER

    PRESIDENT

    KEVIN C. KING

    VICE PRESIDENT

    ANN LENTS

    VICE PRESIDENT

    ANTHONY G. PETRELLO

    VICE PRESIDENT

    RONALD C. HULME

    TREASURER & ASSISTANT SECRETARY

    Y. PING SUN

    SECRETARY

    DACE REINHOLDS

    ASSISTANT SECRETARY

    [NON TRUSTEE]

    EMERITUS TRUSTEES

    JOSEPHINE E. ABERCROMBIE

    ALFRED C. GLASSELL, JR.

    ADVISORY BOARD

    EDUARDO AGUIRRE, JR.

    KIRBY ATTWELL

    BEN A. BROLLIER

    GEORGE H. JEWELL

    R. BRUCE LABOON

    VIRGINIA MCFARLAND

    DARRELL C. MORROW

    PHILIP R. NEUHAUS

    MACONDA BROWN OCONNOR, PH.D.

    LOIS F. STARK

    PHOEBE C. WELSH

    ASSOCIATE BOARD

    TOM BACON

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    PROGRESS, PATIENTS AND PHILANTHROPY AT TEXAS CHILDRENS HOSPITAL

    Texas Childrens Hospitalis dedicated to providing the finest

    possible pediatric patient care,education and research.

    SUMMER 2008

    shine

    EDITOR

    AMBER LEWIS TABORA

    CONTRIBUTORS

    ANGELA DOLDER

    DAWN DORSEY

    ERIKA DURHAM HARGROVE

    KATHY ISDALE

    TRAVIS MCCLAIN

    SHANNON RASP

    ANN SAYE

    HEATHER MCLEAN WIEDERHOEFT

    PHOTOGRAPHERS

    PAUL VINCENT KUNTZ

    Nowonlineat

    www.shine.texaschildrens.org

    4FAITH & FETAL MEDICINEPioneering fetal procedure removes rare tumor,gives mother and baby hope

    8TWIN TRIUMPH

    Twin to twin transfusion patientsdepend on fetal intervention for survival

    12THE WAY HOME

    Team-based developmental care helps ensure

    b li f lif f hi h i k i f

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    @ Texas Childrens

    F O R M O R E N E W S , V I S I T U S O N L I N E TEXAS CHILDRENS HOSPITAL | 32 | TEXAS CHILDRENS HOSPITAL

    HO SPIT AL NEWS AND EV ENT S | SU M M ER 2 0 0 8

    Donors, community leaders, area families and Texas Childrens Hospital

    Board of Trustees members gathered May 15 to celebrate the ground-

    breaking of Texas Childrens Hospital West Campus. The first phase,

    scheduled to open in the spring of 2010, will include a 190,000-square-

    foot outpatient clinic with physician offices, and the second phase,

    opening in the fall of 2010, will feature a 280,000-square-foot inpatient

    facility with 48 intermediate and acute care patient beds, surgical suites,

    advanced imaging and diagnostic services and the only dedicated

    pediatric emergency room in the greater West Houston area. Eventually, Texas Childrens Hospital West Campus will be one of the

    countrys largest suburban pediatric hospitals, with up to 500,000 square feet and 96 licensed beds.

    Located in the midst of one of the nations fastest growing areas, the West Campus will serve children and families from Sugar Land

    all the way up to Bryan-College Station. Since 2000, this pediatric population has been growing rapidly and is expected to have increased

    51 percent by 2015.

    Our new West Campus will provide families greater access to the same unsurpassed standard of care for which Texas Childrens

    Hospital is internationally recognized, said Mark A. Wallace, president and chief executive officer of Texas Childrens. It will be a

    premier pediatric treatment facility and a leading community resource center for child wellness and healing.

    At the groundbreaking ceremony, Wallace announced a $3 million gift from ConocoPhillips to the West Campus and to the Jan and

    Dan Duncan Neurological Research Institute. He also thanked Mary and David Wolff, who donated 10 acres of the site on which the

    hospital will be built, a gift valued at $4.5 million.

    Breaking new ground in West Houston

    With the construction of its new Maternity Center underway, Texas Childrens Hospital has acquired theWomens Specialists of Houston (WSH), a private physicians group practicing obstetrics and gynecolo-

    gy, to help care for the women and families the new center will serve.

    We founded the Womens Specialists of Houston to help all people, and the new Maternity Center

    is a manifestation of that vision, said Edward Yosowitz, M.D., managing partner and founder of WSH.

    The group handles 34-40 percent of the deliveries in the Texas Medical Center. By merging with

    Texas Childrens, the groups seven physicians and four nurse midwives will have resources to expand,

    adding at least five more staff physicians over the next five years and helping recruit additional private

    physicians to office in the new Maternity Center facility after completion in 2011.

    Were very excited about the Maternity Cente rits never been done before, added Yosowitz. For patients to have their babies and have

    pediatric services right there, to have research and collaboration with an institution like Baylor right there, its a model that just makes sense.

    Texas Childrens Maternity Centeracquires Womens Specialists of Houston

    For the ninth consecutive year, Texas Childrens has been ranked among the countrys top 10

    foremost pediatric health care facilities in U.S. News & World Reports annual Americas Best

    Childrens Hospitals publication.

    This year, Texas Childrens maintained its No. 6 national ranking and No. 1 ranking in

    this part of the country. In addition, the hospitals overall score and reputation perception reached

    new levels.

    We are excited about this ranking, which is a tribute to the hard work and commitment

    of all our employees and physicians. As we move toward the expansion and 2010, we expect to

    continue to blaze trails at the forefront of pediatric health care, said Mark A.Wallace, Texas

    Childrens president and chief executive officer.

    Texas Childrens did exceptionally well in the pediatric subspecialty categories, placing in

    the top 10 of each category, including No. 2 for respiratory disorders, No. 3 for cancer and for

    cardiology/heart surgery, No. 4 for digestive disorders and No. 5 for neurology/neurosurgery.

    Once again ranked among the nations best

    @ Texas Childrens

    Physician-in-chief announces search for his successor

    A T W W W . T E X A S C H I L D R E N S . O R G

    Ralph D. Feigin, M.D., physician-in-chief of Texas Childrens Hospital and chair

    of the department of pediatrics at Baylor College of Medicine, recently announced

    his intentions to step down from his leadership roles and is helping Texas

    Childrens and Baylor conduct the formal, national search for his successor.

    For more than 30 years, Dr. Feigin has provided extraordinary leadership for

    our institutions, said Mark A. Wallace, president and chief executive officer of

    Texas Childrens Hospital. He has cared for thousands of young patients, trained

    hundreds of residents and medical students and led groundbreaking research.

    Under his leadership, Texas Childrens Hospital and Baylors department of

    pediatrics have grown to international prominence, and he will continue to be an

    invaluable resource to both of our institutions.

    Feigin will continue to serve as physician-in-chief and chair of pediatrics until

    a successor is named and, at that time, continue to serve as a professor ofpediatrics at Baylor and a pediatrician at Texas Childrens.

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    ElijahGraffwithmother,Cynthia

    To the casual observer, it may not look like a miracleKeri

    McCartney cradling her 1-month-old daughter, Macie Hope.

    Making her debut in the world, Macie doesnt realize that hers

    is one of the most miraculous births ever to happen at Texas

    Childrens Hospital. Nor does she know that she had mademedical history even before she was born.

    After all shes been through, shes just at peace now,

    said McCartney. Indeed, Macie is content to doze quietly in her

    mothers arms, blissfully unaware of the herculean effort of faith

    and fetal medicine that it took to bring her into the world a

    healthy girl.

    Its a miracle from God that she is here with usGod

    and Texas Childrens Hospital, added McCartney.

    Holding onto hope

    Macies extraordinary medical odyssey began rather

    mundanely with a routine ultrasound at 23 weeks gestation. We

    had hoped to determine the sex of the baby, explained

    McCartney. My husband, Chad, and I had brought along our

    four children to hear the news.

    But the ultrasound revealed that their babya girlwasnt

    alone in the womb. A tumor, nearly the size of the baby, had

    mushroomed from her tailbone. Macie Hope, they would call her,

    would likely die inside her mother.

    Faced with this dismal future, Hope was all we had,

    said McCartney.

    That hope brought them to Texas Childrens Fetal Center at

    Texas Childrens Hospital, one of only a handful of centers in the

    United Statesand the only center in the Southwestto offer thefull spectrum of fetal therapies including fetal surgery, fetal

    diagnosis and minimally-invasive fetal intervention.

    By the time the McCartneys made the trip from their home

    in Laredo to the Fetal Center, Macies health was already fading.

    Macie had whats known as a sacrococcygeal teratoma, a rare

    tumor that forms at the base of the coccyx. It occurs in about 1 in

    35,000 births, said Darrell Cass, M.D., co-director of the Fetal

    Center and associate professor of pediatric surgery at Baylor

    College of Medicine.

    A fetal echocardiogram to study her heart, a level two

    ultrasound and an MRI were done to help evaluate Macies

    condition and determine the next course of action.

    Tests revealed the monstrous growth was rich with blood

    vessels and thieving blood, causing Macies heart to beat

    frantically. As the tumor grew, she continued to struggle.

    Macies heart was in the process of failing, said Nancy

    Ayres, M.D., director of the echocardiography laboratory at Texas

    Childrens Hospital and fetal cardiology at Texas Childrens Fetal

    Center. She didnt have much time.

    faith&fetal medicine

    A pioneering procedure at Texas Childrens gives

    the McCartney family hope for their daughters life

    By Angela Dolder

    www.t exa sch ild rens .or g TEX AS CHIL DRE NS HOS PITAL | 5Macie McCartney

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    www.t exa sch ild rens .or g TEX AS CHIL DRE NS HOS PITAL | 7

    The Fetal Center treat-

    ment teamincluding Cass

    and co-director Oluyinka

    Olutoye, M.D., maternal-

    fetal medicine specialists

    Anthony Johnson, D.O., and

    Kenneth Moise, M.D., as

    well as neonatologists, obste-

    tricians, fetal cardiologists,

    anesthesiologists and other

    expertsconvened and pre-

    sented the McCartneys withtheir options. They could let

    nature take its deadly course;

    or the team could remove the

    tumor during a daring open

    fetal surgery that would make

    medical history in the

    process. Fewer than 15 of this

    type of procedure had ever

    been done before, according

    to Cass. Fewer still produced positive outcomes.

    While Texas Childrens Fetal Center had performed open fetal

    surgery for fetal lung masses, Macies procedure would be the first

    open fetal surgery for a sacrococcygeal teratoma at Texas Childrens

    Hospitaland it would be Macies only hope for life.We were hoping to do everything we could to save Macie,

    said McCartney. We surrendered Macies fate to our faith and

    chose the surgery.

    Making medical history

    Two weeks after the diagnosis, McCartney, 25 weeks

    pregnant, lay prepped for surgery in a Texas Childrens Hospital

    operating room, ready to risk her own health to save Macie.

    With such a proce-

    dure, Keri was at risk for

    bleeding and early labor,

    said Richard Todd Ivey,

    M.D., assistant professor of

    obstetrics and gynecology at

    Baylor College of Medicine

    and McCartneys ob/gyn at

    Texas Childrens Hospital.

    Even after viewing

    photos of the surgery,

    McCartney still cannot fath-om what the Texas Childrens

    Fetal Center team did next.

    With McCartney

    under many times the

    standard dose of anesthesia,

    surgeons sliced a wide arc

    across her lower abdomen,

    reached inside with gloved

    hands, plucked the uterus

    from her depths and laid it atop her torso. Ivey and Moise

    massaged the uterus in order to properly position Macie for the

    surgery; Ayres monitored Macies heart.

    Lead surgeon Cass made a seven-inch incision into the

    uterine wall, lifted Macies lower half into the world and resectedthe parasitic growth.

    The teratoma was about the size of a grapefruit, said

    co-surgeon Olutoye, associate professor of pediatric surgery at

    Baylor College of Medicine.

    Then Macie was returned to the life-sustaining pool of

    amniotic fluid in the confines of her mothers womb. The uterus

    was reinserted into McCartneys abdomen and the maternal

    flesh sewn closed.

    There, in the secret place,

    breached only by a gifted few,

    Macie remained to strengthen

    herself for life outside the

    womb. Our hope was to

    allow my pregnancy to

    progress to 28 weeks so that

    Macie could develop, said

    McCartney. 30 weeks would

    have been great; 32 weeks

    would have miraculous.

    Macie had other plans.She stayed put for an

    astonishing 10 weeks post-

    surgery until she was born, at

    35 weeks, via cesarean section

    on May 7, said Ivey.

    Macie spent a month in

    the neonatal intensive care unit

    at Texas Childrens Newborn

    Center and later underwent a

    second surgery to remove some internal cysts spawned by the tumor.

    Meanwhile, McCartney recovered nearby at St. Lukes Episcopal

    Hospital Labor and Delivery Unit staffed by Texas Childrens.

    Macies successful surgery is just one more example of the kind

    of expertise that has solidified Texas Childrens Hospital among the eliteinstitutions capable of saving babies before they are born said Cass.

    This is the first of many firsts for the Fetal Center, he added.

    Particularly now, with Texas Childrens Maternity Center on the

    horizon, the future of fetal medicine here is bright.

    Building life

    For families like the McCartneys, Texas Childrens Hospital

    is creating a comprehensive maternity center where world-class

    experts will provide care

    to mothers and babies at

    every stage of pregnancy,

    birth and infancy.

    Slated to open in

    2011, the new Texas

    Childrens Maternity Center

    will galvanize top talent from

    Texas Childrens Fetal

    Center, Texas Childrens

    Newborn Center, obstetrics,

    maternal-fetal medicine andrelated specialtiesultimately

    at one location.

    Our ability to ensure

    comprehensive, multidisci-

    plinary care under the

    auspices of Texas Childrens

    Maternity Center will give

    high-risk patients like Keri

    and Macie the best hope

    for life, explained Ivey. Macie is the perfect example of

    what modern medicine is capable of when the circle of care

    is complete.

    For the McCartneys, hope came full circle in June when they

    headed home to Laredo as a whole familywith a perfectlyhealthy Macie in tow. The only visible evidence of the harrowing

    circumstances surrounding Macies start in life is hidden beneath

    a preemie-sized diaper.

    If God had not brought us to Texas Childrens, our little

    girl would not be here today said McCartney. I am grateful

    that Texas Childrens is building a place like the Maternity

    Center, but really what they are building is life for more

    babies like Macie.

    Above Left: An MRI shows Maciessacroco ccygeal teratoma at 24 weeks.

    Above Right: Chad, Keri, and theirdaughter, Macie McCartney

    Right: The Fetal Center treatment team,co-directors Drs. Darrell Cass and

    Oluyinka Olutoye, and maternal-fetalmedicine specialists Drs. Kenneth

    Moise and Anthony Johnson

    Macie is the perfect example of what

    modern medicineis capableof when the circle of care is complete.- Dr. Richard Todd Ivey, ob/gyn at Texas Childrens

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    www.t exa sch ild rens .or g TEX AS CHI LDR ENS HOS PITAL | 9

    TWINTRIUMPHMother and her twins rely on Texas Childrens

    fetal intervention team for support and survival

    Anayele Martinez knew her stomach would get big, maybe even huge. After all, she was having twins.

    She figured a protruding stomach and backaches came standard with morning sickness and swollen

    ankles. But by her 24th week of pregnancy, big just wasnt the word to describe her.

    My belly was sticking out so far, and the skin on my stomach was pulled so tight it felt like it was going

    to pop, the first-tim e mother recalled. On top o f that, my back hurt terrib ly. Everyone kept telling me it was

    normal, but I knew it wasnt. I knew something had to be wrong.

    During her next check-up at Ben Taub General Hospital, Martinez explained her pains to her resident

    doctor, who had a hunch what the problem might be. Kenneth Moise, M.D., member of the fetal

    intervention team at Texas Childrens Hospital, was immediately called in and the diagnosis was

    confirmedtwin to twin transfusion syndrome (TTTS).

    BY ERIKA E. HARGROVE

    Anayele with Christopher and Jonathan Martinez

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    www.t exa sch ild rens .or g TEX AS CHI LDR ENS HOS PITAL | 11

    TTTS is a condition where the babies share one placenta as

    opposed to each having their own. This placenta contains blood

    vessel connections between the twins that are not balancedblood

    moves one way but does not return. In TTTS, the smaller twin

    (donor twin) sends blood to the larger twin (recipient twin) who

    becomes overloaded.

    In an attempt to reduce its blood volume, the recipient twin

    increases the urine it makes, which eventually results in the twin

    having a very large bladder and too much amniotic fluid. This

    causes a quick increase in the size of the uterus, which is often the

    first sign of trouble that many mothers, including Martinez,

    notice. As the disease progresses, the donor twin makes less and

    less urine so its amniotic fluid disappears and it becomes wrapped

    by its amniotic membrane (known as a stuck twin).

    According to Moise, the condition is extremely severe and

    can be fatal for one or both babies.

    But Martinez was diagnosed at just the right timetwo

    weeks after the arrival of the fetal intervention team to Texas

    Childrens Fetal Center.

    A NEW MODEL OF CARE FOR MOTHERS AND BABIES

    Recruited in 2006 from the University of North Carolina,

    Chapel Hill, the fetal intervention team of Moise, Anthony

    Johnson, D.O., and coordinator Karen Moise, R.N., came toHouston to establish and operate this much needed service.

    Prior to their arrival, there were no such services provided

    in the central part of the country, said Karen Moise. If Anayele

    would have not had the resources to travel to San Francisco

    or Pennsylvania, it is highly likely that she would have lost

    the pregnancy.

    During Martinez treatment in 2007, she was transferred to

    the St. Lukes Labor and Delivery Unit, staffed by Texas

    Childrens. By 2011, however, mothers with this kind of

    condition and other pregnancy complications will have the

    opportunity to be treated at Texas Childrens Maternity Center,

    currently under construction. The center will provide the finest

    prenatal and obstetrical care to women and perinatal care for their

    babiesall in one state-of-the-art facility.

    Along with Baylor College of Medicine, Texas Childrens is

    assembling a team of physicians and administrators to lead the

    Maternity Center and actively recruiting medical staff that will be

    focused on high-risk deliveries.

    The fetal intervention team is especially excited about the

    arrival of the Maternity Center. The unique services of Texas

    Childrens Fetal Center will be provided to patients in one

    location on the fourth floor of the new center. There patients can

    receive the expertise of perinatal specialists as well as a broad

    spectrum of pediatric subspecialists who will care for their unborn

    child after birth. We are excited to be a part of this world-class

    opportunity, Moise said.

    SAVING TWO TINY LIVES

    Once diagnosed, Martinez was briefed on the best option to

    save her childrena procedure called laser photocoagulation.

    The procedure requires doctors to make a small incision in the

    skin over the uterus through which a very small telescope, called

    a fetoscope, with a small laser fiber is inserted directly into the

    recipient twins pregnancy sac. The fetoscope is used to look at the

    blood vessels on the surface of the placenta. Vessels that are found

    to communicate between the twins are then disconnected with

    the laser energy. This process is followed by the removal of the

    extra amniotic fluid around the recipient twins sac to achieve a

    normal volume.

    Prior to the surgery Martinez said she understood

    that the risks were great, but so were the possible rewards.

    According to Johnson and Moise it takes about 75 cases for

    a surgical team to reach peak performance with laser

    photocoagulation. Once that is achieved 50-60 percent of the

    time the mother will take home two babies, approximately

    20-30 percent of the time she will take home one baby,

    and about 20 percent, or less, of the time she will take home

    no babies.

    I heard the risks and statistics, but Dr. Moise also told me

    his intentions, Martinez said. He told me the goal was to go in

    and get two healthy babies. I believed in him, and I believed in

    my boys. He told me that if we were a praying family this was the

    time to start praying.

    Prayers were answered when Martinez surgery was

    completed without complication. However, she did require strict

    bed rest for three months after going into pre-term labor a few

    weeks later. While on bed rest I just kept talking to my boys and

    telling them to keep growing, Martinez said. I would get

    depressed, and then I would feel them kicking in there and

    reminding me that I wasnt alone. We were all fighting together. I

    have some brave little boys. They never gave up.

    The Martinez twins were delivered by c-section in March

    2007 and are now 15 months old.

    ANGELS OF MEDICINE

    Johnson said he cannot stress enough how important

    it is for patients to be their own best advocates in these

    situations. TTTS is a very bad disease. If you do

    nothing, there is a 90 percent mortality rate, he said. It is

    important to ask the right questions. If you are pregnant

    with twins then ask if there is one placenta or two.

    Johnson further recommended that mothers carrying

    monochorioinc or twins with one placenta receive an ultrasound

    every two weeks and are also seen by a maternal-fetal medicine

    specialist in addition to their regular obstetrician.

    Patients need to stay informed because most obstetricians

    will only see about two to three cases of TTTS in their careers,

    added Moise, and they may not know exactly what the signs

    are right away.

    All the more reason for mothers to have a resource to turn to

    like Texas Childrens Maternity Center.

    Including the Martinez procedure, Johnson and Moise have

    performed approximately 100 laser photocoagulation surgeries,

    and counting. The team attributes much of its success to the envi-

    ronment Texas Childrens Hospital has provided.

    Anytime we need to do a surgery, we have the staff, space

    and resources24/7, Karen Moise said. She added that the fetal

    intervention team is greatly supported by a trained group of

    nurses and other professionals. The support is especially

    welcoming since Texas Childrens Hospital has been in the

    childrens business. These are moms, adults, so its a different

    realm for them, but we always have everything we need.

    Johnson and Moise both said they often have to pinch

    themselves when they think about their teams progress

    and possibilities within Texas Childrens and with the new

    Maternity Center.

    At Texas Childrens Hospital the priority is always the

    patient and decisions are made around that central focus,

    Johnson said.

    Martinez couldnt agree more. Today she has two healthy

    15-month-old boys who are active, alert and developing normally.

    I was a single mom trying to get through a very difficult

    situation on my own, she said. Dr. Moise and Dr. Johnson not

    only saved my boys but were there for me every step of the way.

    They are my angels.

    10 | TEXAS CHILDRENS HOSPITAL www.texaschildrens.org

    While on bed rest I just kept talking to my boys and telling them

    to keep growing. I would get depres sed, and t hen I would feel them kicking in there

    and reminding me that I wasnt alone. We were all fighting together.

    Anayele Martinez

    Drs. Anthony Johnson and Kenneth Moise

    TWIN TRIUMPH

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    the way homeFOR HIGH-RISK INFANTS, GETTING HOME FROM THE HOSPITAL

    CAN BE A LONG ROAD PAVED WITH OBSTACLES, BUT TEXAS CHILDRENS

    DEVELOPMENTAL CARE PROGRAM IS HERE TO HELP WITH THE JOURNEY.

    12 | TEXAS CHILDRENS HOSPITAL www.texaschildrens.org

    Like most expecting moms, Kate Harrison anticipated the day

    when she would carry her seco nd child, Chloe, home to be with

    her family. On Oct. 6, 2007, she and her husband, Rex, drove

    to their local Wharton, Texas hospital for the long-awaited

    arrival. Little did they know that their babys first home would

    turn out to be the neonatal intensive care unit (NICU) at Texas

    Childrens Hospital.

    None of my prenatal exams indicated that Chloe had any

    health problems, and she was a near-term delivery, explained

    Harrison. After she was born, the doctors noticed what they

    thought was a cyst on the outside of her abdomen. Within two

    hours, she was transferred to Texas Childrens where she stayed for

    the next three months.

    Texas Childrens physicians quickly realized the cyst was

    actually part of her bladder, and Chloe was diagnosed with cloa-

    cal exstrophy, a rare condition. As their exams continued, doctors

    realized Chloe also had a congenital heart defect, one of her

    ankles had not developed, and her foot was severely deformed.

    Testing also showed that Chloe was missing the tip of chromo-

    some 1 that indicates she has Monosomy 1p35, a syndrome that

    can be characterized by developmental delay.

    At only 4-days-old, Chloe had surgery to begin addressing

    some of her health conditions. Due to complications and

    the forming of a fistula at the incision point, her stay at

    Texas Childrens extended much longer than originally anticipat-

    ed. Chloe was a patient for more than three months.

    BY HEATHER MCLEAN WIEDERHOEFT

    CHLOE AND KATE HARRISON

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    14 | TEXAS CHILDRENS HOSPITAL www.texaschildrens.org

    During that time, her treatment and recovery were prioritybut so

    was her continued developmental growth that is so critical for

    every newborn.

    Luckily for Chloe, she was one of the first Level 3 NICU

    patients to participate in Texas Childrens new developmental

    care program.

    Developmentally-supportive care primarily focuses on

    three areas for high-risk newborns: positioning of the infant, light

    and noise, explained LuAnn Papile, M.D., neonatologist who

    was recruited to Texas Childrens to develop this unique multidis-

    ciplinary program.

    From a physiologic standpoint, we try to determine what

    elements stress a newborn and find ways to limit the stress so the

    newborn can continue to develop. The key to this approach is the

    family-centered aspect. We work with the families so they can

    learn how to better read their babys cues and clues and learn how

    to approach their baby so when they eventually graduate from

    Texas Childrens, they have a much more successful transition

    home, said Papile.

    For example, during the final trimester, the growing infant

    is in a very flexed position in the womb which is a critical

    component for development, said Papile. Because pre-term

    newborns automatically adjust to the flat surfaces in their nurs-

    ery environment, the developmental care team works to keep the

    infant in the appropriate third trimester position to encourage

    better development.

    IT TAKES A TEAM

    Developmental rounds are a key part of the program.

    Different members of the teamincluding doctors, nurses,

    physical therapists, occupational therapists, social workers, clini-

    cal specialists, child-life therapistsmeet at least once a week to

    discuss each baby. Their goal is to work together as a team to

    ensure the babys developmental growth as well as the

    familys understanding.

    Everyone on the team has a different perspective about the

    baby and the family, explained Papile. As we share information,

    we are able to develop a holistic picture of what is going on with

    the baby and the family which should make the transition from

    the birth of a high-risk newborn to the infant eventually being

    discharged as smooth as possible.

    Carol Turnage-Carrier, M.S.N., R.N., newborn clinical

    nurse specialist, is a member of the team and has worked in the

    area of developmental care for 11 years.

    Until this program was launched, it was as if we had beenpreparing for Dr. Papile to join us so we could move forward.

    Working together with our staff and families, we are focusing on

    providing our babies the best opportunities that will lead to the

    best outcomes, said Turnage-Carrier.

    Marcia Berretta, licensed clinical social worker, coordinates

    follow-up with patients after they graduate from the hospital.

    Currently, the follow-up program only applies to high-risk infants

    who weighed less than 1,000 grams at birth or who received

    extracorporeal membrane oxygenation (ECMO). In the future,

    the program may extend to all newborns in Texas Childrens

    Level 3 NICU.

    We feel it is so important to maintain a relationship with all

    of the patients from this program so we can track how each infant

    is doing as well as provide

    support to the parents to

    help ensure their baby is

    developing as he or she

    should, Berretta said.

    Our follow-up clinic,

    which opened in late June,

    will provide us with

    real-time information on

    our patients. We can pro-

    vide support to parents

    who are anxious and help

    answer any of their ques-

    tions so they can continue

    to support their infants developmental progress.

    According to Ann Stark, M.D., chief of neonatology service,

    having this real-time information on all of the NICU graduates

    will be important to Texas Childrens ongoing efforts to improve

    care and outcomes for newborns. This program also is going to

    be greatly enhanced with the addition of Texas Childrens

    Maternity Center. The best outcomes are when you have a

    high-risk baby born in the same hospital where the NICU care is

    available. With moms being able to deliver at Texas Childrens

    instead of having to transfer their high-risk babies, well be

    creating a more ideal situation for treatment.

    HOME AT LAST

    For young Chloe and her family, her first several months of

    life were a true challengethe majority of her time spent in the

    hospital overcoming some tremendous hurdles.

    Today, Chloe is at home with her family and has begun her

    outpatient treatment through Texas Childrens Hospital.

    We would not be where we are today without the care

    Chloe received at Texas Childrens, said Harrison. Dr. Papiles

    developmental program gave us the tools we needed to

    help Chloe succeed developmentally. This is really one of the best

    hospitals in our country, and the developmental care program has

    meant so much to us.

    DR. ANN STARK

    FROM LEFT, CAROL TURNAGE-CARRIER, MARCIA BERRETTA AND DR. LUANN PAPILE.

    www.t exa sch ild rens .or g TEXA S CHI LDR ENS HOS PITAL | 15

    None of my prenatal exams indicated that Chloe had any health problems,

    and she was a near-term delivery. After she was born, the doctors noticed what they

    thought was a cyst on the outside of her abdomen. Within two hours, she was

    transferred to Texas Childrens where she stayed for the next three months.

    Kate Harrison

    the way home

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    www.t exa sch ild rens .or g TEX AS CHI LDR ENS HOS PITAL | 1 7

    A NEW LOOK AT

    HEREDITY

    Researchers at Texas Childrens Hospital

    and Baylor College of Medicine are investigating

    how a womans diet during pregnancy may affect

    her childs health throughout his or her lifetime.

    BY SHANNON RASP

    All babies are born with much of their biological profile predeterminedhow

    tall they will be, if they will have curly hair or straight, if they are predisposed

    to being slender or obese. But recent discoveries in the field of epigenetics are

    causing some researchers like Kjersti Aagaard, M.D., Ph.D., to question previously

    accepted ideas about heredity. Epigenetics is the study of heritable changes in

    gene function that occur without a change in the DNA sequence.

    Is it possible, Aagaard and her associates at Baylor College of Medicine wonder,

    to alter a persons inherited traits while he or she is still a developing fetus? Can sim-

    ple changes to a pregnant womans diet, for instance, help her offspring lead a

    healthier life?

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    18 | TEXAS CHILDRENS HOSPITAL www.texaschildrens.org

    Aagaard, an assistant professor of maternal and fetal medi-

    cine who sees patients at Baylor and St. Lukes Episcopal Hospital

    in partnership with Texas Childrens Hospital, is fascinated by the

    link between a mothers health and that of her offspring.

    Ive always been interested in understanding the relationship

    between the most common exposures encountered in pregnancy

    and how it affects the next generations health, she said. It is

    really evolution on a shortened scale. You can appreciate how a

    pregnant womans health and wellbeing affects that of her child,

    both in the immediate time after delivery and quite probably

    throughout the life of that same child.

    H ISTORY RA ISES IMPORTANT QUEST IONS

    Aagaard traces her interest in this particular research to

    reading a scientific report on the health of the children born to

    women who suffered through the 1944-1945 famine in The

    Netherlands. The German forces occupying the country at the

    time blocked food deliveries to the western half; combined with

    an unusually harsh winter, the situation resulted in the starvation

    deaths of over 18,000 Dutch people.

    The pregnant women who lived through the famine

    delivered, not surprisingly, very small babies. However, when

    those children grew up, they were disproportionately overweight

    with high rates of diabetes, cardiovascular and pulmonary disease,

    high cholesterol and other weight-related illnesses.

    What made these people, who started out so tiny, grow to be so

    large? Scientists believe that the malnutrition the women suffered

    somehow caused profound reprogramming changes to their babies

    in utero. The womens bodies communicated to the embryos that

    food was scarce and of low nutritional value, so the babys genetic

    makeup programmed its body to store fat in large amounts.

    By the time the children were born, The Netherlands had

    been liberated and food became abundant. But by then, the

    childrens fate had been secured-their bodies would store fat,

    reduce insulin secretion, and otherwise protect them from a

    famine that no longer existed.

    This example, in combination with a large number of other

    epidemiology studies as well as observations from animal

    models, have led the medical and scientific community to coin

    the term developmental origins of adult disease to explain

    the phenomena.

    EAT ING FORTHE NEXT GENERATION

    What does all of this mean for moms? Aagaard and others theo-

    rize that what a woman eats during pregnancy can not only affect her

    childs health at birth, but also affect it throughout his or her lifetime.

    While your genes provide the basic building blocks, they dont

    necessarily create the final heritable code, said Aagaard. Outside

    influences can change the way in which genes are expressed.

    As an example, she explained, she is studying histone changes

    in rodent models. Histones are the chief protein components of

    chromatin, which act as the spools DNA winds around and play

    a role in gene regulation. Aagaard and her colleagues have discov-

    ered these changes not only can be transmitted across generations

    but also can be modified by nutrition. They observed that

    supplementing essential nutrients in the first generation of

    offspring from childhood through pregnancy and lactation can

    reverse these changes in the next generation.

    We found that a diet supplemented with essential nutrients,

    yet unaltered in its caloric content, prevents adult metabolic

    disease and can reprogram the offsprings genes, she said.

    Aagaard and her colleagues also are studying the effects of a

    high fat diet and obesity on development. Given our current adult

    epidemic of obesity and the rise in juvenile diabetes and childhood

    obesity, we were curious whether the framework for obesity was

    being laid out in pregnancy or early lactation. We were especially

    interested in looking at this issue in a primate model, with the hope

    of eventually using our findings clinically to benefit patients.

    Aagaard and her co-authors from the University of Utah

    teamed up with researchers at the Oregon National Primate

    Research Center. In their studies, recently published in the

    Journal of Molecular Endocrinolog y, primates were placed

    on control and high fat diets for up to five years. Over the course

    of the study, many of the animals became obese. However,

    Aagaard and her team learned that even in the absence of

    maternal obesity, the high fat diet still affected the offspring.

    Whether the moms were on the diet for two years or four

    years, their offspring developed non-alcoholic fatty liver disease,

    Aagaard said. Moreover, if we put obese moms back on a control

    diet after five years, there was some improvement among their

    offspring following the diet reversal. These changes were accom-

    panied by a significant change in the histone code, which is also

    associated with changes in the expression of a number of genes.

    BUILD ING HEALTHIER L IVES

    Though still gathering and sorting data, Aagaard said they

    hope to have answers within five years.

    Giving people a better chance of living a healthier life

    may be as simple as cutting down on high-fat foods or taking

    a nutritional supplement, said Aagaard. We are finding

    that simple interventions could potentially cut the rate of

    obesity dramatically in the next generation and decrease the risk

    for developing diabetes, hypertension and cardiovascular

    and lipid diseases.

    Providing women with such interventions is one of the goals

    of the new Texas Childrens Maternity Center, currently under

    construction. The center not only will combine the clinical

    advantages of Baylor and Texas Childrens, but also the significant

    research strengths of both institutions, according to Amy Young,

    M.D., executive vice chair and director of general obstetrics at

    Baylor and Texas Childrens Maternity Center leader.

    Young said, The Maternity Center will enable us to bring

    the laboratory to the bedside to more effectively translate this

    kind of current research activity into meaningful patient care and

    improved outcomes.

    Currently, Aagaard is taking her research in new directions,

    using large databases and preserved human samples to investigate

    the effects of tobacco use and air quality on developing fetuses.

    My work is focused on understanding how we can use

    these unique early periods in human development to help people

    live longer, healthier and more enjoyable lives, Aagaard

    explained. Advances in our understanding hopefully will enable

    us to treat common adult diseases at potentially their earliest

    point-before birth.

    That vision is shared by Texas Childrens Maternity Center,

    added Young We are caring for women at every stage in their

    livesits the circle of life, and answers like those Dr. Aagaard is

    uncovering will have important implications at every turn. The

    ultimate goal is to build a better quality of life for the generations

    that follow.

    www.t exa sch ild rens .or g TEX AS CHI LDR ENS HOS PITAL | 19

    A NEW LOOK AT

    HEREDITY

    The Maternity Center will enable us to bring thelaboratory to the bedside to more effectively

    translate this kind of current research activity into

    meaningful patient care and improved outcomes.

    DR . AMY YOUNG

    We found that a diet supplemented withessential nutrients, yet unaltered in its caloric

    content, prevents adult metabolic disease

    and can reprogram the offsprings genes.

    D R . K J E R ST I A A G A A R D

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    The Brown Foundation, Inc. commits $10 millionto Texas Childrens campaignBY ANN SAYE

    Historic Gift to Help Heal Sick Children

    In May 2008, Texas Childrens Hospital received word that

    it would be receiving the second largest gift commitment in

    its history$10 million from The Brown Foundation, Inc.to

    support the Heal Sick Children campaign. The funds will be

    dedicated to Texas Childrens Maternity Center and to the Jan and

    Dan Duncan Neurological Research Institute, two of the most

    pronounced campaign priorities.

    The Brown Foundation, Inc. has been serving the Houston

    community for nearly 60 years and has contributed to Texas

    Childrens since 1962, totaling more than $23 million in gifts and

    commitments, noted Ralph D. Feigin, M.D., physician-in-chief

    at Texas Childrens Hospital. Over the years, the trustees

    generosity has made an impact throughout the hospital, with

    gifts to support each of Texas Childrens previous campaigns in

    addition to Texas Childrens Cancer Center, infectious diseases,

    autistic spectrum disorders, the congenital heart surgery service

    and many other areas. This outstanding new commitment will

    have an even more far-reaching effect.

    The Brown Foundation, Inc. was founded in July 1951 by

    Herman and Margarett Root Brown and George R. and Alice

    Pratt Brown. As of last summer, the foundation had awarded more

    than $1.1 billion in grants, approximately 80 percent of which

    were awarded within the state of Texas, with special emphasis on

    the city of Houston.

    Since its inception, the foundation has given to programs

    that address root causes rather than symptoms, stimulate

    collaborative effort and create long-lasting impact beyond the

    value of the actual grant.

    We believe that Texas Childrens Maternity Center and the

    J d D D N l i l R h I i h

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    ConocoPhillips pledges $3 millionto help children in Houston and around the worldBY ANGELA DOLDER

    LEADE

    RSINGIVING

    For Families Near and Far

    Texas Childrens Physician-in-Chief Dr. Ralph D. Feigin, President and CEO Mark A. Wallace, and

    ConocoPhillips Chairman and CEO Jim Mulva break ground with help from Texas Childrens patients.

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    Simmons Family Foundation gives $3 million

    to create collaborative research fundBY ANGELA DOLDER

    L.E. and Virginia Simmons have added a new chapter

    to their familys legacy of support for Texas Childrens

    Hospital, and two other Texas Medical Center

    institutions, with a commitment of $3 million to

    bli h h Si F il F d i

    with new ideas, such as junior researchers who require

    financial support to jump-start their projects and

    experienced investigators who might not otherwise

    collaborate with their counterparts at other institutions.

    T i i ll i i ifi i h

    L.E. and Virginia Simmons

    with their children,

    William and Virginia

    Pursuing Partnerships

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    Fares family commits $250,000 to advance neurological researchBY ANGELA DOLDER

    In a Fathers Footsteps

    Nijad I. Fares learned early on that giving to others is an impor-

    tant aspect of lifeits a lesson he attributes to his father, Issam.

    True to his fathers vision, Fares and his wife, Zeina, have

    given back in a big way, committing $250,000 to the Jan and

    Dan Duncan Neurological Research Institute at Texas

    Childrens Hospital.

    The Fares gift will establish the Issam M. Fares Family

    Lectureship at the Institute, in honor of the patriarch. My

    father is my best friend and I am glad to recognize him, while at

    the same time, give hope to millions of children and families

    who are afflicted by neurological disease, said Fares.

    Worldwide, one billion people, including 300 million

    children, suffer from some form of the more than 600 disorders

    that afflict the nervous system.

    The Jan and Dan Duncan Neurological Research Institute

    ill b h fi f ili i d di d l i h

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    H-E-B Tournament of Championsgives $500,000 to congenital heart surgeryBY TRAVIS MCCLAIN

    Ensuring the Best Care for Tiny Hearts

    LEADERS IN GIVING

    Thanks to a $500,000 gift from the 2008 H-E-B Tournament of

    Champions, Texas Childrens congenital heart surgery service is

    advancing its efforts to heal sick children with heart defects.

    Now in its 23rd year, the H-E-B Tournament of

    Championsa three-day series of events at tennis courts and golf

    courses across San Antonioprovides an opportunity for vendors,

    who supply H-E-B with products and services, to get actively

    involved in supporting organizations across Texas.

    Led by Charles D. Fraser, Jr., Texas Childrens congenital

    heart surgery service is the only one of its kind in Texas. Pediatric

    h h b f d T Child H i l

    Dr. Fraser and his team are making an invaluable contri-

    bution to the science of pediatric heart surgery, and we are pleased

    to support their efforts, said Winell Herron, H-E-B Tournament

    of Champions trustee.

    Texas Childrens is fortunate to have the commitment of

    generous community partners like the H-E-B Tournament of

    Champions, said Mark Wallace, president and chief executive

    officer of Texas Childrens Hospital. This gift will help accelerate

    Dr. Frasers vision for the congenital heart surgery service,

    ultimately advancing research and ensuring the best, most

    i i f i h

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    Without The Pin Oak Charity Horse Show, there might not be

    the Texas Childrens Hospital known today. And now, Pin Oak is

    helping launch the Texas Childrens of tomorrow.

    Th Pi O k Ch i H Sh i

    Horse Show debuted in 1945 and was soon one of the preemi-

    nent horse shows in the nation. Today, with support from its pre-

    senting sponsor Compass Bank Wealth Management Group, it

    h b h fi h b i d b h U S

    Shaping the Future

    The Pin Oak Charity Horse Showpledges $300,000 to new West CampusBY KATHY ISDALE

    From left, standing, William, Joseph and Eva

    Bisso, Pin Oak executive board member;

    Barbara Stewart, Compass Bank Wealth

    Management Group advisor; Ed Perwein,

    Pin Oak participant since its earliest days;

    the award-winning horse MacArthur Park;

    Lynn Walsh, Pin Oak president; Fiona Dawson,

    assistant vice president with Compass Bank;

    (kneeling, left) Wendy Cook, Pin Oak

    managing director; and Susan Pelletier,

    Pin Oak executive board member

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    On The SceneOn The Scene

    28 | TEXAS CHILDRENS HOSPITAL www.texaschildrens.org www.texaschildrens.org TEXAS CHILDRENS HOSPITAL | 29

    On February 26, Texas Childrens hosted its fourth annual An Evening

    with a Texas Legend, presented by Wachovia and honoring medical legend

    Denton A. Cooley, M.D. (right). More than 600 guests gathered at Hilton

    Americas-Houston to hear CNN host Larry King (left) interview Cool ey about

    his life and many pioneering accomplishments. The event, chaired by Janet and

    Tom Walker, raised almost $450,000 for Texas Childrens Cancer Center .

    Meg Goodman and Mike Bonini graciously hosted a reception in their home

    several nights before the event to honor the top underwriters and sponsors.

    From left, Shannon and Mark A. Wallace,president and CEO of Texas Childrens

    Hospital; Terri, Prentiss and John Havens;

    and Helen and Charles D. Fraser, Jr., M.D.,

    chief of congenital heart surgery at Texas

    Childrens, were among the crowd of nearly

    400 who gathered at the Havenses historic

    home for the second annual Frasers

    Friends event in April. At the event, the

    Havenses shared the story of how their son

    Prentiss was born with a congenital heart

    defect, Tetralogy of Fallot, and how Fraser

    and his team repaired his tiny heart to save

    his life. The 2008 Frasers Friends event

    has helped raise more than $450,000 toadvance the priorities of the Texas

    Childrens congenital heart surgery team.

    Nearly 1,000 children and adults ran in the 10th annual Davids

    Dream Run in May 2008, put on by David Elementary School PTO

    in The Woodlands. The school and the run are named after David

    Vetter, the Bubble Boy, who was born with severe combined

    immune deficiency (SCID). This years run raised more than $20,000

    for Texas Childrensbringing the schools total giving to the hospital

    to more than $270,000. Recently, Davids family including (from left)

    his nephew Cameron David Canion, sister Katherine Canion and

    mother Carol Ann Demaret gathered at Texas Childrens with

    Lee Allen, principal of David Elementary School, and Davids DreamRun volunteers Sandra Fuentes and Michelle Barrell to celebrate

    the unveiling of the commemorative wall for the David Center for

    allergy and immunology.

    Mark A. Wallace, president and CEO of

    Texas Childrens, joins event emcees Shara Fryer,

    KTRK news anchor, and Nancy Ames, owner

    and founder of Ward & Ames Special Events.

    Cancer Center patient Sabrina Hunter, 3,

    gets entertained by Lori Vetters, regional

    president of the Gulf Coast region at Wachovia,

    and Legend honoree Denton A. Cooley, M.D.

    Right, Event Chair Janet Walker with Underwriter Chair Emily Crosswell.

    I M P O R T A N T D E V E L O P M E N T S

    Celebrating Dr. Denton Cooleya world-renowned Texas Legend Frasers Friends launch another year of support

    Davids dream lives on

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    www.t exa sch ild rens .or g TEX AS CHIL DRE NS HOS PITAL | 3130 | TEXAS CHILDRENS HOSPITAL www.texaschildrens.org

    On The SceneOn The SceneIn April, Carousel, Young Friends of Texas Childrens Cancer Center, hosted more

    than 650 guests, including (from left) David Poplack, M.D., director of TexasChildrens Cancer Center; Audry Black, and her mother and event

    committee co-chair, Kim; Maggie Stacy, event chairman, and her husband, Will, for

    the Give a Hand to Raising the Roof family fun event at the Houston Zoo.

    The event grossed more than $200,000 for Texas Childrens Cancer Center, and

    participating families had the chance to finger-paint on ceiling tiles to help decorate

    the roofs of Cancer Center patient rooms at the hospital.

    Carousel rounds up support for pediatric cancer

    By donating $1 at a time, Randalls customers and associates helped

    raise $84,863 for the pediatric gene research program at Texas

    Childrens Cancer Center through the 2008 Kindness for Kids

    campaign, in partnership with the Houston Chronicle. The Clear Lake

    store alone raised $6,406the most of all the local Randalls stores.

    At the official check presentation, (from left) Jack Sweeny, president

    and publisher of the Houston Chronicle, Ralph D. Feigin, M.D.,

    Texas Childrens physician-in-chief, Tom Schwilke, Randalls president,

    and ZoAnn Dreyer, M.D., director of the Cancer Centers long-term

    survivor program, congratulated Randalls Clear Lake store employees David LaCour, store director, Sandy Crowder, customer service

    supervisor, and Byron Myers, assistant store director, on their incredible success and generosity.

    Randalls shows its kindness for kids

    For the second year in a row,

    Wal-Mart achieved its goal of

    raising $10 million for Childrens

    Miracle Network nationwidethis time, in just eight weeks. Stores in the greater Houston area

    raised $264,340 during the campaignall going to support Texas Childrens Hospital.

    Wal-Mart continues to rally

    for Childrens Miracle Network

    Top left, Wal-Mart Supercenter #2993 in Sugar Land

    hosted a kickoff for the national fundraising effort, where

    store manager Jesse Thompson (left) and Kevin Kline,

    morning show DJ on The New 93Q (right, pushing cart),

    helped Texas Childrens patient Mary Jo Stavinoha, 8, select

    $1,000 worth of donated toys and craft supplies to give to

    patients at the hospital. Right, Wal-Mart Distribution 7010

    employees including (from left) Wendy Bowan, training

    manager, Rick Johnson, transportation manager, and Adam

    Gilliam, human resources manager, helped host the third annual Childrens Miracle Network Golf Tournament and

    raised more than $10,000 to help Texas Childrens patients and families like Norma Dean (far right)

    and her daughter, Rylee (center). Bottom left, Last year, Wal-Mart Supercenter #400 in Conroe was the top

    fundraising store in the Houston market, collecting more than $20,900 for Childrens Miracle Network

    thanks to the efforts of associates like (from left) Susan McDowell, Marie Thurmon and Cheryl Garrett.

    This spring, Houston Junior Womans Club members and guests, including (from left)

    Dianne Demny and Brenda Werner, 2007 fundraising chairs; Debbie Bauer, 2007 HJWC

    president; and Nancy Shomette, 2008 HJWC president, celebrated their 40th anniversary at the

    annual Donations Coffee. The event was a celebration of HJWCs longtime dedication to childrenand successful fundraising in 2007. Thanks to funds raised through HJWCs 24th annual Holiday

    Happening, their first annual golf tournament and charitable fund contributions, the organization

    was able to award more than $254,000 to 17 Houston area childrens charities, including $72,645 to Texas Childrens Cancer Center.

    HJWC celebrates 40 years of dedication to children

    In Spring 2008, the Theta Charity Antiques Show of the Houston Alumnae of Kappa Alpha

    Theta donated $196,935 to permanently endow the annual lecture series they established at

    Texas Childrens, now named The Donald J. Fernbach, M.D., Endowed Lecture Series,

    presented by the Houston Alumnae of Kappa Alpha Theta. Recently, Theta alumni (from left)

    Carol Herder, president, Liz Rigney, philanthropic committee chair, and Janet Lionberger, 2007

    Theta Charity Antiques Show chair, joined lecture namesake Fernbach and David D. Poplack,

    M.D., director of Texas Childrens Cancer Center, to unveil a special plaque at the hospital honoring the Theta Charity Antiques Show.

    Thetas show support for pediatric faculty training

    Photo by Alexanders Fine Portrait Design

    This summer, all 98 greater Houston area Kroger Food

    Stores participated in the companys Childrens Miracle

    Network miracle balloon campaign. Thanks to the efforts

    of many employeeslike District Manager Jeff Roberson

    (back row, center) and his District 2 store representa-

    tivesKroger raised more than $100,000 for TexasChildrens Hospital. Roberson and his team visited the

    hospital prior to the campaign, gaining inspiration from

    seeing firsthand where the money they help raise goes.

    Kroger miracle balloons rise to the top

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    Most people may not think to name Texas Childrens

    Hospital as the beneficiary of an IRA. After spending

    many hours at Texas Childrens with his granddaughter,

    Jackson O. Wilson did.

    Wilsons 9-year-old granddaughter, Emily Otto, was

    diagnosed with cystic fibrosis almost immediately after she was

    born and spent her first three months of life in Texas Childrens

    neonatal intensive care unit.

    Emilys been in and out of Texas Childrens ever since,

    Wilson says. Ive been up there with her numerous times and

    have seen the good work they do. It was an easy decision to

    support Texas Childrens.

    Wilson and his late wife, who had severe multiple scle-

    rosis (MS), retired to Houston three years prior to her death in

    2005. He recently remarried, and his wife, Marion, has become just as doting a grandmother to his grandchildren as she is to her own.

    l h h f d h h l h h l l dd h h b k Th l l

    GIVING TO

    A WORTHYCAUSEBY KATHY ISDALE

    PLANNED GIVING

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    G R A T E F U L F A M I L Y

    MAUREEN DIMARCO:GRATEFUL GRANDMOTHER

    My daughter, Noelle Reed, was hospitalized this past March for almost four weeks while she was pregnant with triplets. She suffered

    from cholestasis and preeclampsia, and one of the babies was diagnosed with intrauterine growth restriction (IUGR), meaning she was

    small for her gestational age. As a result, Noelle was in great discomfort, and of course she was very anxious about keeping the

    pregnancy going long enough for the babies to survive and do well.

    We will never be able to say enough superlatives about her physician, Dr. Robert Carpenterhis skill and care (and his wicked sense

    of humor). His medical skill is certainly the main reason my daughter and her husband are now the very proud parents of three healthy

    babies who have had remarkably few difficulties other than simply

    needing to grow.

    But Im not writing just to praise Dr Carpenter; rather, I want to

    explain that the other critical part of this success story is the Texas

    Childrens nurses and staff who operate the Labor and Delivery Unit

    at St. Lukes.

    With no exceptions, every nurse and clerical staff member was

    phenomenal. And after four weeks I think we knew every single

    person there whether full-time or part-time. They are clearly the elite

    of the nursing corps and take pride in their skill and also in their

    ability to relate to each patient and truly make a difficult time as easy

    as possible. Their care was always delivered with warmth, patience

    and understanding of the physical and emotional stresses their patient

    k h ld h

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    CALENDAR

    Texas Childrens Hospital

    832-824-1000

    Development Office

    832-824-2107

    Texas Childrens Health Plan

    1-800-990-8247

    Texas Childrens Pediatric

    Associates Referral Line

    832-824-7700

    Texas Childrens

    Home Health Services

    832-824-2400

    Texas Childrens International

    832-824-1138

    Texas Childrens Health Centers832-824-2868

    September 20, 2008

    Nicholas Alexander Higgins

    Memorial Golf Tournament

    benefiting Texas Childrens Heart Center

    Wildcat Golf Club

    September 25, 2008

    Lewis Jewelers An Emerald Evening

    benefiting Texas Childrens Renal Dialysis Center

    Lewis Jewelers in Webster, Texas

    September - December 2008

    Kris Browns Kick Club

    benefiting Texas Childrens Charity Care

    For information on any of these events, please contact the Office of Development at 832-824-6818

    or e-mail [email protected].

    Now online at www.shine.texaschildrens.org

    COMMUNITY EVENTS

    BENEFITING TEXAS CHILDRENSSeptember 25, 2008

    Celebration of Champions

    benefiting Texas Childrens Cancer Center

    Hilton Americas Houston

    October 14, 2008

    The Bad Pants Open

    benefiting Texas Childrens Newborn Center

    Cypresswood Golf Club

    November 18, 2008

    Whats Up, Doc?

    benefiting Generation to Generation

    River Oaks Country Club

    TEXAS CHILDRENS HOSPITAL EVENTS