Serological Diagnosis Of Viral

Hepatitis.

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1.1 - What is viral Hepatitis?Viral Hepatitis is a systemic disease, which primarily affects the liver. Viral

hepatitis is caused by one of the following pathogens:

Hepatitis A virus (HAV) .

Hepatitis B virus (HBV) .

Hepatitis C virus (HCV).

Hepatitis D virus (HDV).

Hepatitis E virus (HEV).

Hepatitis G virus (HGV)

ClinicallyClinically, it is difficult to make a reliable clinical distinction among cases

caused by the hepatitis viruses, so, only serologic tests can distinguish

these different types of viral hepatitis.amna alotiby

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2.2.3 - Serological test patterns HBV :

Test

Interpretation HBs AgHBs AbHBe AgHBe AbHBc total

Anti-HBc 1gM

+-----.Early acute HBV or Late

incubation.

+-+---Early acute HBV, Highly infectious

+-+-++Acute HBV

---+++Convalescence

-+-+++Early recovery

-+-++-Recovery

+-±± +

-Chronic infection (Chronic carrier)

----+-History of HBV infection Without

immunity

-+-

-+-

History of HBV infection With immunity

-+----HBV vaccination or Passive

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