Sepsis in the Hospital - acoi.org · BS_, Bernhard Knoblich, WD, Edward Peterson, PhD. and Michael...
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Transcript of Sepsis in the Hospital - acoi.org · BS_, Bernhard Knoblich, WD, Edward Peterson, PhD. and Michael...
• EGDT was devised by Emanuel Rivers, et. al. in 2001 with the goal of intensive monitoring and aggressive management of hemodynamics in a septic patient with a high risk of morbidity and mortality• For a time, this formed the basis of the
initial “Surviving Sepsis” campaign
• Subsequent to this – several studies have been published reporting that the concepts of EGDT should be abandoned• ProCESS, ARISE, ProMISE trials – large,
multicenter studies demonstrated no benefit of expensive, invasive management in sepsis patients