Sem 01, week-07 cbl

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F O U N D AT I O N M O D U L E C B L S EM - 01 , W EE K- 0 7 ( 16 - 1 2 - 2 0 13 ) C B L- 0 3 ASI\D:\WEEKLY TIME TABLES\051=16-12-2013 Page 1 of 2 C ASE : 13 year old girl has come to the doctor’s office with her mother. Her mother is worried about irregularity in the menstrual cycle. She says that the cycles are infrequent that is occurring every 5 to 6 weeks, she also complains that sometimes the bleeding continues for 10-15 days. Her mother is very anxious and seeks advice. On history mother explains the doctor that: Menarche was 6 months back She is at present in the12 th day of her current menstrual cycle Secondary sexual characters are well developed Her blood reports show: FSH 10.5 IU/L N= (6.42 IU/L) Estrogen100 IU/L N=(149.74 IU/L) LH 1.00 IU/L N=(3.96 IU/L) Progesterone 0.01 IU/L N=(0.64 IU/L) Q1. What is DUB? Q2. What is the differential diagnosisin this patient? Q3. What other tests should be further carried out ? Q4. What could be the commonest cause of hypothalamic dysfunction in this patient?

Transcript of Sem 01, week-07 cbl

Page 1: Sem 01, week-07 cbl

F O UN DAT IO N MO DUL E C BL S EM- 01, W EEK- 0 7 ( 16- 1 2- 20 13)

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CASE :13 year old girl has come to the doctor’s office with her mother. Her mother is

worried about irregularity in the menstrual cycle. She says that the cycles are

infrequent that is occurring every 5 to 6 weeks, she also complains that

sometimes the bleeding continues for 10-15 days. Her mother is very anxious and

seeks advice.

On history mother explains the doctor

that: Menarche was 6 months back

She is at present in the12th day of her current menstrual cycle

Secondary sexual characters are well developed

Her blood reports show:

FSH 10.5 IU/L N= (6.42 IU/L)

Estrogen100 IU/L N=(149.74 IU/L)

LH 1.00 IU/L N=(3.96 IU/L)

Progesterone 0.01 IU/L N=(0.64 IU/L)Q1. What is DUB?

Q2. What is the differential diagnosisin this patient?

Q3. What other tests should be further carried out ?

Q4. What could be the commonest cause of hypothalamic dysfunction in this patient?

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F O UN DAT IO N MO DUL E C BL S EM- 01, W EEK- 0 7 ( 16- 1 2- 20 13)

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Q1) Why is this girls period irregular?

Q2) What do you expect to see in the endometrium and ovaries at this stage of the cycle?

Q3) What is LH surge or leutinization?

Q4) How the cyclical changes in ovary are related to phasic changes in the estrogen and progesterone?

Q5) What can be done for this patient?