ASRS 300CSRS 300

SRS 300 Product Manual Page 1 of 50

Doc. No. 031956-05 August 2007 2007 DIONEX

PRODUCT MANUAL

FOR THE

ANION SELF-REGENERATING SUPPRESSOR 300 (ASRS 300 (4-mm), P/N 064554) (ASRS 300 (2-mm), P/N 064555)

CATION SELF-REGENERATING SUPPRESSOR 300

(CSRS 300 (4-mm), P/N 064556) (CSRS 300 (2-mm), P/N 064557)

Dionex Corporation, 2007 Document No. 031956

Revision 05 August 2007

SRS 300 Product Manual Page 2 of 50

Doc. No. 031956-05 August 2007 2007 DIONEX

TABLE OF CONTENTS 1. INTRODUCTION..............................................................................................................................................................4

1.1. Self-Regenerating Suppressor ...................................................................................................................................................... 4 1.2. Overview of Suppression Modes.................................................................................................................................................. 7 1.3. Mode of Operation Selection........................................................................................................................................................ 7

1.3.1. The AutoSuppression Recycle Mode......................................................................................................................................................... 8 1.3.2. The AutoSuppression External Water Mode ............................................................................................................................................. 8 1.3.3. The Chemical Suppression Mode .............................................................................................................................................................. 8 1.3.4. The MPIC Suppression Mode.................................................................................................................................................................. 11

2. INSTALLATION .............................................................................................................................................................12 2.1. System Requirements ................................................................................................................................................................. 12 2.2. Self-Regenerating Suppressor Control ....................................................................................................................................... 13

2.2.1. Reagent-Free Controller (RFC) ............................................................................................................................................................... 13 2.3. Back Pressure Coils for the SRS 300.......................................................................................................................................... 14

2.3.1. Assembly .................................................................................................................................................................................................. 14 2.4. Gas Separator Waste Tube for the SRS 300 ............................................................................................................................... 15

2.4.1. Assembly .................................................................................................................................................................................................. 15 2.5. Self-Regenerating Suppressor Current Selection........................................................................................................................ 15

2.5.1. Calculating the Correct Current Setting................................................................................................................................................... 15 3. OPERATION....................................................................................................................................................................17

3.1. Chemical Purity Requirements ................................................................................................................................................... 17 3.1.1. Inorganic Chemicals................................................................................................................................................................................. 17 3.1.2. Solvents .................................................................................................................................................................................................... 17 3.1.3. Deionized Water....................................................................................................................................................................................... 17

3.2. Start-up ....................................................................................................................................................................................... 17 3.2.1. Hydration.................................................................................................................................................................................................. 18 3.2.2. Back Pressure Coil Pressure Test............................................................................................................................................................. 19 3.2.3. Quick Back Pressure Check..................................................................................................................................................................... 19

3.3. Plum ing for the AutoSuppression Recycle Mode Operation .................................................................................................... 20 b3.3.1. Eluent Flow Path Connections in the AutoSuppression Recycle Mode ................................................................................................. 20 3.3.2. Regenerant Flow Path Connections in the AutoSuppression Recycle Mode.......................................................................................... 21 3.3.3. Installation in Thermal Chamber ............................................................................................................................................................. 21 3.3.4. Installation in ICS 3000 ........................................................................................................................................................................... 21

3.4. Plumbing for the AutoSuppression External Water Mode Operation......................................................................................... 22 3.4.1. Eluent Flow Path Connections for the AutoSuppression External Water Mode .................................................................................... 22 3.4.2. Regenerant Flow Path Connections in the AutoSuppression External Water Mode .............................................................................. 23 3.4.3. Regenerant Flow Path Connections in the AutoSuppression External Water Mode with Peristaltic Pump. ......................................... 24 3.4.4. Installation in Thermal Chamber ............................................................................................................................................................. 24

3.5. Plumbing for Chemical Suppression Mode Operation ............................................................................................................... 24 3.6. Plum ing for MPIC Suppression Mode Operation..................................................................................................................... 24 b

3.6.1. Eluent Flow Path Connections in MPIC Suppression Mode................................................................................................................... 24 3.6.2. Regenerant Flow Path Connections in MPIC Suppression Mode Using Pressurized Water Delivery System...................................... 24 3.6.3. MPIC Suppression Mode Operation........................................................................................................................................................ 25

3.7. Self-Regenerating Suppressor (SRS 300) Storage...................................................................................................................... 26 3.7.1. Short Term Storage (1 to 5 days) ............................................................................................................................................................. 26 3.7.2. Long Term Storage (More than 5 days)................................................................................................................................................... 26

4. TROUBLESHOOTING GUIDE.....................................................................................................................................27 4.1. Self-Regenerating Suppressor Operational Status Displays Alarm State ................................................................................... 27 4.2. Small or Increasing Analyte Peak Areas .................................................................................................................................... 28 4.3. High Background Conductivity .................................................................................................................................................. 29 4.4. Drifting Baseline .................................................................................................................................................................