Self-Injury Behavior (SIB)

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    Self-injurious Behavior

    A teenage boy with severe mental retardation,

    non verbal, who was demonstrating increasing

    self-injury. To the point where both his mother

    and the care team at the facility where he lives

    were at their wits end. He was already on

    multiple medications, including antipsychotics

    and clonidine.(Was his SIB a clue?)

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    Journal of Developmental & Behavioral

    Pediatrics (2010) discussed a similar

    case A 7 yo male with severe mental retardation

    and self-injurious behavior(hitting his facewith his fist, banging his head against the

    wall/floor/table. Increasing infrequency/intensity for the last 6 monthscausing bruising and swelling of his forehead.

    Parents reported that these behaviors wouldoccasionally occur due to frustration, butmore frequently occur for no reason at all.

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    Parents had tried verbal reprimands, andphysically restraining.

    PMH: AOM, constipation, GERD as an infant.

    Currently on no medications. Sleeps 9 hrs each night, no change in his appetite

    or sleep.

    Parents estimate he has ~ 20 words

    Lives at home with parents, 2 sibs. For the past 2years attended the same life skills class with 8other students

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    Physical exam shows no changes in his growth

    percentiles. No AOM. R side of his face is

    erythematous

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    The safety concerns for the patient and the

    disruptive effects of SIB on the family or

    caretakers creates a situation that requires

    immediate attention.

    h d l d d

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    Why do general pediatricians need to

    be comfortable taking care of these

    patients? Because you will be seeing more of them!!!

    (There will be more patients with self-injuriousbehaviors, and more of them will be managed inthe community)

    Recurrent SIB will be seen by primary carepediatricians, primarily in young children with

    autism and in adolescents with depression andcutting.

    Hopefully you will have a B&D pediatrician, childpsychologist, child psychiatrist for consultations.

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    Autism, for example. A recent 2010 AAP journal

    article, discusses how to evaluate GI disorders in

    patients with ASD. Often these patients are

    nonverbal and cannot describe their symptoms.

    These patients will present with vocal and motor

    behaviors, such as self-injury and aggression, as

    well as sleep disturbance and irritability. 5-17% of people with mental retardation and

    autism do serious harm to themselves by biting,

    pulling out hair, banging their head or gougingtheir eyes on a regular basis.

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    Medical intervention

    Chronic or acute health problems increase SIB. So it isvery important to diagnose and treat health conditionsthat are constantly aggravating the patient.

    Ear problems, sleep disturbance, and digestive/GI

    complaints(constipation, GERD) are the most commonculprits. Also want to rule out sinusitis, dentalproblems, migraine headaches, allergies,dysmenorrhea, seizures

    (This is the Pediatricians major role, but not necessarilyhis only role.)

    If no underlying medical condition is apparent, eval andtreatment just became more complicated.

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    Behaviorist Approach

    For some patients with intellectual deficits, SIB is their way ofcommunicating that something is wrong or they want to be left alone. (In~70% of SIB cases, individuals are using the behavior as a form ofcommunication)

    Can try to track antecedents and consequences of the behavior todetermine what the patient is trying to communicate. (Diary)

    Has anything changed in the patients world (home, school)

    SIB is very effective in eliciting attention.

    Teaching new strategies for expressing needs and relating to other peoplewould be the preferred intervention in this case

    (There are some studies that show 25% are refractory to behavioral

    intervention, in terms of long-term effects) Stimulation theory?

    Beta-endorphin release following SIB generates euphoric/anesthetic-likeeffect theory?

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    Medications

    When there is a chemical imbalance in the brain, treatmentmust include medication.

    There is no current drug that has been created specificallyfor SIB.

    There has been some success with Risperidone, anantipsychotic serotonin/dopamine modulator. In a 2002clinical study there was a 25-50% reduction in SIB episodesin all but one patient.

    UC Irvine has reported success with opiate-blockers such as

    Naltrexone. (There is a theory that these patient have aninability to feel normal pain.)

    Treament success depends on the patients unique brainchemistry.

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    Medications

    Atypical antipsychotics*,

    anticonvulsants/mood stabilizers*, SSRIs*,

    opiate antagonists, and beta blockers have all

    been used

    BUT there are No evidence based guidelines

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    Genetic causes of SIB

    Many forms of mental retardation are genetic,

    and in some disorders SIB is so predictable it is

    considered part of the disorder

    Examples are Lesch-Nyhan(metabolic

    syndrome), Prader-Willi, Smith-Magenis, de

    Lange, and Fragile X

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    Will not only encounter SIB in autistm

    or mental retardation

    Some adolescents may self-mutilate to take

    risks, rebel, reject their parents' values, state

    their individuality or merely be accepted.

    Patients may injure themselves out of

    desperation or anger to seek attention.

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    SIB can be a clue to psychological

    issues or serious psychiatric disease

    Hopelessness and worthlessness, or because they

    have suicidal thoughts. These children may suffer

    from serious psychiatric problems such as

    depression, psychosis, Posttraumatic StressDisorder (PTSD) and Bipolar Disorder.

    Children who have been abused or abandoned

    Some adolescents who engage in self-injury maydevelop Borderline Personality Disorder as adults.

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    Key to Treatment

    Pick up on the clues - what is driving the SIB?

    Combination of education, behavioral

    intervention/counseling, and medication

    For a PCP, the treatment approach is often

    rule out any medical causes or sources of pain,

    then referral to a psychologist(for behavioral

    therapy) or neurologist/psychiatrist(for med

    assessment)

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    What would you have done with the

    patient???

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    What happened with our patient

    Sent him for a complete medical workup (CBC,

    esr, crp, CMP, thyroid, UA, stool sample)

    Prescribed Valium as an emergent measure,

    until the medical workup was complete and

    we could consult with psychiatry about

    modifying his medication regimen.

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    References

    http://merrill.ku.edu/PDFfiles/selfinjurious%20behavior.pdf

    http://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Families

    Journal of Developmental & BehavioralPediatrics, Challenging Cases in Developmentaland Behavioral Pediatrics. April 2010

    Jounal of American Academy of Pediatrics,Gastrointestinal Disorders in Individuals withAutism Spectrum Disorders. Jan 2010

    http://merrill.ku.edu/PDFfiles/selfinjurious%20behavior.pdfhttp://merrill.ku.edu/PDFfiles/selfinjurious%20behavior.pdfhttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://aacap.org/page.ww?name=Self-Injury+in+Adolescents&section=Facts+for+Familieshttp://merrill.ku.edu/PDFfiles/selfinjurious%20behavior.pdfhttp://merrill.ku.edu/PDFfiles/selfinjurious%20behavior.pdfhttp://merrill.ku.edu/PDFfiles/selfinjurious%20behavior.pdf