Sanja Mirkov, BPharm, PGDipPH Clinical Quality Improvement Coordinator
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Course title INDUSTRIAL PHARMACY
Course Code PH701
Course Credit
Lecture : 3
Practical : 0
Tutorial : 0
Total : 3
Course Objectives
On the completion of the course, students will be able to:
Decide various instruments required in industrial manufacturing of solid, liquid and
parenteral preparation.
Understand technology transfer parameters and pilot plant scale up techniques.
Know various strategies for prevention of industrial hazards.
Know and understand need of QbD and PAT in pharmaceutical industry.
Detailed Syllabus
Sr. No.
Name of Chapter & Details Hours Allotted
Section-I
1 Human Resource Development:
Personal training, job specification, job enlargement and enrichment,
blue and white - collar jobs. Labor welfare
05
2
Preparation of qualitative and quantitative departmental layout with
equipments required for different dosage forms like solid, liquid and
semisolid dosage forms.
06
3
Technology transfer: Introduction, importance and process steps for
technology transfer, Reason for technology transfer, factors influencing
technology transfer, Barriers of technology transfer, Issues in technology
transfer.
Pilot plant & scale up technique.
09
4 Automation in Pharmaceutical Industry: Importance, Objective,
automation of tablet compression machine. 03
Section-II
5
Importance and Preparation of standard operative procedure (SOPs) for
equipments like rapid mixer granulator, tablet compression machine,
autoclave, dissolution apparatus and manufacturing or processing steps
like granulation, compression and tablet coating.
06
6
Industrial Hazards and Pollution Management:
Industrial safety management. Water pollution, water Pollution
abatement and effluent treatment, Air pollution, air pollution control
Devices, solid waste, Solid waste waste management, Noise Pollution,
Noise Abatement, Effluent Analysis and Treatment Methods, Effluent
Treatment in Formulation Plants, Effluent Treatment in Synthetic Drugs
Industry, Effluent Treatment in Fermentation Industry.
Industrial effluent treatment:
Physicochemical measurements of effluents, BOD, COD, Determination
of some contaminants. Effluent treatment procedure, treatment of some
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characteristic effluent.
Environmental considerations of packaging and recycling of packaging
materials along with national and international regulations.
7
QbD and PAT: Elements of QbD, QbD tools, significance of QbD, Design
of experiments –Methods and applications of optimization techniques to
assure quality in product, critical quality attributes, critical process, Process
analytical technology (PAT) in Pharmaceutical manufacturing. Goal of
PAT, Benefits of PAT, PAT tools, Process Analyser, Application of PAT in
chemical and pharmaceutical industry,
06
Instructional Method and Pedagogy:
Lectures will be conducted with the aid of multi-media projector, black board, OHP etc.
Assignments based on course content will be given to the students at the end of each
unit/topic and will be evaluated at regular interval.
Surprise tests/Quizzes/Seminar/Tutorials will be conducted.
Students Learning Outcomes:
At the end of the course the students will be able to:
Understand various strategies for prevention of industrial hazards.
Prepare standard operative procedure for equipments and manufacturing process.
Understand various critical steps involved in technology transfer.
Text Books:
1. Lachman “The theory and Practice of Industrial Pharmacy
2. Remingtons “Pharmaceutical Sciences”
3. Bentley’s Pharmaceutics.
4. Pilot plants model and scale-up methods, by Johnstone and Thring.
5. Pharmaceutical Process Validation by Loftus and Nash.
Reference Books:
1. J. F. Despautz: Automation and validation of information in pharmaceutical processing;
Marcel Dekker.
2. G. C. Cole: Pharmaceutical production facilities, Design and applications; Taylor and
Francis
Additional Resources
Soft copies of books title bearing Industrial Pharmacy operations are available on
http://www.pharmatext.org
Latest information regarding to Industrial Pharmacy updates are available on
http://www.pharmainfo.net
Course Title DOSAGE FORM DESIGN
Course Code PH702
Course Credit
Lecture : 3
Practical : 3
Tutorial : 0
Total : 6
Course Objectives
On the completion of the course, students will be able to:
Apply knowledge of excipients, preformulation studies, stability evaluation in the
formulation of pharmaceutical products and drug delivery systems.
To integrate aspects of preformulation, stability requirements, dissolution study, and
validation for the development of Pharmaceutical Dosage Forms.
Detailed Syllabus
Sr. No.
Name of Chapter & Details Hours Allotted
Section-I
1 Physico-chemical Characterization:
Study of physical properties of drug like physical form, particle size,
shape, density, crystallinity, hygroscopicity, wetting, dielectric constant,
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solubility, dissolution and organoleptic property and their effect on
formulation, stability and bioavailability. Rationale for selecting the
preferred polymorph/crystalline form.
Degradation Pathways:
Study of chemical properties of drugs like hydrolysis, oxidation,
reduction, polymorphisms, racemization, polymerization etc., and their
influence on formulation and stability of products.
Study of prodrugs in solving problems related to stability, bioavailability
and elegance of formulations.
Drug-excipient compatibility studies and its importance in
pharmaceutical development.
Traces of organic volatile impurities (OVIs) and their regulatory limits
(residual solvents).
2 Introduction to BCS and dissolution study:
Definition, Importance and objectives of dissolution, Dissolution
mechanisms, Factors affecting dissolution, Intrinsic dissolution rate
measurement, Dissolution apparatus for various dosage forms, Selection
of dissolution media and conditions, Dissolution profile comparison
methods, biowaiver.
Biological classification system (BCS); its significance on dissolution study
and application in dosage form development.
09
Section-II
3 Basics of IVIVR and IVIVC:
Methods of establishing IVIVC, Factors affecting IVIVC, Biorelevant
Dissolution Medium.
04
4 Stability of pharmaceuticals:
Kinetic principles and stability testing: Reaction rate and order, acid base
catalysis, decomposition reactions and stabilization of pharmaceuticals,
Effect of various environmental/ processing factors like light, pH,
temperature, etc. on stability of the formulation and techniques for
stabilization of product against the same, Stability of formulation, MKT,
climatic zones, matrixing and bracketing in stability study, accelerated
stability testing, real time stability. Current WHO, USFDA and stability
testing as per ICH guidelines for pharmaceutical drug substances and
drug products. Shelf-life, Overages, Overage calculations.
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5 Efffect of following adjavunts on formulation of different pharmaceutical
products: Antioxidants, preservatives, colours, flavours, diluents, binders,
disintigrants, antifictional agents, emulsifiers, suspending agents,
solvents etc. and other formulation additives.
06
Dosage Form Design (Practical)
1. Determination of the angle of repose, Carr’s index, Hausner’s ratio of given powder/
granules.
2. Determination of solubility of given drug at different pH.
3. To study the compression characteristic of different diluents.
4. To study the effect of various binders on performance of tablet.
5. To study the effect of various disintigrants on performance of tablet.
6. To study the Influence of temperature on the stability of aspirin/ ascorbic acid solution.
7. Compendial dissolution testing and data evaluation for given tablets and capsules.
8. In-vitro dissolution profile comparison of given tablet with reference product using
similarity and dissimilarity factor.
9. Enhancement of solubility of poorly water soluble drug by solid dispersion.
10. Enhancement of solubility of poorly water soluble drug by -Cyclodextrin complexation.
11. Preformulation studies including drug-excipient compatibility studies.
12. Calculation of bioavailability parameters from the given pattern of drug absorption from
oral & IV formulations.
13. Other practicals covering syllabus aspects.
Instructional Method and Pedagogy:
Lectures will be conducted with the aid of multi-media projector, black board, OHP etc.
Assignments based on course content will be given to the students at the end of each
unit/topic and will be evaluated at regular interval.
Surprise tests/Quizzes/Seminar/Tutorials will be conducted.
The course includes a laboratory, where students have an opportunity to build an
appreciation for the concepts being taught in lectures.
Students Learning Outcomes:
By the end of this course, the student should have a good understanding of basic process
which are used in different stage during preparation of pharmaceutical formulation.
Students should be able to know calculation of formulas, labeling, and packing of
different types of pharmaceutical products.
Text Books:
1. Pharmaceutical Dosage Forms and Drug Delivery Systems by Ansel & others.
2. Pharmaceutical Technology by Sambamurthy, New Age publication.
Reference Books:
1. The Science & Practice of Pharmacy: A. G. Remington; Lippincott, Philadelphia.
2. Pharmaceutical Dosage Forms: Tablets: Vol.1, Vol. 2 and Vol.3, Ed. by Lieberman, Leon
Lachman and Joseph B. Schwartz, Marcel Dekker Inc., New York.
3. Modern Pharmaceutics by Gilbert S. Banker and Christopher T. Rhodes, Marcel
Dekker, Inc., New York.
4. Stability of drug and dosage forms by Yoskioka, BSP publication.
5. Drug stability (Principles and Practices) by Jens. T. Carstensen, Marcel Dekker.
6. Pharmaceutical Preformulation by carstensen, CRC publication.
7. Pharmaceutical Dissolution Testing by Dressman and Jennifer, Informa publication.
8. Pharmaceutical dissolution testing by Umesh V. Banker, Marcel Dekker Inc.
Additional Resources
Soft copies of dosage form design books are available on http://www.pharmatext.org,
www.pharmacyebooks.com, and in www.pharmamirror.com.
Latest information regarding dosage form design are available on
http://www.pharmainfo.net
Study material of dosage form design are available on mypharmaguide.com,
pharmatutor.com, authorstream.com, slideworld.com and in scribd.com .
Review articles published in international journal covering syllabus aspect.
Course Title MEDICINAL CHEMISTRY- III
Course Code PH703
Course Credit
Lecture : 3
Practical : 3
Tutorial : 0
Total : 6
Course Objectives
Medicinal chemistry-III will provide the sound knowledge about basic principles of medicinal
chemistry like development of various drugs on various basis, nature and property of various
classes of drugs including Central nervous system, Hormonal drugs like steroids, anti-diabetic,
anti-thyroid, thyroid and drugs affecting immune system of body. Also the students will learn
chemistry, stereochemistry, nomenclature and application of all the steroids and related
hormonal drugs used in various wide spread disease. To know and learn about some specific
disorders related to CNS and drug therapy in the same.
Detailed Syllabus - Theory
Sr.
No. Name of Chapter & Details
Hours
Allotted
Section-I
1 Drugs Acting on CNS:
A. CNS stimulants:
Analeptics, Antidepressants, hallucinogens
SAR:- Tri-cyclic antidepressants
Synthesis of Amphetamine, Nikethamine, Fluoxetine, Imipramine,
Amitriptylline
B. CNS Depressants:
General and local anesthetics, Sedative and hypnotics, Anxiolytics,
Antiepileptics, Antipsychotics
SAR:- Benzoic acid and Anniline derivatives with Local anesthetic activity,
Barbiturates, Benzodiazepines, Phenothiazines, Butyrophenones
Synthesis of Halothane, Lignocaine, Procaine, Benzocaine, Thiopental
sodium, Phenobarbitone, Chlordiazepoxide, Meprobamate, Phenytoin,
Sodium valproic acid, Ethosuximide, Carbamazepine, Chlopromazine,
Trifluperazine
C. Opiod Analgesics and Non-Opiod Analgesics;
SAR:- Morphine, Pethidine, Benzomorphan, Morphinan
Synthesis of Pethidine, Methadone
D. Non Steroidal Anti-Inflammatory Agents, Anti Gout and DMARDS:
Synthesis of Paracetamol, Aspirin, Diclofenac, Ibuprofen, Indomethacin,
Allopurinol, Mefenamic acid, Nimesulide, Naproxen
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Section-II
2 Hormones and Related drugs:
A. Antidiabetic agents:
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Synthesis of Glipizide, Metformin, Pioglitazone, Tolbutamide,Glimipride.
B. Thyroid Hormones and Antithyroid Drugs
Synthesis of Thyroxine, Methimazole, Carbimazole.
C. Steroids and Therapeutically related compounds
(i) Nomenclature and stereochemistry of steroids
(ii) Adrenocorticoids – Mineralocorticoids, Glucocorticoids
(iii) Estrogens, Progestins and Androgens
SAR: Estrogens and Adrenocorticoids, Progestins, Androgens
3 Immunomodulators 02
4 Diagnostic agents:
Radiopharmaceuticals, Radiological contrast media (diphenoxylate,
diatrizoic acid, sodium iothalamate)
02
5 Drugs used in Neurodegenerative diseases
Alzheimer’s disease, Cognition enhancers, Parkinsonism
03
6 Drugs acting on uterine motility: oxyticics 02
Medicinal chemistry- III (Practicals)
To study different techniques available for synthesis at the laboratory scale
To check different parameters of synthesized product.
To purity synthesized product by re-crystallisation or distillation or column chromato
graphy if applicable
Thoroughly study in depth about the mechanism or type of reaction involved behind
formation of every product
synthesis of following compounds are to be performed,
A. Synthesis involving types of rearrangements:
1) Benzil-benzilic acid rearrangement: Synthesis of benzilic acid
2) Bamberger rearrangement : Synthesis m-nitro phenol
B. Synthesis of heterocyclic rings (substituted/unsubstituted):
1) Pachmann condensation reaction: Synthesis of 7-hydroxy 4- methyl coumarin
2) Synthesis of benzimidazole
C. Synthesis of drug molecules:
1) Synthesis of paracetamol
2) Haloform reaction: Synthesis of Iodoform
D. Synthesis of dye substance:
1) Synthesis of methyl orange
Students Learning Outcomes:
1. Know the basic concepts of medicinal chemistry from practical and theoretical both
aspect, its scope and various branches.
2. To identify pharmacophoric binding sites in drug responsible to bind with receptor
3. To study about which methods to apply for purification for different synthesized crude
product
4. To study about chemistry of individual drug molecule.
5. To study about drug interactions and adverse effects.
6. To study in detail about the SAR (structure activity relationship) of different classes of
drugs.
7. Know about the development of new drug.
Text Books:
1. Foe’s principles of medicinal chemistry. David A. Williams & Thomas L. Lemke. Lippincott
Williams & Wilkins.
2. Wilson and Griswold’s textbook of organic medicinal and Pharmaceutical Chemistry,
John H. Block and John M. Beale, Jr.. Lippincott Williams & Wilkins.
Reference Books:
1. Harkishan Singh and V.K Kapoor – text book of medicinal chemistry.
2. Medicinal chemistry by ashutoshkar
3. Principles of medicinal chemistry by kadam and bothara
4. Experimental organic and medicinal chemistry by biren n., shah. S. vikas.
5. Practical organic chemistry, Hitesh G. Raval, Sunil L. Baldania, Dimal A. Shah, Nirav and
Roopal Prakashan.
6. Burger’s Medicinal Chemistry and Drug Discovery, Donald j Abraham, Wiley interscience.
7. Vogel’s text book of practical organic chemistry.
8. Practical organic chemistry by F.G Mann and Saundars
Additional Resources
Soft copies of important topics to be covered.
Collect and share latest informations available from scientific journals available on e-library
and on websites.
Seminars and oral presentation on some specific topic
Course Title INSTRUMENTAL ANALYSIS-II
Course Code PH704
Course Credit
Lecture : 3
Practical : 3
Tutorial : 0
Total : 6
Course Objectives
On the completion of the course, students will be able to:
1. Understand the fundamental concepts of chromatography and other analytical method.
2. Understand the principle, instrument theory and practical, effect and application of
various chromatography method like HPLC, GC and HPTLC,
3. Understand the concept of ISO, GLP and validation method
Detailed Syllabus
Sr. No.
Name of Chapter & Details Hours Allotted
Section-I
1 X-ray spectroscopy
Introduction; Generation of X – rays; X-ray diffraction, Bragg’s law;
Applications of X- ray diffraction
04
2 Overview of Scattering Spectroscopy like Raman spectroscopy,
Nephlometry and turbidimetry.
03
3 Gas Chromatography
Introduction; Theory and Principle of Gas-Chromatography; Mobile
phase, Stationary phases for GSC and GLC; Instrumentation (including
temperature programming and derivatization) and applications of GC;
Overview of GC-MS.
06
4 Basic principle, theory and applications of partition, adsorption, ion-
exchange, size exclusion, Super critical fluid, Affinity chromatography
06
5 Atomic spectroscopy
Basics of atomic spectroscopy; Principle of atomic absorption and atomic
emission spectroscopy; Interferences in atomic spectroscopy; Factors
affecting atomic spectroscopy like solvents, buffers, other ions, etc;
Flame Photometry; Atomic emission spectroscopy with plasma and
electrical discharge sources; Instrumentation ( including radiation
sources like hollow cathode lamp ), applications, advantages and
limitations of atomic absorption and atomic emission spectroscopy.
05
Section-II
6 High Performance Liquid Chromatography
Introduction; Theory, Classification and Principle of HPLC; Mobile phase,
Stationary phases for normal and reversed phase HPLC; Instrumentation
and applications of HPLC; Comparison of HPLC with GC; Overview of LC-
MS, LC-MS/MS.
UPLC : Introduction, instrumentation and application
12
7 HPTLC
Principle; Comparison with HPLC; Instrumentation, applications,
advantages and limitations of HPTLC.
03
8 Radiochemical methods
Introduction; Nuclear reactions and radiation; Interaction of nuclear
radiation with matter; Radioactive decay; Units of radioactive decay;
Measurement of radioactivity; Activity analysis; Isotopes dilution
analyses; Liquid scintillation systems; Applications of radio nuclides
04
9 Overview of radio-immuno assay (RIA) and ELISA (Immunochemical
techniques).
03
Instrumental analysis II (Practical)
1. Separation and identification of drugs/impurities/related substances by TLC methods as
per I.P.(Three experiments)
2. Separation and identification of amino acids/flavonoids/sulphonamides by paper
chromatography. (min. one experiment)
3. Quantitative analysis of market formulations by HPLC. (Two experiments including
Formulation)
4. Potentiometric assay of any two formulations from I.P. (e.g. Sulpha drug, INH, penicillins)
5. Assay of dextrose injection by polarimetry
6. Assay of drugs by aqueous & non-aqueous pH-metry titration. (Two experiments)
7. Simultaneous estimation of Paracetamol & Ibuprofen/any other combination
8. Flame photometric estimation of sodium/potassium ions in urine/ORS.
Instructional Method and Pedagogy:
Lectures will be conducted with the aid of multi-media projector, black board, OHP etc.
Assignments based on course content will be given to the students at the end of each
unit/topic and will be evaluated at regular interval.
Surprise tests/Quizzes/Seminar/Tutorials will be conducted.
The course includes language practices such as Group Discussion, Interviews etc to
develop the communication skills of the students.
Students Learning Outcomes:
At the end of the course the students will be able to:
1. Operate the different sophisticated instrument which used in industry level at various
analytical purpose
2. Understand the basic principle of chromatography and their application
Text Books:
1. Principles of Instrumental Analysis by skoog, holler, Nieman, 5th edition.
2. Instrumental methods of Analysis, H.H. Willard, L.L. Meritt, J.A. Dean and F.A. Settle
Wadsworath, New York
Reference Books:
9. Pharmaceutical Analysis: Modern methods Part A, Part B, James W. Munson.
10. Quality Assurance of Pharmaceuticals – A compendium of guidelines and related
materials – Vol. I – WHO Publications.
11. IPR Handbook for Pharma Students and researchers – Parikshit Bansal, Pharma Book
Syndicate, Hyderabad
12. Pharmacopoeia of India, Govt. of India, Ministry of Health.
13. British Pharmacopoeia, ministry of health and social welfare, UK.
14. The United States Pharmacopeia–National Formulary (USP–NF)
Additional Resources
Soft copies instrument analysis books are available on http://www.pharmatext.org
Latest information regarding to instrument analysis are available on
http://www.pharmainfo.net
Course Title CLINICAL PHARMACY - I
Course Code PH705
Course Credit
Lecture : 3
Practical : 0
Total : 3
Course Objectives
Clinical Pharmacy I will provide the basic knowledge on scope and development of clinical
pharmacy, health care team and basic functions of clinical pharmacist. It will provide basic
importance of recording medication history, ward round participation, avoiding self
medication, developing communication skills and improving patient counseling,
therapeutic drug monitoring, and concepts of essential and rational drugs. It also includes
selection of drugs in special group of populations like geriatric, pediatric and in pregnancy.
It will provide the implementation and application of various laboratory tests in diagnosis
of specific diseases. It will provide a sound knowledge on selection of correct drug for
diseases of respiratory, GIT, endocrine, gout, obesity and glaucoma. It will also provide a
knowledge on Pharmacoeconomics and pharmacoepidemilogy.
Detailed Syllabus
Sr. No.
Name of Chapter & Details Hours Allotted
Section-I
1 Development and scope of clinical pharmacy, concept of health care
team, Role and functions of clinical pharmacist as a member of health
care team
02
2 Basic concepts of Clinical Pharmacy
Recording of medication history, Ward round participation, self
medication, nonprescription drug usage, improving patient compliance
and providing patient counseling, Communication skills- Behavioral and
interpersonal, with patients and other professionals.
05
3 Principles of Drug therapy and management of diseases in special
population
Pediatrics, Geriatrics and Pregnant Women
06
4 Interpretation of clinical laboratory tests, as markers of major organ
damage and their effect on drug therapy decisions
a. Hematological, Liver function, Renal function and thyroid function
tests
b. Tests associated with cardiac disorders
c. Tests for Diabetes Mellitus
d. Fluid and Electrolyte Imbalance
e. Microbiological culture sensitivity tests
f. Pulmonary Function Tests
07
5 Concepts of Essential drugs and Rational Drug use 02
6 Therapeutic Drug Monitoring 01
Section-II
7 Management of diseases and medication related problems; and
decision making processes including utilization of laboratory tests to
monitor drug efficacy and toxicity.
a. Respiratory: Bronchial asthma, COPD
b. Gastrointestinal: Peptic Ulcer Disease, Inflammatory Bowel Disease,
Hepatitis
c. Endocrine: Diabetes mellitus, Thyroid disorders, Parathyroid
disorders, Osteoporosis, Hormone Replacement Therapy
d. Rheumatoid arthritis and gout
e. Obesity
f. Glaucoma
19
8 Pharmacoeconomics and Pharmacoepidemiology 03
Instructional Method and Pedagogy:
Lectures will be conducted with the aid of multi-media projector, black board, OHP etc.
Assignments based on course content will be given to the students at the end of each
unit/topic and will be evaluated at regular interval.
Surprise tests/Quizzes/Seminar/Tutorials will be conducted.
The course includes language practices such as Group Discussion, Interviews etc to
develop the communication skills of the students.
Students Learning Outcomes:
8. Know the basic concepts of clinical pharmacy, its scope and role of clinical pharmacist
in various areas.
9. Select the correct drug for disease with suitable dose, route of administration and
formulation along with necessary precautions.
10. Know the importance of proper selection of drug otherwise resulting in drug
interactions and adverse drug reactions.
11. Know the principle concepts of drug selection in management of diseases in special
group of patients like pediatric, geriatric and pregnant women
12. Know the importance of therapeutic drug monitoring and application of essential and
rational drug use concept.
13. Know about management of diseases of respiratory, GIT, endocrine, gout, obesity and
glaucoma with the use of diagnostic procedures.
14. Know about the importance and application of Pharmacoeconomics and
Pharmacoepidemiology.
Text Books:
9. Clinical Pharmacy and Therapeutics. Roger Walker and Clive Edwards, Churchill
Livingstone Edinburgh / London.
10. Text Book of Therapeutics: Drug and Disease Management. 8th Ed. Editors: Eric
T.Herfindal and Dick R. Gurley, Williams and Wilkins, 2006.
11. A text book of Clinical Pharmacy Practice (Essential concepts and skills). G.
Parthasarhi, Karin Nyfort-Hansen & Milap C Nahata. University Press impression, 2008
Reference Books:
1. Pharmacotherapy: A Pathophysiological Approach. J. T. Dipiro, R. L. Talbert etal,
McGraw-Hill, New York.
2. Pathology & Therapeutics for Pharmacists. Russell J. Greene and Norman F. Harris
3. Davidson’s Principle and Practice of Medicine, Eds. Christopher R.W. Edwards & Ian
A.D. Boucher ELBS with Churchill Livingstone, Edinburgh.
4. Applied Therapeutics: The Clinical Use of Drugs Eds. Brian S. Katcher, Lloyd YeeYoung,
Marry Anne Koda-Kimble, Applied Therapeutics Inc.
5. Melmon and Morrelli’s Clinical Pharmacology, 4th Edition. Authors: S. George
Carrathers, Brian B. Hoffman, Kenneth L. Melmon and David W. Nierenberg. McGraw
Hill, 2000.
6. Principles of Pharmacology – Paul L. Munson
7. Lewis’s Pharmacology – James Crossland – Churchil Livingstone
8. Modern Pharmacology with clinical applications- Craig, Charles R.
Additional Resources
Soft copies of pharmacology and pathophysiology books are available on websites.
Latest informations are available from scientific journals available in library and on
websites.
Course Title TRADITIONAL DRUGS AND SYSTEMS OF MEDICINE
Course Code PH706
Course Credit
Lecture : 3
Practical : 3
Tutorial : 0
Total : 6
Course Objectives
On the completion of the course, students will be able to:
Understand the various aspects of traditional systems of medicines with special reference to
Ayurvedic system of medicines.
Understand various aspects of crude drugs belong to traditional systems of medicines.
Understand an importance of traditional drugs.
Detailed Syllabus
Sr. No.
Name of Chapter & Details Hours
Allotted
Section-I
1 Introduction to Ayurveda and other traditional systems of medicine. 05
2 Study of the following traditional drugs, their vernacular names, biological
sources, cultivation, collection, commercial varieties, official varieties, chemical
constituents, substitutes, adulterants, common and ethnomedicinal uses,
trade, research and formulations: Harde, Baheda, Amla, Arjun, Ashok,
Shatavari, Ashwagandha, Tulsi, Damvel, Kalijiri, Nagod, Rasna, Punarnava,
Chitrak and Apamarg.
15
Section-II
3 Study of the following traditional drugs, their vernacular names, biological
sources, cultivation, collection, commercial varieties, official varieties, chemical
constituents, substitutes, adulterants, common and ethnomedicinal uses,
trade, research and formulations: Gokhru, Shankhapusphi, Brahmi, Ardusi,
Methi, Palash, Guggul, Gudmaar, Garmalo, Shilajit, Neem, Lahsun, Majith,
Chakramadu, Galo, Malkangni, Karanj, Pipar, Chirata, Kalmegh, Bhringraj, Hing,
Adrakh, Haldi and Vaj.
25
Traditional Drugs And Systems Of Medicine (Practical)
1. Morphological and Microscopical study of traditional drugs.
2. Comparison of various species, especially controversial drugs.
3. Identification of medicinal plants and crude drugs.
Instructional Method and Pedagogy:
Lectures will be conducted with the aid of multi-media projector, black board, OHP etc.
Assignments based on course content will be given to the students at the end of each
unit/topic and will be evaluated at regular interval.
Surprise tests/Quizzes/Seminar/Tutorials will be conducted which carries 5% component of
the overall evaluation.
The course includes language practices such as Group Discussion, Interviews etc to develop
the communication skills of the students.
Students Learning Outcomes:
At the end of the course the students will be able to:
Understand various basic concepts of Ayurvedic and other traditional systems of medicines.
Understand importance of Ayurvedic systems of medicines and crude drugs belongs to it.
Text books:
1. Shah and Qadry’s Pharmacognosy: J. S. Qadry, 14th edition, B S Shah Prakashan, Ahmedabad.
Reference Books:
1. The Wealth of India, Publications and Information Directorate, CSIR, Hillside road, New
Delhi.
2. Indian medicinal plants, K. R. Kirtikar & B. D. Basu, Vol. 1, 2nd ed., 2005, International Book
Distributor, Dehradun, India.
3. Indian medicinal plants, C. P. Khare, 2007, Springer Verlag Berlin.
4. Ayurvedic Pharmacopoeia of India (latest edition)
5. Ayurvedic Formulary of India (latest edition)
6. Indian Pharmacopoeia – Vol. III (latest edition)
Additional Resources:
www.ayushveda.com
www.ayurveda-foryou.com