Subs%tucin Electro1lica Arom%ca (SEAr)

What Is Coal?

Nomenclature of Benzene Deriva%ves

Polysubs%tuted Deriva%ves of Benzene

1. Iden%fy and name the parent. 2. Iden%fy and name the subs%tuents. 3. Assign a locant to each subs%tuent. 4. Arrange the subs%tuents alphabe%cally.

Structure of Benzene

A. Kekul (1866)

Stability of Benzene

The Criteria for Aroma%city

1. The compound must contain a ring comprised of con%nuously overlapping p orbitals. 2. The number of electrons in the ring must be a Hckel number.

Aroma%c Heterocycles

Reac%ons at the Benzylic Posi%on

Electrophilic Aroma%c Subs%tu%on

Mecanismo general

Halogena%on

Sulfona%on

Nitra%on

Friedel-CraZs Alkyla%on

Friedel-CraZs Acyla%on

Clemmensen reduc%on