Screening Log Print this Form Not Started - UAB

© 2017 PHTS [PHTS]

Screening Log Not Started Print this Form

Center Code

Patient Initials If middle initial is not known, enter a hyphen (-)

1 Is patient under the ageof 18 at the time of listing?

If the patient is 18 years of age or older at the time of listing, they are not eligible for PHTS.

No Yes

2 Was informed consent andHIPAA Authorization obtained?

No Yes/my center has a waiver

3 Was the patient listed for a heart/lung transplant?

Heart/lung listings are not currently eligible for PHTS. All other simultaneous organ listings are eligible.

Yes No

4 Is this the patient’s first listing for a heart transplant?

No Yes

5 Is this a Japanese-American transfer patient?

Yes No

5a Are they coming from Japan or North America?

Japan North America

5a.i Enter patient ID from North American

Hospital

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Patient Details Hidden ShowShow/Hide Annotations

Demographics Not Started Print this Form

1 Date of Birth MM/DD/YYYY

2 Sex Female

Male

3 Race Check all that apply.

African-American or Black

American Indian or Alaskan Native

Asian

Hawaiian or other Pacific Islander

Unknown/Undisclosed

White

Other, specify

4 Hispanic or Latino Yes if of Mexican, Puerto Rican, Cuban, Central

or South American or other Spanish

culture of origin, regardless of race.

No

Yes

Unknown

5 Primary Etiology Cardiac Tumor

Cardiomyopathy

Congenital Heart Disease

Myocarditis

Other, specify

5a Cardiomyopathy ARVD/C

Dilated

Hypertrophic

MIXED

Restrictive

Unknown

Other, specify

5a.i Cardiomyopathy: Dilated

Chemotherapy-Induced

Conduction Defect

Familial

Ischemic

Isolated/Idiopathic

LVNC

Metabolic/Syndromic/Mitochondrial

Neuromuscular

s/p Myocarditis

Page 1 of 3PHTS - Demographics

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Unknown

Other, specify

5a.i.1 Cardiomyopathy: Dilated, Ischemic

ALCAPA

Kawasaki

Unknown

Other, specify

5a.ii Cardiomyopathy: Hypertrophic

Familial

Isolated/Idiopathic


Neuromuscular

Unknown

Other, specify

5a.iii Cardiomyopathy: Restrictive

Chemotherapy-Induced

Isolated/Idiopathic

LVNC


s/p Radiation

Unknown

Other, specify

5b Congenital Heart Disease ASD/VSD

Complete AV Septal Defect/AV Canal

Cong. Corrected Trans. (I-TGA) (CC-TGA)

Coronary Anomaly

Double Inlet Left Ventricle

Ebstein's Anomaly

Hypoplastic Left Heart

Hypoplastic Right Heart

Left Heart Valve/Structural Hypoplasia

Left Ventricular Outflow Tract Obstruction

No additional diagnosis other than Single Ventricle

PAPVR

Pulmonary Atresia with IVS

Right Heart Valve/Structural Hypoplasia

TAPVR

TOF/TOF Variant/DORV/RVOTO

Transposition of the Great Arteries (d-TGA)

Tricuspid Atresia

Truncus Arteriosus

Unknown

Other, specify



© 2017 PHTS [PHTS]

5b.i Single Ventricle No

Yes

Unknown

5b.ii If pulmonary atresia with IVS,

RV dependent coronary circulation

No

Yes

Unknown

6 Blood Type A

AB

B

O

Unknown

6a Blood A Subtype A1

A2

Unknown

7 Rh Negative

Positive

Unknown



Calculated

BSA: n/aBMI: n/a


Height and Weight

Surgeries Prior to Listing

Form 1: Listing Not Started Print this Form

1 Listing Date MM/DD/YYYY

2 Height Centimeters Inches

Missing Reason: Not DoneUnknown

3 Weight Kilograms Pounds


4 Main reason for listing Select only one primary reason for listing.

CHD too high risk for palliative surgical options

Growth failure due to the heart disease

Hypercyanosis without further palliative surgical options

Malignant arrhythmia

Medically refractory heart failure

Plastic bronchitis

Progressive liver disease

Progressive pulmonary hypertension

Protein losing enteropathy

Unknown

Other, specify

4a Medically refractory heart failure

Both

Diastolic Failure

Systolic Failure

Unknown

5 Did the patient have any cardiac surgery prior to listing?

No

Yes

Unknown

Page 1 of 14PHTS - Form 1: Listing

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Surgery Details

5 If Congenital cardiac surgery, specify surgery:

AP Shunt

Arterial switch operation

ASD Repair

Atrial switch (Senning/Mustard)

CABG

Complete AV Septal Defect Repair

Congenitally Corrected Transposition Repair (classic) Congenitally Corrected Transposition Repair (double switch)

Damus Kaye Stansel (DKS)

d-Transposition of the Great Vessels Repair

Ebstein's Anomaly Repair

Fontan Procedure

Glenn Procedure

Hybrid Palliation

Norwood Stage I: BT Shunt

Norwood Stage I: Sano/RV-PA conduit

PA Banding

TOF/DORV/RVOTO Repair

Truncus Arteriosus Repair

Valve Replacement

VSD Repair

Other, specify

5 Date of Surgery Missing Reason: Unknown

5 Congenital cardiac surgery, d- Transposition of the Great

Vessels Repair

Arterial Switch Operation

Atrial Switch (Senning/Mustard)

5 Congenital cardiac surgery, Valve Replacement

Aortic Valve Replacement

Mitral Valve Replacement

Pulmonary Valve Replacement

Tricuspid Valve Replacement

Other, specify

5 Homograft Tissue in Aortic Valve Replacement?

Yes

No

Unknown

5 Pulmonary valve replacement?

Yes

No

Unknown



Status Details at Listing

6a Status at Listing Brazil

Canada

United Kingdom

United States

6a.iv Status at Listing, US 1 (this option is only for listings prior to 1999)

1A

1B

2

7

6a.ii Canada 1

2

3

3.5

4

4S

6a.iii United Kingdom Routine

Urgent

6a.i Brazil Non-Priority

Priority

6b Was patient in or out of hospital at time of listing?

In hospital

Out of hospital

6b.i Was patient in the ICU at time of listing?

No

Yes

Unknown

6b.ii Did the patient require continuous invasive

mechanical ventilation?

No

Yes

Unknown

6c Did the patient require continuous inotropes at time of listing?

Yes

No

Unknown

6c.i Inotropes Dose Dose Unknown

High Dose or Multiple IV

Single Low Dose



Infectious Disease Screening

6d Did the patient have ductal dependent pulmonary or

systemic circulation, with ductal patency maintained by stent or

prostaglandin infusion?

Yes

No

Unknown

6e Was patient listed for ABO Incompatible?

No

Yes

Unknown

6f Was patient on a VAD or ECMO at time of listing?

VAD

ECMO

Not on support at time of listing

6f.i Specify initiation date (VAD) Missing Reason: Unknown

6f.ii Specify initiation date (ECMO)

Missing Reason: Unknown

6g Was patient listed for DCD (Donation after Cardiac Death)

organ?

Yes

No

Unknown

This is not current practice at our center

Not Applicable

7a 7a HIV Serology AIDS testing

Negative Not Done Positive Unknown

7b CMV Serology Negative Not Done Positive Unknown

7c CMV PCR Negative Not Done Positive Unknown

7d EBV Serology Negative Not Done Positive Unknown

7e EBV PCR Negative Not Done Positive Unknown

7f IFA Toxo Toxoplasma testing


7g HBs Ag Hepatitis B surface antigen


7h HB core Ab Hepatitis B core antibody


7i HBs Ab Hepatitis B surface antibody




Medical History at time of Listing

7j Hep C Ab Hepatitis C antibody


7k RPR/Syphilis Syphilis testing


8 Medical History No

Yes

Unknown

8a Type of medical history at Listing

Arrythmia

Cardiac Arrest/CPR

Diabetes

GI/Nutrition

Heterotaxy/Isomerism

Malignancy

Metabolic/Disorder

Mitochondrial Disorder

Neurologic

Pacemaker

Peripheral Myopathy/Neuromuscular disease

Prenatal Diagnosis

Prior Transfusions

Renal Insufficiency

Respiratory

Shock

Syndrome

Other, specify

8a.i Arrhythmia Afib/flutter

Complete heart block

V Fibrillation

V Tachycardia

Unknown

Other, specify

8a.ii Cardiac arrest/CPR Date

MM/DD/YYYY


8a.x Pacemaker Defibrilliator/AICD

Pacemaker, CRT/biventricular pacing

Pacemaker, not CRT and not ICD

8a.x.3 Pacemaker,not CRT




and not ICD,Date Placed

MM/DD/YYYY

8a.x.2 Pacemaker,

CRT/biventricular pacing, Date Placed

MM/DD/YYYY


8a.x.1 Pacemaker,

Defibrillator/AICD Date Placed

MM/DD/YYYY


8a.xiv Shock, Date of last appropriate

Shock MM/DD/YYYY


8a.iii Diabetes, Date of last Hgb

A1c MM/DD/YYYY


8a.iii Diabetes, Value of last Hgb

A1c


8a.iii Diabetes, Treating with

insulin

No

Yes

Unknown

8a.iv Medical History, GI/Nutrition

Failure to thrive/cachexia

Fontan associated liver disease

Infectious hepatitis

Protein losing Enteropathy

Other, specify

8a.iv.1 GI/Nutrition,

Infectious hepatitis type

A

B

C

Unknown

Other, specify

8a.v Medical History,


Asplenia

Polysplenia

Unspecified



Other, specify

8a.vi Medical History, Malignancy

Lymphoma, leukemia

s/p BMT

s/p Chest Radiation

Solid organ cancer

Unknown

Other, specify

8a.ix Medical History, Neurologic

Anoxic brain injury

Hemorrhagic and/or thromboembolic stroke

Other, specify

8a.ix.1 Neurologic,

Anoxic brain injury Last Date MM/DD/YYYY


8a.ix.2 Neurologic,


Date Last MM/DD/YYYY


8a.xi Medical History, Peripheral

myopathy/neuromuscular disease

Becker MuscularDystrophy

Duschenne Muscular Dystrophy

Freidrich's Ataxia

Unspecified

Other, specify

8a.xiii Medical History, Respiratory

Asthma

Plastic Bronchitis

Tracheostomy

Unknown

Other, specify

8a.xii History Dialysis Dialysis, acute (within past 30 days)

Dialysis, chronic (>1 month duration)

Dysfunction, not dialysis

Unknown

Other, specify



Insurance

• Charitable Donation – Indicates that a company, institution or individual(s) donated funds to pay for the care of the listed patient.

• Free – Indicates that the listing hospital will not charge the patient for the cost of the hospitalization

• Government – Other US or state government insurance. For Example, Medicaid, Medicare, CHIP (Children’s Health Insurance Program), Department of VA refers to funds from the Veterans Administration or others.

• Private – Refers to funds from agencies such as Blue Cross/Blue Shield, etc.• Self Pay – Indicates that the recipient will pay for the largest portion of the cost

of the hospitalization.• Other – For example, funds from a foreign government. Specify foreign country

in the space provided.

Percent or Panel Reactive Antibody (closest to listing)

8a.xv Medical History, Syndrome

Cardiofaciocutaneous Syndrome

Costello Syndrome

Digeorge (22q11 deletion)

Down's/Trisomy 21

Ehlers-Danlos Syndrome

LEOPARD/Multiple Lentigenes

Loeys-Dietz Syndrome

Marfan Syndrome

Noonan Syndrome

Other Marfan-like Syndrome

Turner Syndrome

Unspecified

Williams Syndrome

Other, specify

8a.vii Specify Metabolic Disorder

8a.viii Medical History, Mitochondrial

Disorder, specify

Barth's

Unspecified

Other, specify

9 Primary Insurance Charitable Donation

Free

Government

Private

Self Pay

Unknown

Other, Specify



10a Cytotoxic PRA ie. Serum is tested against panel of lymphocytes

Done

Not Done

10a.i T Cell % Missing Reason: Not DoneUnknown

10a.ii B Cell % Missing Reason: Not DoneUnknown

10a.iii Date (Cytotoxic PRA) Missing Reason: Unknown

10b Cytotoxic PRA, DTE/DTT Panel performed on serum treated with DTE or DTT (or

equivalent)

to reduce the IgM antibodies and identify high PRA results

presumably secondary to a drug or other causes.

Done

Not Done

10b.i T Cell % Missing Reason: Unknown

10b.ii B Cell % Missing Reason: Unknown

10b.iii Date (Cytotoxic PRA, DTE/DTT)


10c Flow Cytometry or Luminex PRA

Done

Not Done

10c.i Class I % Missing Reason: Unknown

10c.ii Class II % Missing Reason: Unknown

10c.iii Date MM/DD/YYYY


10d Listed for prospective crossmatch

No

Yes

Unknown

10d.i Prospective Crossmatch Results

Donor Cells

Donor Cells and Virtual

Virtual

Unknown



Hemodynamics Prior to ListingIndicate the hemodynamics even if the patient is on pressors or inotropes. Best hemodynamics are those performed during the administration of agents given specifically to lower the pulmonary arterial pressure or the pulmonary vascular resistance. All pressures should be listed in mmHg. If unclear, please consult with your PI.

10d.i.1 Virtual Crossmatch

Avoidance of donor antigens to all antibodies present Avoidance of donor antigens to antibodies above pre-specified threshold Avoidance of donor antigens to C1q fixing antibodies only

Unknown

11 Were hemodynamics done prior to listing?

No

Yes

Unknown

11a Date MM/DD/YYYY


11b Fontan Mean Pressure Missing Reason: Not DoneUnknown

11c RAm (RAP or CVP) Right Atrial Mean Pressure


11d PAm Pulmonary Artery Mean


11e PCW Mean Pulmonary Capillary Wedge Pressure


11f SVC Sat Oxygen Saturation in the SVC


11g AO Sat Aortic Saturation


11h Rp, PVRI Pulmonary resistance indexed to body surface

area (BSA)

Woods Units x m2

wu x m2 Missing Reason: Not DoneUnknown

11i Rs, SVRI Systemic resistance indexed to body surface area

(BSA)

Woods Units x m2




Schooling

11j EDP End diastolic pressure of systemic ventricle


11k C.O. Cardiac output (i.e. Qs) in L/min

L/min Missing Reason: Not DoneUnknown

11l C.I. Cardiac index (i.e. C.O. divided by m2) in L/min/m2

L/min/m2 Missing Reason: Not DoneUnknown

11m Was patient on mechanical support

at time of Hemodynamics

No

Yes

Unknown

11n Hemodynamic Agents Used

No

Yes

Unknown

11n.i Indicate agent for best

hemodynamics

100% O2

Dobutamine

Dopamine

Epinephrine

Isoproterenol (Isuprel)

Milrinone (Primacor)

Nesiritide

Nitric Oxide

Nitroglycerin

Nitroprusside (Nipride)

Norepinephrine

PGE (Alprostadil)

PGI (Flolan)

Phenylephrine/ Neosynephrine

Sildenafil

Vasopressin

Unknown

Other, specify

12 Is the patient in school? No

Not Applicable, <6 years

Yes

Unknown

12a Are they at the age appropiate level

No

Yes



Exercise Test

Laboratory Values closest to time of this reportNote: labs may have been collected on different dates.

Unknown

12b Are they in a special education class

No

Yes

Unknown

13 Was exercise test performed? No

Yes

Unknown

13a If exercise test not performed,

specify reason

Age inappropriate

Too sick

Unknown

Other, specify

13b Max VO2% Predicted for Age

Refers to predicted maximum VO2 for patient

(should be listed in exercise report; if not,

exercise lab personnel should be able to provide this data)

% Missing Reason: UnknownNot Done

13c Max VO2Maximum oxygen consumption

ml/kg/min Missing Reason: UnknownNot Done

13d Respiratory Value at Peak RER or Respiratory Quotient:R Value at peak is

the respiratory quotient

of carbon dioxide production divided by oxygen consumption,

and is used as an index of how vigorously the patient exercised.

A value above 1.05 is generally considered to represent an adequate

effort.

Missing Reason: UnknownNot Done

14a Total Bilirubin mg/dL Missing Reason: Not DoneUnknown

14b Direct Bilirubin mg/dL Missing Reason: Not DoneUnknown

14c AST Aspartate transaminase (also SGOT)

U/L Missing Reason: Not DoneUnknown



14d ALT Alanine transaminase (also SGPT)


14e BNP B-type natriuretic peptide

pg/mL or ng/L Missing Reason: Not DoneUnknown

14f Pro BNP Pro NT B-type natriuretic peptide


14g CRP C reactive protein

mg/dL Missing Reason: Not DoneUnknown

14h Creatinine mg/dL Missing Reason: Not DoneUnknown

14i BUN Blood urea nitrogen


14j Cystatin C mg/L Missing Reason: Not DoneUnknown

14k Total Protein g/dL Missing Reason: Not DoneUnknown

14l Pre Albumin mg/dL Missing Reason: Not DoneUnknown

14m Serum Albumin g/dL Missing Reason: Not DoneUnknown

14n Cholesterol Total Cholesterol


14o TG Triglycerides


14p LDL Low density lipoprotein




© 2017 PHTS [PHTS]

NYHA and Ross' Heart Failure

NYHA Classes

• Class I: No symptoms at any level of exertion and no limitation in ordinary physical activity.

• Class II: Mild symptoms and slight limitation during regular activity. Comfortable at rest.

• Class III: Noticeable limitation due to symptoms, even during minimal activity. Comfortable only at rest.

• Class IV: Severe limitations. Experience symptoms even while at rest (sitting in a recliner or watching TV).

Ross Heart Failure Classes

• Class I: No limitations or symptoms • Class II: Mild tachypnea and/or diaphoresis with feeds in infants; dyspnea on

exercise in older children. No growth failure. • Class III: Marked tachypnea and/or diaphoresis with feeds or exertion and

prolonged feeding time with growth failure.• Class IV: Symptomatic at rest with tachypnea, retractions, grunting or

diaphoresis.

14q HDL High density lipoprotein


14r VLDL Very low density lipoprotein


15 NYHA Class 1

2

3

4

Not Done

Unknown

16 Ross' Heart Failure Class 1

2

3

4

Not Done

Unknown



Calculated

BSA: n/aBMI: n/a


Height and Weight

Form 1RL: Relisting Not Started Print this Form

1 Date of Relisting





4 Has this patient been transplanted No

Yes

4a Indicate total number of prior transplants

This includes transplants that were and were not done

at your hospital.


4b Date of most recent transplant

MM/DD/YYYY

5 Main reason for Re-Listing Coronary artery disease, (infarction, arrhythmia, CHF post MI) Non-Specific Graft Failure (>30 days post transplant) Pulmonary Hypertension/RV Failure Rejection, acute Rejection Hyperacute (onset < 24 hours post transplant)

Rejection, Acute

Sudden Cardiac Death, no MI documented

Other, specify

6 Contributing reason for Re-Listing Coronary artery disease, (infarction, arrhythmia, CHF post MI)

Non-compliance

Non-specific graft failure (>30 days post transplant)

Pulmonary Hypertension/RV Failure

Rejection, acute

Page 1 of 14PHTS - Form 1RL: Relisting

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Status Details at Re-Listing

Rejection, hyperacute (onset < 24 hours post transplant)

Sudden cardiac death, no MI documented

Other, specify

7a Status at Re-Listing Brazil

Canada

United Kingdom

United States

7a.iv Status at Re-Listing, US 1 (this option is only for listings prior to 1999)

1A

1B

2

7

7a.ii Status at Re-Listing, Canada

0

1

2

3

3.5

4

7a.iii Status at Re-Listing, UK Routine

Urgent

7a.i Status at Re-Listing, Brazil Non-Priority

Priority

7b Was patient in or out of hospital at time of listing?

In hospital

Out of hospital

7b.i Was patient in the ICU at time of relisting?

No

Yes

Unknown



No

Yes

Unknown

7c Did the patient require continuous inotropes at time of listing?

Yes

No

Unknown



Infectious Disease Screening

7c.i Inotropes does Dose Unknown

High Dose or Multiple IV

Single Low Dose




Yes

No

Unknown

7e ABO incompatible No

Yes

Unknown

7f Was patient on a VAD or ECMO at time of relisting?

VAD

ECMO

Not on support at time of Relisting





organ?

Yes

No

Unknown


Not Applicable

8a HIV Serology AIDS testing


8b CMV Serology Negative Not Done Positive Unknown

8c CMV PCR Negative Not Done Positive Unknown

8d EBV Serology Negative Not Done Positive Unknown

8e EBV PCR Negative Not Done Positive Unknown

8f IFA Toxo Toxoplasma testing


8g HBs Ag Hepatitis B surface antigen




Medical History at time of Re-Listing

8h HB core Ab Hepatitis B core antibody


8i HBs Ab Hepatitis B surface antibody


8j Hep C Ab Hepatitis C antibody


8k RPR/Syphilis Syphilis testing


9 Medical History No

Yes

Unknown

9a Medical History Details Select all medical history the patient had at the time of

listing.

Arrhythmia (current heart only)

Cardiac arrest/CPR (current heart)

Diabetes

GI/Nutrition


Malignancy

Metabolic Disorder

Mitochondrial Disorder

Neurological

Pacemaker (current heart)

Peripheral myopathy/neuromuscular disease

Prenatal Diagnosis

Prior transfusions

Renal insufficency

Respiratory

Shock (current heart)

Syndrome

Other, specify

9a.i Arrhythmia Afib/flutter

Complete heart block

V Fibrilliation

V Tachycardia

Unknown

Other, specify

9a.ii Date of last cardiac arrest/CPR

MM/DD/YYYY


9a.xii Pacemaker Defibrillator/AICD

Pacemaker, CRT/Biventricular pacing



Pacemaker, not CRT and not ICD

9a.xii.3 Pacemaker,not CRT and

not ICD,Date placed

MM/DD/YYYY


9a.xii.2 Pacemaker,

CRT/Biventricular pacingDate placed

MM/DD/YYYY


9a.xii.1 Defibrillator/AICD,

Date Placed MM/DD/YYYY


9a.xvi Date of last appropriate Shock

MM/DD/YYYY


9a.iii Date of Last Hgb A1c MM/DD/YYYY


9a.iv Value of Last Hgb A1c Missing Reason: Not DoneUnknown

9a.v Treating with Insulin No

Yes

Unknown

9a.vi GI/Nutrition Failure to thrive/cachexia

Fontan associated liver disease

Infectious hepatitis

Protein losing Enteropathy

Other, specify

9a.vi.1 Hepatitis History

A

B

C

Unknown

Other, specify

9a.vii Heterotaxy/Isomerism Asplenia

Polysplenia

Situs inversus



Unspecified

Other, specify

9a.viii Malignancy Lymphoma, leukemia

s/p BMT

s/p Chest Radiation

Solid organ cancer

Unknown

Other, specify

9a.xi Neurologic Anoxic brain injury


Other, specify

9a.xi.1 Anoxic Brain Injury Date

MM/DD/YYYY


9a.xi.2 Hemorrhagic and/or

Thromboembolic Stroke,Date Last

MM/DD/YYYY


9a.xiii Peripheral myopathy/neuromuscular

disease

Becker muscular dystrophy

Duschenne muscular dystrophy

Freidrich's ataxia

Unspecified

Other, specify

9a.xv Respiratory Asthma

Plastic Bronchitis

Tracheostomy

Unknown

Other, specify

9a.xvii Syndrome Cardiofaciocutaneous syndrome

Costello syndrome

DiGeorge (22q11 deletion)

Down's/Trisomy 21

Ehlers-Danlos Syndrome

LEOPARD/Multiple Lentigenes

Loeys-Dietz Syndrome

Marfan Syndrome

Noonan syndrome



Insurance







Percent or Panel Reactive Antibody (closest to relisting)

Other Marfan-like syndrome

Turner Syndrome

Unspecified

Williams syndrome

Other, specify

9a.xiv Renal Insufficiency Dialysis, acute (within past 30 days)

Dialysis, chronic (>1 month duration)

Dysfunction, not dialysis

Unknown

Other, specify

9a.ix Specify Metabolic Disorder

9a.x Medical History, Mitochondrial Disorder,

specify

Barth's

Unspecified

Other, specify

10 Primary Insurance Charitable Donation

Free

Government

Private

Self Pay

Unknown

Other, specify



11a Cytotoxic PRA ie. Serum is tested against panel of lymphocytes

Done

Not Done

11a.i T Cell % Missing Reason: Not DoneUnknown

11a.ii B Cell % Missing Reason: Not DoneUnknown

11a.iii Date (Cytotoxic PRA) Missing Reason: Not DoneUnknown

11b Cytotoxic PRA, DTE/DTT Panel performed on serum treated with DTE or DTT (or

equivalent)

to reduce the IgM antibodies and identify high PRA results

presumably secondary to a drug or other causes.

Done

Not Done

11b.i T Cell % Missing Reason: Not DoneUnknown

11b.ii B Cell % Missing Reason: Not DoneUnknown

11b.iii Date (Cytotoxic PRA, DTE/DTT)


11c Flow Cytometry or Luminex PRA

Done

Not Done

11c.i Class I % Missing Reason: Unknown

11c.ii Class II % Missing Reason: Unknown

11c.iii Date MM/DD/YYYY


11d Re-listed for prospective crossmatch

No

Yes

Unknown

11d.i Prospective Crossmatch Type

Donor Cells

Donor Cells and Virtual

Virtual



Hemodynamics Prior to Re-ListingIndicate the hemodynamics even if the patient is on pressors or inotropes. Best hemodynamics are those performed during the administration of agents given specifically to lower the pulmonary arterial pressure or the pulmonary vascular resistance. All pressures should be listed in mmHg. If unclear, please consult with your PI.

Unknown

11d.i.1 Virtual Crossmatch

Avoidance of donor antigens to all antibodies present Avoidance of donor antigens to antibodies above pre-specified threshold Avoidance of donor antigens to C1q fixing antibodies only

Unknown

12 Were hemodynamics done prior to relisting?

No

Yes

Unknown

12a Date MM/DD/YYYY



12c RAm (RAP or CVP) Right Atrial Mean Pressure


12d PAm Pulmonary Artery Mean


12e PCW Mean Pulmonary Capillary Wedge Pressure


12f SVC Sat Oxygen Saturation in the SVC


12g AO Sat Aortic Saturation



area (BSA)

Woods Units x m2






Schooling

(BSA)

Woods Units x m2







12m Was patient on mechanical support

at time of Hemodynamics

No

Yes

Unknown

12n Hemodynamic Agents No

Yes

Unknown

12n.i Indicate agent for best

hemodynamics

100% O2

Dobutamine

Dopamine

Epinephrine

Isuproterenol (Isuprel)

Milrinone (Primacor)

Nesiritide

Nitric Oxide

Nitroglycerin


Norepinephrine

PGE (Alprostadil)

PGI (Flolan)

Phenylephrine/ Neosynephrine

Sildenafil

Vasopressin

Other, specify

13 Is patient in school? No

Not Applicable

Yes

Unknown

No



Exercise Test


13a Are they at the age appropiate level

Yes

Unknown

13b Are they in a special education class

No

Yes

Unknown

14 Was exercise test performed? No

Yes

Unknown

14a If test no, specify reason Age Inappropriate

Too Sick

Unknown

Other, specify



(should be listed in exercise report; if not,

exercise lab personnel should be able to provide this data)

% Missing Reason: Not DoneUnknown

14c Respiratory Value at Peak RER or Respiratory Quotient:R Value at peak is





effort.


14d Max VO2Maximum oxygen consumption

ml/kg/min Missing Reason: Not DoneUnknown



AST Aspartate transaminase (also SGOT)

U/L



15c Missing Reason: Not DoneUnknown






















NYHA and Ross' Heart Failure

NYHA Classes

• Class I: No symptoms at any level of exertion and no limitation in ordinary physical activity.

• Class II: Mild symptoms and slight limitation during regular activity. Comfortable at rest.

• Class III: Noticeable limitation due to symptoms, even during minimal activity. Comfortable only at rest.

• Class IV: Severe limitations. Experience symptoms even while at rest (sitting in a recliner or watching TV).

Ross Heart Failure Classes

• Class I: No limitations or symptoms • Class II: Mild tachypnea and/or diaphoresis with feeds in infants; dyspnea on

exercise in older children. No growth failure. • Class III: Marked tachypnea and/or diaphoresis with feeds or exertion and

prolonged feeding time with growth failure.• Class IV: Symptomatic at rest with tachypnea, retractions, grunting or

diaphoresis.







16 NYHA Class 1

2

3

4

Not Done

Unknown

17 Ross Heart Failure Class 1

2

3

4

Not Done

Unknown



Calculated

BSA: n/aBMI: n/a


Height and Weight

Status Details at Transplant

Form 1T: Transplant Not Started Print this Form

1 Date of Transplant MM/DD/YYYY

2 Simultaneous organ Check all that apply.

Kidney

Liver

None

Unknown

Other, specify

3 Type of Transplant Orthotopic: recipient heart is replaced by donor heart.

Heterotopic: donor heart is transplant into recipient without the

removal of

the recipient’s heart (also called piggy-back transplant)

Heterotopic

Orthotopic

Unknown





6a Status at Transplant Brazil

Canada

United Kingdom

United States

6a.iv United States 1 (this option is only for listings prior to 1999)

1A

1B

2

7

6a.i Brazil Non Priority

Priority

Page 1 of 10PHTS - Form 1T: Transplant

8/10/2017https://phts.uab.edu/WBDE/Transplant/Add/12388?printForm=1

6a.ii Canada 1

2

3

3.5

4

4S

6a.iii United Kingdon Routine

Urgent

6b Was patient in or out of hospital at time of transplant?

In hospital

Out of hospital

6b.i Was patient in the ICU at time of transplant?

Yes

No

Unknown



Yes

No

Unknown

6c Did the patient require continuous inotropes at time of transplant?

Yes

No

Unknown

6c.i Inotropes Dose High Dose or Multiple IV

Single Low Dose

Unknown




Yes

No

Unknown

6e Was the patient transplanted with an ABO incompatible

transplant?

No

Yes

Unknown

6f Was patient on a VAD or ECMO at time of transplant?

VAD

ECMO

Not on support at time of Transplant




Percent or Panel Antibody (closest to Transplant)




organ?

Yes

No

Unknown


Not Applicable

7a Cytotoxic PRA Done

Not Done

7a.i T Cell Values above 10 will require section 10:

Per-operative management for PRA to be

completed.

% Missing Reason: Unknown

7a.ii B Cell Values above 10 will require section 10:


completed.


7a.iii Date MM/DD/YYYY


7b Cytotoxic PRA DTE/DTT Done

Not Done

7b.i T Cell Values above 10 will require section 10:


completed.


7b.ii B Cell Values above 10 will require section 10:


completed.


7b.iii Date MM/DD/YYYY


7c Flow Cytometry or Luminex PRA Done

Not Done

7c.i Class I Values above 10 will require section 10:


completed.




Pre-Transplant Interventions for Elevated PRA

7c.ii Class II Values above 10 will require section 10:


completed.


7c.ii Date Missing Reason: Unknown

8 Did this patient have a virtual crossmatch?

No

Yes

Unknown

8a Crossmatch Results Negative

Positive

Unknown

9 Donor Specific or Retrospective Crossmatch performed?

No

Yes

Unknown

9a Crossmatch Results Negative

Not Done

Positive

Unknown

9b Was the crossmatch performed prior

to the decision to accept the donor?

No

Yes

Unknown

10a Did the patient receive treatment

to lower or manage an elevated PRA

while awaiting transplantation?

No

Yes

Unknown

10a.i Which therapy was administered?

Check all that apply.

Azathioprine (Imuran)

Bortezomib (Velcade)

Cytoxan (cyclophosphamide)

Immunoglobulin (IVIG, IV IgG)

Mycophenylate, MMF (Cellcept, Myfortic)

Plasmapheresis/plasma exchange

Rituximab (Rituxan)

Unknown

Other, specify



Peri-operative management for PRA

10a.ii How long was therapy administered?


Only for a pre-specified time/number of treatments: specify

Until Heart transplantation, regardless of subsequent PRA levels/sensitization profile Until PRA level reduced to 0%/patient no longer sensitized Until PRA/sensitization profile diminished to a pre-specified goal

Unknown

10b Was prophylactic plasmapheresis/

exchange performed in the peri-operative period

No

Yes

Unknown

10b.i Was this performed during

cardiopulmonary bypass?

No

Yes

Unknown

10b.ii Was this performed during the

immediate post-operative period?

No

Yes

Unknown

10b.ii.1 How many cycles?


10c Were there additional therapies, not routinely administered to

post transplant patients in your center,

given to this patient?

No

Yes

Unknown

10c.i Therapies administered Check all that apply.

Alemtuzumab (Campath)


Basiliximab (Simulect)



Eculizumab (Soliris)

Immunoglobulin (IVIG, IV IgG)

MMF (Cellcept, Myfortic)


Rituximab (Rituxan)

Steroids (methylprednisone, prednisone, orapred, prednisolone, solumederol, Medrol, etc.)

Other, specify



B Cell and T Cell Results

Labaratory Values (closest to time of transplant)Note: labs may have been collected on different dates.

11a B cell flow DSXM Negative Not Done Positive Unknown

11b B cell CDC/cytotoxicity DSXM Negative Not Done Positive Unknown

11c T cell flow DSXM Negative Not Done Positive Unknown

11d T cell CDC/cytotoxicity DSXM Negative Not Done Positive Unknown

12 Donor Specific Antigens (DSA) No

Yes

Unknown

12a Donor Specific Antigens (DSA) Results

Class I

Class II

Unknown

12b Was DSA compliment fixing?

(i.e. positive C1q assay)

No

Yes

Unknown











Hemodynamics (closest to transplant)Indicate the hemodynamics even if the patient is on pressors or inotropes. Best hemodynamics are those performed during the administration of agents given specifically to lower the pulmonary arterial pressure or the pulmonary vascular resistance. All pressures should be listed in mm Hg. If unclear, please confirm with your PI.

14 Hemodynamics No

Yes

Unknown

14a Date MM/DD/YYYY



14c RAm (RAP or CVP) Right atrial mean pressure


14d PAm Pulmonary artery mean


14e PCW Mean pulmonary capillary wedge pressure


14f SVC Sat Oxygen saturation in the SVC


14g AO Sat Aortic saturation



area (BSA)

Woods Units x m2 Missing Reason: Not DoneUnknown


(BSA)

Woods Units x m2 Missing Reason: Not DoneUnknown









Inotropes, Pressors, and Thyroid Hormones

14m Hemodynamic Agents No

Yes

Unknown

14m.i Indicate agent for best

hemodynamics Check all that apply.

100% O2

Dobutamine

Dopamine

Epinephrine


Milrinone

Nesiritide

Nitric Oxide

Nitroglycerine


Norepinephrine

PGE (Alprostadil)

PGI (Flolan)

Phenylephrine/Neosynephrine

Sildenafil

Vasopressin

Other, specify

14n Was patient on mechanical support

at time of Hemodynamics?

No

Yes

Unknown

15 Was recipient on inotropes, pressors,

or thyroid hormones at time of transplant?

No

Yes

Unknown

15a Inotropes, Pressors, or Thyroid Hormones

100% O2

Dobutamine

Dopamine

Epinephrine


Milrinone

Neosynephrine

Nesiritide

Nitric Oxide

Nitroglycerine


Norepinephrine (Levophed)

PGE (Alprostadil)

PGI (Flolan)

Phenylephrine/Neosynephrine



© 2017 PHTS [PHTS]

Cardiopulmonary bypass, donor ischemic, and technique of transplant

Sildenafil

T3 (Tri-iodothyronine)

T4 (Levothyroxine)

Vasopressin

Other, specify

16 Cardiopulmonary bypass time Report total number in minutes

minutes Missing Reason: Unknown

17 Total donor ischemic time Report minutes from recovery crossclamp

to removal of crosscramp after transplant


18 Technique of transplant Atrial

Bicaval

Unknown



Calculated

BSA: n/aBMI: n/a


Height and Weight

Form 2: Donor Not Started Print this Form

Transplant Date

1 Donor Age Indicate age in months, days, or years Days

Months Years


2 Donor Date of Birth Missing Reason: Unknown

3 Donor Height Centimeters Inches


4 Donor Weight Kilograms Pounds


5 Donor Sex Female

Male

Unknown

6 Donor Race Check all that apply.

American Indian or Alaskan Native

Asian

Black

Pacific Islander

White

Unknown

Other, specify

7 Hispanic or Latino Yes if of Mexican, Puerto Rican, Cuban,

Central or South American or other

Spanish culture of origin, regardless of race.

No

Yes

Unknown

8a Donor Date of Death MM/DD/YYYY


Page 1 of 5PHTS - Form 2: Donor

8/10/2017https://phts.uab.edu/WBDE/Donor/Add/12388?printForm=1

8b Donor Cause of Death Check only one.

Anoxia

Cerebrovascular

CNS Tumor

Head Trauma

Other, specify

8c Donor Mechanism of death Check only one.

Asphyxiation

Blunt Injury

Cardiovascular

CNS Infection

Drowning

Drug Intoxication

Electrical

Gunshot Wound

Seizure

Stab

Sudden Infant Death

Unknown

Other, specify

8d Donor Circumstances of death Alleged Child Abuse

Alleged Homicide

Alleged Suicide

Motor Vehicle Accident

Non-Motor Vehicle Accident

Unknown

Other, specify

9 Donor Downtime Previously called "Duration of Cardiac Arrest".

No

Yes

Unknown

9a Duration of Donor Downtime Previously called "Duration of Cardiac Arrest".

Enter duration in minutes.


10 Chest Compressions (CPR) No

Yes

Unknown

10a If yes, CPR Time Enter duration in minutes


11 Donor Blood Type A

AB



B

O

11a Blood type A subtype A1

A2

Unknown

12 Donor Rh Negative

Positive

Unknown

13 Donor Past Medical History Check all that are known.

Cancer at time of procurement

Diabetes

History of Cancer

Hypertension

Infection, specify

Mitral Valve Prolapse

None

Unknown

13a If donor had diabetes,was patient on insulin?

No

Yes

Unknown

13 Cancer at Time of Procurement, Location

13 Cancer Type/Location

14 Did the donor have an increased risk

for HIV, HBV, HCV?

No

Yes

Unknown

14a If yes, specify increased risk. At risk medical history (i.e. hemodialysis, new diagnosis of or treatment for STD in past 12 months)

At risk social history (specify)

Hemodiluted sample

14a.i If at risk social history, specify.

Check all that apply

Incarceration

Injected Drug Use

Mother with HIV

Sexual exposure

Unknown

Other, specify



Pre-transplant Donor Echocardiogram

Pre-transplant Donor Angiogram

Donor Serologies

15 Pre-Transplant Donor Echocardiogram

(closest to time of procurement)

No

Yes

Unknown

15a Result of Donor Echocardiogram

Abnormal

Normal

Unknown

15a.i If abnormal, please specify


Abnormal Septal Motion

Diffuse Wall Motion Abnormality

Focal Wall Motion Abnormality

Mitral Regurgitation

Tricuspid Regurgitation

Unknown

15b Donor Fractional Shortening Missing Reason: Not DoneUnknown

15c Donor Estimated LV Eject Fraction


16 Pre-transplant Donor Angiogram No

Yes

Unknown

16a Angiogram results Abnormal, Specify

Normal

Unknown

17a HIV Serology AIDS testing


17b CMV IgG Cytomegalovirus testing


17c IFA Toxo Toxoplasma testing




© 2017 PHTS [PHTS]

Donor on Inotropes, Pressors, or Thyroid Hormones at time of recovery/harvest?

17d EBV IgG Epstein Barr Virus


17e RPR/Syphilis Syphillis testing


17f HBs Ag Hepatitis B surface antigen


17g HB core Ab Hepatitis B core antibody


17h HBs Ab Hepatitis B surface antibody


17i Hep C ab Hepatitis C antibody


18a T3 Tri-iodothyronine (Thyroid hormone)

No Yes Unknown

18b T4 Levothyroxine (Thyroid hormone)

No Yes Unknown

18c Epinephrine Adrenaline (Inotrope, pressor)

No Yes Unknown

18d Dopamine (Inotrope)

No Yes Unknown

18e Dobutamine Dobutrex (Inotrope)

No Yes Unknown

18f Vasopressin Pitressin (Pituitary hormone)

No Yes Unknown

18g Levophed Norepinephrine (Inotrope, Pressor)

No Yes Unknown

18h Milrinone Primacor (Inotrope)

No Yes Unknown

18i Neosynephrine Phenylephrine (Pressor)

No Yes Unknown

18j Other No Yes Unknown

18j Please specify




Induction TherapyInduction Therapy is defined as the prescribed use of lymphocyte cytolytic antibody or IL2-R antagonist therapy (e.g., ATGAM, Thymoglobulin, Basiliximab, Daclizumab) given soon after transplant (started within 3 days), not used to specifically treat a known or suspected rejection episode).

The use of non-cytolytic agents pre or intraoperatively is not considered to be induction therapy.

Induction Agents

Induction Agent Details

Form 3: Initial Immunosuppression Not Started Print this Form

Transplant Date MM/DD/YYYY

1 Is Patient on Induction Therapy No

Yes

Unknown

1a Induction Immunosuppression Agent




Daclizumab (Zenapax)

OKT3

Rituximab (Rituxan)

Thymoglobulin (ATG)

Unknown

Other, specify

1b Start Date MM/DD/YYYY


1c End Date MM/DD/YYYY


2 Azathioprine (Imuran) No

Yes

Unknown

Page 1 of 6PHTS - Form 3: Initial Immunosuppression

8/10/2017https://phts.uab.edu/WBDE/InitialImmuno/Add/12388?printForm=1

2a Specify date of first post-op dose

MM/DD/YYYY

2b Was patient on medication at 30 days?

No

Yes

Unknown

2b.i If patient is no longer on medication

at 30 days, specify stop date.

MM/DD/YYYY


3 Cyclosporine No

Yes

Unknown


MM/DD/YYYY


No

Yes

Unknown



MM/DD/YYYY


4 Mycophenolate (Cellcept, Myfortic) No

Yes

Unknown


MM/DD/YYYY


No

Yes

Unknown



MM/DD/YYYY


No



5 Sirolimus (Rapamycin) Yes

Unknown


MM/DD/YYYY


No

Yes

Unknown



MM/DD/YYYY


6 Tacrolimus (Prograf, FK506) No

Yes

Unknown


MM/DD/YYYY


No

Yes

Unknown



MM/DD/YYYY


7 Everolimus No

Yes

Unknown


MM/DD/YYYY


No

Yes

Unknown





at 30 days, specify stop date. MM/DD/YYYY

8 Cyclophoshamide (Cytoxan) No

Yes

Unknown


MM/DD/YYYY


No

Yes

Unknown



MM/DD/YYYY


9a Was patient given pre-operative steroids?

No

Yes

Unknown

9b Was patient given intra-operative steroids?

No

Yes

Unknown

9c Was patient given post-operative steroids?

Yes

No

Unknown

9c.i Date of first post-op dose MM/DD/YYYY


9c.ii Daily dose at 30 days mg Missing Reason: No Steroids at 30 daysUnknown

9d Planned Maintenance Steroids No

Yes

Unknown

9d.i If no, please specify End Date of steroid use

MM/DD/YYYY


No



Other immunosuppressant details

Other immunosuppressant details

Prophylactic Antibiotics/Antivirals started Pre-op through 30 days post opInfection Prophylaxis: Started during the first 30 days post-transplant (not used to treat known infection).

10 Was patient given other immunosuppressants?

Yes

Unknown

10a Specify other immunosuppressant

10b Specify date of first post op dose

MM/DD/YYYY


10c Patient on medication at 30 days

No

Yes

Unknown

10c.i If patient is no longer on medication


MM/DD/YYYY


11 Prophylactic Antibiotics/Antivirals

started Pre-op through 30 days post op


Acyclovir

Antifungal

CMV Immunoglobulin (Cytogam)

Dapsone

Ganciclovir or Valganciclovir

Immunoglobulin (IV Ig)

Pentamidine

Trimethaprim-Sulfamethoxazole

Valacyclovir

Unknown

Other, specify

11a If antifungal, please specify


Fluconazole

Nystatin

Unspecified

Other, specify



© 2017 PHTS [PHTS]

11b If ganciclovir or valganciclovir, please

specify Check all that apply

IV

PO

12 Date of Hospital Discharge MM/DD/YYYY

Missing Reason: Still In HospitalUnknown




Coronary Evaluation

Angiography

Form 4: Coronary Evaluation Not Started Print this Form

1 Date of Coronary Evaluation

2 Indication for Coronary Evaluation Check only one.

Angio NOT DONE: Non-invasive test performed

Followup from PTCA / Revascularization (to check patency) Non-invasive test prior to this date indicated coronary disease

Objective evidence of graft dysfunction/CAD

Research Protocol

Routine, per established protocol (i.e. yearly evaluation)

Symptoms (suggesting CHF or angina equivalent)

Unknown

Other, specify

2b Non-invasive test prior to this date indicated coronary

disease, specify test Check only one.

Cardiac CT

Dobutamine Stress Echo

Exercise Test

MRI

Radionuclide Angiogram (MUGA)

Resting Echo

Stress Perfusion

Unknown

Other, specify

2a Angio NOT DONE: Non-invasive test performed

Cardiac CT

Dobutamine Stress Echo

Exercise Stress Echo

Exercise Test

MRI

Radionuclide Angiogram (MUGA)

Resting Echo

Stress Perfusion

Unknown

Other, specify

Page 1 of 7PHTS - Form 4: Coronary Evaluation

8/10/2017https://phts.uab.edu/WBDE/CoronaryEval/Add/12388?printForm=1

4b

Angiography Results

• ISHLT CAV 0 (Not significant): No detectable angiographic lesion• ISHLT CAV 1 (Mild): Angiographic left main (LM) <50%, or primary vessel with

maximum lesion of <70%, or any branch stenosis <70% (including diffuse narrowing) without allograft dysfunction

• ISHLT CAV 2 (Moderate): Angiographic LM <50%; a single primary vessel >70%, or isolated branch stenosis >70% in branches of 2 systems, without allograft dysfunction

• ISHLT CAV 3 (Severe): Angiographic LM >50%, or two or more primary vessels >70% stenosis, or isolated branch stenosis >70% in all 3 systems; or ISHLT CAV 1 or CAV 2 with allograft dysfunction (defined as LVEF <45% usually in the presence of regional wall motion abnormalities)

L Main = Left Main Coronary ArteryLAD = Left Anterior DescendingLCx = Left CircumflexRCA = Right Coronary ArteryPDA = Posterior Descending

3a Injection sites Check all that apply.

Aorta

Left Ventricle

Selective Left Coronary

Selective Right Coronary

Unknown

3b Method of Interpretation (Pertains to the angiogram)

Check only one.

Caliper

Computer Assisted

Visual Estimate

Unknown

3c Pre-angiogram nitroglycerin No

Yes

Unknown

4 Angiography Results Abnormal

Normal

Unknown

4a If abnormal, indicate ISHLT CAV score

(J Heart Lung Transplant July 2010;29(7):717-27)

0

1

2

3

Not Graded

Unknown

Normal

Not Visualized

Unknown

Absent (congenital)

Mild Stenosis (0% to 50%)

Moderate Stenosis (51% to 70%)

Severe Stenosis (71% to 100%)

Ectasia

L Main LAD LCx RCA PDA



Coronary FlowFunctional assessment of coronary flow performed using catheter-based methodsAbnormal Fractional Flow Reserve (FFR) is defined as <0.75Abnormal Coronary Flow Reserve (CFR) is defined as <2.0 Maximal Flow: Resting Flow

Intravascular Ultrasound

Severe Distal Pruning

5 Fractional Flow Reserve Performed No

Yes

Unknown

5a Vessels Studied Check all that apply.

LAD

LCx

Left Main

RCA

Unknown

5a.iii FFR Abnormal for Left Main Coronary

Artery (L Main)

No

Yes

Unknown

5a.i FFR Abnormal for Left Anterior Descending

(LAD)

No

Yes

Unknown

5a.ii FFR Abnormal for Left Circumflex (LCx)

No

Yes

Unknown

5a.iv FFR Abnormal for Right Coronary Artery

(RCA)

No

Yes

Unknown

6 Coronary Flow Reserve (CFR) Performed

No

Yes

Unknown

6a If CFR Performed, CFR abnormal

(Abnormal is defined as: ≤2.0 Maximal Flow: Resting

Flow)

No

Yes

Unknown

7 Intravascular Ultrasound Performed No

Yes



Unknown

7a Vessels Studied LAD

LCx

Left Main

RCA

Unknown

7a.v If Left Main, Maximal Intimal Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown

7a.vi If Left Main, Stanford Score

0

1

2

3

4

Not Done

Unknown

7a.i If LAD, Maximal Intimal Thickness

(MIT)

<0.3 mm

>= 0.3mm

Unknown

7a.ii If LAD, Stanford Score

0

1

2

3

4

Not Done

Unknown

7a.iii If LCx, Maximal Intimal Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown

7a.iv If LCx, Stanford Score

0

1

2

3

4

Not Done

Unknown

7a.vii If RCA, Maximal Intimal Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown



Left Ventricular Function Evaluation

7a.viii If RCA, Stanford Score

0

1

2

3

4

Not Done

Unknown

8 Left Ventricular Function Evaluation Nearest to coronary angiogram

No

Yes

Unknown

8a Date of study Missing Reason: Not DoneUnknown

8b Method of Interpretation Contrast ventriculogram

Echocardiogram

MRI

Radionuclide angiogram (MUGA)

Unknown

8c Left Ventricular Ejection Fraction


8d Echo Shortening Fraction Missing Reason: Not DoneUnknown

8e Wall Motion Akinesis

Dyskinesis

Hypokinesis

Normal

Not interpreted for wall motion abnormalities

Unknown

8e.iii Hypokinesis > 1 Segment

1 Segment

Diffuse

Unknown

8e.i Akinesis > 1 Segment

1 Segment

Diffuse

Unknown



Dobutamine or Exercise Stress Echo

8e.ii Dyskinesis > 1 Segment

1 Segment

Diffuse

Unknown

9 Was Dobutamine or Exercise Stress Echo performed?

Yes

No

Unknown

9a Date Missing Reason: Unknown

9b Maximum Dobutamine Dose mcg/kg/min Missing Reason: Not DoneUnknown

9c Baseline Akinesis/dyskinesis

Hypokinesis

Normal

9c.ii Is there segmental hypokinesis

and if so, how many segments?

> 1 Segment

1 Segment

Diffuse

Unknown

9c.i Is there segmental Akinesis/dyskinesis and if so, how many

segments?

> 1 Segment

1 Segment

Diffuse

less than 1

Unknown

9d Stress New Akinesis/dyskinesis

New Hypokinesis

Normal

9d.ii If Stress is New Hypokinesis

> 1 Segment

1 Segment

Diffuse

Unknown

9d.i If Stress is New

Akinesis/dyskinesis

> 1 Segment

1 Segment

Diffuse

Unknown



© 2017 PHTS [PHTS]

9e Maximum Heart Rate Achieved


9f LV Dilatation with Stress No

Yes

Unknown




Biopsy Prior to Rejection Event

Form 5: Rejection Not Started Print this Form

1 Select the baseline immunosuppressive therapy at time

of rejection

Azathioprine

Cyclosporine

Everolimus

Immune globulin

Methotrexate

Mycophenolate

Plasmapheresis

Prednisone

Rituximab

Sirolimus

Tacrolimus


Unknown

Other, specify

2 Biopsy Performed Prior to Rejection Event

If performed prior to this rejection diagnosis,

indicate the score of the most recent biopsy performed

that did not lead to rejection treatment.

No

Yes

2a Biopsy Date Prior to Rejection

MM/DD/YYYY


2b ACR Grading 2004 revised ISHLT grading system for ACR:

(J Heart Lung Transplant. 2005 Nov;24(11):1710-20.)

ACR: acute cellular rejection (0, 1R, 2R, 3R)

0R

1R

2R

3R

Unknown

2c AMR Grading 2013 revised ISHLT grading system for pAMR:

J Heart Lung Transplant 2013 Dec 32(12):1147-62.)

pAMR: pathologic antibody mediated rejection (0, 1h, 1i, 2, 3)

Both histology and immunofluorescence/immunohistochemistry performed (ie. C4d or C3d)

Did not assess biopsy for evidence of AMR

Only assessed histology/ did not perform immunofluorescence/immunohistochemistry (ie. C4d or C3d)

Unknown

2c.ii AMR Findings If only accessed histology/ did not

perform

immunofluorescene or immunohistochemistry (ie. C4d or C3d

No histologic features AMR

Positive histologic features AMR (ie. Vasculitis/ pericapillaritis)

Page 1 of 5PHTS - Form 5: Rejection

8/10/2017https://phts.uab.edu/WBDE/Rejection/Add/12388?printForm=1

Rejection EventsStart with newly diagnosed rejection by biopsy (convert to ISHLT score) or other criteria leading to bolus immunotherapy. List all follow-up biopsies or changes in therapy. The last entry should be the first biopsy or echo not prompting additional therapy. Enter each subsequent rejection event until episode is resolved.

2c.i pAMR Grading 2013 revised ISHLT grading system for

pAMR:



0 (negative)

1h

1i

2

3

Positive for AMR but pAMR score not known

3 Was donor specific Ab testing performed

at the time of the rejection event

No, Did not send testing for any circulating antibodies

Yes

Unknown

3a Which antibodies were tested and what were the results

HLA class I and/or class II DSA

Isoagglutinin (A or B Ab) to ABO-i graft

Non-HLA antibody (e.g. MICA, MICB, anti-endothelial, vimentin, anti-myosin, angiotensin receptor (AR1T), or other non-HLA

Unknown

3a.i HLA Class I and/or II DSA Result

Negative

Positive

Unknown

3a.i.1 HLA class I and/or II

DSA Result, Positive

Complement fixing (C1q positive)

Increased from last date tested

New

Present but stable (no new abs and not increased from baseline)

Unknown

3a.ii Non-HLA Ab Result Non-HLA antibody (e.g. MICA, MICB,

anti-endothelial, vimentin, anti-myosin,

angiotensin receptor (AR1T), or other non-HLA Results

Negative

Positive

Unknown

3a.ii.1 Non-HLA Ab Result,

Positive Non-HLA antibody (e.g. MICA, MICB, anti-endothelial, vimentin, anti-

myosin, angiotensin receptor (AR1T), or other non-HLA Results

Increased from last date tested

New

Present but stable (no new abs and not increased from baseline)

Unknown

3a.iii Isoagglutinin (A or B Ab)

to ABO-i graft Positive is defined as titer of 1:16 or higher

Negative

Positive

Unknown



Rejection Event

Date of rejection event Any episode leading to an increase in immunotherapy

to treat a biopsy or clinically diagnosed episode of rejection

MM/DD/YYYY

4a Basis for Diagnosis of Current Rejection Event

Biopsy

Clinical

ECHO

New or increased Abs

Unknown

4b Was biopsy performed? No

Yes

4b.i Indication for biopsy Check all that apply.

Objective Evidence of Graft Dysfunction

Research

Routine (scheduled as part of protocol surveillance)

Symptoms

4b.ii ACR Grading 2004 revised ISHLT grading system for ACR:

(J Heart Lung Transplant. 2005 Nov;24

(11):1710-20.)

ACR: acute cellular rejection (0, 1R, 2R, 3R)

0R

1R

2R

3R

Unknown

4b.iii AMR Grading 2013 revised ISHLT grading system for

pAMR:



Both histology and immunofluorescence/immunohistochemistry performed (ie. C4d or C3d)

Did not assess biopsy for evidence of AMR

Only assessed histology/ did not perform immunofluorescence/immunohistochemistry (ie. C4d or C3d)

Unknown

4b.iii.2 Histology results

No histologic features AMR

Positive histologic features AMR

4b.iii.1 If both histology and

immunofluorescence/immunohistochemistry performed,

indicate pAMR grading 2013 revised ISHLT grading system for pAMR:



0

1h

1i

2

3

Positive with Unknown Score

4c Was there therapy used to treat this rejection episode?

No

Yes



If no rejection therapy was used, no more rejection

episodes should be entered for this event.

4c.i Select the therapy used ATG or ATGAM

Bortezomib

Eculizumab

Immune Adsorption

Immunoglobulin

Methotrexate

Photopheresis

Plasmapheresis

Rituximab

Steroid Taper

Steroids, IV

Steroids, Oral

Tacrolimus


Other, specify

4d Was episode of rejection associated

with hemodynamic compromise?

None - No significant change in cardiac function at the time of rejection

Mild - Worsening of cardiac function detected (decreased ejection

fraction,

hypotension, EKG changes) not requiring inotropes.

Severe Inotropic support added due to this rejection episode.

Inotropic Support

Mild

None

Unknown

5 Indicate date of the end of the rejection episode

MM/DD/YYYY

6 Was there baseline immunosuppressive

therapy at time of resolution of rejection event

No

Yes

6a Baseline immunosuppressive therapy at time of resolution

of rejection event


Cyclosporine (Sandimmune, Neoral, Gengraf, CSA, CyA)

Everolimus

Immune globulin

Methotrexate

Mycophenolate (Cellcept, Myfortic)

Prednisone

Rituximab

Sirolimus (Rapamycin, Rapamune)

Tacrolimus (Prograf, FK506)

Cytoxan (Cyclophosphamide)



© 2017 PHTS [PHTS]

Unknown

Other, Specify




Form 6: Infection Not Started Print this Form

1 Evidence of Infectious Process Requiring IV Therapy

If "no" to both, infection does not meet definition of PHTS severe

infection

and form should not be completed.

Use a separate form for each infection episode and or type of infection.

No

Yes

Unknown

2 Life Threatening Infection Requiring Oral Therapy

No

Yes

Unknown

3 Date of Infection Date of diagnosis or clinical presentation, whichever date is

earliest.

MM/DD/YYYY

4 Drug Therapy at Time of Infection Indicate if there was an ongoing prophylactic drug therapy at time

(date)

of infection diagnosis (i.e. valganciclovir for CMV prophylaxis post-

transplant).

Do not include drugs that have been prescribed to treat a specific

previous

infection unless that previous infection is considered to be resolved

and the patient is now on long-term prophylaxis.

Do not include therapy for the current infection – to be included under

section 6.

No

Yes

Unknown

4a Specify drug therapy at time of infection.

Acyclovir


ATGAM




CMV Immunoglobulin, Cytogam

Cyclosporine


Dapsone

Everolimus (Certican)

Fluconazole

Ganciclovir or Valganciclovir

Immunoglobulin, IV Ig

Methotrexate


Nystatin

Oseltamivir

Pentamidine

Prednisone

Rituximab (Rituxan)

Sirolimus (Rapamycin)

Page 1 of 3PHTS - Form 6: Infection

8/10/2017https://phts.uab.edu/WBDE/Infection/Add/12388?printForm=1

Type of Organism(s)Indicate all organisms associated with the type of infection.

Tacrolimus (Prograf, FK506)

Thymoglobulin/ATG

Trimethaprim-sulfamethoxazole, Septra

Valacyclovir

Other, specify

4b Ganciclovir or Valganciclovir

IV

PO

6 Type of infection Use a separate form for each episode and/or type of infection.

Bacterial

Fungal

No Organism Identified

Protozoan

Viral

Unknown

6a Organism

7 Location of infection Check all that apply

Blood: Culture positive

Blood: PCR positive

Bone: Osteomyelitis

Central nervous system/ brain (ie. Meningitis /Encephalitis)

Chest tube site infection

Gastrointestinal infection (ie. Gastritis, colitis, infectious diarrhea)

Heart (includes endocarditis)

Hepatic/ liver: Infectious hepatitis

Intrabdominal/ Peritoneal: Peritonitis

Pericardium/ pericarditis

Renal/ kidney/Urinary tract

Respiratory (includes Pneumonia/ Bronchiolitis/Tracheitis/ Pleuritis)

Skin or soft tissue: Cellulitis/fasciitis

VAD infection

Wound infection within 30 days, deep sternal: Deep sternal wound infection with positive culture or treated with prolonged antibiotics beyond perioperative prophylaxis when culture not obtained or pre-treated involving muscle, bone, and/or mediastinum requiring operative intervention Wound infection within 30 days, superficial sternal: Superficial, soft tissue

Unknown

Other, specify

Yes



© 2017 PHTS [PHTS]

7a Was the blood infection directly

attributed to the presence of a central line

(ie. organism cultured from blood is not related to an infection

at another site)?

No

Unknown

7b VAD Infection Location Check all that apply

Cannulae

Driveline

Unknown

8 Location of patient Emergency care, no admit

In Hospital

Out of Hospital

Unknown

9 Intervention Check all that apply

Drug therapy : Oral

Drug therapy: IV or IM

Mechanical Ventilation

Surgical therapy, specify

Unknown

Other, specify

9a Intervention - Surgical therapy, specify

10 Outcome at 30 days post-date of infection Check only one.

Significant long term sequelae means

any residual medical problem persisting

for > 30 days after the onset

of the infection (e.g.)

renal failure, respiratory failure.

Death

Resolution

Significant Long Term Sequelae

Unresolved at 30 days

Unknown

10a If death occurred, did the infection

contribute to cause of death?

No

Yes

Unknown



Calculated

BSA: n/aBMI: n/a


Height and Weight

Form 7: Malignancy/Lymphoproliferative Disorder Not Started Print this Form

1 Date of Diagnosis MM/DD/YYYY

2a Height cm in


2b Weight kg lb


3 Patient Diagnosis Initial Diagnosis

Recurrence of previously diagnosed malignancy thought to be "cured."

Unknown

3a If recurrence, date of previous diagnosis

MM/DD/YYYY


4 Nature of Malignancy Check only one.

Complete additional form(s) for other malignancies.

Lymphoproliferative Disease/Lymphoma

Sarcoma

Skin

Unknown

Other, specify

5 Site(s) of involvement at initial diagnosis


Abdomen, not GI tract (retroperitoneum, intra-abdominal)

Bone

Bone Marrow

Breast

CNS

GI, Large Bowel

GI, Rectal

GI, Small Bowel

GI, Stomach

Heart

Hepatic

Kidney/Renal

Page 1 of 4PHTS - Form 7: Malignancy/Lymphoproliferative Disorder

8/10/2017https://phts.uab.edu/WBDE/MLDisease/Add/12388?printForm=1

Lymphoproliferative/LymphomaDetails of EBV seroconversion. Question 6a relates to whether patient has EBV seroconverted since transplant. That is, if they were EBV negative pre-transplant and become positive post-transplant, we want to capture that event and question 6a should be completed.

Lymph Nodes, deep

Lymph Nodes, subcutaneous

Mucous Membranes, genital/anal

Mucous Membranes, craniofacial

Muscle

Pulmonary (lungs)

Skin, facial scalp

Skin, non-facial

Spleen

Tonsils and/or adenoids

Unknown

Other, specify

6a Ebstein-Barr Seroconversion (negative pre transplant to

positive titer post-transplant)

No

Yes

Unknown

6a.i If Ebstein-Barr Seroconversion is Yes,

Date Last Negative EBV titer


6a.ii If Ebstein-Barr Seroconversion is Yes, Date last Positive EBV

titer


6b Was clonal analysis performed? No

Yes

Unknown

6b.i Clonal analysis results Monoclonal

Polyclonal

Both

Unknown

6b.ii Clonal analysis results B Cell

T Cell

Both

Unknown

6c EBV PCR Negative

Positive

Unknown



WHO Classification

Therapy at time of malignancy diagnosis and any changes made due to diagnosis within 30 days of diagnosis

Malignancy Lymph Disease Drug Details

6d EBV PCR: DNA copies/ml Missing Reason: Unknown

6e Is tumor EBV positive? No

Not Done

Yes

Unknown

7 WHO classification Hodgkin's/Hodgkin's-like

Monomorphic PTLD

Polymorphic PTLD

Unknown

Other, specify

7a If Monomorphic PTLD, specify

Burkitts

Diffuse large B cell

Other

Tcell lymphoma

8a Therapy at time of malignancy diagnosis

Acyclovir


Cyclophosphamide

Cyclosporine

Everolimus

Ganciclovir/Valganciclovir

Mycophenolate (Cellcept, Myfotic)

None

Rapamycin

Rituxan

Rituximab

Sirolimus (Rapamycin)

Steroids

Tacrolimus (FK506)

Unknown

Other, specify



© 2017 PHTS [PHTS]

Outcome at 30 days post diagnosis

8a.i If Therapy, Ganciclovir or Valganciclovir

IV

PO

8b Changes made due to diagnosis within 30 days of diagnosis

(specify)

Dose Decreased

Drug Added

Drug discontinued

No Change

Unknown

9 Additional therapeutic measures started within 30 days of diagnosis


Chemotherapy

Radiation therapy

Surgery (excision, not performed solely for diagnostic purposes)

Unknown

None

Other, specify

10 Did malignancy/PTLD resolve? No

Yes

Unknown

10a Was immune suppression decreased further from

above?

No

Yes

Unknown



Calculated

BSA: n/aBMI: n/a


Height and Weight

Form 8: Post Transplant Annual Followup Not Started Print this Form

1 Was patient seen for follow-up this year

Yes, patient was seen this year

No, patient was not seen this year or the patient follow-up falls outside the follow-up window (+/- 90 days of the transplant anniversary) No, patient transferred care to another center (not at time of annual follow-up)

7b Last Date of Followup at Your Center

2 Date of Follow-Up This is the date the patient was seen and the date for which the

data on the form is current.

It is not the date that the form is filled out.





5 Were Hemodynamics Performed? Yes

No

Unknown

5a Hemodynamics If done during annual surveillance biopsy (if

performed)

or during coronary assessment.

MM/DD/YYYY


5b AoM Aortic mean


5c RAm Right atrial mean


Page 1 of 7PHTS - Form 8: Post Transplant Annual Followup

8/10/2017https://phts.uab.edu/WBDE/Followup/Add/12388?printForm=1

Followup MedicationsAll medications that the patient was taking and prescribed at the time of the follow up date should be reported.Do not have to include PRN, topical, inhaled, or nebulizer medications.

Medication Details

5d PAm Pulmonary arterial mean


5e PCW LV EDP Pulmonary capillary wedge


5f C.O. Cardiac output


5g C.I. Cardiac Index


6 Current residence ZIP code/Postal Code


7 Is patient currently followed at your PHTS Transplant center?

Patient currently followed at our PHTS Transplant center

Patient followed exclusively at another center

7a If currently followed All care is provided at our center

Only yearly evaluation at our center

7a.i If only followed yearly,

specify date PHTS event followup ceased


7b Last Date of Followup at Your Center

8 Medications Missing Reason: NoneUnknown

9 Schooling Completed high school, >18 yo

Delayed grade level

Not applicable, <6 years

Special education

Status unknown









Within one grade level

10 Exercise Test No

Yes

Unknown

10a If exercise test not performed,

specify reason

Age inappropriate

Too sick

Unknown

Other, specify



(should be listed in exercise report; if not, exercise lab personnel

should be able to provide this data)

% Missing Reason: Not DoneUnknown

10b VO2 at follow-up Maximum oxygen consumption

ml/kg/min Missing Reason: Not DoneUnknown

10d Respiratory Value at Peak RER or Respiratory Quotient:R Value at peak is





effort.


11 Primary insurance at followup Charitable Donation

Free

Government

Private

Self Pay

Unknown

Other, specify






















12m Serum Albumin g/dL



Glomerular Filtritation Rate (GFR)

Viral Studies












13a GFR method 12 or 24 hour urine collection

Calculated, specify method

Nuclear medicine scan

Not Done

Unknown

13b Specify results

13b Specify Units

14a14a CMV serology Negative Not Done Positive Unknown

14b CMV PCR Negative Not Done Positive Unknown

14c EBV serology Negative Not Done Positive Unknown

EBV PCR



Events since transplant or last Form 8

14d Negative Not Done Positive Unknown

15a Coronary Evaluation If yes, complete form 4

No

Yes

15a.i Coronary Evaluation Event Date:

15b Rejection If yes, complete form 5

No

Yes

15b.i Rejection Event Date:

15c Infection If yes, complete form 6

No

Yes

15c.i Infection Event Date:

15d Malignancy/PTLD If yes, complete form 7

No

Yes

15d.i Malignancy Event Date:

15e Coronary Revascularization If yes, complete form 9

No

Yes

15e.i Coronary Revascularization Event

Date:

15f Death If yes, complete form 10

No

Yes

15f.i Death Event Date:

15g Retransplantation If yes, complete form 1RL, 1T, 2, and 3

No

Yes



© 2017 PHTS [PHTS]

15g.i Retransplantation Event Date:

15h Renal Transplant If yes, complete form 14

No

Yes

15h.i Renal Transplant Event Date:

15i Dialysis If yes, complete form 14

No

Yes

15i.i Dialysis Event Date:

15i.ii Acute Dialysis No

Yes

15i.iii Chronic Dialysis No

Yes

15j Diabetes requiring insulin No

Yes

15j.i Diabetes Event Date:

15k Other major events No

Yes

15k.i Other major events Event Date:




Functional Assessment of Coronary Flow Performed Using Catheter-Based Methods

Fractional Flow Reserve (FFR) Abnormal is defined as ≤0.75

Form 9: Coronary Revascularization Not Started Print this Form

1 Date of Procedure MM/DD/YYYY

2 Fractional Flow Reserve Performed? No

Yes

Unknown

2a Vessels Studied Check all that apply

LAD

LCx

Left Main

RCA

Unknown

2a.iii FFR Abnormal for Left Main Coronary

Artery (L Main)

No

Yes

Unknown

2a.i FFR Abnormal for Left Anterior

Descending (LAD)

No

Yes

Unknown

2a.ii FFR Abnormal for Left Circumflex

(LCx)

No

Yes

Unknown

2a.iv FFR Abnormal for Right Coronary

Artery (RCA)

No

Yes

Unknown

3 Coronary Flow Reserve (CFR) Performed

No

Yes

Unknown

3a CFR abnormal Abnormal is defined as ≤ 2.0 Maximal Flow: Resting

Flow)

No

Yes

Unknown

Page 1 of 4PHTS - Form 9: Coronary Revascularization

8/10/2017https://phts.uab.edu/WBDE/CoronaryRevasc/Add/12388?printForm=1

Intravascular Ultrasound

4 Intravascular Ultrasound Performed No

Yes

Unknown

4a Vessels studied LAD

LCx

Left Main

RCA

Unknown

4a.i If LAD, Median Intimal

Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown

4a.ii If LAD, Standford Score

0

1

2

3

4

Not Done

Unknown

4a.iii If LCx, Median Intimal

Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown

4a.iv If LCx, Standford Score

0

1

2

3

4

Not Done

Unknown

4a.v If Left Main, Median Intimal

Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown

4a.vi If Left Main, Standford Score

0

1

2

3

4

Not Done

Unknown



Percutaneous Procedures

Procedure Details

4a.vii If RCA, Median Intimal

Thickness (MIT)

<0.3 mm

>= 0.3mm

Unknown

4a.viii If RCA, Standford Score

0

1

2

3

4

Not Done

Unknown

5 Did the patient have a PTCA/Stent/Atheroctomy?

No

Yes

Unknown

5a Procedure AA (Angiojet Atherectomy)

DA (Directional Atherectomy)

PTCA (Angioplasty)

RA (Rotational Atherectomy)

Stent

Other, specify

5b Vessel LAD (Left Anterior Descending)

LCx (Left Circumflex)

Left Main Coronary Artery

PDA (Posterior Descending)

RCA (Right Coronary Artery)

Unknown

5c Lesion Characteristic Concentric

Eccentric

Tubular

Unknown

5d Location Distal

Mid

Proximal

Unknown

Pre Procedure Stenosis %



© 2017 PHTS [PHTS]

Coronary Artery Bypass Grafting

5e Missing Reason: Unknown

5f Post Procedure Stenosis % Missing Reason: Unknown

5g Comments on Procedure(s) done Missing Reason: None

6 Coronary Artery Bypass Grafting No

Yes

Unknown

6a Vessel LAD

LCx

Left Main

PDA

RCA

Unknown




*American Heart Association definition of Sudden Cardiac Death (also called sudden arrest) is death resulting from an abrupt loss of heart function (cardiac arrest). The victim may or may not have diagnosed heart disease. The time and mode of death are unexpected. It occurs within minutes after symptoms appear. Do not list support withdrawal as COD. Identify underlying reason – i.e .cardiac failure, pulmonary hemorrhage, irreversible brain injury, etc…

Form 10: Death Not Started Print this Form

1 Date of Death MM/DD/YYYY

2 Primary cause of death Check only one.

Cardiac

Hepatic Failure

Infection

Major bleeding

Malignancy/Cancer

Neurologic

Poor donor preservation

Primary graft failure (onset <24 hours post-transplant)

Pulmonary embolism

Pulmonary hypertension/RV failure

Rejection

Renal Failure

Respiratory failure

Suicide

Trauma/Accidental, specify

Unknown

Other, specify

2d If Neurologic, specify Check only one.

Anoxic insult

Stroke/Cerebrovascular accident

2a If Cardiac, specify Check only one.

Congestive heart failure

Coronary artery disease, (infarction)

Fatal arrhythmia

Sudden cardiac death, no arrhythmia or MI documented

2c If Malignancy/Cancer, specify Check only one.

Lymphoma/Lymphoproliferative disease

Malignancy, non-lymphoma

2b If Major Bleeding, specify Check only one.

Post-operative hemorrhage

Pulmonary hemorrhage

2e If Rejection, specify Check only one.

Acute

Chronic

Hyper acute (onset <24 hours post-transplant)

Page 1 of 5PHTS - Form 10: Death

8/10/2017https://phts.uab.edu/WBDE/Death/Add/12388?printForm=1

3 Did patient have a contributing cause of death?

Yes

No

Unknown

3a Cardiac

Family decision to withdraw of support

Hepatic Failure

Infection

Major bleeding

Malignancy/Cancer

Neurologic

Non-compliance

Poor donor preservation

Primary graft failure (onset <24 hours post-transplant)

Pulmonary embolism

Pulmonary hypertension/RV failure

Rejection

Renal Failure

Respiratory failure

Suicide

Trauma/Accidental, specify

Other, specify

Unknown

3a.i If Cardiac, specify Congestive heart failure

Coronary artery disease, (infarction)

Fatal arrhythmia

Sudden cardiac death, no arrhythmia or MI documented

Other, specify

3a.iii If Malignancy/Cancer,

specify

Lymphoma/Lymphoproliferative disease

Malignancy, non-lymphoma

Other, specify

3a.ii If Major Bleeding, specify

Post-operative hemorrhage

Pulmonary hemorrhage

Other, specify

3a.iv If Neurologic, specify

Anoxic insult

Stroke/Cerebrovascular accident

Other, specify



3a.v If Rejection, specify Hyperacute (onset < 24 hours post transplant)

Acute

Chronic

Other, specify

3a.vi If Trauma/Accidental,

specify

4 Patient supported by IABP/VAD/TAH/ECMO at time of

death

No

Yes

Unknown

5 Was patient listed or relisted at time of death?

No

Yes

Unknown

5a Status Details Check all that Apply Per UNOS Policy 6.1 On

6/14/2015

Has ductal dependent pulmonary or systemic circulation, with ductal patency maintained by stent of prostaglandin infusion

In hospital

Out of hospital

Requires Inotropes

5a.i ICU No

Yes

Unknown

5a.ii Requires continuous mechanical ventilationr

No

Yes

Unknown

5a.iii On inotropes High dose or multiple IV

Single low dose IV

Unknown Dose

5b ABO Incompatible No

Yes

Unknown

5c History of PRA > 10% No

Yes

Unknown

5c.i Did the patient receive treatment

to lower or manage an

No

Yes



2004 revised ISHLT grading system for ACR:(J Heart Lung Transplant. 2005 Nov;24(11):1710-20.)ACR: acute cellular rejection (0, 1R, 2R, 3R)

elevated PRA while awaiting transplantation?

5c.i.1 Which therapy was

administered?




Immunoglobin (IVIG, IV IgG)



Rituximab (Rituxan)

Other, specify

5c.i.2 How long was therapy

administered?

Only for a pre-specified time/number of treatments: specify Until Heart transplantation, regardless of subsequent PRA levels/sensitization profile Until PRA level reduced to 0%/patient no longer sensitized Until PRA/sensitization profile diminished to a pre-specified goal

Unknown

6 Post Mortem Examination (autopsy) No

Yes

6a Cardiac pathology found Check all that apply.

Acute Rejection

CAD, remote infarction (>1wk)

Coronary artery disease, recent infarction (<= 1wk)

Diffuse fibrosis, no acute rejection

Graftatherosclerosis

No cardiac pathology found

Other, specify

6a.i ACR Grading 0

1R

2R

3R

Unknown

6a.ii pAMR Grading 0

1h

1i

2

3

Not evaluated

Positive, score not specified



© 2017 PHTS [PHTS]

2013 revised ISHLT grading system for pAMR:J Heart Lung Transplant 2013 Dec 32(12):1147-62.)pAMR: pathologic antibody mediated rejection (0, 1h, 1i, 2, 3)

7 Were there special circumstances surrounding the death?

No

Yes

7a Comments



Calculated

BSA: n/aBMI: n/a


Height and Weight

Status

Followup Status Change

Form 12: Pre Transplant Status Report Not Started Print this Form

1 Was patient seen for follow-up this year?

Yes

No

1 Date of Follow Up MM/DD/YYYY

2 Height Indicate height at time of follow-up. Centimeters

Inches


3 Weight Indicate weight at time of follow-up. Kilograms

Pounds


4 Did the patient have any status changes since listing or the last

form 12?

Yes

No

Unknown

4a Current Status Brazil

Canada

United Kingdom

United States

4a.vii Old US Status Code 1 (this option is only for listings prior to 1999)

1A

1B

2

7

4a.viii New US Status Code 1 (this option is only for listings prior to 1999)

1A

1B

2

Page 1 of 5PHTS - Form 12: Pre Transplant Status Report

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7

4a.v Old United Kingdom Status Code

Routine

Urgent

Suspended

4a.vi New United Kingdom Status Code

Routine

Urgent

Suspended

4a.iii Old Canada Status Code 0

1

2

3

3.5

4

4S

4a.iv New Canada Status Code 0

1

2

3

3.5

4

4S

4a.i Old Brazil Status Code Non-Priority

Priority

4a.ii New Brazil Status Code Non-Priority

Priority

4b Reason for Status Change Age now > 6 months

Alternate medical treatment

Alternate surgical treatment

Deterioration

Financial

Improved

Infection

Neurological

Parent/patient reluctance

Psychosocial

Too Sick

Other, specify

4c Date of Status Code Change MM/DD/YYYY



Cardiac Surgery

Cardiac Surgery

5 Previous Cardiac Surgical History since listing or last follow-up?

No

Yes

Unknown

5a Surgical Intervention AP Shunt (includes BT shunt, Waterston, Pott's, Mee procedure, Central shunt)

ASD Repair

CABG

Complete AV Septal Defect Repair

Congenitally Corrected Transposition Repair (classic) Congenitally Corrected Transposition Repair (double switch)

Damus Kaye Stansel (DKS)

d-Transposition of the Great Vessels Repair

Ebstein's Anomaly Repair

Fontan Procedure

Glenn Procedure

Hybrid Palliation (PA banding and PDA stent with or without septostomy)

Norwood Procedure

Norwood Stage I: BT Shunt

Norwood Stage I: Sano/RV-PA conduit

PA Banding

Previous Heart Transplant

TOF/DORV/RVOTO Repair

Truncus Arteriosus Repair

Valve Replacement

VSD Repair

Other, specify

Unknown

5b Date of Surgical Intervention Missing Reason: Unknown

5a.i Arterial Switch Operation while Listed

Arterial switch operation

Atrial switch (Senning/Mustard)

Unknown

5a.ii Valve Replacement Details

Aortic valve replacement

Mitral valve replacement



Patient Status

Pulmonary valve replacement

Tricuspid valve replacement

Other, specify

5a.ii.1 Aortic Valve, Homograft

Tissue while Listed

No

Yes

Unknown

5a.ii.2 Pulmonary Valve,

Homograft Tissue while Listed

No

Yes

Unknown

6 Catheter interventions/device placements

Atrial Septostomy/Balloon Dilation of IAS

Balloon Dilation

Cardiac Resynchronization Therapy

Defibrillator/AICD

None

Pacemaker

Stent

Other, specify

6b If stent, specify location Arch

Atrial Septum

BT Shunt

Coronary artery

PDA

Pulmonary artery

Pulmonary vein

RV-PA conduit

Unknown

Other, specify

6a Balloon Dilation, specify location

7 Was patient permanently removed from Transplant Waiting List since

listed or last Form 12?

No

Yes

Unknown

Not Applicable, patient died or transplanted



© 2017 PHTS [PHTS]

Note: If patient was completely removed from the waiting list and is later

relisted, the new listing should be treated as a whole new patient.

7a If yes, specify date removed MM/DD/YYYY

7b If yes, specify reason removed

Alternate medical treatment

Alternate surgical treatment

Considered too well

Contraindications/too sick

Financial

Neurological

Parent/patient reluctance

Psychosocial

Other, specify

8 Followed exclusively elsewhere Note: If yes, no more data can be entered on this patient.

No

Yes

8a If yes, specify transfer date MM/DD/YYYY




Renal Transplant

DialysisDialysis includes temporary CVVH in which BUN, Urea, Creatinine are being lowered. Dialysis does not include ultrafiltration, the removal of fluid only with preserved renal function.

Laboratory Values Closet to Time of Dialysis or Renal TransplantNote: labs may have been collected on different dates

Form 14: Dialysis or Renal Transplant Not Started Print this Form

1 Renal Transplant No

Yes

Unknown

1a Date of renal transplant MM/DD/YYYY


1b Type of donor Deceased

Living, Related

Living, Unrelated

Unknown

2 Dialysis No

Yes

Unknown

2a Type of dialysis Acute

Both

Chronic

Unknown

2b Date of first dialysis related to this event report


2c Date of last dialysis related to this event


2d Type of dialysis Both

Hemodialysis

Peritoneal

Unknown

Page 1 of 3PHTS - Form 14: Dialysis or Renal Transplant

8/10/2017https://phts.uab.edu/WBDE/DsysRenTransplant/Add/12388?printForm=1


Form 15: Mechanical Circulatory Support Events Not Started Print this Form

1 Date of Initiation MM/DD/YYYY

2 Date of Discontinuation MM/DD/YYYY

If patient is still on MCSD support, check the "still in place" box.

Then, you may edit this form with the discontinuation date once the

support has been removed.

Missing Reason: Still in place

3 Type of Support ECMO

VAD

Other, specify

3a Type of ECMO Both

V-A

V-V

3b VAD Type LVAD alone

RVAD alone

TAH

3c Other temporary device brand

IABP

Impella

Other

3b.i VAD Brands LVAD

Abiomed AB5000

Abiomed BVS 5000

Abiomed Impella 2.5

Abiomed Impella 5.0

Berlin Heart EXCOR

Biomedicus

HeartMate II LVAS

HeartMate IP

HeartMate VE

HeartMate XVE

HeartWare HVAD

Impella CP

Maquet Rotaflow

Micromed DeBakey VAD - Child

Novacor PC

Novacor PCq

Sorin Revolution

Tandem Heart

Thoratec Centrimag (Levitronix)

Thoratec IVAD

Page 1 of 2PHTS - Form 15: Mechanical Circulatory Support Events

8/10/2017https://phts.uab.edu/WBDE/MCSupport/Add/12388?printForm=1

© 2017 PHTS [PHTS]

Thoratec Pedimag

Thoratec PVAD

Other, specify

3b.ii VAD Brands RVAD

Abiomed AB5000

Abiomed BVS 5000

Abiomed Impella 2.5

Abiomed Impella 5.0

Berlin Heart EXCOR

Biomedicus

HeartWare HVAD

Maquet Rotaflow

Sorin Revolution

Tandem Heart

Thoratec Centrimag (Levitronix)

Thoratec IVAD

Thoratec Pedimag

Thoratec PVAD

Impella CP

Impella RP

Other, specify

3b.iii VAD Brands TAH

AbioCor TAH

SynCardia CardioWest TAH

Other, specify

Page 2 of 2PHTS - Form 15: Mechanical Circulatory Support Events

8/10/2017https://phts.uab.edu/WBDE/MCSupport/Add/12388?printForm=1

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